The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Nanoscale Metal–Organic Frameworks: Magnetic Resonance Imaging Contrast Agents and Beyond
Abstract
Magnetic resonance imaging (MRI) is an imaging technique based on the detection of nuclear spin reorientations in a magnetic field. MRI provides high spatial resolution and soft‐tissue contrast in anatomical images, and a large penetration depth; however, it is relatively insensitive and typically relies on large doses of administered contrast agents to give adequate contrast between normal and diseased tissues. This review covers the development of nanoscale metal–organic frameworks (NMOFs) as novel MRI contrast agents. NMOFs not only provide an effective vehicle for delivering large amounts of paramagnetic metal centers but also exhibit enhanced per‐metal‐based relaxivity relative to clinically used small‐molecule contrast agents. The in vitro and in vivo effectiveness of these agents has also been demonstrated. The potential of NMOFs as contrast agents for other imaging modalities, such as optical imaging (OI) and X‐ray computed tomography (CT), and as chemical and biological sensors is also discussed.
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Cites
Nanocarriers as an emerging platform for cancer therapy
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Factors affecting the clearance and biodistribution of polymeric nanoparticles
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Cited by
Yusuf, V. F., Malek, N. I., & Kailasa, S. K. (2022) · ACS Omega · doi:10.1021/acsomega.2c05310 · Cited by 894
Applications of magnetic metal–organic framework composites
Ricco, R., Malfatti, L., Takahashi, M., Hill, A. J., & Falcaro, P. (2013) · Journal of Materials Chemistry A · doi:10.1039/c3ta13140h · Cited by 316
Hybrid nanoparticles for combination therapy of cancer
He, C., Lu, J., & Lin, W. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.09.029 · Cited by 174
Self-citation
Metadata
- Authors
- Della Rocca, J., & Lin, W.
- Venue
- European Journal of Inorganic Chemistry
- Publisher
- Wiley
- Published
- 2010-07-07
- Volume
- 2010
- Issue
- 24
- Pages
- 3725-3734
- ISSN
- 1099-0682 (ISSN-L)
- 1434-1948
- OpenAlex
- W2029432014
- Cited by
- 203
- References
- 5
- FWCI
- 13.59
- Type
- journal article
- Language
- en
- Open access
- closed
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