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The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.

Novel telomerase-increasing compound in mouse brain delays the onset of amyotrophic lateral sclerosis

Eitan, Erez, Tichon, Ailon, Gazit, Aviv, Gitler, Daniel, Slavin, Shimon, Priel, Esther·2012·EMBO Molecular Medicine
DOI 10.1002/emmm.201200212PMC PMC3376858
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Crossref · 10.1002/emmm.201200212

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  • Natural or synthetic compounds that induce TERT expression promote cellular survival and metabolic fitness.

    “Accordingly, natural or synthetic compounds that induce TERT expression have been shown to promote cellular survival and metabolic fitness.17–19”

    From TERT activation targets DNA methylation and multiple aging hallmarks (2024) · cites this paper as [18]

    The Results section reports that AGS-499 increased telomerase activity and improved survival of human cells exposed to oxidative stress; the benefit was absent when TERT was suppressed. The Discussion links TERT itself to improved respiratory-chain efficiency, but the paper does not show that AGS-499 improves metabolic fitness or establish the claim for natural compounds. (LLM, conf=0.86)

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Research works printed but not linked: 54

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Metadata

Authors
Eitan, E., Tichon, A., Gazit, A., Gitler, D., Slavin, S., & Priel, E.
Venue
EMBO Molecular Medicine
Publisher
Springer Science and Business Media LLC
Published
2012-02-20
Volume
4
Issue
4
Pages
313-329
ISSN
  • 1757-4676
  • 1757-4684
DOI
10.1002/emmm.201200212
PMC
PMC3376858
Cited by
82
References
12
Language
en
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