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Cited by 280

The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.

Cloning of TRAP, a ligand for CD40 on human T cells

Graf, Daniel, Korthäuer, Ulf, Mages, Hans W., Senger, Gabriele, Kroczek, Richard A.·1992·European Journal of Immunology

Abstract

A cDNA clone, designated TRAP (TNF‐related activation protein) was isolated from a collection of T cell activation genes. The polypeptide encoded by a mRNA of approx. 2.3 kb is 261 amino acids long with a calculated M r of 29.3 kDa. The structural features predict a type II transmembrane protein, but are also compatible with a secreted form. TRAP is highly similar to an identified murine CD40 ligand both at the cDNA (82.8% identity) and the protein (77.4% identity) levels, and related to tumor necrosis factor/lymphotoxin. Expressed in a murine myeloma, TRAP was identified as a ligand for CD40 by binding to a soluble CD40 construct. TRAP mRNA is expressed in a T cell‐specific fashion with a maximum at 8 h after stimulation. The TRAP gene is located in the q26.3–q27.1 region of the X chromosome.

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Metadata

Authors
Graf, D., Korthäuer, U., Mages, H. W., Senger, G., & Kroczek, R. A.
Venue
European Journal of Immunology
Publisher
Wiley
Published
1992-12
Volume
22
Issue
12
Pages
3191-3194
ISSN
  • 0014-2980 (ISSN-L)
  • 1521-4141
OpenAlex
W1987653378
Cited by
280
References
18
FWCI
12.70
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Cloning of TRAP, a ligand for CD40 on human T cells. https://app.cochat.ai/papers/10.1002/eji.1830221226
The paper
Graf, D., Korthäuer, U., Mages, H. W., Senger, G., & Kroczek, R. A. (1992). Cloning of TRAP, a ligand for CD40 on human T cells. European Journal of Immunology. https://doi.org/10.1002/eji.1830221226

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.