Biodegradable synthetic polymers: Preparation, functionalization and biomedical application

Tissue engineering

Langer, R., & Vacanti, J. P. (1993) · Science · doi:10.1126/science.8493529 · Cited by 9,893 · see citing works

Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics

Michalet, X., Pinaud, F. F., Bentolila, L. A., Tsay, J. M., Doose, S., Li, J. J., Sundaresan, G., Wu, A. M., Gambhir, S. S., & Weiss, S. (2005) · Science · doi:10.1126/science.1104274 · Cited by 7,794 · see citing works

Poly(N-isopropylacrylamide): experiment, theory and application

Schild, H. G. (1992) · Progress in Polymer Science · doi:10.1016/0079-6700(92)90023-r · Cited by 5,162 · see citing works

Biodegradable polymers as biomaterials

Nair, L. S., & Laurencin, C. T. (2007) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2007.05.017 · Cited by 4,416 · see citing works

Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering

Rezwan, K., Chen, Q. Z., Blaker, J. J., & Boccaccini, A. R. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.01.039 · Cited by 3,840 · see citing works

Synthetic biodegradable polymers as orthopedic devices

Middleton, J. C., & Tipton, A. J. (2000) · Biomaterials · doi:10.1016/s0142-9612(00)00101-0 · Cited by 2,741 · see citing works

Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots

Wu, X., Liu, H., Liu, J., Haley, K. N., Treadway, J. A., Larson, J., Ge, N., Peale, F., & Bruchez, M. P. (2002) · Nature Biotechnology · doi:10.1038/nbt764 · Cited by 2,506 · see citing works

Nanoparticle and targeted systems for cancer therapy

Brannon‐Peppas, L., & Blanchette, J. O. (2004) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2004.02.014 · Cited by 2,335 · see citing works

In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis

Fischer, D., Li, Y., Ahlemeyer, B., Krieglstein, J., & Kissel, T. (2003) · Biomaterials · doi:10.1016/s0142-9612(02)00445-3 · Cited by 2,329 · see citing works

The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices

Jain, R. A. (2000) · Biomaterials · doi:10.1016/s0142-9612(00)00115-0 · Cited by 2,214 · see citing works

ZnO – nanostructures, defects, and devices

Schmidt‐Mende, L., & MacManus‐Driscoll, J. L. (2007) · Materials Today · doi:10.1016/s1369-7021(07)70078-0 · Cited by 2,022 · see citing works

Biodegradable block copolymers as injectable drug-delivery systems

Jeong, B., Bae, Y. H., Lee, D. S., & Kim, S. W. (1997) · Nature · doi:10.1038/42218 · Cited by 1,999 · see citing works

Phase II, Randomized Trial Comparing Bevacizumab Plus Fluorouracil (FU)/Leucovorin (LV) With FU/LV Alone in Patients With Metastatic Colorectal Cancer

Kabbinavar, F. F., Hurwitz, H. I., Fehrenbacher, L., Meropol, N. J., Novotny, W. F., Liebérman, G., Griffing, S., & Bergsland, E. K. (2002) · Journal of Clinical Oncology · doi:10.1200/jco.2003.10.066 · Cited by 1,711 · see citing works

Stimuli responsive polymers for biomedical applications

Alarcón, C. D. L. H., Pennadam, S. S., & Alexander, C. (2005) · Chemical Society Reviews · doi:10.1039/b406727d · Cited by 1,692 · see citing works

Bone Tissue Engineering: State of the Art and Future Trends

Salgado, A. J., Coutinho, O. P., & Reis, R. L. (2004) · Macromolecular Bioscience · doi:10.1002/mabi.200400026 · Cited by 1,680 · see citing works

Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo

Farokhzad, O. C., Cheng, J., Teply, B. A., Sherifi, I., Jon, S., Kantoff, P. W., Richie, J. P., & Langer, R. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601755103 · Cited by 1,667 · see citing works

Ligand-targeted therapeutics in anticancer therapy

Allen, T. M. (2002) · Nature reviews. Cancer · doi:10.1038/nrc903 · Cited by 1,648 · see citing works

In vivo imaging of tumors with protease-activated near-infrared fluorescent probes

Weissleder, R., Tung, C., Mahmood, U., & Bogdanov, A. A., Jr. (1999) · Nature Biotechnology · doi:10.1038/7933 · Cited by 1,591 · see citing works

Iron oxide MR contrast agents for molecular and cellular imaging

Bulte, J. W. M., & Kraitchman, D. L. (2004) · NMR in Biomedicine · doi:10.1002/nbm.924 · Cited by 1,500 · see citing works

Polymer surface modification for the attachment of bioactive compounds

Goddard, J. M., & Hotchkiss, J. H. (2007) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2007.04.002 · Cited by 1,383 · see citing works

Thermoresponsive hydrogels in biomedical applications

Klouda, L., & Mikos, A. G. (2008) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2007.02.025 · Cited by 1,349 · see citing works

Polymeric Scaffolds for Bone Tissue Engineering

Liu, X., & Ma, P. X. (2004) · Annals of Biomedical Engineering · doi:10.1023/b:abme.0000017544.36001.8e · Cited by 1,346 · see citing works

Design of Environment‐Sensitive Supramolecular Assemblies for Intracellular Drug Delivery: Polymeric Micelles that are Responsive to Intracellular pH Change

Bae, Y., Fukushima, S., Harada, A., & Kataoka, K. (2003) · Angewandte Chemie International Edition · doi:10.1002/anie.200250653 · Cited by 1,329 · see citing works

Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems

Nasongkla, N., Bey, E., Ren, J., Ai, H., Khemtong, C., Guthi, J. S., Chin, S.-F., Sherry, A. D., Boothman, D. A., & Gao, J. (2006) · Nano Letters · doi:10.1021/nl061412u · Cited by 1,238 · see citing works

Poly(ethylenimine) and its role in gene delivery

Godbey, W. T., Wu, K. K., & Mikos, A. G. (1999) · Journal of Controlled Release · doi:10.1016/s0168-3659(99)00090-5 · Cited by 1,200 · see citing works

Reduction-sensitive polymers and bioconjugates for biomedical applications

Meng, F., Hennink, W. E., & Zhong, Z. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.01.026 · Cited by 1,132 · see citing works

Antibody Targeting of Long-Circulating Lipidic Nanoparticles Does Not Increase Tumor Localization but Does Increase Internalization in Animal Models

Kirpotin, D. B., Drummond, D. C., Shao, Y., Shalaby, M. R., Hong, K., Nielsen, U. B., Marks, J. D., Benz, C. C., & Park, J. W. (2006) · Cancer Research · doi:10.1158/0008-5472.can-05-4199 · Cited by 1,129 · see citing works

Stimulation of neurite outgrowth using an electrically conducting polymer

Schmidt, C. E., Shastri, V. P., Vacanti, J. P., & Langer, R. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.17.8948 · Cited by 1,072 · see citing works

Peptide-Labeled Near-Infrared Quantum Dots for Imaging Tumor Vasculature in Living Subjects

Cai, W., Shin, D., Chen, K., Gheysens, O. S., Cao, Q., Wang, S. X., Gambhir, S. S., & Chen, X. S. (2006) · Nano Letters · doi:10.1021/nl052405t · Cited by 949 · see citing works

Degradable poly (β-amino esters): synthesis, characterization, and self-assembly with plasmid DNA

Lynn, D. M., & Langer, R. (2000) · Journal of the American Chemical Society · doi:10.1021/ja0015388 · Cited by 924 · see citing works

Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines. Physiologic and clinical implications

Ross, J. F., Chaudhuri, P. K., & Ratnam, M. (1994) · Cancer · doi:10.1002/1097-0142(19940501)73:9 · Cited by 886 · see citing works

Antibiofouling Polymer-Coated Gold Nanoparticles as a Contrast Agent for in Vivo X-ray Computed Tomography Imaging

Kim, D., Park, S.-J., Lee, J. H., Jeong, Y. Y., & Jon, S. (2007) · Journal of the American Chemical Society · doi:10.1021/ja071471p · Cited by 876 · see citing works

In situ gelling stimuli-sensitive block copolymer hydrogels for drug delivery

He, C., Kim, S. W., & Lee, D. S. (2008) · Journal of Controlled Release · doi:10.1016/j.jconrel.2008.01.005 · Cited by 870 · see citing works

Lessons from nature: stimuli-responsive polymers and their biomedical applications

Jeong, B., & Gutowska, A. (2002) · Trends in biotechnology · doi:10.1016/s0167-7799(02)01962-5 · Cited by 859 · see citing works

Synthetic polymer scaffolds for tissue engineering

Place, E., George, J. H., Williams, C. K., & Stevens, M. M. (2009) · Chemical Society Reviews · doi:10.1039/b811392k · Cited by 820 · see citing works

Impact of tumor-specific targeting on the biodistribution and efficacy of siRNA nanoparticles measured by multimodality in vivo imaging

Bartlett, D. W., Su, H. C., Hildebrandt, I. J., Weber, W., & Davis, M. E. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0707461104 · Cited by 808 · see citing works

Initial and 6-Month Results of Biodegradable Poly- l -Lactic Acid Coronary Stents in Humans

Tamai, H., Igaki, K., Kyo, E., Kosuga, K., Kawashima, A., Matsui, S., Komori, H., Tsuji, T., Motohara, S., & Uehata, H. (2000) · Circulation · doi:10.1161/01.cir.102.4.399 · Cited by 807 · see citing works

Coumarins in Polymers: From Light Harvesting to Photo-Cross-Linkable Tissue Scaffolds

Trenor, S. R., Shultz, A. R., Love, B. J., & Long, T. E. (2004) · Chemical Reviews · doi:10.1021/cr030037c · Cited by 791 · see citing works

Prospects for cationic polymers in gene and oligonucleotide therapy against cancer

Merdan, T., Kopec̆ek, J., & Kissel, T. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(02)00046-7 · Cited by 785 · see citing works

Antibody targeted drugs as cancer therapeutics

Schrama, D., Reisfeld, R. A., & Becker, J. C. (2006) · Nature Reviews Drug Discovery · doi:10.1038/nrd1957 · Cited by 769 · see citing works

Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property: tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy

Bae, Y., Nishiyama, N., Fukushima, S., Koyama, H., Yasuhiro, M., & Kataoka, K. (2005) · Bioconjugate Chemistry · doi:10.1021/bc0498166 · Cited by 742 · see citing works

Biodegradable injectable in situ forming drug delivery systems

Hatefi, A., & Amsden, B. G. (2002) · Journal of Controlled Release · doi:10.1016/s0168-3659(02)00008-1 · Cited by 728 · see citing works

Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers

Gu, F., Zhang, L., Teply, B. A., Mann, N., Wang, A. Z., Radovic‐Moreno, A. F., Langer, R., & Farokhzad, O. C. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0711714105 · Cited by 714 · see citing works

Stimuli-responsive polymers and their applications in drug delivery

Bawa, P., Pillay, V., Choonara, Y. E., & du Toit, L. C. (2009) · Biomedical Materials · doi:10.1088/1748-6041/4/2/022001 · Cited by 643 · see citing works

Folate receptor targeted biodegradable polymeric doxorubicin micelles

Yoo, H. S., & Park, T. G. (2004) · Journal of Controlled Release · doi:10.1016/j.jconrel.2004.02.003 · Cited by 620 · see citing works

Super pH-Sensitive Multifunctional Polymeric Micelle

Lee, E. S., Na, K., & Bae, Y. H. (2005) · Nano Letters · doi:10.1021/nl0479987 · Cited by 611 · see citing works

Fabrication of nano-structured porous PLLA scaffold intended for nerve tissue engineering

Yang, F., Ramalingam, M., Ramakrishna, S., Wang, X., Ma, Y.-X., & Wang, S. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2003.08.062 · Cited by 604 · see citing works

PEG Branched Polymer for Functionalization of Nanomaterials with Ultralong Blood Circulation

Prencipe, G., Tabakman, S. M., Welsher, K., Liu, Z., Goodwin, A. P., Zhang, L., Henry, J. P., & Dai, H. (2009) · Journal of the American Chemical Society · doi:10.1021/ja809086q · Cited by 602 · see citing works

Surface modification and property analysis of biomedical polymers used for tissue engineering

Ma, Z., Mao, Z., & Gao, C. (2007) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2007.06.019 · Cited by 590 · see citing works

Fabrication and biocompatibility of polypyrrole implants suitable for neural prosthetics.

George, P. M., Lyckman, A., Laván, D., Hegde, A., Leung, Y., Avasare, R., Testa, C., Alexander, P. M., Langer, R., & Sur, M. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2004.09.037 · Cited by 560 · see citing works

Synthetic polypeptides for biomedical applications

Deming, T. J. (2007) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2007.05.010 · Cited by 555 · see citing works

Chitosan as a nonviral gene delivery system. Structure–property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo

Köping‐Höggård, M., Tubulekas, I., Guan, H., Edwards, K., Nilsson, M., Vårum, K. M., & Artursson, P. (2001) · Gene Therapy · doi:10.1038/sj.gt.3301492 · Cited by 532 · see citing works

Electrical stimulation alters protein adsorption and nerve cell interactions with electrically conducting biomaterials

Kotwal, A. (2001) · Biomaterials · doi:10.1016/s0142-9612(00)00344-6 · Cited by 522 · see citing works

Polylysine-based transfection systems utilizing receptor-mediated delivery

Zauner, W., Ogris, M., & Wagner, E. (1998) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(97)00110-5 · Cited by 507 · see citing works

Polymeric nanomedicine for cancer therapy

Park, J. H., Lee, S., Kim, J.-H., Park, K., Kim, K., & Kwon, I. C. (2008) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2007.09.003 · Cited by 506 · see citing works

Aliphatic cyclic carbonates and spiroorthocarbonates as monomers

Rokicki, G. (2000) · Progress in Polymer Science · doi:10.1016/s0079-6700(00)00006-x · Cited by 499 · see citing works

Synthesis, properties, and biodegradation of poly(1,3-trimethylene carbonate)

Zhu, K. J., Hendren, R. W., Jensen, K., & Pitt, C. G. (1991) · Macromolecules · doi:10.1021/ma00008a008 · Cited by 499 · see citing works

Polymer Microneedles for Controlled-Release Drug Delivery

Park, J., Allen, M. G., & Prausnitz, M. R. (2006) · Pharmaceutical Research · doi:10.1007/s11095-006-0028-9 · Cited by 495 · see citing works

Bioresponsive hydrogels

Ulijn, R. V., Bibi, N., Jayawarna, V., Thornton, P. D., Todd, S. J., Mart, R. J., Smith, A. M., & Gough, J. E. (2007) · Materials Today · doi:10.1016/s1369-7021(07)70049-4 · Cited by 486 · see citing works

Fiber-based tissue-engineered scaffold for ligament replacement: design considerations and in vitro evaluation

Cooper, J. A., Lu, H. H., Ko, F., Freeman, J. W., & Laurencin, C. T. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2004.05.014 · Cited by 481 · see citing works

Small-Diameter Artificial Arteries Engineered In Vitro

Isenberg, B. C., Williams, C., & Tranquillo, R. T. (2006) · Circulation Research · doi:10.1161/01.res.0000196867.12470.84 · Cited by 470 · see citing works

Stimuli-responsive polymer vesicles

Li, M., & Keller, P. (2009) · Soft Matter · doi:10.1039/b815725a · Cited by 466 · see citing works

Magnetite-loaded polymeric micelles as ultrasensitive magnetic-resonance probes

Ai, H., Flask, C., Weinberg, B., Shuai, X. ‐., Pagel, M. D., Farrell, D., Duerk, J., & Gao, J. (2005) · Advanced Materials · doi:10.1002/adma.200401904 · Cited by 465 · see citing works

Poly(l-histidine)–PEG block copolymer micelles and pH-induced destabilization

Lee, E. S., Shin, H. J., Na, K., & Bae, Y. H. (2003) · Journal of Controlled Release · doi:10.1016/s0168-3659(03)00205-0 · Cited by 452 · see citing works

Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer

Boeckle, S., von Gersdorff, K., van der Piepen, S., Culmsee, C., Wagner, E., & Ogris, M. (2004) · The Journal of Gene Medicine · doi:10.1002/jgm.598 · Cited by 447 · see citing works

cRGD‐Functionalized Polymer Micelles for Targeted Doxorubicin Delivery

Nasongkla, N., Shuai, X., Ai, H., Weinberg, B. D., Pink, J. J., Boothman, D. A., & Gao, J. (2004) · Angewandte Chemie International Edition · doi:10.1002/anie.200460800 · Cited by 434 · see citing works

Polymer systems for gene delivery—Past, present, and future

Wong, S. Y., Pelet, J. M., & Putnam, D. A. (2007) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2007.05.007 · Cited by 428 · see citing works

Synthesis of a Novel, Biodegradable Electrically Conducting Polymer for Biomedical Applications

Rivers, T. J., Hudson, T. W., & Schmidt, C. E. (2002) · Advanced Functional Materials · doi:10.1002/1616-3028(20020101)12:1 · Cited by 423 · see citing works

Synthetic Polypeptide Mimics of Marine Adhesives

Yu, M., & Deming, T. J. (1998) · Macromolecules · doi:10.1021/ma980268z · Cited by 421 · see citing works

Poly(l-glutamic acid)–anticancer drug conjugates

Li, C. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(02)00045-5 · Cited by 414 · see citing works

A Protein Nanocarrier from Charge-Conversion Polymer in Response to Endosomal pH

Lee, Y., Fukushima, S., Bae, Y., Hiki, S., Ishii, T., & Kataoka, K. (2007) · Journal of the American Chemical Society · doi:10.1021/ja071090b · Cited by 405 · see citing works

Magnetite Nanoparticle Dispersions Stabilized with Triblock Copolymers

Harris, L. A., Goff, J. D., Carmichael-Baranauskas, A. Y., Riffle, J. S., Harburn, J. J., Pierre, T. G. S., & Saunders, M. (2003) · Chemistry of Materials · doi:10.1021/cm020994n · Cited by 401 · see citing works

Super pH-sensitive multifunctional polymeric micelle for tumor pHe specific TAT exposure and multidrug resistance

Lee, E. S., Gao, Z., Kim, D., Park, K., Kwon, I. C., & Bae, Y. H. (2008) · Journal of Controlled Release · doi:10.1016/j.jconrel.2008.04.024 · Cited by 400 · see citing works

PEG-Detachable Polyplex Micelles Based on Disulfide-Linked Block Catiomers as Bioresponsive Nonviral Gene Vectors

Takae, S., Miyata, K., Oba, M., Ishii, T., Nishiyama, N., Itaka, K., Yamasaki, Y., Koyama, H., & Kataoka, K. (2008) · Journal of the American Chemical Society · doi:10.1021/ja800336v · Cited by 400 · see citing works

Accelerated Discovery of Synthetic Transfection Vectors: Parallel Synthesis and Screening of a Degradable Polymer Library

Lynn, D. M., Anderson, D. G., Putnam, D. A., & Langer, R. (2001) · Journal of the American Chemical Society · doi:10.1021/ja016288p · Cited by 395 · see citing works

Parallel Synthesis and Biophysical Characterization of a Degradable Polymer Library for Gene Delivery

Akinc, A., Lynn, D. M., Anderson, D. G., & Langer, R. (2003) · Journal of the American Chemical Society · doi:10.1021/ja034429c · Cited by 376 · see citing works

Polyarginine segments in block copolypeptides drive both vesicular assembly and intracellular delivery

Holowka, E. P., Sun, V. Z., Kamei, D. T., et al. (2006) · Nature Materials · doi:10.1038/nmat1794 · Cited by 372 · see citing works

Fabrication and Endothelialization of Collagen-Blended Biodegradable Polymer Nanofibers: Potential Vascular Graft for Blood Vessel Tissue Engineering

He, W., Yong, T., Teo, W. E., et al. (2005) · Tissue Engineering · doi:10.1089/ten.2005.11.1574 · Cited by 371 · see citing works

Characterization of Vectors for Gene Therapy Formed by Self-Assembly of DNA with Synthetic Block Co-Polymers

Wolfert, M. A., Schacht, E. H., Toncheva, V. D., Ulbrich, K., Nazarova, O. V., & Seymour, L. W. (1996) · Human Gene Therapy · doi:10.1089/hum.1996.7.17-2123 · Cited by 365 · see citing works

Local and systemic delivery of VEGF siRNA using polyelectrolyte complex micelles for effective treatment of cancer

Kim, S. H., Jeong, J. H., Hyeon, L. S., Kim, S. W., & Park, T. G. (2008) · Journal of Controlled Release · doi:10.1016/j.jconrel.2008.03.008 · Cited by 362 · see citing works

Poly(ethylenimine)-mediated gene delivery affects endothelial cell function and viability

Godbey, W. T., Wu, K. K., & Mikos, A. G. (2001) · Biomaterials · doi:10.1016/s0142-9612(00)00203-9 · Cited by 361 · see citing works

Manganese ferrite nanoparticle micellar nanocomposites as MRI contrast agent for liver imaging

Lu, J., Shu-li, M., Sun, J., Xia, C., Liu, C., Wang, Z., Zhao, X., Gao, F., Gong, Q., Song, B., et al. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.02.001 · Cited by 356 · see citing works

In vivo imaging of proteolytic enzyme activity using a novel molecular reporter.

Tung, C., Mahmood, U., Bredow, S., et al. (2000) · PubMed · Cited by 350 · see citing works

Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application

Kircheis, R., Wightman, L., Schreiber, A. D., Robitza, B., Roessler, V., Kursa, M., & Wagner, E. (2001) · Gene Therapy · doi:10.1038/sj.gt.3301351 · Cited by 350 · see citing works

Polyethylene glycol-grafted poly-l-lysine as polymeric gene carrier

Choi, Y. H., Liu, F., Kim, J. S., Choi, Y. K., Park, J. S., & Kim, S. W. (1998) · Journal of Controlled Release · doi:10.1016/s0168-3659(97)00174-0 · Cited by 341 · see citing works

Hyaluronic acid modified biodegradable scaffolds for cartilage tissue engineering

Yoo, H. S., Lee, E. A., Yoon, J. J., & Park, T. G. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2004.06.021 · Cited by 320 · see citing works

Doxorubicin‐Loaded Polymeric Micelle Overcomes Multidrug Resistance of Cancer by Double‐Targeting Folate Receptor and Early Endosomal pH

Kim, D., Lee, E. S., Oh, K. T., Gao, Z. G., & Bae, Y. H. (2008) · Small · doi:10.1002/smll.200701275 · Cited by 313 · see citing works

Polyphosphoesters in drug and gene delivery

Zhao, Z., Wang, J., Mao, H., & Leong, K. W. (2003) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(03)00040-1 · Cited by 301 · see citing works

Polysaccharide‐block‐polypeptide Copolymer Vesicles: Towards Synthetic Viral Capsids

Schatz, C., Louguet, S., Meins, J. L., et al. (2009) · Angewandte Chemie International Edition · doi:10.1002/anie.200805895 · Cited by 288 · see citing works

The use of biodegradable polyurethane scaffolds for cartilage tissue engineering: potential and limitations

Grad, S., Kupcsik, L., Górna, K., Gogolewski, S., & Alini, M. (2003) · Biomaterials · doi:10.1016/s0142-9612(03)00462-9 · Cited by 286 · see citing works

New biodegradable polymers for injectable drug delivery systems

Jeong, B., Choi, Y. K., Bae, Y. H., Zentner, G. M., & Kim, S. W. (1999) · Journal of Controlled Release · doi:10.1016/s0168-3659(99)00061-9 · Cited by 285 · see citing works

PEGylated Gold Nanoparticles Conjugated to Monoclonal F19 Antibodies as Targeted Labeling Agents for Human Pancreatic Carcinoma Tissue

Eck, W., Craig, G. A., Sigdel, A., Ritter, G., Old, L. J., Tang, L. H., Brennan, M. F., Allen, P. J., & Mason, M. D. (2008) · ACS Nano · doi:10.1021/nn800429d · Cited by 279 · see citing works

Stabilization of poly-l-lysine/DNA polyplexes for in vivo gene delivery to the liver

Kwoh, D. Y., Coffin, C. C., Lollo, C. P., Jovenal, J., Banaszczyk, M., Mullen, P. M., Phillips, A. T., Amini, A., Fabrycki, J., Bartholomew, R. M., et al. (1999) · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · doi:10.1016/s0167-4781(98)00274-7 · Cited by 276 · see citing works

Synthesis and characterization of electroactive and biodegradable ABA block copolymer of polylactide and aniline pentamer

Huang, L., Hu, J., Lang, L., et al. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2006.12.007 · Cited by 275 · see citing works

PEG conjugated VEGF siRNA for anti-angiogenic gene therapy

Kim, S. H., Jeong, J. H., Lee, S. H., Kim, S. W., & Park, T. G. (2006) · Journal of Controlled Release · doi:10.1016/j.jconrel.2006.05.023 · Cited by 273 · see citing works

Preparation and characterization of thermally responsive block copolymer micelles comprising poly(N-isopropylacrylamide-b-DL-lactide)

Kohori, F., Sakai, K., Aoyagi, T., Yokoyama, M., Sakurai, Y., & Okano, T. (1998) · Journal of Controlled Release · doi:10.1016/s0168-3659(98)00023-6 · Cited by 273 · see citing works

Synthesis of Biodegradable and Electroactive Multiblock Polylactide and Aniline Pentamer Copolymer for Tissue Engineering Applications

Huang, L., Zhuang, X., Hu, J., Lang, L., Zhang, P., Wang, Y., Chen, X., Wei, Y., & Jing, X. (2008) · Biomacromolecules · doi:10.1021/bm7011828 · Cited by 272 · see citing works

In vivo mineralization and osteogenesis of nanocomposite scaffold of poly(lactide-co-glycolide) and hydroxyapatite surface-grafted with poly(l-lactide)

Zhang, P., Hong, Z., Yu, T., Chen, X., & Jing, X. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2008.08.041 · Cited by 268 · see citing works

A polymer library approach to suicide gene therapy for cancer

Anderson, D. G., Peng, W., Akinc, A., Hossain, N., Kohn, A., Padera, R. F., Langer, R., & Sawicki, J. A. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407218101 · Cited by 258 · see citing works

A Novel Biodegradable Gene Carrier Based on Polyphosphoester

Wang, J., Mao, H., & Leong, K. W. (2001) · Journal of the American Chemical Society · doi:10.1021/ja016062m · Cited by 257 · see citing works

Optical Imaging of Matrix Metalloproteinase–2 Activity in Tumors: Feasibility Study in a Mouse Model

Bremer, C., Bredow, S., Mahmood, U., et al. (2001) · Radiology · doi:10.1148/radiol.2212010368 · Cited by 256 · see citing works

Preparation of γ -PGA/chitosan composite tissue engineering matrices

Hsieh, C.-Y., Tsai, S. P., Wang, D.-M., Chang, Y.-N., & Hsieh, H. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.02.012 · Cited by 255 · see citing works

Materials for Peripheral Nerve Regeneration

Ciardelli, G., & Chiono, V. (2005) · Macromolecular Bioscience · doi:10.1002/mabi.200500151 · Cited by 255 · see citing works

Self-assembled biodegradable micellar nanoparticles of amphiphilic and cationic block copolymer for siRNA delivery

Sun, T., Du, J., Yan, L., Mao, H., & Wang, J. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2008.07.036 · Cited by 248 · see citing works

Shell-Detachable Micelles Based on Disulfide-Linked Block Copolymer As Potential Carrier for Intracellular Drug Delivery

Tang, L., Wang, Y., Li, Y., Du, J., & Wang, J. (2009) · Bioconjugate Chemistry · doi:10.1021/bc900144m · Cited by 247 · see citing works

Implanted cardiovascular polymers: Natural, synthetic and bio-inspired

Venkatraman, S. S., Boey, F., & Lao, L. L. (2008) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2008.07.001 · Cited by 246 · see citing works

Target-Specific Cellular Uptake of PLGA Nanoparticles Coated with Poly( l -lysine)−Poly(ethylene glycol)−Folate Conjugate

Kim, S. H., Jeong, J. H., Chun, K. W., & Park, T. G. (2005) · Langmuir · doi:10.1021/la0502084 · Cited by 242 · see citing works

pH-Responsive Biodegradable Micelles Based on Acid-Labile Polycarbonate Hydrophobe: Synthesis and Triggered Drug Release

Chen, W., Meng, F., Li, F., Ji, S., & Zhong, Z. (2009) · Biomacromolecules · doi:10.1021/bm900074d · Cited by 241 · see citing works

Biocompatible Nanofiber Matrices for the Engineering of a Dermal Substitute for Skin Regeneration

Venugopal, J. R., & Ramakrishna, S. (2005) · Tissue Engineering · doi:10.1089/ten.2005.11.847 · Cited by 240 · see citing works

Novel Branched Poly(Ethylenimine)−Cholesterol Water-Soluble Lipopolymers for Gene Delivery

Wang, D., Narang, A. S., Kotb, M., Gaber, A. O., Miller, D. D., Kim, S. W., & Mahato, R. I. (2002) · Biomacromolecules · doi:10.1021/bm025563c · Cited by 237 · see citing works

Cross-linked Small Polyethylenimines: While Still Nontoxic, Deliver DNA Efficiently to Mammalian Cells in Vitro and in Vivo

Thomas, M., Ge, Q., Lu, J. J.-Q., et al. (2005) · Pharmaceutical Research · doi:10.1007/s11095-004-1874-y · Cited by 236 · see citing works

Active targeting with particulate drug carriers in tumor therapy: fundamentals and recent progress

Marcucci, F., & Lefoulon, F. (2004) · Drug Discovery Today · doi:10.1016/s1359-6446(03)02988-x · Cited by 235 · see citing works

Tumor marker-responsive behavior of gels prepared by biomolecular imprinting

Miyata, T., Jige, M., Nakaminami, T., & Uragami, T. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506786103 · Cited by 231 · see citing works

Gene transfer with lipospermines and polyethylenimines

Rémy, J.-S., Abdallah, B., Zanta, M. A., et al. (1998) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(97)00109-9 · Cited by 228 · see citing works

Bulk and surface modifications of polylactide

Wang, S., Cui, W., & Bei, J. (2005) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-004-2771-2 · Cited by 227 · see citing works

Poly-β amino ester-containing microparticles enhance the activity of nonviral genetic vaccines

Little, S. R., Lynn, D. M., Ge, Q., Anderson, D. G., Puram, S. V., Chen, J., Eisen, H. N., & Langer, R. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403549101 · Cited by 227 · see citing works

Reducible Poly(amido ethylenimine)s Designed for Triggered Intracellular Gene Delivery

Christensen, L. V., Chang, C., Kim, W. J., et al. (2006) · Bioconjugate Chemistry · doi:10.1021/bc0602026 · Cited by 224 · see citing works

Polyvinyl Derivatives as Novel Interactive Polymers for Controlled Gene Delivery to Muscle

Mumper, R. J., Duguid, J. G., Anwer, K., Barren, M. K., Nitta, H., & Rolland, A. P. (1996) · Pharmaceutical Research · doi:10.1023/a:1016039330870 · Cited by 223 · see citing works

A Virus‐Mimetic Nanogel Vehicle

Lee, E. S., Kim, D., Youn, Y. S., et al. (2008) · Angewandte Chemie International Edition · doi:10.1002/anie.200704121 · Cited by 215 · see citing works

Controlled preparation and properties of porous poly(l-lactide) obtained from a co-continuous blend of two biodegradable polymers

Sarazin, P., Roy, X., & Favis, B. D. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2004.01.065 · Cited by 210 · see citing works

Bacteriostatic action of a novel four-component bioactive glass

Bellantone, M., Coleman, N. J., & Hench, L. L. (2000) · Journal of Biomedical Materials Research · doi:10.1002/1097-4636(20000905)51:3 · Cited by 209 · see citing works

Biodegradable cationic PEG–PEI–PBLG hyperbranched block copolymer: synthesis and micelle characterization

Tian, H., Deng, C., Lin, H., Sun, J., Deng, M., Chen, X., & Jing, X. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2004.11.002 · Cited by 207 · see citing works

The development of polyanhydrides for drug delivery applications

Tamada, J. A., & Langer, R. (1992) · Journal of Biomaterials Science Polymer Edition · doi:10.1163/156856292x00402 · Cited by 206 · see citing works

Synthesis of Poly(β-amino ester)s with Thiol-Reactive Side Chains for DNA Delivery

Zugates, G. T., Anderson, D. G., Little, S. R., Lawhorn, I. E. B., & Langer, R. (2006) · Journal of the American Chemical Society · doi:10.1021/ja061570n · Cited by 204 · see citing works

Recent progress in polyphosphoesters: From controlled synthesis to biomedical applications

Wang, Y., Yuan, Y., Du, J., Yang, X., & Wang, J. (2009) · Macromolecular Bioscience · doi:10.1002/mabi.200900253 · Cited by 203 · see citing works

PEGylated Polyplex Micelles from Triblock Catiomers with Spatially Ordered Layering of Condensed pDNA and Buffering Units for Enhanced Intracellular Gene Delivery

Fukushima, S., Miyata, K., Nishiyama, N., et al. (2005) · Journal of the American Chemical Society · doi:10.1021/ja0440506 · Cited by 199 · see citing works

Polymers for bioimaging

Kim, J.-H., Park, K., Nam, H. Y., Lee, S., Kim, K., & Kwon, I. C. (2007) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2007.05.016 · Cited by 197 · see citing works

Gene transfection of hyperbranched PEI grafted by hydrophobic amino acid segment PBLG

Tian, H., Xiong, W. H., Wei, J., Wang, Y., Chen, X., Jing, X., & Zhu, Q. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.02.027 · Cited by 193 · see citing works

Biodegradable Polyester, Poly[α-(4-Aminobutyl)-l-Glycolic Acid], as a Non-Toxic Gene Carrier

Lim, Y., Han, S., Kong, H.-U., Lee, Y., Park, J. S., Jeong, B., & Kim, S. W. (2000) · Pharmaceutical Research · doi:10.1023/a:1007552007765 · Cited by 189 · see citing works

Biodegradable and photocrosslinkable polyphosphoester hydrogel

Li, Q., Wang, J., Shahani, S. A., Sun, D. D. N., Sharma, B., Elisseeff, J. H., & Leong, K. W. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.07.019 · Cited by 189 · see citing works

Non-viral vectors in cancer gene therapy: principles and progress

Schätzlein, A. G. (2001) · Anti-Cancer Drugs · doi:10.1097/00001813-200104000-00001 · Cited by 188 · see citing works

Protease sensors for bioimaging

Funovics, M. A., Weissleder, R., & Tung, C. (2003) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-003-2199-0 · Cited by 186 · see citing works

A Self-Destroying Polycationic Polymer: Biodegradable Poly(4-hydroxy- l -proline ester)

Lim, Y., Choi, Y. H., & Park, J. S. (1999) · Journal of the American Chemical Society · doi:10.1021/ja984012k · Cited by 183 · see citing works

Primary Hepatocellular Carcinoma

Wands, J. R., & Blum, H. E. (1991) · New England Journal of Medicine · doi:10.1056/nejm199109053251010 · Cited by 182 · see citing works

Hydrophilic Aliphatic Polyesters: Design, Synthesis, and Ring-Opening Polymerization of Functional Cyclic Esters

Trollsås, M., Lee, V. Y., Mecerreyes, D., Löwenhielm, P., Möller, M., Miller, R. D., & Hedrick, J. L. (2000) · Macromolecules · doi:10.1021/ma992161x · Cited by 181 · see citing works

Polymeric nanomedicine for cancer MR imaging and drug delivery

Khemtong, C., Kessinger, C. W., & Gao, J. (2009) · Chemical Communications · doi:10.1039/b821865j · Cited by 180 · see citing works

Injectable Nanocomposites of Single-Walled Carbon Nanotubes and Biodegradable Polymers for Bone Tissue Engineering

Shi, X. C., Hudson, J. L., Spicer, P. P., Tour, J. M., Krishnamoorti, R., & Mikos, A. G. (2006) · Biomacromolecules · doi:10.1021/bm060391v · Cited by 176 · see citing works

The EPR Effect and Polymeric Drugs: A Paradigm Shift for Cancer Chemotherapy in the 21st Century

Maeda, H., Greish, K. F., & Fang, J. Q. (2005) · Advances in polymer science · doi:10.1007/12_026 · Cited by 173 · see citing works

Ring-opening polymerization of 3(S)-[(benzyloxycarbonyl)methyl]-1,4-dioxane-2,5-dione: a new route to a poly(.alpha.-hydroxy acid) with pendant carboxyl groups

Kimura, Y., Shirotani, K., Yamane, H., & Kitao, T. (1988) · Macromolecules · doi:10.1021/ma00189a037 · Cited by 165 · see citing works

Comparison between cationic polymers and lipids in mediating systemic gene delivery to the lungs

Bragonzi, A., Boletta, A., Biffi, A., Muggia, A., Sersale, G., Cheng, S. H., Bordignon, C., Assael, B. M., & Conese, M. (1999) · Gene Therapy · doi:10.1038/sj.gt.3301039 · Cited by 162 · see citing works

Electrospun Nanofibrous Membranes: A Novel Solid Substrate for Microfluidic Immunoassays for HIV

Yang, D., Niu, X., Liu, Y., et al. (2008) · Advanced Materials · doi:10.1002/adma.200801302 · Cited by 160 · see citing works

Monodispersed Polymeric Nanocapsules: Spontaneous Evolution and Morphology Transition from Reducible Hetero-PEG PICmicelles by Controlled Degradation

Dong, W., Kishimura, A., Anraku, Y., et al. (2009) · Journal of the American Chemical Society · doi:10.1021/ja808419b · Cited by 156 · see citing works

Functional Lactide Monomers: Methodology and Polymerization

Gerhardt, W. W., Noga, D. E., Hardcastle, K. I., Garcı́a, A. J., Collard, D. M., & Weck, M. (2006) · Biomacromolecules · doi:10.1021/bm060024j · Cited by 154 · see citing works

Comparison of in vivo acute stent recoil between the bioabsorbable everolimus‐eluting coronary stent and the everolimus‐eluting cobalt chromium coronary stent: Insights from the ABSORB and SPIRIT trials

Tanimoto, S., Serruys, P. W. J. C., Thuesen, L., et al. (2007) · Catheterization and Cardiovascular Interventions · doi:10.1002/ccd.21136 · Cited by 151 · see citing works

Preparation and characterization of thermally responsive and biodegradable block copolymer comprised of pnipaam and pla by combination of rop and raft methods

You, Y., Hong, C., Wang, W., Lu, W., & Pan, C. (2004) · Macromolecules · doi:10.1021/ma048444t · Cited by 151 · see citing works

Polyacetal−Doxorubicin Conjugates Designed for pH-Dependent Degradation

Tomlinson, R. D., Heller, J., Brocchini, S., & Duncan, R. (2003) · Bioconjugate Chemistry · doi:10.1021/bc030028a · Cited by 151 · see citing works

Activatable imaging probes with amplified fluorescent signals

Lee, S., Park, K., Kim, K., et al. (2008) · Chemical Communications · doi:10.1039/b806854m · Cited by 150 · see citing works

Targeted delivery of plasmid DNA complexed with galactosylated poly(l-lysine)

Hashida, M., Takemura, S., Nishikawa, M., & Takakura, Y. (1998) · Journal of Controlled Release · doi:10.1016/s0168-3659(97)00263-0 · Cited by 150 · see citing works

pH-Responsive Oligodeoxynucleotide (ODN)−Poly(Ethylene Glycol) Conjugate through Acid-Labile β-Thiopropionate Linkage: Preparation and Polyion Complex Micelle Formation

Oishi, M., Sasaki, S., Nagasaki, Y., et al. (2003) · Biomacromolecules · doi:10.1021/bm034164u · Cited by 148 · see citing works

Self-assembled lamellar complexes of siRNA with lipidic aminoglycoside derivatives promote efficient siRNA delivery and interference

Desigaux, L., Sainlos, M., Lambert, O., Chèvre, R., Letrou-Bonneval, E., Vigneron, J., Lehn, P., Lehn, J., & Pitard, B. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0707431104 · Cited by 146 · see citing works

Functionalized micelles from block copolymer of polyphosphoester and poly(ɛ-caprolactone) for receptor-mediated drug delivery

Wang, Y., Liu, X., Sun, T., Xiong, M., & Wang, J. (2008) · Journal of Controlled Release · doi:10.1016/j.jconrel.2008.01.021 · Cited by 145 · see citing works

Novel Functional Polycarbonate by Lipase-Catalyzed Ring-Opening Polymerization of 5-Methyl-5-benzyloxycarbonyl-1,3-dioxan-2-one

Al‐Azemi, T. F., & Bisht, K. S. (1999) · Macromolecules · doi:10.1021/ma990639r · Cited by 142 · see citing works

Synthesis of Novel Biodegradable Thermoresponsive Triblock Copolymers Based on Poly[(R)-3-hydroxybutyrate] and Poly(N-isopropylacrylamide) and Their Formation of Thermoresponsive Micelles

Loh, X. J., Zhang, Z., Wu, Y., Lee, T. S., & Li, J. (2008) · Macromolecules · doi:10.1021/ma8019865 · Cited by 141 · see citing works

Degradation of Poly(L-lactide) by a Fungus

Jarerat, A., & Tokiwa, Y. (2001) · Macromolecular Bioscience · doi:10.1002/1616-5195(20010601)1:4 · Cited by 141 · see citing works

Thermoresponsive Block Copolymers of Poly(ethylene glycol) and Polyphosphoester: Thermo-Induced Self-Assembly, Biocompatibility, and Hydrolytic Degradation

Wang, Y., Tang, L., Li, Y., & Wang, J. (2008) · Biomacromolecules · doi:10.1021/bm800808q · Cited by 140 · see citing works

Ring-Opening Polymerization of 1,4,8-Trioxaspiro[4.6]-9-undecanone: A New Route to Aliphatic Polyesters Bearing Functional Pendent Groups

Tian, D., Dubois, P., Grandfils, C., & Jérôme, R. (1997) · Macromolecules · doi:10.1021/ma961631+ · Cited by 140 · see citing works

Polyplex Micelles with Cyclic RGD Peptide Ligands and Disulfide Cross-Links Directing to the Enhanced Transfection via Controlled Intracellular Trafficking

Oba, M., Aoyagi, K., Miyata, K., Matsumoto, Y., Itaka, K., Nishiyama, N., Yamasaki, Y., Koyama, H., & Kataoka, K. (2008) · Molecular Pharmaceutics · doi:10.1021/mp800070s · Cited by 140 · see citing works

Macrocyclic Esters¹

Spanagel, E. W., & Carothers, W. H. (1935) · Journal of the American Chemical Society · doi:10.1021/ja01308a046 · Cited by 139 · see citing works

Transfection of Folate-Polylysine DNA Complexes: Evidence for Lysosomal Delivery

Mislick, K. A., Baldeschwieler, J. D., Kayyem, J. F., et al. (1995) · Bioconjugate Chemistry · doi:10.1021/bc00035a002 · Cited by 139 · see citing works

Methylated Mono- and Diethyleneglycol Functionalized Polylysines: Nonionic, α-Helical, Water-Soluble Polypeptides

Yu, M., Nowak, A. P., Deming, T. J., et al. (1999) · Journal of the American Chemical Society · doi:10.1021/ja993637v · Cited by 137 · see citing works

Cellular recognition of paclitaxel-loaded polymeric nanoparticles composed of poly(γ-benzyl l-glutamate) and poly(ethylene glycol) diblock copolymer endcapped with galactose moiety

JEONG, Y., SEO, S., Park, I., Lee, H., Kang, I., Akaike, T., & CHO, C. (2005) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2005.02.027 · Cited by 136 · see citing works

Tailoring Biomaterial Compatibility: In Vivo Tissue Response versus in Vitro Cell Behavior

Mattioli‐Belmonte, M., Giavaresi, G., Biagini, G., et al. (2003) · The International Journal of Artificial Organs · doi:10.1177/039139880302601205 · Cited by 136 · see citing works

Unimolecular Combination of an Atom Transfer Radical Polymerization Initiator and a Lactone Monomer as a Route to New Graft Copolymers

Mecerreyes, D., Atthoff, B., Boduch, K. A., Trollsås, M., & Hedrick, J. L. (1999) · Macromolecules · doi:10.1021/ma982005a · Cited by 135 · see citing works

Optically active poly (\-malic-acid)

Guérin, P., Vert, M., Braud, C., & Lenz, R. W. (1985) · Polymer Bulletin · doi:10.1007/bf00708479 · Cited by 135 · see citing works

Synthesis and Characterization of RGD Peptide Grafted Poly(ethylene glycol)-b-Poly( l -lactide)-b-Poly( l -glutamic acid) Triblock Copolymer

Deng, C., Tian, H., Zhang, P., et al. (2006) · Biomacromolecules · doi:10.1021/bm050678c · Cited by 134 · see citing works

Surface modification of bioactive glass nanoparticles and the mechanical and biological properties of poly(l-lactide) composites

Liu, A., Hong, Z., Zhuang, X., Chen, X., Cui, Y., Liu, Y., & Jing, X. (2008) · Acta Biomaterialia · doi:10.1016/j.actbio.2008.02.013 · Cited by 133 · see citing works

Transfection Activity of Polyamidoamine Dendrimers Having Hydrophobic Amino Acid Residues in the Periphery

Kono, K., Akiyama, H., Takahashi, T., et al. (2004) · Bioconjugate Chemistry · doi:10.1021/bc049785e · Cited by 133 · see citing works

Genetically engineered polymers: status and prospects for controlled release

Haider, M. A., Megeed, Z., & Ghandehari, H. (2004) · Journal of Controlled Release · doi:10.1016/j.jconrel.2003.11.011 · Cited by 132 · see citing works

Novel Aliphatic Polyesters Based on Functional Cyclic (Di)Esters

Lou, X., Detrembleur, C., & Jérôme, R. (2003) · Macromolecular Rapid Communications · doi:10.1002/marc.200390029 · Cited by 132 · see citing works

Polyurethane/poly(lactic-co-glycolic) acid composite scaffolds fabricated by thermally induced phase separation

Rowlands, A., Lim, S., Martin, D. J., & Cooper-White, J. J. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2006.12.032 · Cited by 131 · see citing works

Development of hybrid polymer scaffolds for potential applications in ligament and tendon tissue engineering

Sahoo, S., Cho-Hong, J. G., & Toh, S. (2007) · Biomedical Materials · doi:10.1088/1748-6041/2/3/001 · Cited by 129 · see citing works

In Vitro and in Vivo Release of Albumin Using a Biodegradable MPEG-PCL Diblock Copolymer as an in Situ Gel-Forming Carrier

Hyun, H., Kim, Y. H., Song, I. B., Lee, J. W., Kim, M. S., Khang, G., Park, K., & Lee, H. B. (2007) · Biomacromolecules · doi:10.1021/bm060991u · Cited by 128 · see citing works

Heart valve tissue engineering

Neuenschwander, S. M., & Hoerstrup, S. P. (2004) · Transplant Immunology · doi:10.1016/j.trim.2003.12.010 · Cited by 128 · see citing works

Synthesis and Characterization of Thermo- and pH-Responsive Double-Hydrophilic Diblock Copolypeptides

Zhang, X., Li, J., Li, W., et al. (2007) · Biomacromolecules · doi:10.1021/bm700729t · Cited by 128 · see citing works

Antibody Targeting of Camptothecin-Loaded PLGA Nanoparticles to Tumor Cells

McCarron, P. A., Marouf, W. M., Quinn, D. J., Fay, F., Burden, R. E., Olwill, S. A., & Scott, C. J. (2008) · Bioconjugate Chemistry · doi:10.1021/bc800057g · Cited by 127 · see citing works

Randomized Phase III Trial Comparing Single-Agent Paclitaxel Poliglumex (CT-2103, PPX) with Single-Agent Gemcitabine or Vinorelbine for the Treatment of PS 2 Patients with Chemotherapy-Naïve Advanced Non-small Cell Lung Cancer

O'Brien, M. E. R., Socinski, M. A., Popovich, A. Y., Bondarenko, I., Tomova, A., ̆ı, B. T. B., Hotko, Y., Ganul, V. L., Kostinsky, I. Y., Eisenfeld, A. J., et al. (2008) · Journal of Thoracic Oncology · doi:10.1097/jto.0b013e31817c6b68 · Cited by 125 · see citing works

Intracellular siRNA delivery system using polyelectrolyte complex micelles prepared from VEGF siRNA-PEG conjugate and cationic fusogenic peptide

Lee, S. H., Kim, S. H., & Park, T. G. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.03.185 · Cited by 124 · see citing works

Tissue Reaction to Polypyrrole-Coated Polyester Fabrics: An in Vivo Study in Rats

Jiang, X., Marois, Y., Traoré, A. S., Tessier, D., Dao, L. H., Guidoin, R., & Zhang, Z. (2002) · Tissue Engineering · doi:10.1089/107632702760240553 · Cited by 124 · see citing works

New polyphosphoramidate with a spermidine side chain as a gene carrier

Wang, J., Zhang, P., Lu, H.-F., Ma, N., Wang, S., Mao, H., & Leong, K. W. (2002) · Journal of Controlled Release · doi:10.1016/s0168-3659(02)00180-3 · Cited by 123 · see citing works

Polypyrrole Thin Films Formed by Admicellar Polymerization Support the Osteogenic Differentiation of Mesenchymal Stem Cells

Castano‐Izquierdo, H., O’Rear, E. A., McFetridge, P. S., & Sikavitsas, V. I. (2004) · Macromolecular Bioscience · doi:10.1002/mabi.200300123 · Cited by 121 · see citing works

Physicochemical properties and nuclease resistance of antisense-oligodeoxynucleotides entrapped in the core of polyion complex micelles composed of poly(ethylene glycol)–poly(l-Lysine) block copolymers

Harada, A., Togawa, H., & Kataoka, K. (2001) · European Journal of Pharmaceutical Sciences · doi:10.1016/s0928-0987(00)00205-0 · Cited by 121 · see citing works

Nitrilotriacetic Acid Functionalized Graft Copolymers: A Polymeric Interface for Selective and Reversible Binding of Histidine‐Tagged Proteins

Zhen, G., Falconnet, D., Kuennemann, E., et al. (2005) · Advanced Functional Materials · doi:10.1002/adfm.200500232 · Cited by 121 · see citing works

Novel Thermoresponsive Polymers Having Biodegradable Phosphoester Backbones

Iwasaki, Y., Wachiralarpphaithoon, C., & Akiyoshi, K. (2007) · Macromolecules · doi:10.1021/ma0715573 · Cited by 120 · see citing works

Electroactive Oligoaniline-Containing Self-Assembled Monolayers for Tissue Engineering Applications

Guo, Y., Li, M., Mylonakis, A., et al. (2007) · Biomacromolecules · doi:10.1021/bm070266z · Cited by 118 · see citing works

Water-soluble biodegradable cationic polyphosphazenes for gene delivery

Luten, J., van Steenis, J. H., van Someren, R., et al. (2003) · Journal of Controlled Release · doi:10.1016/s0168-3659(03)00127-5 · Cited by 116 · see citing works

Biodegradable Poly(ethylene glycol)-co-poly( l -lysine)-g-histidine Multiblock Copolymers for Nonviral Gene Delivery

Bikram, M., Ahn, C.-H., Chae, S. Y., Lee, M., Yockman, J. W., & Kim, S. W. (2004) · Macromolecules · doi:10.1021/ma035650c · Cited by 116 · see citing works

The immobilization of proteins on biodegradable polymer fibers via click chemistry

Shi, Q., Chen, X., Lu, T., & Jing, X. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.11.008 · Cited by 115 · see citing works

Biodegradable scleral plugs for vitreoretinal drug delivery

Yasukawa, T., Kimura, H., Tabata, Y., et al. (2001) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(01)00192-2 · Cited by 114 · see citing works

Poly(aspartate-g-PEI800), a polyethylenimine analogue of low toxicity and high transfection efficiency for gene delivery

Xiong, M. P., Forrest, M. L., Ton, G. N., Zhao, A., Davies, N. M., & Kwon, G. S. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.07.043 · Cited by 114 · see citing works

Rational design of light‐controllable polymer micelles

Zhao, Y. (2007) · The Chemical Record · doi:10.1002/tcr.20127 · Cited by 113 · see citing works

Enzyme-degradable phosphorylcholine porous hydrogels cross-linked with polyphosphoesters for cell matrices

Wachiralarpphaithoon, C., Iwasaki, Y., & Akiyoshi, K. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.10.024 · Cited by 111 · see citing works

The future of drug-eluting stents

Kukreja, N., Onuma, Y., Daemen, J., et al. (2008) · Pharmacological Research · doi:10.1016/j.phrs.2008.01.012 · Cited by 109 · see citing works

Direct Formation of Giant Vesicles from Synthetic Polypeptides

Sun, J., Chen, X., Deng, C., Yu, H., Xie, Z., & Jing, X. (2007) · Langmuir · doi:10.1021/la701038f · Cited by 109 · see citing works

Synthesis of poly(α‐malic acid) and its hydrolysis behavior in vitro

Ouchi, T., & Fujino, A. (1989) · Die Makromolekulare Chemie · doi:10.1002/macp.1989.021900703 · Cited by 109 · see citing works

Kinetics and Mechanism of 2-Ethoxy-2-oxo-1,3,2-dioxaphospholane Polymerization Initiated by Stannous Octoate

Xiao, C., Wang, Y., Du, J., Chen, X., & Wang, J. (2006) · Macromolecules · doi:10.1021/ma0615396 · Cited by 106 · see citing works

Poly(lactide-co-glycolide) microspheres as a moldable scaffold for cartilage tissue engineering

Mercier, N. R., Costantino, H. R., Tracy, M. A., & Bonassar, L. J. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2004.06.030 · Cited by 106 · see citing works

A comparison of the effectiveness of cationic polymers poly-l-lysine (PLL) and polyethylenimine (PEI) for non-viral delivery of plasmid DNA to bone marrow stromal cells (BMSC)

Farrell, L.-L., Pepin, J., Kucharski, C., et al. (2006) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2006.11.026 · Cited by 106 · see citing works

pH‐induced Micelle Formation of Poly(histidine‐co‐phenylalanine)‐block‐Poly(ethylene glycol) in Aqueous Media

Kim, G. M., Bae, Y. H., & Jo, W. H. (2005) · Macromolecular Bioscience · doi:10.1002/mabi.200500121 · Cited by 106 · see citing works

Microparticles and Nanoparticles as Delivery Systems for DNA Vaccines

Cui, Z., & Mumper, R. J. (2003) · Critical Reviews in Therapeutic Drug Carrier Systems · doi:10.1615/critrevtherdrugcarriersyst.v20.i23.10 · Cited by 105 · see citing works

Tunable Thermosensitivity of Biodegradable Polymer Micelles of Poly(ε-caprolactone) and Polyphosphoester Block Copolymers

Wang, Y., Li, Y., Yang, X., Yuan, Y., Yan, L., & Wang, J. (2009) · Macromolecules · doi:10.1021/ma900288t · Cited by 105 · see citing works

Normal Bone Anatomy and Physiology

Clarke, B. (2008) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.04151206 · Cited by 2,192 · see citing works

Smart nanoparticles for cancer therapy

Sun, L., Liu, H., Ye, Y., Lei, Y., Islam, R., Tan, S., Tong, R., Miao, Y.-B., & Cai, L. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01642-x · Cited by 1,073 · see citing works

Biodegradable and biocompatible polymers for tissue engineering application: A review

Asghari, F., Samiei, M., Adibkia, K., Akbarzadeh, A., & Davaran, S. (2017) · Artificial Cells, Nanomedicine, and Biotechnology · doi:10.3109/21691401.2016.1146731 · Cited by 482 · see citing works

Crystallization of biodegradable and biobased polyesters: Polymorphism, cocrystallization, and structure-property relationship

Zheng, Y., & Pan, P. (2020) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2020.101291 · Cited by 229 · see citing works

Main-chain poly(phosphoester)s: History, syntheses, degradation, bio-and flame-retardant applications

Bauer, K. N., Tee, H. T., Velencoso, M. M., & Wurm, F. R. (2017) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2017.05.004 · Cited by 189 · see citing works

Biocompatibility of Resorbable Polymers: A Historical Perspective and Framework for the Future

Pappalardo, D., Mathisen, T., & Finne-Wistrand, A. (2019) · Biomacromolecules · doi:10.1021/acs.biomac.9b00159 · Cited by 177 · see citing works

Synthesis, Characterization, Functionalization and Bio-Applications of Hydroxyapatite Nanomaterials: An Overview

Munir, M. U., Salman, S., Ihsan, A., & Elsaman, T. (2022) · International Journal of Nanomedicine · doi:10.2147/ijn.s360670 · Cited by 132 · see citing works

A Simple and Facile Approach to Aliphatic <i>N</i>-Substituted Functional Eight-Membered Cyclic Carbonates and Their Organocatalytic Polymerization

Venkataraman, S., Ng, V. W. L., Coady, D. J., Horn, H. W., Jones, G. O., Fung, T. S., Sardon, H., Waymouth, R. M., Hedrick, J. L., & Yang, Y. Y. (2015) · Journal of the American Chemical Society · doi:10.1021/jacs.5b06355 · Cited by 97 · see citing works

Redox Switchable Copolymerization of Cyclic Esters and Epoxides by a Zirconium Complex

Quan, S. M., Wang, X., Zhang, R., & Diaconescu, P. L. (2016) · Macromolecules · doi:10.1021/acs.macromol.6b00997 · Cited by 93 · see citing works

Coordination ring-opening polymerization of cyclic esters: A critical overview of DFT modeling and visualization of the reaction mechanisms

Nifant’ev, I., & Ivchenko, P. (2019) · Molecules · doi:10.3390/molecules24224117 · Cited by 72 · see citing works

Polyphosphoesters: New trends in synthesis and drug delivery applications

Yilmaz, Z. E., & Jérôme, C. (2016) · Macromolecular Bioscience · doi:10.1002/mabi.201600269 · Cited by 71 · see citing works

Mono-BHT heteroleptic magnesium complexes: Synthesis, molecular structure and catalytic behavior in the ring-opening polymerization of cyclic esters

Nifant'ev, I. E., Shlyakhtin, A. V., Bagrov, V. V., Minyaev, M. E., Churakov, A. V., Karchevsky, S. G., Birin, K. P., & Ivchenko, P. V. (2017) · Dalton Transactions · doi:10.1039/c7dt02469j · Cited by 62 · see citing works

Synthesis and molecular characterization of chitosan/starch blends based polyurethanes

Javaid, M. A., Zia, K. M., Zafar, K., Khosa, M. K., Akram, N., Ajmal, M., Imran, M., & Iqbal, M. N. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.12.234 · Cited by 54 · see citing works

Design, Degradation Mechanism and Long‐Term Cytotoxicity of Poly(<scp>l</scp>‐lactide) and Poly(Lactide‐co‐ϵ‐Caprolactone) Terpolymer Film and Air‐Spun Nanofiber Scaffold

Sabbatier, G., Larrañaga, A., Guay‐Bégin, A., Fernandez, J., Diéval, F., Durand, B., Sarasua, J., & Laroche, G. (2015) · Macromolecular Bioscience · doi:10.1002/mabi.201500130 · Cited by 32 · see citing works

Treatment of Bone Defects and Nonunion via Novel Delivery Mechanisms, Growth Factors, and Stem Cells: A Review

Ehlen, Q. T., Costello, J. P., Mirsky, N. A., Slavin, B. V., Parra, M., Ptashnik, A., Nayak, V. V., Coelho, P. G., & Witek, L. (2024) · ACS Biomaterials Science &amp; Engineering · doi:10.1021/acsbiomaterials.4c01279 · Cited by 29 · see citing works

Exploring Oxidation State-Dependent Selectivity in Polymerization of Cyclic Esters and Carbonates with Zinc(II) Complexes

Abubekerov, M., Vlček, V., Wei, J., Miehlich, M. E., Quan, S. M., Meyer, K., Neuhauser, D., & Diaconescu, P. L. (2018) · iScience · doi:10.1016/j.isci.2018.08.020 · Cited by 26 · see citing works

Preparation and shape memory properties of TiO2/PLCL biodegradable polymer nanocomposites

LU, X.-L., LÜ, X.-Q., WANG, J.-Y., SUN, Z.-J., & TONG, Y.-X. (2013) · Transactions of Nonferrous Metals Society of China · doi:10.1016/s1003-6326(13)62437-1 · Cited by 18 · see citing works

Biodegradable polymers and environmental interaction

Karlsson, S., & Albertsson, A. (1998) · Polymer Engineering and Science · doi:10.1002/pen.10294 · Cited by 167 · see citing works

The Effect of the Nature of Biodegradable Components on Biodegradability of Composites Based on Polyethylene

Varyan, I. A., Podzorova, M. V., Tertyshnaya, Y. V., Kolesnikova, N. N., & Попов, А. А. (2023) · Polymer Science Series D · doi:10.1134/s1995421223020466 · Cited by 1 · see citing works

Nano-biodegradation of polymers

Rızwan, K., Rasheed, T., & Bilal, M. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-823970-4.00010-5 · Cited by 19 · see citing works

Biodegradable plastics and polymers : proceedings of the Third International Scientific Workshop on Biodegradable Plastics and Polymers, Osaka, Japan, November 9-11, 1993

土肥, 義., & Fukuda, K. (1994) · Elsevier eBooks · Cited by 5 · see citing works

Biodegradable Plastics from Renewable Resources

Demirbaş, A. O. (2007) · Energy Sources Part A Recovery Utilization and Environmental Effects · doi:10.1080/009083190965820 · Cited by 80 · see citing works