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A Virus‐Mimetic Nanogel Vehicle
Open accessAbstract
Delivering the goods: A pH-sensitive nanogel consists of a hydrophobic copolymer core and two layers of hydrophilic shell (see picture). The core is loaded with a model anticancer drug, doxorubicin (DOX). The nanogel infects tumor cells in a receptor-dependent manner, kills the cells, and migrates to neighboring cells like a virus. BSA=bovine serum albumin, F=folate, PEG=polyethylene glycol.
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Citations
Cited by
Stimuli-responsive nanocarriers for drug delivery
Mura, S., Nicolas, J., & Couvreur, P. (2013) · Nature Materials · doi:10.1038/nmat3776 · Cited by 6,289
Polymers for Drug Delivery Systems
Liechty, W. B., Kryscio, D. R., Slaughter, B. V., & Peppas, N. A. (2010) · Annual Review of Chemical and Biomolecular Engineering · doi:10.1146/annurev-chembioeng-073009-100847 · Cited by 1,608
Biodegradable synthetic polymers: Preparation, functionalization and biomedical application
Tian, H., Tang, Z., Zhuang, X., Chen, X., & Jing, X. (2012) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2011.06.004 · Cited by 1,293
Barua, S., & Mitragotri, S. (2014) · Nano Today · doi:10.1016/j.nantod.2014.04.008 · Cited by 1,257
pH-Responsive carriers for oral drug delivery: Challenges and opportunities of current platforms
Liu, L., Yao, W., Rao, Y., Lu, X., & Gao, J. (2017) · Drug Delivery · doi:10.1080/10717544.2017.1279238 · Cited by 420
Metadata
- Authors
- Lee, E. S., Kim, D., Youn, Y. S., Oh, K. T., & Bae, Y. H.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2008-03-10
- Volume
- 47
- Issue
- 13
- Pages
- 2418-2421
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2112579649
- Cited by
- 215
- References
- 0
- FWCI
- 8.91
- Type
- journal article
- Language
- en
- Open access
- green
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- Lee, E. S., Kim, D., Youn, Y. S., Oh, K. T., & Bae, Y. H. (2008). A Virus‐Mimetic Nanogel Vehicle. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.200704121
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
