Hybrid nanoparticles for combination therapy of cancer

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Cancer Cell Imaging and Photothermal Therapy in the Near-Infrared Region by Using Gold Nanorods

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Hydrogen Storage in Metal–Organic Frameworks

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Photodynamic therapy and anti-tumour immunity

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Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers☆

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Mechanisms of Cancer Drug Resistance

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Crystal Engineering of NLO Materials Based on Metal−Organic Coordination Networks

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Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization

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Metal–organic frameworks for artificial photosynthesis and photocatalysis

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Nanoscale Metal–Organic Frameworks for Biomedical Imaging and Drug Delivery

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Hydrogel nanoparticles in drug delivery

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Hydrocarbon Separations in a Metal-Organic Framework with Open Iron(II) Coordination Sites

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Activatable Photosensitizers for Imaging and Therapy

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Pharmacokinetics and Biodistribution of Nanoparticles

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Doping Metal–Organic Frameworks for Water Oxidation, Carbon Dioxide Reduction, and Organic Photocatalysis

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Postsynthetic Modifications of Iron-Carboxylate Nanoscale Metal−Organic Frameworks for Imaging and Drug Delivery

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Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents

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BioMOFs: Metal–Organic Frameworks for Biological and Medical Applications

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A Microporous Metal–Organic Framework for Gas‐Chromatographic Separation of Alkanes

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Antibody Targeting of Long-Circulating Lipidic Nanoparticles Does Not Increase Tumor Localization but Does Increase Internalization in Animal Models

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Cation-Triggered Drug Release from a Porous Zinc−Adeninate Metal−Organic Framework

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Rational Synthesis of Noncentrosymmetric Metal–Organic Frameworks for Second-Order Nonlinear Optics

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Metal–Organic Frameworks as A Tunable Platform for Designing Functional Molecular Materials

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Engineered Design of Mesoporous Silica Nanoparticles to Deliver Doxorubicin and P-Glycoprotein siRNA to Overcome Drug Resistance in a Cancer Cell Line

Meng, H., Liong, M., Xia, T., Li, Z., Ji, Z., Zink, J. I., & Nel, A. E. (2010) · ACS Nano · doi:10.1021/nn100690m · Cited by 900 · see citing works

Nanoscale Metal−Organic Frameworks as Potential Multimodal Contrast Enhancing Agents

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Nanoscale metal-organic frameworks for the co-delivery of cisplatin and pooled siRNAs to enhance therapeutic efficacy in drug-resistant ovarian cancer cells

He, C., Lu, K., Liu, D., & Lin, W. (2014) · Journal of the American Chemical Society · doi:10.1021/ja4098862 · Cited by 885 · see citing works

Metal–organic frameworks as potential drug carriers

Huxford, R. C., Rocca, J. D., & Lin, W. (2010) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2009.12.012 · Cited by 840 · see citing works

Progress of drug-loaded polymeric micelles into clinical studies

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Nanoscale Coordination Polymers for Platinum-Based Anticancer Drug Delivery

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Block copolymer micelles for drug delivery: Design, characterization and biological significance

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Porous Metal–Organic Frameworks for Heterogeneous Biomimetic Catalysis

Zhao, M., Sha, O., & Wu, C. (2014) · Accounts of Chemical Research · doi:10.1021/ar400265x · Cited by 725 · see citing works

The forthcoming applications of gold nanoparticles in drug and gene delivery systems

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Zeolite-like Metal−Organic Frameworks as Platforms for Applications: On Metalloporphyrin-Based Catalysts

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Spherical Nucleic Acid Nanoparticle Conjugates as an RNAi-Based Therapy for Glioblastoma

Jensen, S. A., Day, E. S., Ko, C. H., Hurley, L. A., Luciano, J. P., Kouri, F. M., Merkel, T. J., Luthi, A. J., Patel, P. C., Cutler, J. I., et al. (2013) · Science Translational Medicine · doi:10.1126/scitranslmed.3006839 · Cited by 592 · see citing works

Instantaneous and Quantitative Functionalization of Gold Nanoparticles with Thiolated DNA Using a pH-Assisted and Surfactant-Free Route

Zhang, X., Servos, M. R., & Liu, J. (2012) · Journal of the American Chemical Society · doi:10.1021/ja3014055 · Cited by 590 · see citing works

Codelivery of an Optimal Drug/siRNA Combination Using Mesoporous Silica Nanoparticles To Overcome Drug Resistance in Breast Cancer in Vitro and in Vivo

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Modular Synthesis of Functional Nanoscale Coordination Polymers

Lin, W., Rieter, W. J., & Taylor-Pashow, K. M. L. (2008) · Angewandte Chemie International Edition · doi:10.1002/anie.200803387 · Cited by 565 · see citing works

Chemical Synthesis and Assembly of Uniformly Sized Iron Oxide Nanoparticles for Medical Applications

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Monodisperse Magnetic Nanoparticles for Theranostic Applications

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Stress-Induced Chemical Detection Using Flexible Metal−Organic Frameworks

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Surfactant‐Assisted Synthesis of Nanoscale Gadolinium Metal–Organic Frameworks for Potential Multimodal Imaging

Taylor-Pashow, K. M. L., Jin, A., & Lin, W. (2008) · Angewandte Chemie International Edition · doi:10.1002/anie.200802911 · Cited by 415 · see citing works

Nanoparticle-based bio-barcode assay redefines “undetectable” PSA and biochemical recurrence after radical prostatectomy

Thaxton, C. S., Elghanian, R., Thomas, A. D., Stoeva, S. I., Lee, J., Smith, N. D., Schaeffer, A. J., Klocker, H., Horninger, W., Bartsch, G. C., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0904719106 · Cited by 387 · see citing works

Metal–Organic Frameworks as Sensory Materials and Imaging Agents

Liu, D., Lu, K., Poon, C. J., & Lin, W. (2013) · Inorganic Chemistry · doi:10.1021/ic402194c · Cited by 386 · see citing works

Energy Transfer Dynamics in Metal−Organic Frameworks

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Porphyrin–phospholipid liposomes permeabilized by near-infrared light

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Dendrimer‐Entrapped Gold Nanoparticles as a Platform for Cancer‐Cell Targeting and Imaging

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Lanthanide-doped upconverting luminescent nanoparticle platforms for optical imaging-guided drug delivery and therapy

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Biodegradable therapeutic MOFs for the delivery of bioactive molecules

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Hybrid nanomaterials for biomedical applications

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A New Class of Silica Cross-Linked Micellar Core−Shell Nanoparticles

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Self-Assembled Core–Shell Nanoparticles for Combined Chemotherapy and Photodynamic Therapy of Resistant Head and Neck Cancers

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Light Harvesting in Microscale Metal–Organic Frameworks by Energy Migration and Interfacial Electron Transfer Quenching

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Silica xerogel as an implantable carrier for controlled drug delivery—evaluation of drug distribution and tissue effects after implantation

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Self-assembled nanoscale coordination polymers with trigger release properties for effective anticancer therapy

Liu, D., Poon, C. J., Lu, K., He, C., & Lin, W. (2014) · Nature Communications · doi:10.1038/ncomms5182 · Cited by 251 · see citing works

Reusable oxidation catalysis using metal-monocatecholato species in a robust metal-organic framework.

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Iodinated Nanoscale Coordination Polymers as Potential Contrast Agents for Computed Tomography

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Iron Oxide-Based Nanostructures for MRI and Magnetic Hyperthermia

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Remote Triggered Release of Doxorubicin in Tumors by Synergistic Application of Thermosensitive Liposomes and Gold Nanorods

Agarwal, A., Mackey, M. A., El‐Sayed, M. A., & Bellamkonda, R. V. (2011) · ACS Nano · doi:10.1021/nn201010q · Cited by 232 · see citing works

Magnetically Triggered Dual Functional Nanoparticles for Resistance‐Free Apoptotic Hyperthermia

Yoo, D., Jeong, H., Noh, S., Lee, J., & Cheon, J. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201306557 · Cited by 231 · see citing works

Fabrication of Transferrin Functionalized Gold Nanoclusters/Graphene Oxide Nanocomposite for Turn-On Near-Infrared Fluorescent Bioimaging of Cancer Cells and Small Animals

Wang, Y., Chen, J., & Yan, X. (2013) · Analytical Chemistry · doi:10.1021/ac303747t · Cited by 207 · see citing works

Nanoscale Metal–Organic Frameworks: Magnetic Resonance Imaging Contrast Agents and Beyond

Rocca, J. D., & Lin, W. (2010) · European Journal of Inorganic Chemistry · doi:10.1002/ejic.201000496 · Cited by 202 · see citing works

Tandem catalysis with a bifunctional site-isolated Lewis acid–Brønsted base metal–organic framework, NH2-MIL-101(Al)

Srirambalaji, R., Hong, S., Natarajan, R., Yoon, M., Hota, R., Kim, Y., Ko, Y. H., & Kim, K. (2012) · Chemical Communications · doi:10.1039/c2cc36678a · Cited by 178 · see citing works

Lipid-coated nanoscale coordination polymers for targeted delivery of antifolates to cancer cells

Huxford, R. C., deKrafft, K. E., Boyle, W. S., Liu, D., & Lin, W. (2011) · Chemical Science · doi:10.1039/c1sc00499a · Cited by 177 · see citing works

Magnetic targeting of surface-modified superparamagnetic iron oxide nanoparticles yields antibacterial efficacy against biofilms of gentamicin-resistant staphylococci

Subbiahdoss, G., Sharifi, S., Grijpma, D. W., Laurent, S., van der Mei, H. C., Mahmoudi, M., & Busscher, H. J. (2012) · Acta Biomaterialia · doi:10.1016/j.actbio.2012.03.002 · Cited by 174 · see citing works

Multifunctional Enveloped Mesoporous Silica Nanoparticles for Subcellular Co-delivery of Drug and Therapeutic Peptide

Luo, G., Chen, W., Liu, Y., Lei, Q., Zhuo, R., & Zhang, X. (2014) · Scientific Reports · doi:10.1038/srep06064 · Cited by 167 · see citing works

Treatment of metastatic breast cancer by combination of chemotherapy and photothermal ablation using doxorubicin-loaded DNA wrapped gold nanorods

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Radiation Improves the Distribution and Uptake of Liposomal Doxorubicin (Caelyx) in Human Osteosarcoma Xenografts

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Targeting‐Triggered Porphysome Nanostructure Disruption for Activatable Photodynamic Therapy

Jin, C. S., Cui, L., Wang, F., Chen, J., & Zheng, G. (2014) · Advanced Healthcare Materials · doi:10.1002/adhm.201300651 · Cited by 153 · see citing works

Au-nanoparticle coated mesoporous silica nanocapsule-based multifunctional platform for ultrasound mediated imaging, cytoclasis and tumor ablation

Wang, X., Chen, H., Zheng, Y., Ma, M., Chen, Y., Zhang, K., Zeng, D., & Shi, J. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.11.044 · Cited by 148 · see citing works

Gold nanoparticle conjugates: recent advances toward clinical applications

Cao‐Milán, R., & Liz‐Marzán, L. M. (2014) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.2014.891582 · Cited by 143 · see citing works

Kinetics and Mechanism of Single-Stranded DNA Adsorption onto Citrate-Stabilized Gold Nanoparticles in Colloidal Solution

Nelson, E. M., & Rothberg, L. J. (2011) · Langmuir · doi:10.1021/la102613f · Cited by 137 · see citing works

Asymmetric Catalysis with Chiral Porous Metal–Organic Frameworks: Critical Issues

Wang, C., Zheng, M. J., & Lin, W. (2011) · The Journal of Physical Chemistry Letters · doi:10.1021/jz200492d · Cited by 133 · see citing works

Self-assembled nanoscale coordination polymers carrying oxaliplatin and gemcitabine for synergistic combination therapy of pancreatic cancer

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Self-assembled nanoscale coordination polymers carrying siRNAs and cisplatin for effective treatment of resistant ovarian cancer

He, C., Liu, D., & Lin, W. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.09.017 · Cited by 129 · see citing works

Effect of radiotherapy and hyperthermia on the tumor accumulation of HPMA copolymer-based drug delivery systems

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Enzymatic Regioselection for the Synthesis and Biodegradation of Porphysome Nanovesicles

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Exosome Encased Spherical Nucleic Acid Gold Nanoparticle Conjugates as Potent MicroRNA Regulation Agents

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Multifunctional hollow gold nanoparticles designed for triple combination therapy and CT imaging

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Clustered Magnetite Nanocrystals Cross-Linked with PEI for Efficient siRNA Delivery

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Postsynthetic diazeniumdiolate formation and NO release from MOFs

Nguyen, J. G., Tanabe, K. K., & Cohen, S. M. (2010) · CrystEngComm · doi:10.1039/c000154f · Cited by 100 · see citing works

Synthesis and functionalisation of magnetic nanoparticles for hyperthermia applications

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Multifunctional magnetic Fe3O4 nanoparticles combined with chemotherapy and hyperthermia to overcome multidrug resistance

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Polysilsesquioxane nanoparticles for triggered release of cisplatin and effective cancer chemoradiotherapy

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Hybrid Nano-carriers for Potential Drug Delivery

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Easy on-demand self-assembly of lateral nanodimensional hybrid graphene oxide flakes for near-infrared-induced chemothermal therapy

Thapa, R. K., Byeon, J. H., Ku, S., Yong, C. S., & Kim, J. O. (2017) · NPG Asia Materials · doi:10.1038/am.2017.141 · Cited by 27 · see citing works

Toxicity assessment of ZnO-decorated Au nanoparticles in the Mediterranean clam Ruditapes decussatus

Sellami, B., Mezni, A., Khazri, A., Bouzidi, I., Saidani, W., Sheehan, D., & Beyrem, H. (2017) · Aquatic Toxicology · doi:10.1016/j.aquatox.2017.04.005 · Cited by 26 · see citing works

The potential for clinical translation of antibody-targeted nanoparticles in the treatment of acute myeloid leukaemia

Guo, J., Luan, X., Cong, Z., Sun, Y., Wang, L., McKenna, S. L., Cahill, M. R., & O’Driscoll, C. M. (2018) · Journal of Controlled Release · doi:10.1016/j.jconrel.2018.07.024 · Cited by 26 · see citing works

DNA Nanotechnology for Multimodal Synergistic Theranostics

Yu, K., Qiao, Z., Song, W., & Bi, S. (2021) · Journal of Analysis and Testing · doi:10.1007/s41664-021-00182-z · Cited by 25 · see citing works

Recent Advances on Affibody- and DARPin-Conjugated Nanomaterials in Cancer Therapy

Gabriele, F., Palerma, M., Ippoliti, R., Angelucci, F., Pitari, G., & Ardini, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24108680 · Cited by 25 · see citing works

A method to selectively internalise submicrometer boron carbide particles into cancer cells using surface transferrin conjugation for developing a new boron neutron capture therapy agent

Tsuji, T., Yoshitomi, H., Ishikawa, Y., Koshizaki, N., Suzuki, M., & Usukura, J. (2019) · Journal of Experimental Nanoscience · doi:10.1080/17458080.2019.1692178 · Cited by 24 · see citing works

Combination photodynamic therapy of human breast cancer using salicylic acid and methylene blue

Hosseinzadeh, R., Khorsandi, K., & Jahanshiri, M. (2017) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2017.05.008 · Cited by 23 · see citing works

Polyunsaturated fatty acid-based targeted nanotherapeutics to enhance the therapeutic efficacy of docetaxel

Ramasamy, T., Sundaramoorthy, P., Ruttala, H., Choi, Y., Shin, W. H., Jeong, J.-H., Ku, S., Choi, H.-G., Kim, H.-M., Yong, C., et al. (2017) · Drug Delivery · doi:10.1080/10717544.2017.1373163 · Cited by 23 · see citing works

Fe3O4@Au core–shell hybrid nanocomposite for MRI-guided magnetic targeted photo-chemotherapy

Khani, T., Alamzadeh, Z., Sarikhani, A., Mousavi, M., Mirrahimi, M., Tabei, M., Irajirad, R., Abed, Z., & Beik, J. (2022) · Lasers in Medical Science · doi:10.1007/s10103-021-03486-9 · Cited by 25 · see citing works

Natural Salep/PEGylated Chitosan Double Layer toward a More Sustainable pH-Responsive Magnetite Nanocarrier for Targeted Delivery of DOX and Hyperthermia Application

Zohreh, N., Alipour, S., Hosseini, S. H., Xaba, M. S., Meijboom, R., Fasihi‐Ramandi, M., Gholipour, N., & Akhlaghi, M. (2019) · ACS Applied Nano Materials · doi:10.1021/acsanm.8b02076 · Cited by 22 · see citing works

Surface-modified nanotherapeutics targeting atherosclerosis

Li, W., Gonzalez, K. M., Chung, J., Kim, M., & Lu, J. (2022) · Biomaterials Science · doi:10.1039/d2bm00660j · Cited by 22 · see citing works

Brassica‐derived isothiocyanates as anticancer therapeutic agents and their nanodelivery

Rizwan, D., & Masoodi, F. A. (2023) · Phytotherapy Research · doi:10.1002/ptr.8042 · Cited by 22 · see citing works

Core-shell lipid polymer nanoparticles for combined chemo and gene therapy of childhood head and neck cancers

Zhang, T., Ma, J., Li, C., Lin, K. Y., Lou, F., Jiang, H., Gao, Y., Yang, Y., Ming, C., & Ruan, B. (2017) · Oncology Reports · doi:10.3892/or.2017.5365 · Cited by 22 · see citing works

Nanoparticles for tumor targeting

Jiang, T., Jin, K., Liu, X., & Pang, Z. (2017) · Elsevier eBooks · doi:10.1016/b978-0-08-101914-6.00008-9 · Cited by 22 · see citing works

Advances in Hybrid Vesicular-based Drug Delivery Systems: Improved Biocompatibility, Targeting, Therapeutic Efficacy and Pharmacokinetics of Anticancer Drugs

Setia, A., Sahu, R. K., Ray, S., Widyowati, R., Ekasari, W., & Saraf, S. (2022) · Current Drug Metabolism · doi:10.2174/1389200223666220627110049 · Cited by 21 · see citing works

Dually responsive gold–iron oxide heterodimers: merging stimuli-responsive surface properties with intrinsic inorganic material features

Kakwere, H., Materia, M. E., Curcio, A., Prato, M., Sathya, A., Nitti, S., & Pellegrino, T. (2018) · Nanoscale · doi:10.1039/c7nr06726g · Cited by 20 · see citing works

Surface‐functionalised hybrid nanoparticles for targeted treatment of cancer

Tariq, H., & Bokhari, S. A. I. (2020) · IET Nanobiotechnology · doi:10.1049/iet-nbt.2020.0073 · Cited by 18 · see citing works

Evaluation of the penetration process of fluorescent collagenase nanocapsules in a 3D collagen gel

Moreno, V., Baeza, A., & Vallet‐Regí, M. (2020) · Acta Biomaterialia · doi:10.1016/j.actbio.2020.12.022 · Cited by 18 · see citing works

Herbal based nanoparticles as a possible and potential treatment of cancer: a review

Yadav, R., Chawra, H. S., Dubey, G., Alam, M. S., Kumar, V., Sharma, P., Upadhyay, N. K., & Yadav, T. (2025) · Exploration of Targeted Anti-tumor Therapy · doi:10.37349/etat.2025.1002285 · Cited by 19 · see citing works

Carbon dots meet artificial intelligence: applications in biomedical engineering

Guo, Y., Liu, Y., Yang, J., Wu, Y., Lian, H., Tang, X., Li, C., Cui, W., & Guo, Z. (2025) · Journal of Materials Chemistry B · doi:10.1039/d5tb00593k · Cited by 17 · see citing works

Cancer and pulmonary hypertension: Learning lessons and real-life interplay

Pullamsetti, S. S., Nayakanti, S. R., Chelladurai, P., Mamazhakypov, A., Mansouri, S., Savai, R., & Seeger, W. (2020) · Global Cardiology Science and Practice · doi:10.21542/gcsp.2020.10 · Cited by 15 · see citing works

Nanoarchitectonics: Complexes and Conjugates of Platinum Drugs with Silicon Containing Nanocarriers. An Overview

Piórecka, K., Kurjata, J., & Stańczyk, W. A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22179264 · Cited by 15 · see citing works

Dual-Function Hybrid Nanoparticles with Gene Silencing and Anti-Inflammatory Effects

Fihurka, O., Sava, V., & Sanchez‐Ramos, J. (2022) · Nanomedicine · doi:10.2217/nnm-2021-0458 · Cited by 15 · see citing works

Photoacoustic contrast agents: a review focusing on image-guided therapy

Yang, X., Jiang, Z., Dai, J., Fu, Q., & Pan, S. (2025) · Nanoscale Horizons · doi:10.1039/d4nh00395k · Cited by 14 · see citing works

Multifunctional nanophotonic photoacoustic biosensors: a new era in molecular imaging–guided deep-tissue cancer monitoring

Taha, B. A., Sulaiman, G. M., Addie, A. J., Khalil, K., Ahmed, E. M., Chaudhary, V., & Arsad, N. (2025) · Methods · doi:10.1016/j.ymeth.2025.06.005 · Cited by 15 · see citing works

Structure-Based Evaluation of Hybrid Lipid–Polymer Nanoparticles: The Role of the Polymeric Guest

Chountoulesi, M., Pippa, Ν., Foryś, A., Trzebicka, B., & Pispas, S. (2024) · Polymers · doi:10.3390/polym16020290 · Cited by 14 · see citing works

Hybrid Nanoparticles as Drug Carriers for Controlled Chemotherapy of Cancer

Li, M., Luo, Z. Y., & Zhao, Y. (2016) · The Chemical Record · doi:10.1002/tcr.201600029 · Cited by 24 · see citing works

Design of Nanoparticles as Drug Carriers for Cancer Therapy.

Zhang, J., Lan, C. Q., Post, M. L., Simard, B., Deslandes, Y., & Hsieh, T. H. (2006) · PubMed · Cited by 70 · see citing works

Nanoparticles‐Mediated Combination Therapies for Cancer Treatment

Shrestha, B., Tang, L., & Romero, G. (2019) · Advanced Therapeutics · doi:10.1002/adtp.201900076 · Cited by 87 · see citing works

Lipid–polymer hybrid nanoparticles for synergistic drug delivery to overcome cancer drug resistance

Zeng, S.-Q., Chen, Y., Chen, Y., & Liu, H. (2017) · New Journal of Chemistry · doi:10.1039/c6nj02819e · Cited by 19 · see citing works

Targeted Hybrid Nanocarriers as Co-Delivery Systems for Enhanced Cancer Therapy

Erebor, J. O., Agboluaje, E. O., Perkins, A. M., Krishnakumar, M., & Ngwuluka, N. C. (2024) · Advanced Pharmaceutical Bulletin · doi:10.34172/apb.2024.046 · Cited by 22 · see citing works