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Formal education and five‐year mortality in rheumatoid arthritis: Mediation by helplessness scale scores
Abstract
Objective To analyze scores on a scale designed to measure helplessness, a cognitive variable, as a possible mediator of the association between formal education level and mortality over 5 years in patients with rheumatoid arthritis (RA). Methods A cohort of 1,416 patients with RA from 15 private practices in 6 states and Washington, DC was monitored for over 5 years. Demographic, socioeconomic, therapy, functional status, and psychological variables were analyzed as possible predictors of mortality in invariable and multivariable Cox Proportional Hazards models. Results In a 5-year followup, 1,384 patients were accounted for (97.3%), including 174 who died versus 111 expected (standardized mortality ratio = 1.54). Higher mortality was associated significantly with low formal education, high age, poor scores for activities of daily living (ADL) on a modified health assessment questionnaire (MHAQ), and poor scores on a helplessness scale (all P Conclusion Scores on a helplessness scale appear to mediate a component of the association between formal education level and 5-year mortality in these patients with RA. Health professionals and policy makers might consider interventions directed at modification of helplessness as adjunctive to standard interventions to improve outcomes in RA.
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In the citing paper
“They also suggest that interventions designed to reduce helplessness might be useful in reducing early death in patients with rheumatoid arthritis.”
From Psychological aspects of persistent pain: Current state of the science (2004) · cites this paper as [16]
In the citing paper
“As expected, the results revealed that individuals with low formal education and higher levels of disease activity had a significantly higher risk for early death.”
From Psychological aspects of persistent pain: Current state of the science (2004) · cites this paper as [16]
In the citing paper
“These results suggest that helplessness might actually explain why persons with limited formal education and rheumatoid arthritis die earlier”
From Psychological aspects of persistent pain: Current state of the science (2004) · cites this paper as [16]
In the citing paper
“However, to date, interventions to decrease helplessness have not been reimbursed and thus are not being widely used in the medical management of rheumatic pain conditions.16”
From Psychological aspects of persistent pain: Current state of the science (2004) · cites this paper as [16]
In the citing paper
“To our knowledge, this result has been reported in only one study,16”
From Psychological aspects of persistent pain: Current state of the science (2004) · cites this paper as [16]
In the citing paper
“However, when helplessness was entered into a model predicting mortality, education level was no longer found to be a significant predictor.”
From Psychological aspects of persistent pain: Current state of the science (2004) · cites this paper as [16]
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Metadata
- Authors
- Callahan, L. F., Cordray, D. S., Wells, G., & Pincus, T.
- Affiliations
- University of North Carolina at Chapel Hill (US)
- Vanderbilt University (US)
- University of Ottawa (CA)
- Corresponding author
- Callahan, Leigh F.
- Venue
- Arthritis & Rheumatism
- Publisher
- Wiley
- Published
- 1996-12
- Volume
- 9
- Issue
- 6
- Pages
- 463-472
- ISSN
- 0004-3591 (ISSN-L)
- 1529-0131
- OpenAlex
- W2067851921
- Cited by
- 111
- References
- 91
- Citations by year
- 2022: 1 · 2021: 1 · 2020: 3 · 2019: 2 · 2018: 1 · 2017: 3 · 2016: 1 · 2015: 2 · 2014: 2 · 2013: 4 · 2012: 4
- FWCI
- 3.64
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Arthritis & Rheumatism (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Public Health Service (21393)
- Topics
- Health Sciences › Medicine › Rheumatology › Rheumatoid Arthritis Research and Therapies
- Social Sciences › Health › Health disparities and outcomes
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
- Keywords
- rheumatoid arthritis, mortality, helplessness, formal education, mediation, activities of daily living, modified Health Assessment Questionnaire, age, sex differences, socioeconomic factors, psychological factors
- MeSH terms
- Adult, Aged, Arthritis, Rheumatoid, Educational Status, Female, Health Status, Helplessness, Learned, Humans, Longitudinal Studies, Male, Middle Aged, Patient Education as Topic, Surveys and Questionnaires, Proportional Hazards Models
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