Reliable change in cognition over 1 week in community-dwelling older adults: a validation and extension study
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Objective: Reliable change methods can aid neuropsychologists in understanding if performance differences over time represent clinically meaningful change or reflect benefit from practice. The current study sought to externally validate the previously published standardized regression-based (SRB) prediction equations developed by Duff for commonly administered cognitive measures. Method: This study applied Duff’s SRB prediction equations to an independent sample of community-dwelling participants with amnestic mild cognitive impairment (MCI) assessed twice over a 1-week period. A comparison of MCI subgroups (e.g., single v. multi domain) on the amount of change observed over 1 week was also examined. Results: Using pairwise t-tests, large and statistically significant improvements were observed on most measures across 1 week. However, the observed follow-up scores were consistently below expectation compared with predictions based on Duff’s SRB algorithms. In individual analyses, a greater percentage of MCI participants showed smaller-than-expected practice effects based on normal distributions. In secondary analyses, smaller-than-expected practice effects were observed in participants with worse baseline memory impairment and a greater number of impaired cognitive domains, particularly for measures of executive functioning/speeded processing. Conclusions: These findings help to further support the validity of Duff’s 1-week SRB prediction equations in MCI samples and extend previous research by showing incrementally smaller-than-expected benefit from practice for increasingly impaired amnestic MCI subtypes.
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Individuals with aMCI typically demonstrate attenuated practice effects.
“individuals with aMCI typically demonstrate attenuated practice effects [54,55]”
From A phase I trial of accelerated intermittent theta burst rTMS for amnestic MCI (2024) · cites this paper as [54]
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Practice effects predict cognitive outcome in amnestic mild cognitive impairment
Duff, K., Lyketsos, C. G., Beglinger, L. J., Chelune, G., Moser, D. J., Arndt, S., Schultz, S. K., Paulsen, J. S., Petersen, R. C., & McCaffrey, R. J. (2011) · The American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e318209dd3a · Cited by 126 · see citing works
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Cited by
Sorted by citations
Lower practice effects as a marker of cognitive performance and dementia risk: a literature review
Jutten, R. J., Grandoit, E., Foldi, N. S., Sikkes, S. A. M., Jones, R. N., Choi, S., Lamar, M. L., Louden, D. K. N., Rich, J., Tommet, D., et al. (2020) · Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring · doi:10.1002/dad2.12055 · Cited by 102 · see citing works
A phase I trial of accelerated intermittent theta burst rTMS for amnestic MCI
Aghamoosa, S., Lopez, J., Rbeiz, K., Fleischmann, H. H., Horn, O., Madden, K., Caulfield, K. A., Antonucci, M. U., Revuelta, G., McTeague, L. M., et al. (2024) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp-2023-332680 · Cited by 12 · see citing works
- Authors
- Hammers, D. B., Suhrie, K. R., Dixon, A., Porter, S., & Duff, K.
- Affiliations
- University of Utah (US)
- Corresponding author
- Hammers, Dustin B
- Venue
- Archives of Clinical Neuropsychology
- Publisher
- Oxford University Press (OUP)
- Published
- 2020-02-06
- Volume
- 36
- Issue
- 3
- Pages
- 347-358
- ISSN
- 0887-6177 (ISSN-L)
- 1873-5843
- PMC
- PMC8245079
- OpenAlex
- W3005370886
- Cited by
- 12
- References
- 1
- Citations by year
- 2026: 1 · 2024: 3 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 4
- FWCI
- 1.39
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- public-domain
- Locations
- Archives of Clinical Neuropsychology (publishedVersion, public-domain)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- IUScholarWorks (Indiana University) (submittedVersion, public-domain)
- Funders
- National Institute on Aging (5R01AG045163)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Social Sciences › Psychology › Applied Psychology › Psychological Testing and Assessment
- Social Sciences › Psychology › Clinical Psychology › Historical and Modern Theater Studies
- Keywords
- reliable change, practice effects, amnestic mild cognitive impairment, memory impairment, executive function, processing speed, community-dwelling older adults
- MeSH terms
- Aged, Cognition, Humans, Neuropsychological Tests, Executive Function, Independent Living, Cognitive Dysfunction
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