The DOI matches its Crossref record; 64 of the 64 references it cites were found in a registry or an index.
Biotin
Open accessAbstract
Biotin is a water‐soluble vitamin and serves as a coenzyme for five carboxylases in humans. Biotin is also covalently attached to distinct lysine residues in histones, affecting chromatin structure and mediating gene regulation. This review describes mammalian biotin metabolism, biotin analysis, markers of biotin status, and biological functions of biotin. Proteins such as holocarboxylase synthetase, biotinidase, and the biotin transporters SMVT and MCT1 play crucial roles in biotin homeostasis, and these roles are reviewed here. Possible effects of inadequate biotin intake, drug interactions, and inborn errors of metabolism are discussed, including putative effects on birth defects. © 2009 International Union of Biochemistry and Molecular Biology, Inc.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Jenuwein, T., & Allis, C. D. (2001) · Science · doi:10.1126/science.1063127 · Cited by 9,756
Chen, X., Xiu, M., Xing, J., Yu, S., Min, D., & Guo, F. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000479439 · Cited by 5,742
(1998) · National Academies Press eBooks · doi:10.17226/6015 · Cited by 2,435
Green, N. M. (1975) · Advances in Protein Chemistry · doi:10.1016/s0065-3233(08)60411-8 · Cited by 1,458
Histone and chromatin cross-talk
Fischle, W., Wang, Y., & Allis, C. D. (2003) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(03)00013-9 · Cited by 1,207
The histone H4 acetyltransferase MOF uses a C 2 HC zinc finger for substrate recognition
Akhtar, A., & Becker, P. B. (2001) · EMBO reports · doi:10.1093/embo-reports/kve022 · Cited by 632
THE MECHANISM OF BIOTIN-DEPENDENT ENZYMES
Knowles, J. R. (1989) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.58.070189.001211 · Cited by 471
Present Knowledge in Nutrition
Hudson, N. R. (2007) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/85.5.1439a · Cited by 411
REGULATION OF MAMMALIAN ACETYL-COENZYME A CARBOXYLASE
Kim, K.-H. (1997) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.17.1.77 · Cited by 392
Prasad, P. D., Wang, H., Kekuda, R., Fujita, T., Fei, Y.-J., Devoe, L. D., Leibach, F. H., & Ganapathy, V. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.13.7501 · Cited by 229
Cited by
Recent development of biotin conjugation in biological imaging, sensing, and target delivery
Ren, W. X., Han, J., Uhm, S., Jang, Y. J., Kang, C., Kim, J.-H., & Kim, J. S. (2015) · Chemical Communications · doi:10.1039/c5cc03075g · Cited by 393
One Hundred Years of Vitamins—A Success Story of the Natural Sciences
Eggersdorfer, M., Laudert, D., Létinois, U., McClymont, T., Medlock, J., Netscher, T., & Bonrath, W. (2012) · Angewandte Chemie International Edition · doi:10.1002/anie.201205886 · Cited by 344
Ogawa, Y., Kinoshita, M., Shimada, S., & Kawamura, T. (2018) · Nutrients · doi:10.3390/nu10020199 · Cited by 214
Single- versus Dual-Targeted Nanoparticles with Folic Acid and Biotin for Anticancer Drug Delivery
Jurczyk, M., Jelonek, K., Musiał-Kulik, M., Beberok, A., Wrześniok, D., & Kasperczyk, J. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13030326 · Cited by 133
Nutrient effects on motor neurons and the risk of amyotrophic lateral sclerosis
Goncharova, P. S., Davydova, T. K., Popova, T. E., Novitsky, M. A., Petrova, M. M., Gavrilyuk, O. A., Al-Zamil, M., Zhukova, N. G., Nasyrova, R. F., & Shnayder, N. A. (2021) · Nutrients · doi:10.3390/nu13113804 · Cited by 35
Metadata
- Authors
- Zempleni, J., Wijeratne, S. S. K., & Hassan, Y. I.
- Venue
- BioFactors
- Publisher
- Wiley
- Published
- 2009-01
- Volume
- 35
- Issue
- 1
- Pages
- 36-46
- ISSN
- 0951-6433 (ISSN-L)
- 1872-8081
- OpenAlex
- W4211170577
- Cited by
- 365
- References
- 64
- FWCI
- 4.55
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Biotin. https://app.cochat.ai/papers/10.1002/biof.8
- The paper
- Zempleni, J., Wijeratne, S. S. K., & Hassan, Y. I. (2009). Biotin. BioFactors. https://doi.org/10.1002/biof.8
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
