Effects of person-centred and integrated chronic heart failure and palliative home care. PREFER: a randomized controlled study
Abstract
AIMS: We evaluated the outcome of person-centred and integrated Palliative advanced home caRE and heart FailurE caRe (PREFER) with regard to patient symptoms, health-related quality of life (HQRL), and hospitalizations compared with usual care. METHODS AND RESULTS: From January 2011 to October 2012, 36 (26 males, 10 females, mean age 81.9 years) patients with chronic heart failure (NYHA class III-IV) were randomized to PREFER and 36 (25 males, 11 females, mean age 76.6 years) to the control group at a single centre. Prospective assessments were made at 1, 3, and 6 months using the Edmonton Symptom Assessment Scale, Euro Qol, Kansas City Cardiomyopathy Questionnaire, and rehospitalizations. Between-group analysis revealed that patients receiving PREFER had improved HRQL compared with controls (57.6 ± 19.2 vs. 48.5 ± 24.4, age-adjusted P-value = 0.05). Within-group analysis revealed a 26% improvement in the PREFER group for HRQL (P = 0.046) compared with 3% (P = 0.82) in the control group. Nausea was improved in the PREFER group (2.4 ± 2.7 vs. 1.7 ± 1.7, P = 0.02), and total symptom burden, self-efficacy, and quality of life improved by 18% (P = 0.035), 17% (P = 0.041), and 24% (P = 0.047), respectively. NYHA class improved in 11 of the 28 (39%) PREFER patients compared with 3 of the 29 (10%) control patients (P = 0.015). Fifteen rehospitalizations (103 days) occurred in the PREFER group, compared with 53 (305 days) in the control group. CONCLUSION: Person-centred care combined with active heart failure and palliative care at home has the potential to improve quality of life and morbidity substantially in patients with severe chronic heart failure. TRIAL REGISTRATION: NCT01304381.
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In the months prior to death, cancer patients receive more frequent palliative care consultations and symptom-directed prescriptions and report a lower impact of symptoms than those with CHF.
“yet in the months prior to death, cancer patients receive more frequent palliative care consultations and symptom‐directed prescriptions and report a lower impact of symptoms than those with CHF. 13”
From Prioritizing symptom management in the treatment of chronic heart failure (2020) · cites this paper as [13]
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- Authors
- Brännström, M., & Boman, K.
- Affiliations
- Umeå University (SE)
- Corresponding author
- Brännström, Margareta
- Venue
- European Journal of Heart Failure
- Publisher
- Oxford University Press (OUP)
- Published
- 2014-08-27
- Volume
- 16
- Issue
- 10
- Pages
- 1142-1151
- ISSN
- 1388-9842 (ISSN-L)
- 1879-0844
- OpenAlex
- W2116480815
- Cited by
- 356
- References
- 31
- Citations by year
- 2026: 23 · 2025: 26 · 2024: 35 · 2023: 24 · 2022: 36 · 2021: 35 · 2020: 47 · 2019: 33 · 2018: 30 · 2017: 28 · 2016: 24 · 2015: 14
- FWCI
- 21.79
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Heart Failure (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Swedish Association of Local Authorities and Regions
- Swedish Heart and Lung Association
- Ronnbaret Foundation Skelleftea Municipality
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
- Health Sciences › Health Professions › General Health Professions › Geriatric Care and Nursing Homes
- Keywords
- chronic heart failure, palliative care, home care, person-centred care, integrated care, health-related quality of life, symptom burden, hospital readmission, NYHA functional class, self-efficacy, advanced heart failure
- MeSH terms
- Aged, Aged, 80 and over, Chronic Disease, Female, Heart Failure, Home Care Services, Hospitalization, Humans, Male, Palliative Care, Quality of Life, Sweden, Outcome Assessment, Health Care, Patient-Centered Care, Delivery of Health Care, Integrated
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