Cited by 102Dementia and Cognitive Impairment ResearchPhysical Activity and HealthDown syndrome and intellectual disability research

The effect of exercise on behavioural and psychological symptoms of dementia: the EVIDEM‐E randomised controlled clinical trial

Lowery, David, Cerga‐Pashoja, Arlinda, Iliffe, Steve, Thuné‐Boyle, Ingela, Griffin, Mark, Lee, James, Bailey, Alex, Bhattacharya, Rahul +1 more·2014·International Journal of Geriatric Psychiatry

Abstract

Objective: The objective of this study is to evaluate the effectiveness of a simple dyadic (person with dementia and their main carer) exercise regimen as a therapy for the behavioural and psychological symptoms of dementia. Method: A two arm, pragmatic, randomised, controlled, single‐blind, parallel‐group trial of a dyadic exercise regimen (individually tailored walking regimen designed to become progressively intensive and last between 20–30 min, at least five times per week).Community‐dwelling individuals with ICD‐10 confirmed dementia with the following: clinically significant behavioural and psychological symptoms, a carer willing and able to co‐participate in the exercise regimen, and no physical conditions or symptoms that would preclude exercise participation were invited by mental health or primary care services into the study. Results: One hundred and thirty‐one dyads were recruited to this study. There was no significant difference in Behavioural and Psychological Symptoms as measured by the Neuropsychiatric Inventory at week 12 between the group receiving the dyadic exercise regimen and those that did not (adjusted difference in means (intervention minus control) = −1.53, p = 0.6, 95% CI [−7.37, 4.32]). There was a significant between‐group difference in caregiver's burden as measured by the Zarit Caregiver Burden Inventory at week 12 (OR = 0.18, p = 0.01, CI [0.05, 0.69]) favouring the exercise group. Conclusions: This study found that regular simple exercise does not appear to improve the behavioural and psychological symptoms of dementia, but did seem to attenuate caregiver burden. Further study to improve exercise uptake are needed. Copyright © 2013 John Wiley & Sons, Ltd.

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Crossref · 10.1002/gps.4062

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Authors
Lowery, D., Cerga‐Pashoja, A., Iliffe, S., Thuné‐Boyle, I., Griffin, M., Lee, J., Bailey, A., Bhattacharya, R., & Warner, J.
Affiliations
  • Central and North West London NHS Foundation Trust (GB)
  • Central and North West London NHS Foundation Trust (CNWL) London UK
  • University College London (GB)
  • Independent exercise instructor Brighton UK
  • East London NHS Foundation Trust (GB)
Venue
International Journal of Geriatric Psychiatry
Publisher
Wiley
Published
2013-12-11
Volume
29
Issue
8
Pages
819-827
ISSN
  • 0885-6230 (ISSN-L)
  • 1099-1166
OpenAlex
W1953845853
Cited by
102
References
35
Citations by year
2026: 3 · 2025: 2 · 2024: 7 · 2023: 9 · 2022: 11 · 2021: 11 · 2020: 16 · 2019: 9 · 2018: 11 · 2017: 9 · 2016: 5 · 2015: 4 · 2014: 3 · 2013: 1
FWCI
3.07
Type
journal article
Language
en
Open access
closed
Locations
  • International Journal of Geriatric Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
  • UCL Discovery (University College London) (submittedVersion)
  • Kent Academic Repository (University of Kent) (submittedVersion)
  • LSHTM Research Online (London School of Hygiene and Tropical Medicine) (submittedVersion)
Funders
National Institute for Health Research (RP-PG-0606-1005)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Health Sciences › Medicine › Physiology › Physical Activity and Health
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Down syndrome and intellectual disability research
Keywords
dementia, behavioral and psychological symptoms of dementia, physical activity, walking, caregiver burden, caregivers, community-dwelling people with dementia, exercise therapy, exercise uptake
MeSH terms
Aged, Aged, 80 and over, Dementia, Exercise Therapy, Female, Humans, Male, Middle Aged, Psychiatric Status Rating Scales, Quality of Life, Stress, Psychological, Walking, Caregivers, Cost of Illness

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