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Alginate as immobilization material: I. Correlation between chemical and physical properties of alginate gel beads
Abstract
Calcium alginate gel beads were prepared from a range of well characterized alginates. The physical properties of beads depended strongly on the composition, sequential structure, and molecular size of the polymers. Beads with the highest mechanical strength, lowest shrinkage, best stability towards monovalent cations, and highest porosity were made from alginate with a content of L‐guluronic acid higher than 70% and an average length of the G‐blocks higher than 15. For these “high G” alginates the critical overlap intrinsic viscosities have been determined, and for molecular weight higher than 2.4 × 10 5, the gel strength was independent of the molecular weight.
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Cited by
A practical guide to hydrogels for cell culture
Caliari, S. R., & Burdick, J. A. (2016) · Nature Methods · doi:10.1038/nmeth.3839 · Cited by 2,075
Main properties and current applications of some polysaccharides as biomaterials
Rinaudo, M. (2008) · Polymer International · doi:10.1002/pi.2378 · Cited by 1,028
Wong, T. Y., Preston, L. A., & Schiller, N. L. (2000) · Annual Review of Microbiology · doi:10.1146/annurev.micro.54.1.289 · Cited by 669
Ions-induced gelation of alginate: Mechanisms and applications
Hu, C., Lu, W., Mata, A., Nishinari, K., & Fang, Y. (2021) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2021.02.086 · Cited by 600
Injectable alginate hydrogels for cell delivery in tissue engineering
Bidarra, S. J., Barrias, C. C., & Granja, P. L. (2014) · Acta Biomaterialia · doi:10.1016/j.actbio.2013.12.006 · Cited by 534
Metadata
- Authors
- Martinsen, A., Skjåk‐Bræk, G., & Smidsrød, O.
- Venue
- Biotechnology and Bioengineering
- Publisher
- Wiley
- Published
- 1989-01-05
- Volume
- 33
- Issue
- 1
- Pages
- 79-89
- ISSN
- 0006-3592 (ISSN-L)
- 1097-0290
- OpenAlex
- W2042435016
- Cited by
- 942
- References
- 0
- FWCI
- 15.40
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Alginate as immobilization material: I. Correlation between chemical and physical properties of alginate gel beads. https://app.cochat.ai/papers/10.1002/bit.260330111
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- Martinsen, A., Skjåk‐Bræk, G., & Smidsrød, O. (1989). Alginate as immobilization material: I. Correlation between chemical and physical properties of alginate gel beads. Biotechnology and Bioengineering. https://doi.org/10.1002/bit.260330111
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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