Cited by 5,282Nanoparticle-Based Drug DeliveryAdvanced Drug Delivery SystemsRNA Interference and Gene Delivery

Recent advances with liposomes as pharmaceutical carriers

Torchilin, Vladimir P.·2005·Nature Reviews Drug Discovery

Abstract

Liposomes - microscopic phospholipid bubbles with a bilayered membrane structure - have received a lot of attention during the past 30 years as pharmaceutical carriers of great potential. More recently, many new developments have been seen in the area of liposomal drugs - from clinically approved products to new experimental applications, with gene delivery and cancer therapy still being the principal areas of interest. For further successful development of this field, promising trends must be identified and exploited, albeit with a clear understanding of the limitations of these approaches.

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Crossref · 10.1038/nrd1632

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Authors
Torchilin, V. P.
Affiliations
Northeastern University (US)
Corresponding author
Torchilin, Vladimir P.
Venue
Nature Reviews Drug Discovery
Published
2005-02
Volume
4
Issue
2
Pages
145-160
ISSN
  • 1474-1776 (ISSN-L)
  • 1474-1784
OpenAlex
W2061510929
Cited by
5,282
References
210
Citations by year
2026: 183 · 2025: 227 · 2024: 217 · 2023: 222 · 2022: 284 · 2021: 252 · 2020: 311 · 2019: 275 · 2018: 274 · 2017: 302 · 2016: 343 · 2015: 324 · 2014: 368 · 2013: 334 · 2012: 351
FWCI
7.98
Type
journal article
Language
en
Open access
closed
Locations
  • Nature Reviews Drug Discovery (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA Interference and Gene Delivery
Keywords
liposomes, drug carriers, liposomal drugs, gene delivery, cancer therapy, phospholipid bilayers, drug delivery systems
MeSH terms
Animals, Humans, Liposomes, Technology, Pharmaceutical

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