The DOI matches its Crossref record; 79 of the 79 references it cites were found in a registry or an index.
Anti–citrullinated peptide antibody assays and their role in the diagnosis of rheumatoid arthritis
Open accessAbstract
Increasingly, assays for the detection of anti-citrullinated peptide antibodies (ACPA) are used in RA diagnosis. This review summarizes the biologic basis and development of ACPA assays, available ACPA assays and their performance characteristics, and diagnostic properties of ACPA alone and compared to rheumatoid factor (RF) in early RA. We also review correlations, precision, costs and cost-effectiveness, availability, stability and reproducibility of the available assays. Taken together, data indicate that ACPA has a higher specificity than RF for early RA, good predictive validity, high sensitivity, apparent cost-effectiveness and good stability and reproducibility. Given its superior performance characteristics and increasing availability, ACPA is emerging as the most useful single assay for the diagnosis of RA.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Arnett, F. C., Edworthy, S. M., Bloch, D. A., Mcshane, D. J., Fries, J. F., Cooper, N. S., Healey, L. A., Kaplan, S. R., Liang, M. H., Luthra, H. S., et al. (1988) · Arthritis & Rheumatism · doi:10.1002/art.1780310302 · Cited by 19,752
Revised Criteria for the Classification of Rheumatoid Arthritis
Arnett, F. C. (1990) · Orthopaedic Nursing · doi:10.1097/00006416-199003000-00011 · Cited by 7,723
Rantapää‐Dahlqvist, S., de Jong, B. A. W., Berglin, E., Hallmans, G., Wadell, G., Stenlund, H., Sundin, U., & van Venrooij, W. J. (2003) · Arthritis & Rheumatism · doi:10.1002/art.11223 · Cited by 1,953
Nielen, M. M. J., van Schaardenburg, D., Reesink, H. W., van de Stadt, R. J., van der Horst‐Bruinsma, I. E., de Koning, M. H. M. T., Habibuw, M. R., Vandenbroucke, J. P., & Dijkmans, B. A. C. (2004) · Arthritis & Rheumatism · doi:10.1002/art.20018 · Cited by 1,861
Klareskog, L., Stolt, P., Lundberg, K., Källberg, H., Bengtsson, C., Grunewald, J., Rönnelid, J., Erlandsson Harris, H., Ulfgren, A., Rantapää‐Dahlqvist, S., et al. (2006) · Arthritis & Rheumatism · doi:10.1002/art.21575 · Cited by 1,515
Schellekens, G. A., Visser, H., De Jong, B. A. W., Van Den Hoogen, F. H. J., Hazes, J. M. W., Breedveld, F. C., & Van Venrooij, W. J. (2000) · Arthritis & Rheumatism · doi:10.1002/1529-0131(200001)43:1<155::aid-anr20>3.0.co;2-3 · Cited by 1,450
Schellekens, G. A., de Jong, B. A., van den Hoogen, F. H., van de Putte, L. B., & van Venrooij, W. J. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1316 · Cited by 1,450
Nishimura, K., Sugiyama, D., Kogata, Y., Tsuji, G., Nakazawa, T., Kawano, S., Saigo, K., Morinobu, A., Koshiba, M., Kuntz, K. M., et al. (2007) · Annals of Internal Medicine · doi:10.7326/0003-4819-146-11-200706050-00008 · Cited by 873
How to diagnose rheumatoid arthritis early: A prediction model for persistent (erosive) arthritis
Visser, H., le Cessie, S., Vos, K., Breedveld, F. C., & Hazes, J. M. W. (2002) · Arthritis & Rheumatism · doi:10.1002/art.10117 · Cited by 731
Use of Coefficient of Variation in Assessing Variability of Quantitative Assays
Reed, G. F., Lynn, F., & Meade, B. D. (2002) · Clinical and Vaccine Immunology · doi:10.1128/cdli.9.6.1235-1239.2002 · Cited by 712
Cited by
Aletaha, D., Neogi, T., Silman, A. J., Funovits, J., Felson, D. T., Bingham, C. O., Birnbaum, N. S., Burmester, G. R., Bykerk, V. P., Cohen, M. D., et al. (2010) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2010.138461 · Cited by 4,941
Update on the Pathomechanism, Diagnosis, and Treatment Options for Rheumatoid Arthritis
Lin, Y.-J., Anzaghe, M., & Schülke, S. (2020) · Cells · doi:10.3390/cells9040880 · Cited by 932
Yap, H.-Y., Tee, S. Z.-Y., Wong, M. M.-T., Chow, S.-K., Peh, S.-C., & Teow, S.-Y. (2018) · Cells · doi:10.3390/cells7100161 · Cited by 486
Harris, H. R., Costenbader, K. H., Mu, F., Kvaskoff, M., Malspeis, S., Karlson, E. W., & Missmer, S. A. (2016) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2015-207704 · Cited by 112
Metadata
- Authors
- Aggarwal, R., Liao, K., Nair, R., Ringold, S., & Costenbander, K. H.
- Venue
- Arthritis Care & Research
- Publisher
- Wiley
- Published
- 2009-10-29
- Volume
- 61
- Issue
- 11
- Pages
- 1472-1483
- ISSN
- 0893-7524 (ISSN-L)
- 1529-0123
- OpenAlex
- W2008861688
- Cited by
- 253
- References
- 79
- FWCI
- 5.28
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Anti–citrullinated peptide antibody assays and their role in the diagnosis of rheumatoid arthritis. https://app.cochat.ai/papers/10.1002/art.24827
- The paper
- Aggarwal, R., Liao, K., Nair, R., Ringold, S., & Costenbander, K. H. (2009). Anti–citrullinated peptide antibody assays and their role in the diagnosis of rheumatoid arthritis. Arthritis Care & Research. https://doi.org/10.1002/art.24827
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
