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European Society of Cardiology Heart Failure Long-Term Registry (ESC-HF-LT): 1-Year Follow-Up Outcomes and Differences Across Regions
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Aims: The European Society of Cardiology Heart Failure Long-Term Registry (ESC-HF-LT-R) was set up with the aim of describing the clinical epidemiology and the 1-year outcomes of patients with heart failure (HF) with the added intention of comparing differences between participating countries. Methods and results: The ESC-HF-LT-R is a prospective, observational registry contributed to by 211 cardiology centres in 21 European and/or Mediterranean countries, all being member countries of the ESC. Between May 2011 and April 2013 it collected data on 12 440 patients, 40.5% of them hospitalized with acute HF (AHF) and 59.5% outpatients with chronic HF (CHF). The all-cause 1-year mortality rate was 23.6% for AHF and 6.4% for CHF. The combined endpoint of mortality or HF hospitalization within 1 year had a rate of 36% for AHF and 14.5% for CHF. All-cause mortality rates in the different regions ranged from 21.6% to 36.5% in patients with AHF, and from 6.9% to 15.6% in those with CHF. These differences in mortality between regions are thought reflect differences in the characteristics and/or management of these patients. Conclusion: The ESC-HF-LT-R shows that 1-year all-cause mortality of patients with AHF is still high while the mortality of CHF is lower. This registry provides the opportunity to evaluate the management and outcomes of patients with HF and identify areas for improvement.
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“Each increment of 1 unit in the risk score is associated with a 24% higher HF risk within 5 years.”
From 2023 ESC guidelines for the management of cardiovascular disease in patients with diabetes. (2023) · cites this paper as [480]
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“20,25) However, in the Danish nationwide cohort study, the 1-year mortality rate was 33% and the 5-year mortality rate was 43% in patients with a first hospitalization for HF. 15) In the United States GWTG-HF registry, the 5-year mortality rate was 75.4%, which was much higher than that in our…”
InfluentialThe Difference in Referencing in Web of Science, Scopus, and Google Scholar
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Digital Health: Implications for Heart Failure Management
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“This document defines 12 main and 4 secondary QIs across five domains of care for the management of HF: (1) structural framework, (2) patient assessment, (3) initial treatment, (4) therapy optimization, and (5) assessment of patient health-related quality of life.”
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Ganapathi, S., Jeemon, P., Agarwal, A., Viswanathan, S. K., Sreedharan, M., Vijayaraghavan, G., Bahuleyan, C. G., Biju, R., Nair, T., Prathapkumar, N., et al. (2018) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2018.05.007 · Cited by 59
Therapeutic and Prognostic Significance of Arachidonic Acid in Heart Failure
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“lationship between clinical, biochemical, and echocardiographic parameters and mortality in patients admitted with AHF, and our results contribute to reinforce and extend these.(1,5) Contrary to the literature, we found more daytime hospitalization for AHF than night-time.”
BackgroundResultSelf-citation2026 ESC Guidelines for the management of heart failure
Køber, L., Adamo, M., Ruwald, A., Tomasoni, D., Anderson, L., Andersson, C., Brugts, J. J., Chioncel, O. D., Donal, E., Ferdinandy, P., et al. (2026) · European Heart Journal · doi:10.1093/eurheartj/ehag100 · Cited by 109
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Self-citationImplementing Guideline-Directed Medical Therapy for Heart Failure
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Fatigue in heart failure outpatients: levels, associated factors, and the impact on quality of life
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Chinese Guidelines for the Diagnosis and Treatment of Heart Failure 2024
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“and outcomes for these patients are still poor(4,5): hospitalization for acute HF is associated with higher mortality, recurrent hospitalization, and increased resource consumption.(4,6)”
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Self-citationCancer and Heart Failure—More than Meets the Eye: Common Risk Factors and Co-Morbidities
Anker, M. S., von Haehling, S., Landmesser, U., Coats, A. J. S., & Anker, S. D. (2018) · European Journal of Heart Failure · doi:10.1002/ejhf.1252 · Cited by 52
Self-citationDrug Layering in Heart Failure
Rosano, G. M. C., Allen, L. A., Abdin, A., Lindenfeld, J. M., O’Meara, E., Lam, C. S. P., Lancellotti, P., Savarese, G., Gottlieb, S. S., Teerlink, J. R., et al. (2021) · JACC Heart Failure · doi:10.1016/j.jchf.2021.06.011 · Cited by 50
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Metadata
- Authors
- Crespo-Leiro, M. G., Anker, S. D., Maggioni, A. P., Coats, A. J., Filippatos, G., Ruschitzka, F., Ferrari, R., Piepoli, M. F., Delgado Jimenez, J. F., Metra, M., Fonseca, C., Hradec, J., Amir, O., Logeart, D., Dahlström, U., Merkely, B., Drozdz, J., Goncalvesova, E., Hassanein, M., Chioncel, O., Lainscak, M., Seferovic, P. M., Tousoulis, D., Kavoliuniene, A., Fruhwald, F., Fazlibegovic, E., Temizhan, A., Gatzov, P., Erglis, A., Laroche, C., & Mebazaa, A.
- Affiliations
- Unidad de Insuficiencia Cardiaca Avanzada y Trasplante Cardiaco, Complexo Hospitalario Universitario A Coruna, CHUAC , La Coruna ,
- Universitätsmedizin Göttingen (DE)
- European Society of Cardiology (FR)
- University of Warwick (GB)
- University General Hospital Attikon (GR)
- University of Zurich (CH)
- University of Ferrara (IT)
- Azienda Unità Sanitaria Locale Piacenza (IT)
- Cardiology Department, University Hospital 12 de Octubre , Madrid ,
- University of Brescia (IT)
- Heart Failure Unit, S Francisco Xavier Hospital/CHLO NOVA Medical School, Faculdade de Ciências Medicas, Universidade Nova de Lisboa
- Charles University (CZ)
- Bar-Ilan University (IL)
- Inserm (FR)
- Linköping University (SE)
- Semmelweis University, Heart Centre , Budapest ,
- Department of Cardiology, Medical University of Lodz , Lodz ,
- Department of Heart Failure/Transplantation, National Cardiovascular Institute , Bratislava ,
- Alexandria University (EG)
- Carol Davila University of Medicine and Pharmacy (RO)
- Department of Cardiology, General Hospital Celje , Celje ,
- University of Belgrade (RS)
- National and Kapodistrian University of Athens (GR)
- Department of Cardiology, Lithuanian University of Health Sciences , Kaunas ,
- Medical University of Graz (AT)
- Department of Internal Medicine, Clinical Hospital Mostar, Mostar, Bosnia and Herzegovina
- Türkiye Yüksek İhtisas Hastanesi (TR)
- Lozenetz Hospital (BG)
- Pauls Stradins Clinical University Hospital , Riga ,
- ORCID
- Venue
- European Journal of Heart Failure
- Publisher
- Oxford University Press (OUP)
- Published
- 2016-06-01
- Volume
- 18
- Issue
- 6
- Pages
- 613-625
- ISSN
- 1388-9842 (ISSN-L)
- 1879-0844
- OpenAlex
- W2465883722
- Cited by
- 798
- References
- 26
- Citations by year
- 2026: 54 · 2025: 88 · 2024: 88 · 2023: 108 · 2022: 97 · 2021: 79 · 2020: 92 · 2019: 61 · 2018: 65 · 2017: 52 · 2016: 13
- FWCI
- 52.52
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- European Journal of Heart Failure (publishedVersion)
- PubMed (publishedVersion)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (acceptedVersion)
- Zurich Open Repository and Archive (University of Zurich) (acceptedVersion)
- Monash University Research Portal (Monash University) (submittedVersion, other-oa)
- Institutional Research Information System (Università degli Studi di Brescia) (submittedVersion)
- Archivio Istituzionale della Ricerca - Università Vita-Salute San Raffaele (submittedVersion)
- Lithuanian University of Health Sciences (submittedVersion)
- RUC (Universidade Da Coruña) (submittedVersion)
- Institutional Research Information System University of Ferrara (University of Ferrara) (submittedVersion, other-oa)
- Zurich Open Repository and Archive (University of Zurich) (submittedVersion)
- Funders
- ESC.
- Abbott Vascular International (2011-2014)
- Amgen (2012-2015)
- AstraZeneca (2014-2017)
- Bayer (2013-2018)
- Boehringer Ingelheim (2013-2016)
- Boston Scientific (2010-2012)
- The Bristol Myers Squibb
- Pfizer Alliance (2014-2016)
- The Alliance Daiichi Sankyo Europe GmbH
- Eli Lilly and Company (2014-2017)
- Gedeon Richter Plc. (2014-2017)
- Menarini Int. Op. (2010-2012)
- MSD-Merck and Co. (2011-2014)
- Novartis Pharma AG (2014-2017)
- ResMed (2014-2016)
- Sanofi (2010-2011)
- SERVIER (2012-2015)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart rate and cardiovascular health
- Keywords
- heart failure, acute heart failure, chronic heart failure, all-cause mortality, one-year outcomes, heart failure hospitalization, regional variation in mortality, clinical epidemiology
- MeSH terms
- Acute Disease, Aged, Aged, 80 and over, Ambulatory Care, Cardiology, Cause of Death, Chronic Disease, Europe, Female, Follow-Up Studies, Heart Failure, Hospitalization, Humans, Male, Middle Aged, Mortality, Prospective Studies, Registries, Societies, Medical, Comorbidity
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