The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Reading Polymers: Sequencing of Natural and Synthetic Macromolecules
Abstract
The sequencing of biopolymers such as proteins and DNA is among the most significant scientific achievements of the 20th century. Indeed, modern chemical methods for sequence analysis allow reading and understanding the codes of life. Thus, sequencing methods currently play a major role in applications as diverse as genomics, gene therapy, biotechnology, and data storage. However, in terms of fundamental science, sequencing is not really a question of molecular biology but rather a more general topic in macromolecular chemistry. Broadly speaking, it can be defined as the analysis of comonomer sequences in copolymers. However, relatively different approaches have been used in the past to study monomer sequences in biological and manmade polymers. Yet, these “cultural” differences are slowly fading away with the recent development of synthetic sequence‐controlled polymers. In this context, the aim of this Minireview is to present an overview of the tools that are currently available for sequence analysis in macromolecular science.
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Cites
A rapid method for determining sequences in DNA by primed synthesis with DNA polymerase
Sanger, F., & Coulson, A. R. (1975) · Journal of Molecular Biology · doi:10.1016/0022-2836(75)90213-2 · Cited by 2,709
Sanger, F., & Tuppy, H. (1951) · Biochemical Journal · doi:10.1042/bj0490481 · Cited by 505
Cited by
Design and synthesis of digitally encoded polymers that can be decoded and erased
Roy, R. K., Meszynska, A., Laure, C., Charles, L., Verchin, C., & Lutz, J.-F. (2015) · Nature Communications · doi:10.1038/ncomms8237 · Cited by 308
Self-citationFabrication of Bioinspired Hydrogels: Challenges and Opportunities
Fan, H., & Gong, J. P. (2020) · Macromolecules · doi:10.1021/acs.macromol.0c00238 · Cited by 292
Chemoselective Polymerizations from Mixtures of Epoxide, Lactone, Anhydride, and Carbon Dioxide
Romain, C., Zhu, Y., Dingwall, P., Paul, S., Rzepa, H. S., Buchard, A., & Williams, C. K. (2016) · Journal of the American Chemical Society · doi:10.1021/jacs.5b13070 · Cited by 258
Encoding information into polymers
Rutten, M. G. T. A., Vaandrager, F. W., Elemans, J. A. A. W., & Nolte, R. J. M. (2018) · Nature Reviews Chemistry · doi:10.1038/s41570-018-0051-5 · Cited by 216
Aerolysin nanopores decode digital information stored in tailored macromolecular analytes
Cao, C., Krapp, L. F., Al Ouahabi, A., König, N. F., Cirauqui, N., Radenovic, A., Lutz, J.-F., & Peraro, M. D. (2020) · Science Advances · doi:10.1126/sciadv.abc2661 · Cited by 97
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Metadata
- Authors
- Mutlu, H., & Lutz, J.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2014-10-03
- Volume
- 53
- Issue
- 48
- Pages
- 13010-13019
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2145530039
- Cited by
- 177
- References
- 2
- FWCI
- 8.53
- Type
- journal article
- Language
- en
- Open access
- closed
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