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The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.

Lymphocyte Subset Counts in COVID‐19 Patients: A Meta‐Analysis

Open access
Huang, Wei, Berube, Julie, McNamara, Michelle, Saksena, Suraj, Hartman, Marsha, Arshad, Tariq, Bornheimer, Scott J., O'Gorman, Maurice·2020·Cytometry Part A

Abstract

A reduced peripheral blood absolute lymphocyte count with an elevated neutrophil count has been a consistent observation in hospitalized coronavirus disease 2019 (COVID‐19) patients. In this brief meta‐analysis, the reduction of lymphocyte subset counts in COVID‐19 patients was investigated across 20 peer‐reviewed studies meeting criteria for reporting lymphocyte subset counts and COVID‐19 disease severity. CD4+ T cell, CD8+ T cell, B cell, NK cell, and total lymphocyte cell counts all showed statistically significant reduction in patients with severe/critical COVID‐19 disease compared to mild/moderate disease. T‐cell subsets showed the largest standardized magnitude of change. In some studies, multivariate analysis has shown that CD4 and/or CD8 T‐cells counts are independently predictive of patient outcomes. © 2020 International Society for Advancement of Cytometry

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Metadata

Authors
Huang, W., Berube, J., McNamara, M., Saksena, S., Hartman, M., Arshad, T., Bornheimer, S. J., & O'Gorman, M.
Venue
Cytometry Part A
Publisher
Wiley
Published
2020-07-18
Volume
97
Issue
8
Pages
772-776
ISSN
  • 1552-4922 (ISSN-L)
  • 1552-4930
OpenAlex
W3034366532
Cited by
237
References
8
FWCI
5.76
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Lymphocyte Subset Counts in COVID‐19 Patients: A Meta‐Analysis. https://app.cochat.ai/papers/10.1002/cyto.a.24172
The paper
Huang, W., Berube, J., McNamara, M., Saksena, S., Hartman, M., Arshad, T., Bornheimer, S. J., & O'Gorman, M. (2020). Lymphocyte Subset Counts in COVID‐19 Patients: A Meta‐Analysis. Cytometry Part A. https://doi.org/10.1002/cyto.a.24172

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