The DOI matches its Crossref record; 124 of the 124 references it cites were found in a registry or an index.
The Role of the Phosphorus Atom in Drug Design
Abstract
Although the phosphorus atom is found in a variety of oxidation states, most of the phosphorus‐containing molecules of pharmacological importance possess phosphorus in the form of phosphonate or phosphinate functional groups, or in a major oxidation state as a phosphate group. The most common occurrence of phosphorus in drugs is either in prodrugs or in compounds for which the phosphorus atom plays a role in the biological activity, such as in modified nucleotides, in metabolically stable analogues of metabolites bearing phosphate groups, and as bioisosteric analogues of carboxyl groups.
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Metadata
- Authors
- Rodriguez, J. B., & Gallo‐Rodriguez, C.
- Venue
- ChemMedChem
- Publisher
- Wiley
- Published
- 2019-01-11
- Volume
- 14
- Issue
- 2
- Pages
- 190-216
- ISSN
- 1860-7179 (ISSN-L)
- 1860-7187
- OpenAlex
- W2903791983
- Cited by
- 267
- References
- 124
- FWCI
- 4.40
- Type
- journal article
- Language
- en
- Open access
- closed
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