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Cited by 312

The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.

Non‐coding RNAs: Meet thy masters

Costa, Fabrício F.·2010·BioEssays

Abstract

New DNA sequencing technologies have provided novel insights into eukaryotic genomes, epigenomes, and the transcriptome, including the identification of new non‐coding RNA (ncRNA) classes such as promoter‐associated RNAs and long RNAs. Moreover, it is now clear that up to 90% of eukaryotic genomes are transcribed, generating an extraordinary range of RNAs with no coding capacity. Taken together, these new discoveries are modifying the status quo in genomic science by demonstrating that the eukaryotic gene pool is divided into two distinct categories of transcripts: protein‐coding and non‐coding. The function of the majority of ncRNAs produced by the transcriptome is largely unknown; however, it is probable that many are associated with epigenetic mechanisms. The purpose of this review is to describe the most recent discoveries in the ncRNA field that implicate these molecules as key players in the epigenome.

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Metadata

Authors
Costa, F. F.
Venue
BioEssays
Publisher
Wiley
Published
2010-06-28
Volume
32
Issue
7
Pages
599-608
ISSN
  • 0265-9247 (ISSN-L)
  • 1521-1878
OpenAlex
W1992741792
Cited by
312
References
14
FWCI
1.63
Type
journal article
Language
en
Open access
closed

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Costa, F. F. (2010). Non‐coding RNAs: Meet thy masters. BioEssays. https://doi.org/10.1002/bies.200900112

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