Cited by 54Cancer survivorship and careMental Health Treatment and AccessChildhood Cancer Survivors' Quality of Life

STRESSORS, SYMPTOM PROFILE, AND PREDICTORS OF ADJUSTMENT DISORDER IN CANCER PATIENTS. RESULTS FROM AN EPIDEMIOLOGICAL STUDY WITH THE COMPOSITE INTERNATIONAL DIAGNOSTIC INTERVIEW, ADAPTATION FOR ONCOLOGY (CIDI-O)

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Hund, Bianca, Reuter, Katrin, Härter, Martin, Brähler, Elmar, Faller, Hermann, Keller, Monika, Schulz, Holger, Wegscheider, Karl +5 more·2016·Depression and Anxiety

Abstract

BACKGROUND: We aimed to investigate type and frequency of stressors, predominant symptom profiles, and predictors of adjustment disorders (AD) in cancer patients across major tumor entities. METHODS: In this epidemiological study, we examined 2,141 cancer patients out of 4,020 screened with the Composite International Diagnostic Interview, adaptation for oncology (CIDI-O). AD were operationalized as subthreshold disorders according to DSM-IV criteria. RESULTS: In our sample, 265 out of 2,141 patients (12.4%) met all criteria for AD (unweighted 4-week prevalence). The disclosure of the cancer diagnosis, relapse or metastases, and cancer treatments were most frequently described as stressors associated with depressive or anxious symptoms. With regard to AD symptom profiles, patients showed high prevalence rates of affective symptoms according to the DSM-IV criteria of Major Depression: The highest prevalence rates were found for cognitive disturbances (concentration and memory problems) (88%), sleeping disturbances (86%), and depressive mood (83%). We found sex, education, and metastasis as significant predictors for AD. Higher education was the most influential predictor. Men were half as likely to report symptoms fulfilling the AD criteria as women. Patients with metastasized tumors had a more than 80% higher risk of AD than those without metastasis. However, the explained variance of our model is very small (Nagelkerke's R² = 0.08). CONCLUSIONS: Patients with AD can be identified using a standardized instrument and deserve clinical attention, as they often show severe clinical symptoms and impairments. Improving the clinical conceptualization of AD by the adding-on of potential stress-response-symptoms is necessary to identify severe psychological strain.

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  1. Mehnert A, Vehling S, Scheffold K, et al. Prävalenz von Anpas- sungsst örung, Akuter und Posttraumatischer Belastungsst örung sowie somatoformen St örungen bei Krebspatienten. Psychother Psychosom Med Psychol 2013;63:466-472.
  2. Baumeister H. Anpassungsst örungen im Sinne einer reaktiven De- pression. Psychosom Konsiliarpsychiatr 2008;2:92-97.

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Authors
Hund, B., Reuter, K., Härter, M., Brähler, E., Faller, H., Keller, M., Schulz, H., Wegscheider, K., Weis, J., Wittchen, H.-U., Koch, U., Friedrich, M., & Mehnert, A.
Affiliations
  • University Medical Center Freiburg (DE)
  • University Medical Center Hamburg-Eppendorf (DE)
  • University Hospital Leipzig (DE)
  • University of Würzburg (DE)
  • University Hospital Heidelberg (DE)
  • University of Freiburg (DE)
  • Institute of Clinical Psychology and Psychotherapy and Center of Clinical Epidemiology and Longitudinal Studies (CELOS); Technical University Dresden; Dresden Germany
Corresponding author
Mehnert, Anja
Venue
Depression and Anxiety
Published
2015-10-16
Volume
33
Issue
2
Pages
153-161
ISSN
1091-4269 (ISSN-L)
OpenAlex
W2154222677
Cited by
54
References
28
Citations by year
2026: 3 · 2025: 5 · 2024: 4 · 2023: 6 · 2022: 5 · 2021: 7 · 2020: 5 · 2019: 5 · 2018: 2 · 2017: 7 · 2016: 5
FWCI
2.04
Type
journal article
Language
en
Open access
Locations
  • Depression and Anxiety (publishedVersion)
  • PubMed (publishedVersion)
Funders
Deutsche Krebshilfe (107465)
Topics
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
  • Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Childhood Cancer Survivors' Quality of Life
Keywords
adjustment disorder, cancer patients, psychological stressors, symptom profiles, depressive symptoms, anxiety symptoms, cognitive disorders, sleep disorders, metastasis, sex differences, educational attainment, psychological strain
MeSH terms
Adjustment Disorders, Adolescent, Adult, Aged, Cross-Sectional Studies, Female, Germany, Humans, Male, Middle Aged, Neoplasms, Psychiatric Status Rating Scales, Prevalence, Epidemiologic Studies, Young Adult

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