Cited by 141Cancer survivorship and careMindfulness and Compassion InterventionsChildhood Cancer Survivors' Quality of Life

The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index; 1 of the 20 sources its claims cite were checked for support.

Acceptance and commitment therapy for breast cancer survivors with fear of cancer recurrence: A 3-arm pilot randomized controlled trial.

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Abstract

Background: Fear of cancer recurrence (FCR) has a profound negative impact on quality of life (QOL) for many cancer survivors. Breast cancer survivors (BCS) are particularly vulnerable, with up to 70% reporting clinically significant FCR. To the authors' knowledge, evidence-based interventions for managing FCR are limited. Acceptance and commitment therapy (ACT) promotes psychological flexibility in managing life's stressors. The current study examined the feasibility and preliminary efficacy of group-based ACT for FCR in BCS.Methods: Post-treatment BCS (91 patients with stage I-III disease) with clinical FCR randomly were assigned to ACT (6 weekly 2-hour group sessions), survivorship education (SE; 6 weekly 2-hour group sessions), or enhanced usual care (EUC; one 30-minute group coaching session with survivorship readings). FCR severity (primary outcome) and avoidant coping, anxiety, post-traumatic stress, depression, QOL, and other FCR-related variables (secondary outcomes) were assessed at baseline (T1), after the intervention (T2), 1 month after the intervention (T3), and 6 months after the intervention (T4) using intent-to-treat analysis.Results: Satisfactory recruitment (43.8%) and retention (94.5%) rates demonstrated feasibility. Although each arm demonstrated within-group reductions in FCR severity over time, only ACT produced significant reductions at each time point compared with baseline, with between-group differences at T4 substantially favoring ACT over SE (Cohen d for effect sizes, 0.80; P < .001) and EUC (Cohen d, 0.61; P < .01). For 10 of 12 secondary outcomes, only ACT produced significant within-group reductions across all time points. By T4, significant moderate to large between-group comparisons favored ACT over SE and EUC with regard to avoidant coping, anxiety, depression, QOL, and FCR-related psychological distress.Conclusions: Group-based ACT is a feasible and promising treatment for FCR and associated outcomes in BCS that warrants testing in larger, fully powered trials.

Overview

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Crossref · 10.1002/cncr.32518

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    The observed recruitment (43.8%) and retention (94.5%) rates are satisfactory for demonstrating feasibility.

    “Satisfactory recruitment (43.8%) and retention (94.5%) demonstrated feasibility.”
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  1. Weiss D, 1997, Assessing Psychological Trauma and PTSD: A Practioner's Handbook, 339

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Metadata

Authors
Johns, S. A., Stutz, P. V., Talib, T. L., Cohee, A. A., Beck‐Coon, K. A., Brown, L. F., Wilhelm, L. R., Monahan, P. O., LaPradd, M. L., Champion, V. L., Miller, K. D., & Giesler, R. B.
Affiliations
  • Regenstrief Institute (US)
  • Indiana University Indianapolis (US)
  • West Virginia University (US)
  • Butler University (US)
Corresponding author
Johns, Shelley A.
Venue
Cancer
Publisher
Wiley
Published
2019-09-20
Volume
126
Issue
1
Pages
211-218
ISSN
  • 0008-543X (ISSN-L)
  • 1097-0142
OpenAlex
W2974123878
Cited by
141
References
43
Citations by year
2026: 18 · 2025: 20 · 2024: 19 · 2023: 25 · 2022: 29 · 2021: 21 · 2020: 8 · 2019: 1
FWCI
6.15
Type
journal article
Language
en
Open access
Locations
  • Cancer (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
  • IUScholarWorks (Indiana University) (submittedVersion)
Funders
  • Indiana University Health (0952)
  • National Cancer Institute (K05CA175048)
  • Walther Cancer Foundation (0175.01)
Topics
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
  • Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Childhood Cancer Survivors' Quality of Life
Keywords
acceptance and commitment therapy, fear of cancer recurrence, breast cancer survivors, group therapy, survivorship education, psychological flexibility, avoidance coping, anxiety, depression, post-traumatic stress, quality of life, psychological distress, feasibility
MeSH terms
Cancer Survivors, Involuntary Commitment, Adult, Aged, Anxiety, Breast, Breast Neoplasms, Depression, Fear, Female, Humans, Middle Aged, Neoplasm Recurrence, Local, Neoplasm Staging, Phobic Disorders, Quality of Life, Stress Disorders, Post-Traumatic

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