The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
Light‐microscopic immunocytochemical localization of tyrosine hydroxylase in prenatal rat brain. I. Early ontogeny
Abstract
The immunocytochemical localization of tyrosine hydroxylase is examined during ontogeny in the fetal rat brain in order to determine the age of first detection and subsequent cellular localization of the enzyme and the developmental characteristics of the immature catecholaminergic neurons. Fetal atlases of the tyrosine hydroxylase‐labeled neurons are presented at embryonic day (E) 12.5, 13.5, and 14.5. Tyrosine hydroxylase is first detected immunocytochemically at E 12.5. At this stage, the labeled neurons have completed final mitosis, but are still migrating and are cytologically immature. Tyrosine hydroxylase can also be detected in axons and axonal growth cones at this stage of development. The age of first immunocytochemical detection of the enzyme precedes the demonstration of catecholamine fluorescence by 1 to 2 days in certain nuclear groups. At later stages of development (E 13.5 and E 14.5), the major groups of perikarya and processes labeled for tyrosine hydroxylase have a distribution similar to that previously described by catecholamine fluorescence. At E 14.5, the perikarya undergo considerable changes in their cytology and exhibit the first dendrites immunocytochemically labeled for the enzyme. The first terminal fields are also detected in the rudimentary caudate‐putamen at this stage.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Dahlstroem, A., & Fuxé, K. (1964) · PubMed · Cited by 5,133
Stereotaxic mapping of the monoamine pathways in the rat brain
Ungerstedt, U. (1971) · Acta Physiologica Scandinavica · doi:10.1111/j.1365-201x.1971.tb10998.x · Cited by 3,819
Lindvall, O., & Björklund, A. (1974) · PubMed · Cited by 1,131
Demonstration and mapping out of nigro-neostriatal dopamine neurons
Andén, N.-E., Carlsson, A., Dahlström, A., Fuxe, K., Hillarp, N.-Å., & Larsson, K. (1964) · Life Sciences · doi:10.1016/0024-3205(64)90161-4 · Cited by 813
CATECHOLAMINES IN FETAL AND NEWBORN RAT BRAIN
Coyle, J. T., & Henry, D. (1973) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1973.tb04225.x · Cited by 781
Lauder, J. M., & Bloom, F. E. (1974) · Journal of Comparative Neurology · doi:10.1002/cne.901550407 · Cited by 655
Seiger, �., & Olson, L. (1973) · Zeitschrift f�r Anatomie und Entwicklungsgeschichte · doi:10.1007/bf00525058 · Cited by 650
Olson, L., & Seiger, �. (1972) · Zeitschrift f�r Anatomie und Entwicklungsgeschichte · doi:10.1007/bf00519099 · Cited by 501
Specht, L. A., Pickel, V. M., Joh, T. H., & Reis, D. J. (1981) · Journal of Comparative Neurology · doi:10.1002/cne.901990208 · Cited by 497
Self-citationSidman, R. L., Miale, I. L., & Feder, N. (1959) · Experimental Neurology · doi:10.1016/0014-4886(59)90024-x · Cited by 433
Cited by
Voorn, P., Kalsbeek, A., Jorritsma-Byham, B., & Groenewegen, H. J. (1988) · Neuroscience · doi:10.1016/0306-4522(88)90041-3 · Cited by 503
The endogenous cannabinoid system and brain development
Fernández-Ruiz, J., Berrendero, F., Hernández, M. L., & Ramos, J. A. (2000) · Trends in Neurosciences · doi:10.1016/s0166-2236(99)01491-5 · Cited by 347
Differentiation of Mesencephalic Progenitor Cells into Dopaminergic Neurons by Cytokines
Ling, Z. D., Potter, E. D., Lipton, J. W., & Carvey, P. M. (1998) · Experimental Neurology · doi:10.1006/exnr.1998.6715 · Cited by 295
Prenatal adverse effects of nicotine on the developing brain
(1988) · Progress in Brain Research · doi:10.1016/s0079-6123(08)60502-6 · Cited by 265
Puelles, L., Amat, J. A., & Martinez‐de‐la‐Torre, M. (1987) · Journal of Comparative Neurology · doi:10.1002/cne.902660210 · Cited by 261
Metadata
- Authors
- Specht, L. A., Pickel, V. M., Joh, T. H., & Reis, D. J.
- Venue
- Journal of Comparative Neurology
- Publisher
- Wiley
- Published
- 1981-06-20
- Volume
- 199
- Issue
- 2
- Pages
- 233-253
- ISSN
- 0021-9967 (ISSN-L)
- 1096-9861
- OpenAlex
- W4241399060
- Cited by
- 353
- References
- 34
- FWCI
- 3.61
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Light‐microscopic immunocytochemical localization of tyrosine hydroxylase in prenatal rat brain. I. Early ontogeny. https://app.cochat.ai/papers/10.1002/cne.901990207
- The paper
- Specht, L. A., Pickel, V. M., Joh, T. H., & Reis, D. J. (1981). Light‐microscopic immunocytochemical localization of tyrosine hydroxylase in prenatal rat brain. I. Early ontogeny. Journal of Comparative Neurology. https://doi.org/10.1002/cne.901990207
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
