Toll‐like receptor 4 is required for α‐synuclein dependent activation of microglia and astroglia

Cited by (699)

Items 201–300 of 699

  1. Neuroinflammation in Synucleinopathies
    Somin Lim, Yewon Chun, Jun Sung Lee, Seung‐Jae Lee · 2016 · Brain Pathology
  2. NLRP3 Inflammasomes in Parkinson’s disease and their Regulation by Parkin
    Yiqun Yan, Yi Fang, Ran Zheng, Jiali Pu, Baorong Zhang · 2020 · Neuroscience
  3. Roles of α‑synuclein in gastrointestinal microbiome dysbiosis‑related Parkinson's disease progression (Review)
    Qingchun Lei, Tingting Wu, Jin Wu, Xiaogang Hu, Yingxia Guan, Ying Wang, Jinyuan Yan, Guolin Shi · 2021 · Molecular Medicine Reports
  4. Microglia in Parkinson’s Disease
    Nadia Stefanova · 2022 · Journal of Parkinson s Disease
  5. Microglia and Astrocytes Dysfunction and Key Neuroinflammation-Based Biomarkers in Parkinson’s Disease
    Kun Chen, Haoyang Wang, Iqra Ilyas, Arif Mahmood, Lijun Hou · 2023 · Brain Sciences
  6. Alpha-Synuclein Contribution to Neuronal and Glial Damage in Parkinson’s Disease
    Kamil Saramowicz, Natalia Siwecka, Grzegorz Galita, Aleksandra Kucharska-Lusina, Wioletta Rozpędek‐Kamińska, Ireneusz Majsterek · 2023 · International Journal of Molecular Sciences
  7. Multiple system atrophy: pathogenic mechanisms and biomarkers
    K. A. Jellinger, Gregor Karl Wenning · 2016 · Journal of Neural Transmission
  8. Innate immune responses to paraquat exposure in a Drosophila model of Parkinson’s disease
    Urmila Maitra, Michael Scaglione, Stanislava Chtarbanova, Janis M. O’Donnell · 2019 · Scientific Reports
  9. The Interplay between α-Synuclein and Microglia in α-Synucleinopathies
    Jacob Deyell, Manjari Sriparna, Mingyao Ying, Xiaobo Mao · 2023 · International Journal of Molecular Sciences
  10. Insights into the pathogenesis of multiple system atrophy: focus on glial cytoplasmic inclusions
    Seiji Kaji, Takakuni Maki, Tomoyuki Ishimoto, Hodaka Yamakado, Ryōsuke Takahashi · 2020 · Translational Neurodegeneration
  11. Progressive striatonigral degeneration in a transgenic mouse model of multiple system atrophy: translational implications for interventional therapies
    Refolo, Violetta, Bez, Francesco, Polissidis, Alexia, Kuzdas-Wood, Daniela, Sturm, Edith, Kamaratou, Martina, Poewe, Werner, Stefanis, Leonidas, Angela Cenci, M., Romero-Ramos, Marina et al. · 2018 · Acta Neuropathologica Communications
  12. Sex-specific cognitive deficits following space radiation exposure
    Parihar, Vipan K., Angulo, Maria C., Allen, Barrett D., Syage, Amber, Usmani, Manal T., Passerat de la Chapelle, Estrella, Amin, Amal Nayan, Flores, Lidia, Lin, Xiaomeng, Giedzinski, Erich et al. · 2020 · Frontiers in Behavioral Neuroscience
  13. Role of exosomes in the pathogenesis of inflammation in Parkinson’s disease
    Xinglong Yang, Kelu Li, Hongyan Huang, Hui Ren · 2022 · Neural Regeneration Research
  14. Glial cells involvement in spinal muscular atrophy: Could SMA be a neuroinflammatory disease?
    Elena Abati, Gaia Citterio, Nereo Bresolin, Giacomo P. Comi, Stefania Paola Corti · 2020 · Neurobiology of Disease
  15. Lenalidomide reduces microglial activation and behavioral deficits in a transgenic model of Parkinson’s disease
    Elvira Valera, Michael Mante, Scott Anderson, Edward M. Rockenstein, Eliezer Masliah · 2015 · Journal of Neuroinflammation
  16. Parkinson's disease: Microglial/macrophage-induced immunoexcitotoxicity as a central mechanism of neurodegeneration
    Russell L. Blaylock · 2017 · Surgical Neurology International
  17. Chemical modification of pro-inflammatory proteins by peroxynitrite increases activation of TLR4 and NF-κB: Implications for the health effects of air pollution and oxidative stress
    Kira Ziegler, Anna Theresa Kunert, Kathrin Reinmuth-Selzle, Anna Lena Leifke, Darius Widera, Michael G. Weller, Detlef Schuppan, Janine Fröhlich‐Nowoisky, Kurt Lucas, Ulrich Pöschl · 2020 · Redox Biology
  18. Microglia and astrocyte activation is region‐dependent in the α‐synuclein mouse model of Parkinson's disease
    Leyre Basurco, Miguel Angel Abellanas, Leyre Ayerra, Enrique Conde, Rodrigo Vinueza‐Gavilanes, Esther Luquin, África Vales, Amaya Vilas, Patxi San Martín‐Úriz, Ibón Tamayo et al. · 2022 · Glia
  19. Astroglial and microglial contributions to iron metabolism disturbance in Parkinson's disease
    Ning Song, Jun Wang, Hong Fu Jiang, Junxia Xie · 2018 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  20. Neuroinflammation in Parkinson’s Disease: Triggers, Mechanisms, and Immunotherapies
    Tai Wang, Changhe Shi, Haiyang Luo, Huimin Zheng, Liyuan Fan, Mibo Tang, Yun Su, Jing Yang, Chengyuan Mao, Yuming Xu · 2021 · The Neuroscientist
  21. Induction of microglial toll-like receptor 4 by prothrombin kringle-2: a potential pathogenic mechanism in Parkinson’s disease
    Won-Ho Shin, Min‐Tae Jeon, Eunju Leem, So-Yoon Won, Kyoung Hoon Jeong, Sang‐Joon Park, Catriona McLean, Sung Joong Lee, Byung Kwan Jin, Un Ju Jung et al. · 2015 · Scientific Reports
  22. Toll-Like Receptor 2 Signaling and Current Approaches for Therapeutic Modulation in Synucleinopathies
    Ian F. Caplan, Kathleen A. Maguire‐Zeiss · 2018 · Frontiers in Pharmacology
  23. Leucine-rich repeat kinase 2 (LRRK2) regulates α-synuclein clearance in microglia
    Maekawa, Tatsunori, Sasaoka, Toshikuni, Azuma, Sadahiro, Ichikawa, Takafumi, Melrose, Heather L., Farrer, Matthew J., Obata, Fumiya · 2016 · BMC Neuroscience
  24. Connexin 43 hemichannels and pannexin‐1 channels contribute to the α‐synuclein‐induced dysfunction and death of astrocytes
    Esteban F. Díaz, Valeria C. Labra, Tanhia F. Alvear, Luis A. Mellado, Carla A. Inostroza, Juan Esteban Oyarzún, Nicole Salgado, Rodrigo A. Quintanilla, Juan Andres Orellana · 2019 · Glia
  25. The multiple roles of exosomes in Parkinson's disease: an overview
    Chiara Porro, Maria Antonietta Panaro, Dario Domenico Lofrumento, Elona Hasalla, Teresa Trotta · 2019 · Immunopharmacology and Immunotoxicology
  26. Rifampicin and Its Derivative Rifampicin Quinone Reduce Microglial Inflammatory Responses and Neurodegeneration Induced In Vitro by α-Synuclein Fibrillary Aggregates
    Acuña, Leonardo, Hamadat, Sabah, Corbalán, Natalia S., González-Lizárraga, Florencia, dos-Santos-Pereira, Mauricio, Rocca, Jérémy, Sepúlveda Díaz, Julia, Del-Bel, Elaine, Papy-García, Dulce, Chehín, Rosana N. et al. · 2019 · Cells
  27. Multiple system atrophy: at the crossroads of cellular, molecular and genetic mechanisms
    Nadia Stefanova, Gregor Karl Wenning · 2023 · Nature reviews. Neuroscience
  28. Treatment of Complex Regional Pain Syndrome (CRPS) Using Low Dose Naltrexone (LDN)
    Pradeep Chopra, Mark Scott Cooper · 2013 · Journal of Neuroimmune Pharmacology
  29. Role of Microgliosis and NLRP3 Inflammasome in Parkinson’s Disease Pathogenesis and Therapy
    Fillipe Mendes de Araújo, Lorena Cuenca‐Bermejo, Emiliano Fernández‐Villalba, Sílvia Lima Costa, Víctor Diógenes Amaral da Silva, María Trinidad Herrero · 2021 · Cellular and Molecular Neurobiology
  30. Inflammation in dementia with Lewy bodies
    Jay Amin, Daniel Erskine, Paul C. Donaghy, Ajenthan Surendranathan, Peter Swann, Amy Kunicki, Delphine Boche, Clive Holmes, Ian Grant McKeith, John Tiernan O'Brien et al. · 2022 · Neurobiology of Disease
  31. The neuropathology of multiple system atrophy and its therapeutic implications
    Elvira Valera, Eliezer Masliah · 2017 · Autonomic Neuroscience
  32. Toll-like receptor-targeted anti-tumor therapies: Advances and challenges
    Yang Yang, Hongyi Li, Christina Fotopoulou, Paula Cunnea, Xia Zhao · 2022 · Frontiers in Immunology
  33. β1-integrin-dependent migration of microglia in response to neuron-released α-synuclein
    Changyoun Kim, Eun-Deok Cho, Hyung-Koo Kim, Sungyong You, He-Jin Lee, Daehee Hwang, Seung‐Jae Lee · 2014 · Experimental & Molecular Medicine
  34. Aldose Reductase Regulates Microglia/Macrophages Polarization Through the cAMP Response Element-Binding Protein After Spinal Cord Injury in Mice
    Qian Zhang, Ganlan Bian, Peng Chen, Ling Liu, Caiyong Yu, Fangfang Liu, Qian Xue, Sookja Kim Chung, Bing Song, Gong Ju et al. · 2014 · Molecular Neurobiology
  35. The degree of astrocyte activation in multiple system atrophy is inversely proportional to the distance to α-synuclein inclusions
    Rowan A. W. Radford, Alexandre Nay Rcom-H'cheo-Gauthier, Mathew B. Wong, Emma D. Eaton, M. Quilty, Catherine A. Blizzard, Anwar Norazit, Adrian Cuda Banda Meedeniya, James Clement Vickers, Wei Gai et al. · 2015 · Molecular and Cellular Neuroscience
  36. Mechanisms of Parkinson’s disease-related proteins in mediating secondary brain damage after cerebral ischemia
    TaeHee Kim, Raghu Vemuganti · 2017 · Journal of Cerebral Blood Flow & Metabolism
  37. LRRK2 and the Immune System
    Nicolas L. Dzamko · 2017 · Advances in neurobiology
  38. α-Synuclein and Glia in Parkinson’s Disease: A Beneficial or a Detrimental Duet for the Endo-Lysosomal System?
    Alice Filippini, Massimo Gennarelli, Isabella Russo · 2019 · Cellular and Molecular Neurobiology
  39. Dysregulation of mitochondrial and proteolysosomal genes in Parkinson’s disease myeloid cells
    Navarro, Elisa, Udine, Evan, Lopes, Katia de Paiva, Parks, Madison, Riboldi, Giulietta, Schilder, Brian M., Humphrey, Jack, Snijders, Gijsje J. L., Vialle, Ricardo A., Zhuang, Maojuan et al. · 2021 · Nature Aging
  40. Lithium Ameliorates LPS-Induced Astrocytes Activation Partly via Inhibition of Toll-Like Receptor 4 Expression
    Nana Li, Xiang Zhang, Hongquan Dong, Susu Zhang, Jie Sun, Yanning Qian · 2016 · Cellular Physiology and Biochemistry
  41. Dysregulation of the Gut-Brain Axis, Dysbiosis and Influence of Numerous Factors on Gut Microbiota Associated Parkinson's Disease
    Gagandeep Kaur, Tapan Behl, SIMONA GABRIELA BUNGAU, Arun Kumar, Md. Sahab Uddin, Vineet Mehta, Gökhan Zengin, Bijo Mathew, Muhammad Ajmal Shah, Sandeep Arora · 2020 · Current Neuropharmacology
  42. Intermediates of α-synuclein aggregation: Implications in Parkinson's disease pathogenesis
    Laxmikant G. Gadhe, Arunima Sakunthala, Semanti Mukherjee, Nitisha Gahlot, Riya Bera, Ajay Singh Sawner, Pradeep Kadu, Samir Kumar Maji · 2021 · Biophysical Chemistry
  43. Effect of probiotic supplementation on gastrointestinal motility, inflammation, motor, non-motor symptoms and mental health in Parkinson’s disease: a meta-analysis of randomized controlled trials
    Jong Mi Park, Sang Chul Lee, Chorom Ham, Yong Wook Kim · 2023 · Gut Pathogens
  44. Heat shock protein 70 suppresses neuroinflammation induced by α-synuclein in astrocytes
    Wenwen Yu, Sheng-Nan Cao, Caixia Zang, Lu Wang, Hanyu Yang, Xiu-Qi Bao, Dan Zhang · 2017 · Molecular and Cellular Neuroscience
  45. Diet, Microbiota and Brain Health: Unraveling the Network Intersecting Metabolism and Neurodegeneration
    Francesco Gentile, Pietro Emiliano Doneddu, Nilo Riva, Eduardo Nobile‐Orazio, Angelo Quattrini · 2020 · International Journal of Molecular Sciences
  46. Aberrant adenosine A2A receptor signaling contributes to neurodegeneration and cognitive impairments in a mouse model of synucleinopathy
    Qidi Hu, Xiangpeng Ren, Ya Liu, Zhihui Li, Liping Zhang, Xingjun Chen, Chaoxiang He, Jiang‐Fan Chen · 2016 · Experimental Neurology
  47. Review: Multiple system atrophy: emerging targets for interventional therapies
    Nadia Stefanova, Gregor Karl Wenning · 2016 · Neuropathology and Applied Neurobiology
  48. Inflammatory pre-conditioning restricts the seeded induction of α-synuclein pathology in wild type mice
    Emily J. Koller, Mieu Brooks, Todd Eliot Golde, Benoit I. Giasson, Paramita Chakrabarty · 2017 · Molecular Neurodegeneration
  49. Activated microglia facilitate the transmission of α-synuclein in Parkinson's disease
    Tingting Zheng, Zhengxiang Zhang · 2021 · Neurochemistry International
  50. Proteostasis of α-Synuclein and Its Role in the Pathogenesis of Parkinson’s Disease
    Deqiang Han, Wei Zheng, Xueyao Wang, Zhiguo Chen · 2020 · Frontiers in Cellular Neuroscience
  51. Innate immunity and cellular senescence: The good and the bad in the developmental and aged brain
    Santoro, Antonietta, Spinelli, Chiara Carmela, Martucciello, Stefania, Nori, Stefania Lucia, Capunzo, Mario, Puca, Annibale Alessandro, Ciaglia, Elena · 2018 · Journal of Leukocyte Biology
  52. Brain clearance of protein aggregates: a close-up on astrocytes
    Veronica Giusti, Gurkirat Kaur, Elena Giusto, Laura Civiero · 2024 · Molecular Neurodegeneration
  53. NOD2 promotes dopaminergic degeneration regulated by NADPH oxidase 2 in 6-hydroxydopamine model of Parkinson’s disease
    Li Ting Cheng, Lin Chen, Xinbing Wei, Yimeng Wang, Zhi-Ping Ren, Shenglan Zeng, Xiumei Zhang, Haitao Wen, Chengjiang Gao, Huiqing Liu · 2018 · Journal of Neuroinflammation
  54. The role of glia in protein aggregation
    Qingyun Li, Michael Seamus Haney · 2020 · Neurobiology of Disease
  55. Single-Cell Transcriptomics and In Situ Morphological Analyses Reveal Microglia Heterogeneity Across the Nigrostriatal Pathway
    Uriarte Huarte, Oihane, Kyriakis, Dimitrios, Heurtaux, Tony, Pires-Afonso, Yolanda, Grzyb, Kamil, Halder, Rashi, Buttini, Manuel, Skupin, Alexander, Mittelbronn, Michel, Michelucci, Alessandro · 2021 · Frontiers in Immunology
  56. Neurons and Glia Interplay in α-Synucleinopathies
    Panagiota Mavroeidi, Maria Xilouri · 2021 · International Journal of Molecular Sciences
  57. Association of Glial Activation and α-Synuclein Pathology in Parkinson’s Disease
    Rui Wang, Haigang Ren, Elena V. Kaznacheyeva, Xiaojun Lu, Guanghui Wang · 2022 · Neuroscience Bulletin
  58. Regulation of α-synuclein homeostasis and inflammasome activation by microglial autophagy
    Insup Choi, George R. Heaton, You-Kyung Lee, Zhenyu Yue · 2022 · Science Advances
  59. TLR-Mediated Signal Transduction and Neurodegenerative Disorders
    Adhikarla, Shashank Vishwanath, Jha, Niraj Kumar, Goswami, Vineet Kumar, Sharma, Ankur, Bhardwaj, Anuradha, Dey, Abhijit, Villa, Chiara, Kumar, Yatender, Jha, Saurabh Kumar · 2021 · Brain Sciences
  60. Regulation of microglia by glutamate and its signal pathway in neurodegenerative diseases
    Xinyue Zhang, Dan Wang, Bo Zhang, Jie Zhu, Zhulin Zhou, Li Cui · 2020 · Drug Discovery Today
  61. Transcriptional analysis of peripheral memory T cells reveals Parkinson’s disease-specific gene signatures
    Rekha Dhanwani, João Rodrigues Lima-Júnior, Ashu Sethi, John W. Pham, Gregory P. Williams, April Frazier, Yaqian Xu, Amy W. Amara, David G. Standaert, Jennifer G. Goldman et al. · 2022 · npj Parkinson s Disease
  62. Parkinson’s disease-derived α-synuclein assemblies combined with chronic-type inflammatory cues promote a neurotoxic microglial phenotype
    Cansu Yildirim-Balatan, Alexis Fenyi, Pierre Besnault, Lina Gomez, Julia Elisa Sepulveda-Diaz, Patrick Pierre Michel, Ronald Melki, Stéphane Hunot · 2024 · Journal of Neuroinflammation
  63. The Toll-Like Receptor Radical Cycle Pathway: A New Drug Target in Immune-Related Chronic Fatigue
    Kurt Lucas, Gerwyn Morris, George Anderson, Michael H. J. Maes · 2015 · CNS & Neurological Disorders - Drug Targets
  64. Asiatic acid attenuated apoptotic and inflammatory stress in the striatum of MPTP-treated mice
    Pei‐Chun Chao, Hsiang‐Lin Lee, Mei-Chin Yin · 2016 · Food & Function
  65. Nrf2/Wnt resilience orchestrates rejuvenation of glia-neuron dialogue in Parkinson's disease
    Bianca Marchetti · 2020 · Redox Biology
  66. Extracellular clusterin limits the uptake of α‐synuclein fibrils by murine and human astrocytes
    Alice Filippini, Veronica Mutti, Gaia Faustini, Francesca Longhena, Ileana Ramazzina, Federica Rizzi, Alice Kaganovich, Dorien A. Roosen, Natalie Landeck, Megan F. Duffy et al. · 2020 · Glia
  67. Mitochondrial Complex I as a Pathologic and Therapeutic Target for Parkinson’s Disease
    Kamatham Pushpa Tryphena, Sai Nikhil Uppala, Poojitha Pinjala, Saurabh Srivastava, Shashi Bala Singh, Dharmendra Kumar Khatri · 2023 · ACS Chemical Neuroscience
  68. Role of metabolic programming in the modulation of microglia phagocytosis by lipids
    Nadjar, A. · 2018 · Prostaglandins, Leukotrienes and Essential Fatty Acids
  69. Emerging targets of α-synuclein spreading in α-synucleinopathies: a review of mechanistic pathways and interventions
    Grace Kuo, Ramhari Kumbhar, William Blair, Valina Lynn Dawson, Ted M. Dawson, Xiaobo Mao · 2025 · Molecular Neurodegeneration
  70. Microglial dynamics and neuroinflammation in prodromal and early Parkinson’s disease
    Frida Lind‐Holm Mogensen, Philip Seibler, Anne Grünewald, Alessandro Michelucci · 2025 · Journal of Neuroinflammation
  71. Alpha-synuclein oligomer-selective antibodies reduce intracellular accumulation and mitochondrial impairment in alpha-synuclein exposed astrocytes
    Gabriel Gustafsson, Veronica Lindström, Jinar Rostami, Eva K. L. Nordström, Lars Lannfelt, Joakim J. E. Bergström, Martin Ingelsson, Anna Erlandsson · 2017 · Journal of Neuroinflammation
  72. Implications of the Human Gut–Brain and Gut–Cancer Axes for Future Nanomedicine
    Ibrahim Javed, Xuejing Cui, Xiaoyu Wang, Monika Mortimer, Nikolaos K. Andrikopoulos, Yuhuan Li, Thomas Paul Davis, Yuliang Zhao, Pu Chun Ke, Chunying Chen · 2020 · ACS Nano
  73. Impact of Microbiome–Brain Communication on Neuroinflammation and Neurodegeneration
    Iris Stolzer, Eveline Scherer, Patrick Süß, Veit Rothhammer, Beate Winner, Markus Friedrich Neurath, Claudia Günther · 2023 · International Journal of Molecular Sciences
  74. Genetic Defects and Pro-inflammatory Cytokines in Parkinson's Disease
    Magnusen, Albert Frank, Hatton, Shelby Loraine, Rani, Reena, Pandey, Manoj Kumar · 2021 · Frontiers in Neurology
  75. Extracellular Alpha-Synuclein: Mechanisms for Glial Cell Internalization and Activation
    Chavarría, Cecilia, Ivagnes, Rodrigo, Souza, José M. · 2022 · Biomolecules
  76. Inflammasomes: An Emerging Mechanism Translating Environmental Toxicant Exposure Into Neuroinflammation in Parkinson’s Disease
    Faith L. Anderson, Madeleine Coffey, Brent L. Berwin, Matthew C. Havrda · 2018 · Toxicological Sciences
  77. Prionoid Proteins in the Pathogenesis of Neurodegenerative Diseases
    Cameron Wells, Samuel E. Brennan, Matthew Keon, Nitin Saksena · 2019 · Frontiers in Molecular Neuroscience
  78. Spinal Cord Transection-Induced Allodynia in Rats – Behavioral, Physiopathological and Pharmacological Characterization
    Saïd M’Dahoma, Sylvie Bourgoin, Vale´rie Kayser, Sandrine Barthélémy, Caroline Chevarin, Farah Chali, D. Orsal, M. Hamon · 2014 · PLoS ONE
  79. Heat shock protein 60: an endogenous inducer of dopaminergic cell death in Parkinson disease
    Carmen Noelker, Lydie J. Morel, Anke Osterloh, Daniel Alvarez‐Fischer, Thomas Lescot, Minka Breloer, Maike Gold, Wolfgang Hermann Oertel, Carmen Henze, Patrick Pierre Michel et al. · 2014 · Journal of Neuroinflammation
  80. The Role of bFGF in the Excessive Activation of Astrocytes Is Related to the Inhibition of TLR4/NFκB Signals
    Libing Ye, Ying Yang, Xie Zhang, Pingtao Cai, Rui Li, Daqing Chen, Xiaojie Wei, Xuesong Zhang, Huazi Xu, Jian Xiao et al. · 2015 · International Journal of Molecular Sciences
  81. Altered Expression Patterns of Inflammation-Associated and Trophic Molecules in Substantia Nigra and Striatum Brain Samples from Parkinson's Disease, Incidental Lewy Body Disease and Normal Control Cases
    Douglas G. Walker, Lih‐Fen Lue, Geidy E. Serrano, Charles H. Adler, John N. Caviness, Lucia I. Sue, Thomas G. Beach · 2016 · Frontiers in Neuroscience
  82. Aquaporin 4: A key player in Parkinson's disease
    Omid Reza Tamtaji, Mohammad Behnam, Mohammad Ali Pourattar, Hamed Jafarpour, Zatollah Asemi · 2019 · Journal of Cellular Physiology
  83. Screening of Toll-Like Receptors Expression in Multiple System Atrophy Brains
    Brudek, Tomasz, Winge, Kristian, Agander, Tina Klitmøller, Pakkenberg, Bente · 2013 · Neurochemical Research
  84. MerTK is a mediator of alpha-synuclein fibril uptake by human microglia
    Marie‐France Dorion, Moein Yaqubi, Konstantin A. Senkevich, Nicholas W. Kieran, Adam MacDonald, Carol X.‐Q. Chen, Wen Luo, Amber Wallis, Irina Shlaifer, Jeffery Alan Hall et al. · 2023 · Brain
  85. Novel Immunotherapeutic Approaches to Target Alpha-Synuclein and Related Neuroinflammation in Parkinson’s Disease
    Maria Angela Samis Zella, Judith Metzdorf, Friederike Ostendorf, Fabian Maass, Siegfried Muhlack, Ralf Gold, Aiden Haghikia, Lars Tönges · 2019 · Cells
  86. Mitochondrial DAMPs: Key mediators in neuroinflammation and neurodegenerative disease pathogenesis
    Haihan Yu, Kaidi Ren, Yage Jin, Li Zhang, Hui Liu, Zhen Huang, Ziheng Zhang, Xing Chen, Yang Yang, Ziqing Wei · 2024 · Neuropharmacology
  87. Possible Link between SARS-CoV-2 Infection and Parkinson’s Disease: The Role of Toll-Like Receptor 4
    Carmela Conte · 2021 · International Journal of Molecular Sciences
  88. Microglial activation mediates host neuronal survival induced by neural stem cells
    Huimei Wu, Lifeng Zhang, Pei‐Shang Ding, Ya‐Jing Liu, Xu Wu, Jiang‐Ning Zhou · 2014 · Journal of Cellular and Molecular Medicine
  89. Porphyromonas gingivalis: a potential trigger of neurodegenerative disease
    Ziyan Huang, Miao Hao, Naixu Shi, Xinyu Wang, Yuan Lin, Haotian Yuan, Xiaofeng Wang · 2025 · Frontiers in Immunology
  90. Towards translational therapies for multiple system atrophy
    Daniela Kuzdas-Wood, Nadia Stefanova, K. A. Jellinger, Klaus Seppi, Michael G. Schlossmacher, Werner H Poewe, Gregor Karl Wenning · 2014 · Progress in Neurobiology
  91. Protein Partners of α‐Synuclein in Health and Disease
    Louise Berkhoudt Lassen, Lasse Reimer, Nelson Ferreira, Cristine Betzer, Poul Henning Jensen · 2016 · Brain Pathology
  92. Cerebral sterile inflammation in neurodegenerative diseases
    Otani, Kento, Shichita, Takashi · 2020 · Inflammation and Regeneration
  93. Do caffeine and more selective adenosine A2A receptor antagonists protect against dopaminergic neurodegeneration in Parkinson's disease?
    Chen, Jiang-Fan, Schwarzschild, Michael A. · 2020 · Parkinsonism & Related Disorders
  94. RETRACTED ARTICLE: Effects of innate immune receptor stimulation on extracellular α-synuclein uptake and degradation by brain resident cells
    Changyoun Kim, Somin Kwon, Michiyo Iba, Brian J. Spencer, Edward M. Rockenstein, Michael Mante, Anthony Adame, Soo Jean Shin, Jerel Adam Fields, Robert A. Rissman et al. · 2021 · Experimental & Molecular Medicine · Retracted
  95. Therapeutic Potential of Astrocyte Transplantation
    Nataly Hastings, Wei‐Li Kuan, Andrew Osborne, Mark Kotter · 2022 · Cell Transplantation
  96. Immune Regulatory Functions of Macrophages and Microglia in Central Nervous System Diseases
    Michael Poppell, Grace Hammel, Yi Ren · 2023 · International Journal of Molecular Sciences
  97. Helicobacter pylori infection and Parkinson’s Disease: etiology, pathogenesis and levodopa bioavailability
    Bang-rong Wei, Yujia Zhao, Yufeng Cheng, Chun Huang, Feng Zhang · 2024 · Immunity & Ageing
  98. Vinpocetine regulates levels of circulating TLRs in Parkinson’s disease patients
    Zhang Ping, Xiaomu Wu, Xie Xufang, Liang Shao · 2018 · Neurological Sciences
  99. Early TLR4 inhibition reduces hippocampal injury at puberty in a rat model of neonatal hypoxic-ischemic brain damage via regulation of neuroimmunity and synaptic plasticity
    Zhen Tang, Shaowu Cheng, Yanyan Sun, Yunqiao Zhang, Xiying Xiang, Zhicui Ouyang, Xing Zhu, Bo Wang, Mingyan Hei · 2019 · Experimental Neurology
  100. Targeting α-synuclein by PD03 AFFITOPE® and Anle138b rescues neurodegenerative pathology in a model of multiple system atrophy: clinical relevance
    Miguel Lemos, Serena Venezia, Violetta Refolo, Antonio Heras‐Garvin, Sabine M. Schmidhuber, Armin Giese, Andrei Leonov, Sergey Ryazanov, Christian Griesinger, Gergana Galabova et al. · 2020 · Translational Neurodegeneration