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Mannose‐Functionalized Mesoporous Silica Nanoparticles for Efficient Two‐Photon Photodynamic Therapy of Solid Tumors
Abstract
Zap 'em! Multifunctionalized mesoporous silica nanoparticles induce significant reduction of tumor size upon two-photon excitation in the near-infrared region while being nontoxic under daylight illumination. These nanoparticles were further tested for in vivo two-photon photodynamic therapy (TPE-PDT). A 70 % regression of tumor size after a single treatment was observed in athymic mice bearing tumor xenografts.
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Citations
Cited by
Recent Strategies to Develop Innovative Photosensitizers for Enhanced Photodynamic Therapy
Pham, T. C., Nguyen, V.-N., Choi, Y., Lee, S., & Yoon, J. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00381 · Cited by 1,813
Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems
Karimi, M., Ghasemi, A., Sahandi Zangabad, P., Rahighi, R., Moosavi Basri, S. M., Mirshekari, H., Amiri, M., Shafaei Pishabad, Z., Aslani, A., Bozorgomid, M., et al. (2016) · Chemical Society Reviews · doi:10.1039/c5cs00798d · Cited by 1,519
Gu, B., Wu, W., Xu, G., Feng, G., Yin, F., Chong, P. H. J., Qu, J., Yong, K., & Liu, B. (2017) · Advanced Materials · doi:10.1002/adma.201701076 · Cited by 308
Development of Mesoporous Silica Nanomaterials As a Vehicle for Anticancer Drug Delivery
Yanes, R. E., & Tamanoi, F. (2012) · Therapeutic Delivery · doi:10.4155/tde.12.9 · Cited by 68
Metadata
- Authors
- Gary‐Bobo, M., Mir, Y., Rouxel, C., Brevet, D., Basile, I., Maynadier, M., Vaillant, O., Mongin, O., Blanchard‐Desce, M., Morère, A., Garcia, M., Durand, J., & Raehm, L.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2011-10-04
- Volume
- 50
- Issue
- 48
- Pages
- 11425-11429
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2102074283
- Cited by
- 261
- References
- 0
- FWCI
- 12.95
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Mannose‐Functionalized Mesoporous Silica Nanoparticles for Efficient Two‐Photon Photodynamic Therapy of Solid Tumors. https://app.cochat.ai/papers/10.1002/anie.201104765
- The paper
- Gary‐Bobo, M., Mir, Y., Rouxel, C., Brevet, D., Basile, I., Maynadier, M., Vaillant, O., Mongin, O., Blanchard‐Desce, M., Morère, A., Garcia, M., Durand, J., & Raehm, L. (2011). Mannose‐Functionalized Mesoporous Silica Nanoparticles for Efficient Two‐Photon Photodynamic Therapy of Solid Tumors. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.201104765
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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