The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Exploring and Exploiting the Therapeutic Potential of Glycoconjugates
Abstract
Carbohydrates, either bound to proteins or in lipids, play essential roles as communication molecules in many intercellular and intracellular processes. In particular, carbohydrates are important mediators of cell–cell recognition events and have been implicated in related processes such as cell signaling regulation, cellular differentiation and immune response. This diverse utility has long suggested the power of carbohydrates in therapeutic approaches. This Concepts article highlights the recent potential uses of glycoconjugates as therapeutics, with particular reference to glycopeptides, glycoproteins, glycodendrimers, and glycoarrays.
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Cites
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Glycosylation and the Immune System
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Regulation of Notch Signaling by O-Linked Fucose
Okajima, T., & Irvine, K. D. (2002) · Cell · doi:10.1016/s0092-8674(02)01114-5 · Cited by 386
Cited by
Chemical Modification of Proteins at Cysteine: Opportunities in Chemistry and Biology
Chalker, J. M., Bernardes, G. J. L., Lin, Y. A., & Davis, B. G. (2009) · Chemistry – An Asian Journal · doi:10.1002/asia.200800427 · Cited by 649
Self-citationGlycomimetics versus Multivalent Glycoconjugates for the Design of High Affinity Lectin Ligands
Cecioni, S., Imberty, A., & Vidal, S. (2015) · Chemical Reviews · doi:10.1021/cr500303t · Cited by 544
Multivalent glycoconjugates as anti-pathogenic agents
Bernardi, A., Jiménez-Barbero, J., Casnati, A., De Castro, C., Darbre, T., Fieschi, F., Finne, J., Funken, H., Jaeger, K.-E., Lahmann, M., et al. (2013) · Chem. Soc. Rev. · doi:10.1039/c2cs35408j · Cited by 537
van Dongen, S. F. M., de Hoog, H.-P. M., Peters, R. J. R. W., Nallani, M., Nolte, R. J. M., & van Hest, J. C. M. (2009) · Chemical Reviews · doi:10.1021/cr900072y · Cited by 386
A “Tag-and-Modify” Approach to Site-Selective Protein Modification
Chalker, J. M., Bernardes, G. J. L., & Davis, B. G. (2011) · Accounts of Chemical Research · doi:10.1021/ar200056q · Cited by 354
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Metadata
- Authors
- Doores, K. J., Gamblin, D. P., & Davis, B. G.
- Venue
- Chemistry – A European Journal
- Publisher
- Wiley
- Published
- 2006-01-05
- Volume
- 12
- Issue
- 3
- Pages
- 656-665
- ISSN
- 0947-6539 (ISSN-L)
- 1521-3765
- OpenAlex
- W2124298469
- Cited by
- 164
- References
- 6
- FWCI
- 4.38
- Type
- journal article
- Language
- en
- Open access
- closed
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