Cited by 102Dementia and Cognitive Impairment ResearchPsychological Testing and AssessmentCognitive Abilities and Testing

Lower practice effects as a marker of cognitive performance and dementia risk: a literature review

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Jutten, Roos J., Grandoit, Evan, Foldi, Nancy S., Sikkes, Sietske A. M., Jones, Richard N., Choi, Seo‐Eun, Lamar, Melissa L., Louden, Diana K. N. +4 more·2020·Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring

Abstract

BACKGROUND: Practice effects (PEs) are improvements in performance after repeated exposure to test materials, and typically viewed as a source of bias in repeated cognitive assessments. We aimed to determine whether characterizing PEs could also provide a useful marker of early cognitive decline. METHODS: We conducted a systematic review of the literature, searching PsycInfo (Ebsco) and PubMed databases for articles studying PEs in aging and dementia populations. Articles published between 1920 and 2019 were included. RESULT: We identified 259 articles, of which 27 studied PEs as markers of cognitive performance. These studies consistently showed that smaller, less-robust PEs were associated with current diagnostic status and/or future cognitive decline. In addition, lower PEs were associated with Alzheimer's disease risk factors and neurodegeneration biomarkers. CONCLUSION: PEs provide a potentially useful marker of cognitive decline, and could prove valuable as part of a cost-effective strategy to select individuals who are at-risk for dementia for future interventions.

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Authors
Jutten, R. J., Grandoit, E., Foldi, N. S., Sikkes, S. A. M., Jones, R. N., Choi, S., Lamar, M. L., Louden, D. K. N., Rich, J., Tommet, D., Crane, P. K., & Rabin, L. A.
Affiliations
  • Amsterdam Neuroscience (NL)
  • Northwestern University (US)
  • Queens College, CUNY (US)
  • Brown University (US)
  • University of Washington (US)
  • Rush University Medical Center (US)
  • University Libraries, University of Washington Seattle Washington USA
  • City University of New York (US)
Corresponding author
Jutten, Roos J.
Venue
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
Publisher
Wiley
Published
2020-01
Volume
12
Issue
1
Pages
e12055-e12055
ISSN
2352-8729 (ISSN-L)
OpenAlex
W3041514621
Cited by
102
References
55
Citations by year
2026: 8 · 2025: 25 · 2024: 16 · 2023: 16 · 2022: 18 · 2021: 16 · 2020: 3
FWCI
9.67
Type
journal article
Language
en
Open access
Locations
  • Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring (publishedVersion, cc-by-nc-nd)
  • PubMed Central (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
  • VU Research Portal (publishedVersion, other-oa)
  • CUNY Academic Works (City University of New York) (submittedVersion, cc-by-nc-nd)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • Pure Amsterdam UMC (submittedVersion, other-oa)
  • Amsterdam UMC (VU Amsterdam) - Institutional Repository (submittedVersion, other-oa)
  • Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
Funders
  • National Institutes of Health
  • National Institute on Aging (R01AG029672, U19AG066567)
  • National Institute of General Medical Sciences (SC3GM122662)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Social Sciences › Psychology › Applied Psychology › Psychological Testing and Assessment
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Abilities and Testing
Keywords
practice effects, cognitive decline, dementia risk, Alzheimer's disease, neurodegeneration biomarkers, aging, cognitive performance, dementia risk prediction

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