Designing Meaningful Outcome Parameters Using Mobile Technology: A New Mobile Application for Telemonitoring of Patients with Heart Failure
Open accessAbstract
Aims: Health data captured by commercially available smart devices may represent meaningful patient-reported outcome measures (PROMs) in heart failure (HF) patients. The purpose of this study was to test this hypothesis by evaluating the feasibility of a new telemonitoring concept for patients following initial HF hospitalization. Methods and results: We designed a cardio patient monitoring platform (CPMP) that comprised mobile iOS-based applications for patients' smartphone/smartwatch and the equivalent application on a physicians' tablet. It allowed for safe and continuous data transmission of self-measured physiological parameters, activity data, and patient-reported symptoms. In a prospective feasibility trial with 692 patient days from 10 patients hospitalized for newly diagnosed HF with reduced ejection fraction (mean left ventricular ejection fraction (LVEF) 26.5 ± 9.8%), we examined the CPMP during the first 2 months following discharge (69 ± 15 observation days per patient). The mean daily step count recorded by the mobile devices emerged as a promising new PROM. Its 14 day average increased over the study period (3612 ± 3311 steps/day at study inclusion and 7069 ± 5006 steps/day at end of study; P < 0.0001). It is unique for continuously reflecting real-life activity and correlated significantly with traditional surrogate parameters of cardiac performance including LVEF (r = 0.44; 95% CI 0.07–0.71; P = 0.0232), 6 min walk test (r = 0.67; 95% CI 0.38–0.84; P = 0.0002), and scores in health-related quality of life questionnaires. Conclusions: We provide the first patient monitoring platform for HF patients that relies on commercially available iOS/watchOS-based devices. Our study suggests it is ready for implementation as a tool for recording meaningful PROMs in future HF trials and telemonitoring.
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Administering the 6-minute walk test through a pedometer is feasible and can be used to predict HF severity and death.
“For example, one study showed that administering the 6-minute walk test through a pedometer is feasible and can be used to predict HF severity and death62.”
From Smart wearable devices in cardiovascular care: Where we are and how to move forward (2021) · cites this paper as [62]
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Smart wearable devices in cardiovascular care: Where we are and how to move forward
Bayoumy, K., Gaber, M., Elshafeey, A., Mhaimeed, O., Dineen, E. H., Marvel, F. A., Martin, S. S., Muse, E. D., Turakhia, M. P., Tarakji, K. G., et al. (2021) · Nature Reviews Cardiology · doi:10.1038/s41569-021-00522-7 · Cited by 829 · see citing works
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- Authors
- Werhahn, S. M., Dathe, H., Rottmann, T., Franke, T., Vahdat, D., Hasenfuß, G., & Seidler, T.
- Affiliations
- Universitätsmedizin Göttingen (DE)
- Medopad Ltd , London ,
- Corresponding author
- Seidler, Tim
- Venue
- ESC Heart Failure
- Publisher
- Oxford University Press (OUP)
- Published
- 2019-03-13
- Volume
- 6
- Issue
- 3
- Pages
- 516-525
- ISSN
- 2055-5822 (ISSN-L)
- PMC
- PMC6487706
- OpenAlex
- W2921688314
- Cited by
- 59
- References
- 31
- Citations by year
- 2026: 1 · 2025: 5 · 2024: 8 · 2023: 7 · 2022: 14 · 2021: 15 · 2020: 7 · 2019: 2
- FWCI
- 12.94
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- ESC Heart Failure (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- GoeScholar The Publication Server of the Georg-August-Universität Göttingen (Georg-August-Universität Göttingen) (submittedVersion, cc-by-nc-nd)
- Funders
- Department of Cardiology of the University Medical Center Göttingen
- Topics
- Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Telemedicine and Telehealth Implementation
- Keywords
- heart failure, remote patient monitoring, patient-reported outcome measures, mobile health, step count, left ventricular ejection fraction, health-related quality of life, post-discharge monitoring, wearable devices, smartwatches, 6-minute walk test
- MeSH terms
- Wearable Electronic Devices, Adult, Feasibility Studies, Female, Heart Failure, Humans, Male, Middle Aged, Prospective Studies, Quality of Life, Treatment Outcome, Telemedicine, Monitoring, Ambulatory, Mobile Applications
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