Cited by 81Obsessive-Compulsive Spectrum DisordersPersonality Disorders and PsychopathologyAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Pilot trial of dialectical behavior therapy-enhanced habit reversal for trichotillomania

Open access
Keuthen, Nancy J., Rothbaum, Barbara O., Welch, Stacy Shaw, Taylor, Caitlin, Falkenstein, Martha, Heekin, Mary, Jordan, Cathrine Arndt, Timpano, Kiara +3 more·2010·Depression and Anxiety

Abstract

BACKGROUND: Not all hair pullers improve acutely with cognitive-behavioral treatment (CBT) and few maintain their gains over time. METHODS: We conducted an open clinical trial of a new treatment that addresses affectively triggered pulling and emphasizes relapse prevention in addition to standard CBT approaches. Ten female participants satisfying DSM-IV criteria for trichotillomania (TTM) at two study sites received Dialectical Behavior Therapy (DBT)-enhanced CBT consisting of 11 weekly sessions and 4 maintenance sessions over the following 3 months. Independent assessors rated hair pulling impairment and global improvement at several study time points. Participants completed self-report measures of hair pulling severity and emotion regulation. RESULTS: Significant improvement in hair pulling severity and emotion regulation, as well as hair pulling impairment and anxiety and depressive symptoms, occurred during acute treatment and were maintained during the subsequent 3 months. Significant correlations were reported between changes in emotion regulation and hair pulling severity during both the acute treatment and maintenance phases. CONCLUSIONS: This study offers preliminary evidence for the efficacy of DBT-enhanced CBT for TTM and suggests the importance of addressing emotion regulation during TTM treatment.

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  • Expected correlations between emotion regulation capacity and hair pulling severity were demonstrated during both acute and maintenance treatment.

    “Expected correlations between ER capacity and hair pulling severity were demonstrated during both acute and maintenance treatment.”

    From Dbt-enhanced cognitive-behavioral treatment for trichotillomania: A randomized controlled trial (2012) · cites this paper as Keuthen et al., 2010

    The Relationship Between TTM Severity and Emotion Regulation section (pp. 953–959) reports significant correlations between changes in emotion regulation and hair-pulling severity from pretreatment to posttreatment, and from pretreatment to three-month maintenance. It also says that none of the correlations for changes specifically between posttreatment and three-month maintenance were significant. Thus the acute-treatment finding is supported, but the wording overstates the finding during maintenance treatment. (LLM, conf=0.87)

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  • Open trial treatment resulted in significant improvement in TTM severity, emotion regulation capacity, experiential avoidance, anxiety and depression, with changes generally maintained over time.

    “Open trial treatment resulted in significant improvement in TTM severity, emotion regulation (ER) capacity, experiential avoidance, anxiety and depression with changes generally maintained over time.”

    From Dbt-enhanced cognitive-behavioral treatment for trichotillomania: A randomized controlled trial (2012) · cites this paper as Keuthen et al., 2010

    The Acute Treatment Outcomes and 3-Month Maintenance Outcomes sections report significant improvements in TTM severity, emotion regulation, anxiety, and depression that were generally maintained. They do not report experiential avoidance as an outcome of this open trial; the Introduction attributes that improvement to a separate wait-list-controlled study by Woods et al. (LLM, conf=0.91)

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  • In a pilot open treatment trial, DBT-enhanced habit reversal training produced significant improvement in hair pulling severity/impairment, emotion regulation and anxiety and depressive symptoms at both post-treatment and 3-month maintenance.

    “In a pilot open treatment trial of DBT-enhanced habit reversal training for TTM, we demonstrated significant improvement in hair pulling severity/impairment, ER and anxiety and depressive symptoms at both post-treatment and 3-month maintenance (Keuthen et al., 2010).”

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Research works printed but not linked: 5

  1. Flessner CA, Penzel F, Trichotillomania Learning Center Scientific Advisory Board & Keuthen NJ. Current treatment practices for children and adults with trichotillomania. Cogn Behav Pract 2010;17:290-300.
  2. Grant JE, Odlaug BL, King SW. N-acetylcysteine, a glutamate modulator, in the treatment of trichotillomania. Arch Gen Psychiatry 2009;66:756-763.
  3. Depression and Anxiety 15206394, 2010, 10, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/da.20732 by Mount Vernon Nazarene University, Wiley Online Library on [04/09/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License · DOI
  4. First MB, Spitzer RL, Gibbon M, Williams JBW. Structured Clinical Interview for DSM-IV Axis I Disorders: Patient Edition, (SCID-I/P, Version 2.0). New York: Biometrics Research Department; 1995.
  5. Beck AT, Steer RA, Brown GK. Beck Depression Inventory- Second Edition: Manual. San Antonio, TX: The Psychological Corporation; 1996.

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Authors
Keuthen, N. J., Rothbaum, B. O., Welch, S. S., Taylor, C., Falkenstein, M., Heekin, M., Jordan, C. A., Timpano, K., Meunier, S., Fama, J., & Jenike, M. A.
Affiliations
  • Harvard University (US)
  • Emory University (US)
  • University of Washington (US)
Corresponding author
Keuthen, Nancy J.
Venue
Depression and Anxiety
Published
2010-08-18
Volume
27
Issue
10
Pages
953-959
ISSN
1091-4269 (ISSN-L)
OpenAlex
W2160669132
Cited by
81
References
36
Citations by year
2026: 1 · 2025: 2 · 2024: 5 · 2023: 3 · 2022: 3 · 2021: 4 · 2020: 3 · 2019: 2 · 2018: 6 · 2017: 14 · 2016: 5 · 2015: 13 · 2014: 5 · 2013: 4 · 2012: 7
FWCI
5.26
Type
journal article
Language
en
Open access
Locations
  • Depression and Anxiety (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
  • Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
trichotillomania, dialectical behavior therapy, habit reversal, cognitive behavioral therapy, emotion regulation, hair pulling, relapse prevention, maintenance therapy, anxiety, depressive symptoms
MeSH terms
Adult, Emotions, Female, Habits, Humans, Pilot Projects, Psychiatric Status Rating Scales, Psychotropic Drugs, Severity of Illness Index, Trichotillomania, Cognitive Behavioral Therapy, Treatment Outcome

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