The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Light‐Controlled Tools
Abstract
Spatial and temporal control over chemical and biological processes plays a key role in life, where the whole is often much more than the sum of its parts. Quite trivially, the molecules of a cell do not form a living system if they are only arranged in a random fashion. If we want to understand these relationships and especially the problems arising from malfunction, tools are necessary that allow us to design sophisticated experiments that address these questions. Highly valuable in this respect are external triggers that enable us to precisely determine where, when, and to what extent a process is started or stopped. Light is an ideal external trigger: It is highly selective and if applied correctly also harmless. It can be generated and manipulated with well‐established techniques, and many ways exist to apply light to living systems—from cells to higher organisms. This Review will focus on developments over the last six years and includes discussions on the underlying technologies as well as their applications.
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Cites
The development and application of optogenetics
Fenno, L., Yizhar, O., & Deisseroth, K. (2011) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-061010-113817 · Cited by 1,822
Adding New Chemistries to the Genetic Code
Liu, C. C., & Schultz, P. G. (2010) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.052308.105824 · Cited by 1,725
Shankar, G. M., Bloodgood, B. L., Townsend, M., Walsh, D. M., Selkoe, D. J., & Sabatini, B. L. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.4970-06.2007 · Cited by 1,592
Matsuzaki, M., Ellis-Davies, G. C. R., Nemoto, T., Miyashita, Y., Iino, M., & Kasai, H. (2001) · Nature Neuroscience · doi:10.1038/nn736 · Cited by 1,563
Channelrhodopsin-2-assisted circuit mapping of long-range callosal projections
Petreanu, L., Huber, D., Sobczyk, A., & Svoboda, K. (2007) · Nature Neuroscience · doi:10.1038/nn1891 · Cited by 930
Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation
McGinty, R. K., Kim, J., Chatterjee, C., Roeder, R. G., & Muir, T. W. (2008) · Nature · doi:10.1038/nature06906 · Cited by 563
Surface Mobility of Postsynaptic AMPARs Tunes Synaptic Transmission
Heine, M., Groc, L., Frischknecht, R., Béïque, J.-C., Lounis, B., Rumbaugh, G., Huganir, R. L., Cognet, L., & Choquet, D. (2008) · Science · doi:10.1126/science.1152089 · Cited by 518
An optogenetic toolbox designed for primates
Diester, I., Kaufman, M. T., Mogri, M., Pashaie, R., Goo, W., Yizhar, O., Ramakrishnan, C., Deisseroth, K., & Shenoy, K. V. (2011) · Nature Neuroscience · doi:10.1038/nn.2749 · Cited by 443
Optical induction of plasticity at single synapses reveals input-specific accumulation of αCaMKII
Zhang, Y.-P., Holbro, N., & Oertner, T. G. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0802940105 · Cited by 140
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Metadata
- Authors
- Brieke, C., Rohrbach, F., Gottschalk, A., Mayer, G., & Heckel, A.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2012-07-24
- Volume
- 51
- Issue
- 34
- Pages
- 8446-8476
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2136698583
- Cited by
- 955
- References
- 9
- FWCI
- 35.91
- Type
- journal article
- Language
- en
- Open access
- closed
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