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Cited by 348

The DOI matches its Crossref record; 103 of the 103 references it cites were found in a registry or an index.

Hybrid Rhodamine Fluorophores in the Visible/NIR Region for Biological Imaging

Wang, Liulin, Du, Wei, Hu, Zhangjun, Uvdal, Kajsa, Li, Lin, Huang, Wei·2019·Angewandte Chemie International Edition

Abstract

Fluorophores and probes are invaluable for the visualization of the location and dynamics of gene expression, protein expression, and molecular interactions in complex living systems. Rhodamine dyes are often used as scaffolds in biological labeling and turn‐on fluorescence imaging. To date, their absorption and emission spectra have been expanded to cover the entire near‐infrared region (650–950 nm), which provides a more suitable optical window for monitoring biomolecular production, trafficking, and localization in real time. This review summarizes the development of rhodamine fluorophores since their discovery and provides strategies for modulating their absorption and emission spectra to generate specific bathochromic‐shifts. We also explain how larger Stokes shifts and dual‐emissions can be obtained from hybrid rhodamine dyes. These hybrid fluorophores can be classified into various categories based on structural features including the alkylation of amidogens, the substitution of the O atom of xanthene, and hybridization with other fluorophores.

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Metadata

Authors
Wang, L., Du, W., Hu, Z., Uvdal, K., Li, L., & Huang, W.
Venue
Angewandte Chemie International Edition
Publisher
Wiley
Published
2019-06-11
Volume
58
Issue
40
Pages
14026-14043
ISSN
  • 1433-7851 (ISSN-L)
  • 1521-3773
OpenAlex
W2921220156
Cited by
348
References
103
FWCI
15.65
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Hybrid Rhodamine Fluorophores in the Visible/NIR Region for Biological Imaging. https://app.cochat.ai/papers/10.1002/anie.201901061
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Wang, L., Du, W., Hu, Z., Uvdal, K., Li, L., & Huang, W. (2019). Hybrid Rhodamine Fluorophores in the Visible/NIR Region for Biological Imaging. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.201901061

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