The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
Altered functional connectivity in default mode network in absence epilepsy: A resting‐state fMRI study
Open accessAbstract
Dysfunctional default mode network (DMN) has been observed in various mental disorders, including epilepsy (see review Broyd et al. [2009]: Neurosci Biobehav Rev 33:279–296). Because interictal epileptic discharges may affect DMN, resting‐state fMRI was used in this study to determine DMN functional connectivity in 14 healthy controls and 12 absence epilepsy patients. To avoid interictal epileptic discharge effects, testing was performed within interictal durations when there were no interictal epileptic discharges. Cross‐correlation functional connectivity analysis with seed at posterior cingulate cortex, as well as region‐wise calculation in DMN, revealed decreased integration within DMN in the absence epilepsy patients. Region‐wise functional connectivity among the frontal, parietal, and temporal lobe was significantly decreased in the patient group. Moreover, functional connectivity between the frontal and parietal lobe revealed a significant negative correlation with epilepsy duration. These findings indicated DMN abnormalities in patients with absence epilepsy, even during resting interictal durations without interictal epileptic discharges. Abnormal functional connectivity in absence epilepsy may reflect abnormal anatomo‐functional architectural integration in DMN, as a result of cognitive mental impairment and unconsciousness during absence seizure. Hum Brain Mapp, 2011. © 2010 Wiley‐Liss, Inc.
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A default mode of brain function
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The Brain's Default Network: Anatomy, Function, and Relevance to Disease
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“Altered functional connectivity within the DMN is characteristic of altered network integrity, and is affiliated with mental disorder functions and aging in the resting state [Damoiseaux et al., 2008].”
BackgroundFunctional neuroimaging of autobiographical memory
Cabeza, R., & St Jacques, P. (2007) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2007.02.005 · Cited by 736
Cited by
Epileptic activity in Alzheimer’s disease: Causes and clinical relevance
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Chen, X., Lu, B., & Yan, C. (2018) · Human Brain Mapping · doi:10.1002/hbm.23843 · Cited by 340
Cao, W., Cao, X., Hou, C., Li, T., Cheng, Y., Jiang, L., Luo, C., Li, C., & Yao, D. (2016) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2016.00070 · Cited by 136
Self-citationDefault Network Connectivity in Medial Temporal Lobe Amnesia
Hayes, S. M., Salat, D. H., & Verfaellie, M. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.0700-12.2012 · Cited by 46
Chen, X., Duan, M., He, H., Yang, M., Klugah–Brown, B., Xu, H., Lai, Y., Luo, C., & Yao, D. (2016) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2016.09.006 · Cited by 38
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Metadata
- Authors
- Luo, C., Li, Q., Lai, Y., Xia, Y., Qin, Y., Liao, W., Li, S., Zhou, D., Yao, D., & Gong, Q.
- Venue
- Human Brain Mapping
- Publisher
- Wiley
- Published
- 2011-02-14
- Volume
- 32
- Issue
- 3
- Pages
- 438-449
- ISSN
- 1065-9471 (ISSN-L)
- 1097-0193
- OpenAlex
- W2044697872
- Cited by
- 257
- References
- 15
- FWCI
- 9.96
- Type
- journal article
- Language
- en
- Open access
- bronze
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