The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Total mesorectal excision and local recurrence: A study of tumour spread in the mesorectum distal to rectal cancer
Abstract
Total mesorectal excision (TME) appears to be associated with a reduced local recurrence rate following surgery for rectal cancer. Of 20 patients with rectal cancer in whom TME was performed, adenocarcinoma was found in the distal mesorectum in four. Distal mesorectal spread often extended further than intramural spread. Patients with tumour in the distal mesorectum had a worse outcome at 4-year follow-up, a greater risk of local recurrence and an increased frequency of distant metastasis. Distal tumour spread is, therefore, a marker of poor prognosis in rectal cancer. This study provides further evidence that incomplete excision of the mesorectum contributes to local recurrence in a proportion of patients with rectal cancer, particularly in those with tumours in the middle and lower third of the rectum.
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Citations
Cites
The mesorectum in rectal cancer surgery—the clue to pelvic recurrence?
Heald, R. J., Husband, E. M., & Ryall, R. D. H. (1982) · Journal of British Surgery · doi:10.1002/bjs.1800691019 · Cited by 2,917
LOCAL RECURRENCE OF RECTAL ADENOCARCINOMA DUE TO INADEQUATE SURGICAL RESECTION
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Self-citationMesorectal excision for rectal cancer
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Role of circumferential margin involvement in the local recurrence of rectal cancer
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Self-citationImpact of variability among surgeons on postoperative morbidity and mortality and ultimate survival.
McArdle, C. S., & Hole, D. (1991) · BMJ · doi:10.1136/bmj.302.6791.1501 · Cited by 538
The grading of rectal cancer: historical perspectives and a multivariate analysis of 447 cases
JASS, J. R., ATKIN, W. S., CUZICK, J., BUSSEY, H. J. R., MORSON, B. C., NORTHOVER, J. M. A., & TODD, I. P. (1986) · Histopathology · doi:10.1111/j.1365-2559.1986.tb02497.x · Cited by 538
Local recurrence following ‘curative’ surgery for large bowel cancer: I. The overall picture
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The prediction of local recurrence in rectal adenocarcinoma by histopathological examination
Quirke, P., & Dixon, M. F. (1988) · International Journal of Colorectal Disease · doi:10.1007/bf01645318 · Cited by 334
Self-citationLewis, W. G., Holdsworth, P. J., Stephenson, B. M., Finan, P. J., & Johnston, D. (1992) · Journal of British Surgery · doi:10.1002/bjs.1800791032 · Cited by 173
Self-citationAppropriateness of cholecystectomy in the United Kingdom--a consensus panel approach.
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Cited by
Is local excision adequate therapy for early rectal cancer?
Mellgren, A., Sirivongs, P., Rothenberger, D. A., Madoff, R. D., & García-Aguilar, J. (2000) · Diseases of the Colon & Rectum · doi:10.1007/bf02236551 · Cited by 443
Risk factors for anastomotic leakage after low anterior resection with total mesorectal excision
Law, W.-L., Chu, K.-W., Ho, J. W. C., & Chan, C.-W. (2000) · The American Journal of Surgery · doi:10.1016/s0002-9610(00)00252-x · Cited by 381
Bhome, R., Goh, R. W., Bullock, M. D., Pillar, N., Thirdborough, S. M., Mellone, M., Mirnezami, R., Galea, D., Veselkov, K., Gu, Q., et al. (2017) · Aging · doi:10.18632/aging.101355 · Cited by 155
Metadata
- Authors
- Scott, N., Jackson, P., Al-Jaberi, T., Dixon, M. F., Quirke, P., & Finan, P. J.
- Venue
- Journal of British Surgery
- Publisher
- Oxford University Press (OUP)
- Published
- 1995-08-01
- Volume
- 82
- Issue
- 8
- Pages
- 1031-1033
- ISSN
- 0007-1323 (ISSN-L)
- 1365-2168
- OpenAlex
- W1994362503
- Cited by
- 335
- References
- 12
- FWCI
- 5.60
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Total mesorectal excision and local recurrence: A study of tumour spread in the mesorectum distal to rectal cancer. https://app.cochat.ai/papers/10.1002/bjs.1800820808
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- Scott, N., Jackson, P., Al-Jaberi, T., Dixon, M. F., Quirke, P., & Finan, P. J. (1995). Total mesorectal excision and local recurrence: A study of tumour spread in the mesorectum distal to rectal cancer. Journal of British Surgery. https://doi.org/10.1002/bjs.1800820808
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.