The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
A randomized, double‐blind crossover trial of fluoxetine and amitriptyline in the treatment of fibromyalgia
Abstract
Objective. To study the effect of fluoxetine (FL) and amitriptyline (AM), alone and in combination, in patients with fibromyalgia (FM). Methods. Nineteen patients with FM completed a randomized, double‐blind crossover study, which consisted of 4 6‐week trials of FL (20 mg), AM (25 mg), a combination of FL and AM, or placebo. Patients were evaluated on the first and last day of each trial period. Outcome measures included a tender point score, the Fibromyalgia Impact Questionnaire (FIQ), the Beck Depression Inventory (BDI) scale, and visual analog scales (VAS) for global well‐being (1 completed by the physican and 1 by the patient), pain, sleep trouble, fatigue, and feeling refreshed upon awakening. Results. Both FL and AM were associated with significantly improved scores on the FIQ and on the VAS for pain, global well‐being, and sleep disturbances. When combined, the 2 treatments worked better than either medication alone. Similar, but nonsignificant, improvement occurred in the BDI scale, the physician global VAS, and the VAS for fatigue and feeling refreshed upon awakening. Trends were less clear for the tender point score. Conclusion. Both FL and AM are effective treatments for FM, and they work better in combination than either medication alone.
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Cites
Elevated cerebrospinal fluid levels of substance p in patients with the fibromyalgia syndrome
Russell, I. J., Orr, M. D., Littman, B., Vipraio, G. A., Alboukrek, D., Michalek, J. E., Lopez, Y., & Mackillip, F. (1994) · Arthritis & Rheumatism · doi:10.1002/art.1780371106 · Cited by 679
Hypothalamic–pituitary–adrenal axis perturbations in patients with fibromyalgia
Crofford, L. J., Pillemer, S. R., Kalogeras, K. T., Cash, J. M., Michelson, D., Kling, M. A., Sternberg, E. M., Gold, P. W., Chrousos, G. P., & Wilder, R. L. (1994) · Arthritis & Rheumatism · doi:10.1002/art.1780371105 · Cited by 508
The impact of a meditation-based stress reduction program on fibromyalgia.
Kaplan, K. H., Goldenberg, D. L., & Galvin-Nadeau, M. (1993) · General Hospital Psychiatry · doi:10.1016/0163-8343(93)90020-o · Cited by 345
Self-citationA Double-blind Placebo Controlled Trial of Fluoxetine in Fibromyalgia
Wolfe, F., Cathey, M. A., & Hawley, D. J. (1994) · Scandinavian Journal of Rheumatology · doi:10.3109/03009749409103725 · Cited by 252
Cited by
Functional somatic syndromes: one or many?
Wessely, S., Nimnuan, C., & Sharpe, M. (1999) · The Lancet · doi:10.1016/s0140-6736(98)08320-2 · Cited by 1,211
Management of fibromyalgia syndrome
Goldenberg, D. L. (2004) · JAMA · doi:10.1001/jama.292.19.2388 · Cited by 850
Self-citationEULAR evidence-based recommendations for the management of fibromyalgia syndrome
Carville, S. F., Arendt-Nielsen, S., Bliddal, H., Blotman, F., Branco, J. C., Buskila, D., Da Silva, J. A. P., Danneskiold-Samsøe, B., Dincer, F., Henriksson, C., et al. (2008) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2007.071522 · Cited by 752
Arnold, L. M., Lu, Y., Crofford, L. J., Wohlreich, M., Detke, M. J., Iyengar, S., & Goldstein, D. J. (2004) · Arthritis & Rheumatism · doi:10.1002/art.20485 · Cited by 624
Bennett, R. M., Kamin, M., Karim, R., & Rosenthal, N. (2003) · The American Journal of Medicine · doi:10.1016/s0002-9343(03)00116-5 · Cited by 403
Metadata
- Authors
- Goldenberg, D., Mayskiy, M., Mossey, C., Ruthazer, R., & Schmid, C.
- Venue
- Arthritis & Rheumatism
- Publisher
- Wiley
- Published
- 1996-11
- Volume
- 39
- Issue
- 11
- Pages
- 1852-1859
- ISSN
- 0004-3591 (ISSN-L)
- 1529-0131
- OpenAlex
- W1990180765
- Cited by
- 420
- References
- 4
- FWCI
- 11.10
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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