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Cited by 599

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End‐to‐End Continuous Manufacturing of Pharmaceuticals: Integrated Synthesis, Purification, and Final Dosage Formation

Open access
Mascia, Salvatore, Heider, Patrick L., Zhang, Haitao, Lakerveld, Richard, Benyahia, Brahim, Barton, Paul I., Braatz, Richard D., Cooney, Charles L., Evans, James M. B., Jamison, Timothy F., Jensen, Klavs F., Myerson, Allan S., Trout, Bernhardt L.·2013·Angewandte Chemie International Edition
DOI 10.1002/anie.201305429
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Abstract

A series of tubes: The continuous manufacture of a finished drug product starting from chemical intermediates is reported. The continuous pilot-scale plant used a novel route that incorporated many advantages of continuous-flow processes to produce active pharmaceutical ingredients and the drug product in one integrated system.

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Metadata

Authors
Mascia, S., Heider, P. L., Zhang, H., Lakerveld, R., Benyahia, B., Barton, P. I., Braatz, R. D., Cooney, C. L., Evans, J. M. B., Jamison, T. F., Jensen, K. F., Myerson, A. S., & Trout, B. L.
Venue
Angewandte Chemie International Edition
Publisher
Wiley
Published
2013-10-02
Volume
52
Issue
47
Pages
12359-12363
ISSN
  • 1433-7851 (ISSN-L)
  • 1521-3773
DOI
10.1002/anie.201305429
OpenAlex
W2112211764
Cited by
599
References
0
FWCI
24.80
Type
journal article
Language
en
Open access
green
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)

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CoChat. (2026). Citation check: End‐to‐End Continuous Manufacturing of Pharmaceuticals: Integrated Synthesis, Purification, and Final Dosage Formation. https://app.cochat.ai/papers/10.1002/anie.201305429
The paper
Mascia, S., Heider, P. L., Zhang, H., Lakerveld, R., Benyahia, B., Barton, P. I., Braatz, R. D., Cooney, C. L., Evans, J. M. B., Jamison, T. F., Jensen, K. F., Myerson, A. S., & Trout, B. L. (2013). End‐to‐End Continuous Manufacturing of Pharmaceuticals: Integrated Synthesis, Purification, and Final Dosage Formation. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.201305429

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.