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Cited by 405

The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.

Blood transfusion, smoking, and obesity as risk factors for the development of rheumatoid arthritis. Results from a primary care‐based incident case‐control study in Norfolk, England

Symmons, Deborah P. M., Bankhead, Clare R., Harrison, Beverley J., Brennan, Paul, Silman, Alan J., Barrett, Elizabeth M., Scott, David G. I.·1997·Arthritis & Rheumatism

Abstract

Objective. To examine a range of demographic, social, and clinical risk factors for the development of rheumatoid arthritis (RA). Results. The controls were of higher socioeconomic status than the cases. This was probably due to response bias. Having a body mass index ⩾30 was associated with an adjusted odds ratio (OR) of 3.74 for developing RA (95% confidence interval [95% CI] 1.14−12.27). RA was also associated with a history of blood transfusion (OR 4.83, 95% CI 1.29−18.07). Even after correcting for social class, a history of having ever smoked was associated with a higher risk of developing RA (OR 1.66, 95% CI 0.95−3.06). There was no difference between cases and controls in previous exposure to childhood infections, certain surgical procedures, or reproductive history variables. Methods. Population‐based case‐control study in Norfolk, England, involving adult patients, ages 18–70, with an inflammatory polyarthritis of <12 months' duration who were recruited from the Norfolk Arthritis Register. Controls, matched for sex and date of birth, were selected from the primary care register of the Norwich Health Authority. Both cases and controls completed identical self‐administered questionnaires. Matched analysis of the 165 case‐control sets was conducted for the whole group and for the subset in which the cases satisfied the 1987 American College of Rheumatology criteria for RA. Conclusion. RA has a number of potential environmental triggers, including smoking, obesity, and blood transfusion.

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Metadata

Authors
Symmons, D. P. M., Bankhead, C. R., Harrison, B. J., Brennan, P., Silman, A. J., Barrett, E. M., & Scott, D. G. I.
Venue
Arthritis & Rheumatism
Publisher
Wiley
Published
1997-11
Volume
40
Issue
11
Pages
1955-1961
ISSN
  • 0004-3591 (ISSN-L)
  • 1529-0131
OpenAlex
W1963603430
Cited by
405
References
22
FWCI
4.95
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Blood transfusion, smoking, and obesity as risk factors for the development of rheumatoid arthritis. Results from a primary care‐based incident case‐control study in Norfolk, England. https://app.cochat.ai/papers/10.1002/art.1780401106
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Symmons, D. P. M., Bankhead, C. R., Harrison, B. J., Brennan, P., Silman, A. J., Barrett, E. M., & Scott, D. G. I. (1997). Blood transfusion, smoking, and obesity as risk factors for the development of rheumatoid arthritis. Results from a primary care‐based incident case‐control study in Norfolk, England. Arthritis & Rheumatism. https://doi.org/10.1002/art.1780401106

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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