The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
gfap and nestin reporter lines reveal characteristics of neural progenitors in the adult zebrafish brain
Open accessAbstract
Adult neurogenesis arises from niches that harbor neural stem cells (NSC). Although holding great promise for regenerative medicine, the identity of NSC remains elusive. In mammals, a key attribute of NSC is the expression of the filamentous proteins glial fibrillary acidic protein (GFAP) and NESTIN. To assess whether these two markers are relevant in the fish model, two transgenic zebrafish lines for gfap and nestin were generated. Analysis of adult brains showed that the fusion GFAP–green fluorescent protein closely mimics endogenous GFAP, while the nestin transgene recapitulates nestin at the ventricular zones. Cells expressing the two reporters display radial glial morphology, colocalize with the NSC marker Sox2, undergo proliferation, and are capable of self‐renewal within the matrix of distinct thickness in the telencephalon. Together, these two transgenic lines reveal a conserved feature of putative NSC in the adult zebrafish brain and provide a means for the identification and manipulation of these cells in vivo. Developmental Dynamics 238:475–486, 2009. © 2009 Wiley‐Liss, Inc.
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Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
Doetsch, F., Caillé, I., Lim, D. A., García-Verdugo, J. M., & Alvarez-Buylla, A. (1999) · Cell · doi:10.1016/s0092-8674(00)80783-7 · Cited by 3,898
Kuhn, H., Dickinson-Anson, H., & Gage, F. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-06-02027.1996 · Cited by 3,139
Grandel, H., Kaslin, J., Ganz, J., Wenzel, I., & Brand, M. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2006.03.040 · Cited by 598
Cited by
Neurogenesis in zebrafish – from embryo to adult
Schmidt, R., Strähle, U., & Scholpp, S. (2013) · Neural Development · doi:10.1186/1749-8104-8-3 · Cited by 375
Self-citationAdult neurogenesis and brain regeneration in zebrafish
Kizil, C., Kaslin, J., Kroehne, V., & Brand, M. (2012) · Developmental Neurobiology · doi:10.1002/dneu.20918 · Cited by 349
Fgf-Dependent Glial Cell Bridges Facilitate Spinal Cord Regeneration in Zebrafish
Goldshmit, Y., Sztal, T. E., Jusuf, P. R., Hall, T. E., Nguyen-Chi, M., & Currie, P. D. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.0758-12.2012 · Cited by 274
Glial Cells as Progenitors and Stem Cells: New Roles in the Healthy and Diseased Brain
Dimou, L., & Götz, M. (2014) · Physiological Reviews · doi:10.1152/physrev.00036.2013 · Cited by 264
Chapouton, P., Skupien, P., Hesl, B., Coolen, M., Moore, J. C., Madelaine, R., Kremmer, E., Faus-Kessler, T., Blader, P., Lawson, N. D., et al. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.6170-09.2010 · Cited by 259
Metadata
- Authors
- Lam, C. S., März, M., & Strähle, U.
- Venue
- Developmental Dynamics
- Publisher
- Wiley
- Published
- 2009-01-22
- Volume
- 238
- Issue
- 2
- Pages
- 475-486
- ISSN
- 1058-8388 (ISSN-L)
- 1097-0177
- OpenAlex
- W1983461332
- Cited by
- 184
- References
- 3
- FWCI
- 3.78
- Type
- journal article
- Language
- en
- Open access
- bronze
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