Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 1,551

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Rheumatoid Arthritis: Pathophysiology and Implications for Therapy

Epstein, Franklin H., Harris, Edward D.·1990·New England Journal of Medicine
DOI 10.1056/nejm199005033221805
Open this paper in CoChat — free account

Abstract

IN 1947, a technician who had rheumatoid arthritis and who worked in the laboratory of Dr. Harry Rose at Columbia University discovered that her own serum agglutinated excessively. Dr. Rose suggested that this serologic reaction might have been caused by the arthritis. Charles Ragan, a rheumatologist, pursued this suggestion and developed the sheep-cell agglutination test,1 , 2 which we know as a test for rheumatoid factor. For the first time, physicians had a key to the black box that was rheumatoid arthritis and could begin to study the immunologic abnormalities in patients with the disease. The classification of patients could also begin; . . .

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1056/nejm199005033221805

Cites

2 of 2 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 2 references

Research works printed but not linked: 158

  1. Benedek, 1987, Ann Intern Med, 106, 304, 10.7326/0003-4819-106-2-304 · doi:10.7326/0003-4819-106-2-304
  2. Rose, 1948, Proc Soc Exp Biol Med, 68, 1, 10.3181/00379727-68-16375 · doi:10.3181/00379727-68-16375
  3. Scott, 1987, Lancet, 1, 1108, 10.1016/S0140-6736(87)91672-2 · DOI · Paper page
  4. Pincus, 1988, J Clin Epidemiol, 41, 1037, 10.1016/0895-4356(88)90072-8 · DOI
  5. Pincus, 1986, J Rheumatol, 13, 841
  6. Mitchell, 1982, Arthritis Rheum, 25, 481, 10.1002/art.1780250501 · doi:10.1002/art.1780250501
  7. Arnett, 1988, Arthritis Rheum, 31, 315, 10.1002/art.1780310302 · DOI · Paper page
  8. McDermott, 1988, Bull Rheum Dis, 38, 1
  9. Gregersen, 1987, Arthritis Rheum, 30, 1205, 10.1002/art.1780301102 · DOI · Paper page
  10. Winchester, 1988, Springer Semin Immunopathol, 10, 119, 10.1007/BF01857219 · doi:10.1007/bf01857219
  11. Gregersen, 1986, Proc Natl Acad Sci U S A, 83, 2642, 10.1073/pnas.83.8.2642 · DOI · Paper page
  12. Nepom, 1989, Arthritis Rheum, 32, 15, 10.1002/anr.1780320104 · doi:10.1002/anr.1780320104
  13. Zoschke, 1986, Hum Immunol, 15, 118, 10.1016/0198-8859(86)90322-8 · doi:10.1016/0198-8859(86)90322-8
  14. Mengle-Gaw, 1984, J Exp Med, 160, 1184, 10.1084/jem.160.4.1184 · DOI
  15. Calin, 1989, Arthritis Rheum, 32, 1221, 10.1002/anr.1780321006 · doi:10.1002/anr.1780321006
  16. Venables, 1989, Curr Opin Rheumatol, 1, 15, 10.1097/00002281-198901010-00005 · DOI
  17. Phillips, 1988, Clin Exp Rheumatol, 6, 87
  18. Alspaugh, 1981, J Clin Invest, 67, 1134, 10.1172/JCI110127 · DOI · Paper page
  19. Venables, 1988, Ann Rheum Dis, 47, 265, 10.1136/ard.47.4.265 · doi:10.1136/ard.47.4.265
  20. Slaughter, 1978, J Exp Med, 148, 1429, 10.1084/jem.148.5.1429 · doi:10.1084/jem.148.5.1429
  21. Yao, 1986, Clin Exp Immunol, 64, 302
  22. Depper, 1981, Arthritis Rheum, 24, 755, 10.1002/art.1780240601 · DOI
  23. Silverman, 1981, Arthritis Rheum, 24, 1465, 10.1002/art.1780241202 · doi:10.1002/art.1780241202
  24. Roudier, 1988, Scand J Immunol, 27, 367, 10.1111/j.1365-3083.1988.tb02359.x · doi:10.1111/j.1365-3083.1988.tb02359.x
  25. Roudier, 1989, Proc Natl Acad Sci U S A, 86, 5104, 10.1073/pnas.86.13.5104 · DOI · Paper page
  26. White, 1985, Lancet, 1, 419, 10.1016/S0140-6736(85)91145-6 · doi:10.1016/s0140-6736(85)91145-6
  27. Cohen, 1986, Ann Rheum Dis, 45, 832, 10.1136/ard.45.10.832 · DOI
  28. Naides, 1988, Arch Intern Med, 148, 2587, 10.1001/archinte.1988.00380120051010 · doi:10.1001/archinte.1988.00380120051010
  29. Simpson, 1984, Science, 223, 1425, 10.1126/science.6701529 · DOI
  30. van Eden, 1988, Nature, 331, 171, 10.1038/331171a0 · DOI · Paper page
  31. Polla, 1988, Immunol Today, 9, 134, 10.1016/0167-5699(88)91199-1 · DOI · Paper page
  32. Tsoulfa, 1989, Ann Rheum Dis, 48, 118, 10.1136/ard.48.2.118 · doi:10.1136/ard.48.2.118
  33. Holoshitz, 1989, Nature, 339, 226, 10.1038/339226a0 · doi:10.1038/339226a0
  34. Stuart, 1984, Annu Rev Immunol, 2, 199, 10.1146/annurev.iy.02.040184.001215 · DOI
  35. Jasin, 1983, Semin Arthritis Rheum, 13, 94, 10.1016/0049-0172(83)90026-4 · DOI
  36. Rowley, 1986, Arthritis Rheum, 29, 174, 10.1002/art.1780290204 · doi:10.1002/art.1780290204
  37. Choi, 1988, Ann Rheum Dis, 47, 313, 10.1136/ard.47.4.313 · doi:10.1136/ard.47.4.313
  38. Mottonen, 1988, Arthritis Rheum, 31, 776, 10.1002/art.1780310612 · doi:10.1002/art.1780310612
  39. Jasin, 1985, Arthritis Rheum, 28, 241, 10.1002/art.1780280302 · DOI · Paper page
  40. Parekh, 1985, Nature, 316, 452, 10.1038/316452a0 · DOI · Paper page
  41. Axford, 1987, Lancet, 2, 1486, 10.1016/S0140-6736(87)92621-3 · doi:10.1016/s0140-6736(87)92621-3
  42. Carson, 1987, Arthritis Rheum, 30, 1321, 10.1002/art.1780301201 · doi:10.1002/art.1780301201
  43. Silverman, 1988, J Clin Invest, 82, 469, 10.1172/JCI113620 · DOI
  44. Moxley, 1989, Arthritis Rheum, 32, 634, 10.1002/anr.1780320518 · doi:10.1002/anr.1780320518
  45. Moxley, 1989, Arthritis Rheum, 32, 1365, 10.1002/anr.1780321104 · doi:10.1002/anr.1780321104
  46. Morel, 1990, Hum Immunol, 27, 90, 10.1016/0198-8859(90)90106-Y · DOI
  47. Stamenkovic, 1988, Proc Natl Acad Sci U S A, 85, 1179, 10.1073/pnas.85.4.1179 · DOI
  48. Koch, 1986, Arthritis Rheum, 29, 471, 10.1002/art.1780290403 · DOI
  49. Folkman, 1987, Science, 235, 442, 10.1126/science.2432664 · DOI · Paper page
  50. Montesano, 1986, Proc Natl Acad Sci U S A, 83, 7297, 10.1073/pnas.83.19.7297 · DOI · Paper page
  51. Herron, 1986, J Biol Chem, 261, 2814, 10.1016/S0021-9258(17)35860-X · DOI · Paper page
  52. Cavender, 1987, Fed Proc, 46, 113
  53. Yu, 1985, Clin Exp Immunol, 62, 554
  54. Cavender, 1986, J Immunol, 136, 203, 10.4049/jimmunol.136.1.203 · DOI · Paper page
  55. Cavender, 1989, Am J Pathol, 134, 551
  56. Jalkanen, 1986, Science, 233, 556, 10.1126/science.3726548 · DOI
  57. Pitzalis, 1988, Eur J Immunol, 18, 1397, 10.1002/eji.1830180915 · DOI · Paper page
  58. van Boxel, 1975, N Engl J Med, 293, 517, 10.1056/NEJM197509112931101 · DOI · Paper page
  59. Pitzalis, 1987, Clin Immunol Immunopathol, 45, 252, 10.1016/0090-1229(87)90040-7 · doi:10.1016/0090-1229(87)90040-7
  60. Lasky, 1988, Arthritis Rheum, 31, 52, 10.1002/art.1780310108 · doi:10.1002/art.1780310108
  61. Pitzalis, 1987, J Rheumatol, 14, 662
  62. Lipsky, 1989, Arthritis Rheum, 32, 1345, 10.1002/anr.1780321102 · doi:10.1002/anr.1780321102
  63. Bonagura, 1989, Ann Rheum Dis, 48, 488, 10.1136/ard.48.6.488 · doi:10.1136/ard.48.6.488
  64. Harris ED Jr. Pathogenesis of rheumatoid arthritis. In: Kelley WN, Harris ED Jr, Ruddy S, Sledge CB, eds. Textbook of rheumatology. 3rd ed. Vol. 1. Philadelphia: W.B. Saunders, 1989:905–42.
  65. Zuraw, 1981, J Clin Invest, 68, 1610, 10.1172/JCI110418 · doi:10.1172/jci110418
  66. Pope, 1974, Proc Natl Acad Sci U S A, 71, 517, 10.1073/pnas.71.2.517 · doi:10.1073/pnas.71.2.517
  67. Shiozawa, 1980, Arthritis Rheum, 23, 816, 10.1002/art.1780230707 · doi:10.1002/art.1780230707
  68. Krane SM, Goldring MB, Goldring SR. Cytokines. In: Cell and molecular biology of vertebrate hard tissues. Ciba Foundation symposium no. 136. New York: John Wiley, 1988:239–56.
  69. Firestein, 1988, J Exp Med, 168, 1573, 10.1084/jem.168.5.1573 · DOI · Paper page
  70. Miyasaka, 1988, Arthritis Rheum, 31, 480, 10.1002/art.1780310404 · doi:10.1002/art.1780310404
  71. Firestein, J Immunol
  72. Hasler, 1988, Br J Rheumatol, 27, 15, 10.1093/rheumatology/27.1.15 · doi:10.1093/rheumatology/27.1.15
  73. Pope, 1984, Arthritis Rheum, 27, 1234, 10.1002/art.1780271105 · doi:10.1002/art.1780271105
  74. Hasler, 1983, J Exp Med, 157, 173, 10.1084/jem.157.1.173 · DOI
  75. Hasler, 1983, J Immunol, 131, 768, 10.4049/jimmunol.131.2.768 · DOI
  76. Lotz, 1986, J Immunol, 136, 3643, 10.4049/jimmunol.136.10.3643 · DOI
  77. Edwards, 1987, Embo J, 6, 1899, 10.1002/j.1460-2075.1987.tb02449.x · DOI · Paper page
  78. Wahl, 1988, J Immunol, 140, 3026, 10.4049/jimmunol.140.9.3026 · DOI · Paper page
  79. Fava, 1989, J Exp Med, 169, 291, 10.1084/jem.169.1.291 · DOI · Paper page
  80. Dayer J-M, Seckinger P. Natural inhibitors and antagonists of interleukin-1. In: Bomford R, Henderson B, eds. Interleukin-1, inflammation and disease. New York: Elsevier Science, 1989:283–302.
  81. Levine, 1985, J Rheumatol, 12, 406
  82. Levine, 1987, Rheum Dis Clin North Am, 13, 369, 10.1016/S0889-857X(21)00853-X · DOI
  83. Lotz, 1988, Science, 241, 1218, 10.1126/science.2457950 · DOI · Paper page
  84. Lotz, 1987, Science, 235, 893, 10.1126/science.2433770 · DOI · Paper page
  85. Fernandez, 1978, J Immunol, 120, 109, 10.4049/jimmunol.120.1.109 · DOI · Paper page
  86. Lee TC, Snyder F. Function, metabolism and regulation of platelet activating factor and related ether lipids. In: Kuo JF, ed. Phospholipids and cellular regulation. Boca Raton, Fla.: CRC Press, 1985:1–39.
  87. Ford-Hutchinson, 1980, Nature, 286, 264, 10.1038/286264a0 · DOI · Paper page
  88. Korchak, 1984, Fed Proc, 43, 2749
  89. Henson, 1987, J Clin Invest, 79, 669, 10.1172/JCI112869 · DOI · Paper page
  90. Hibbs, 1984, Coll Relat Res, 4, 467, 10.1016/S0174-173X(84)80013-8 · doi:10.1016/s0174-173x(84)80013-8
  91. Elmgreen, 1987, Ann Rheum Dis, 46, 501, 10.1136/ard.46.7.501 · doi:10.1136/ard.46.7.501
  92. Bevilacqua, 1989, Science, 243, 1160, 10.1126/science.2466335 · DOI · Paper page
  93. Gimbrone, 1989, Science, 246, 1601, 10.1126/science.2688092 · DOI · Paper page
  94. Elmgreen, 1985, Ann Rheum Dis, 44, 514, 10.1136/ard.44.8.514 · doi:10.1136/ard.44.8.514
  95. Goldstein, 1974, J Immunol, 113, 1583, 10.4049/jimmunol.113.5.1583 · DOI · Paper page
  96. Van De Putte, 1977, Arthritis Rheum, 20, 671, 10.1002/art.1780200206 · doi:10.1002/art.1780200206
  97. Werb, 1977, N Engl J Med, 296, 1017, 10.1056/NEJM197705052961801 · DOI · Paper page
  98. Okada, 1988, Biochem, 254, 731, 10.1042/bj2540731 · DOI
  99. Hollingsworth, 1967, Yale J Biol Med, 39, 289
  100. Harris, 1975, Clin Orthop, 110, 303, 10.1097/00003086-197507000-00041 · doi:10.1097/00003086-197507000-00041
  101. Jacoby, 1973, Br Med J, 2, 96, 10.1136/bmj.2.5858.96 · DOI · Paper page
  102. Fleming, 1976, Ann Rheum Dis, 35, 357, 10.1136/ard.35.4.357 · doi:10.1136/ard.35.4.357
  103. Fleming, 1976, Ann Rheum Dis, 35, 361, 10.1136/ard.35.4.361 · doi:10.1136/ard.35.4.361
  104. Harris ED Jr. The clinical features of rheumatoid arthritis. In: Kelley WM, Harris ED Jr, Ruddy S, Sledge C, eds. Textbook of rheumatology. 3rd ed. Vol. 1. Philadelphia: W.B. Saunders, 1989:943–81.
  105. Thompson, 1987, Arthritis Rheum, 30, 618, 10.1002/art.1780300603 · DOI · Paper page
  106. Guerne, 1989, J Clin Invest, 83, 585, 10.1172/JCI113921 · DOI · Paper page
  107. Winchester, 1971, Arthritis Rheum, 14, 650, 10.1002/art.1780140513 · doi:10.1002/art.1780140513
  108. Hutchinson, 1976, Ann Rheum Dis, 35, 138, 10.1136/ard.35.2.138 · doi:10.1136/ard.35.2.138
  109. Anderson, 1989, Arthritis Rheum, 32, 1093, 10.1002/anr.1780320907 · DOI
  110. Harris ED Jr. Management of rheumatoid arthritis. In: Kelley WN, Harris ED Jr, Ruddy S, Sledge CB, eds. Textbook of rheumatology. 3rd ed. Vol. 1. Philadelphia: W.B. Saunders, 1989:982–92.
  111. Klippel, 1989, Bull Rheum Dis, 38, 1
  112. Lorig, 1985, Arthritis Rheum, 28, 680, 10.1002/art.1780280612 · DOI · Paper page
  113. Merry, 1989, Ann Rheum Dis, 48, 864, 10.1136/ard.48.10.864 · DOI
  114. Pike, 1989, J Rheumatol, 16, 718
  115. Sperling, 1987, Arthritis Rheum, 30, 988, 10.1002/art.1780300905 · DOI · Paper page
  116. Endres, 1989, N Engl J Med, 320, 265, 10.1056/NEJM198902023200501 · DOI · Paper page
  117. Kremer, 1987, Ann Intern Med, 106, 497, 10.7326/0003-4819-106-4-497 · DOI · Paper page
  118. Kremer, 1988, Arthritis Rheum, 31, 530
  119. Paulus HE. Nonsteroidal anti-inflammatory drugs. In: Kelley WM, Harris ED Jr, Ruddy S, Sledge C, eds. Textbook of rheumatology. 3rd ed. Vol. 1. Philadelphia: W.B. Saunders, 1989:765–91.
  120. Harris, 1983, J Rheumatol, 10, 713
  121. Sambrook, 1989, Ann Rheum Dis, 48, 535, 10.1136/ard.48.7.535 · DOI
  122. Tugwell, 1987, Ann Intern Med, 107, 358, 10.7326/0003-4819-107-2-358 · DOI · Paper page
  123. Gordon DA. Gold compounds. In: Kelley WM, Harris ED Jr, Ruddy S, Sledge C, eds. Textbook of rheumatology. 3rd ed. Vol. 1. Philadelphia: W.B. Saunders, 1989:804–23.
  124. Lafyatis, 1989, J Clin Invest, 83, 1267, 10.1172/JCI114011 · DOI · Paper page
  125. Burmester, 1983, Scand J Immunol, 17, 69, 10.1111/j.1365-3083.1983.tb00767.x · doi:10.1111/j.1365-3083.1983.tb00767.x
  126. Goto, 1987, J Clin Invest, 80, 786, 10.1172/JCI113135 · doi:10.1172/jci113135
  127. Woolley, 1978, Science, 200, 773, 10.1126/science.205952 · doi:10.1126/science.205952
  128. Stephenson, 1987, Biochem Biophys Res Commun, 144, 583, 10.1016/S0006-291X(87)80006-2 · doi:10.1016/s0006-291x(87)80006-2
  129. Conca, 1989, J Clin Invest, 83, 1753, 10.1172/JCI114077 · DOI
  130. Eisen AA, Bauer EA, Stricklin GP, Seltzer JL, Koob TJ, Jeffrey JJ. Control of human skin collagenase activity. In: McCabe BF, Sadé J, Abramson M, eds. Cholesteatoma: First International Conference. Birmingham, Ala.: Aesculapius Publishing, 1977:115–23.
  131. Carmichael, 1986, Proc Natl Acad Sci U S A, 83, 2407, 10.1073/pnas.83.8.2407 · DOI · Paper page
  132. Pinals, 1987, Arthritis Rheum, 30, 473, 10.1002/art.1780300421 · DOI
  133. Sherrer, 1986, Arthritis Rheum, 29, 494, 10.1002/art.1780290406 · DOI · Paper page
  134. Erhardt, 1989, Ann Rheum Dis, 48, 7, 10.1136/ard.48.1.7 · doi:10.1136/ard.48.1.7
  135. Callahan, 1988, Arthritis Rheum, 31, 1346, 10.1002/art.1780311102 · DOI
  136. Regan-Smith, 1989, Arthritis Rheum, 32, 128, 10.1002/anr.1780320203 · doi:10.1002/anr.1780320203
  137. Withrington, 1984, Ann Rheum Dis, 43, 679, 10.1136/ard.43.5.679 · doi:10.1136/ard.43.5.679
  138. Ochi, 1984, Arthritis Rheum, 27, 883, 10.1002/art.1780270807 · doi:10.1002/art.1780270807
  139. Hørslev-Peterson, 1986, Arthritis Rheum, 29, 592, 10.1002/art.1780290503 · doi:10.1002/art.1780290503
  140. Black, 1989, Ann Rheum Dis, 48, 641, 10.1136/ard.48.8.641 · DOI
  141. Sharp, 1989, Arthritis Rheum, 32, 221, 10.1002/anr.1780320218 · doi:10.1002/anr.1780320218
  142. Gilkeson, 1988, J Rheumatol, 15, 1361
  143. Salisbury, 1985, Clin Orthop, 199, 242, 10.1097/00003086-198510000-00035 · doi:10.1097/00003086-198510000-00035
  144. Williams, 1982, Lancet, 2, 237, 10.1016/S0140-6736(82)90323-3 · DOI
  145. Gaston, 1988, Arthritis Rheum, 31, 21, 10.1002/art.1780310104 · doi:10.1002/art.1780310104
  146. Yocum, 1988, Ann Intern Med, 109, 863, 10.7326/0003-4819-109-11-863 · DOI
  147. Dougados, 1988, Ann Rheum Dis, 47, 127, 10.1136/ard.47.2.127 · doi:10.1136/ard.47.2.127
  148. Dougados, 1989, Ann Rheum Dis, 48, 550, 10.1136/ard.48.7.550 · doi:10.1136/ard.48.7.550
  149. Folkman, 1989, Science, 243, 1490, 10.1126/science.2467380 · DOI · Paper page
  150. Sany, 1982, Arthritis Rheum, 25, 17, 10.1002/art.1780250103 · doi:10.1002/art.1780250103
  151. Kyle, 1989, Ann Rheum Dis, 48, 428, 10.1136/ard.48.5.428 · doi:10.1136/ard.48.5.428
  152. Herzog, 1989, J Autoimmun, 2, 627, 10.1016/S0896-8411(89)80002-2 · doi:10.1016/s0896-8411(89)80002-2
  153. Walker, 1989, J Autoimmun, 2, 643, 10.1016/S0896-8411(89)80003-4 · doi:10.1016/s0896-8411(89)80003-4
  154. Shmerling, 1989, Arthritis Rheum, 32, 1495, 10.1002/anr.1780321133 · doi:10.1002/anr.1780321133
  155. Gamble, 1988, Science, 242, 97, 10.1126/science.3175638 · DOI · Paper page
  156. Herzog, 1989, Concepts Immunopathol, 7, 79
  157. Sledge, 1986, Arthritis Rheum, 29, 153, 10.1002/art.1780290201 · doi:10.1002/art.1780290201
  158. Vella, 1988, Arthritis Rheum, 31, 789, 10.1002/art.1780310615 · doi:10.1002/art.1780310615

Cited by

See all 1,551

Metadata

Authors
Epstein, F. H., & Harris, E. D.
Venue
New England Journal of Medicine
Publisher
Massachusetts Medical Society
Published
1990-05-03
Volume
322
Issue
18
Pages
1277-1289
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
DOI
10.1056/nejm199005033221805
OpenAlex
W2133692536
Cited by
1,551
References
2
FWCI
48.65
Type
journal article
Language
en
Open access
closed

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Rheumatoid Arthritis: Pathophysiology and Implications for Therapy. https://app.cochat.ai/papers/10.1056/nejm199005033221805
The paper
Epstein, F. H., & Harris, E. D. (1990). Rheumatoid Arthritis: Pathophysiology and Implications for Therapy. New England Journal of Medicine. https://doi.org/10.1056/nejm199005033221805

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.