The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
Acceptance, availability, and feasibility of RTS, S/AS01 malaria vaccine: A review
Open accessAbstract
Introduction: In malaria‐stricken regions, malaria continues to be one of the primary causes of mortality for children. The number of malaria‐related fatalities has drastically decreased because of artemisinin‐based pharmacological regimens. Methods: Two independent researchers did a comprehensive literature search using PubMed/MEDLINE and Google Scholar from its inception to September 2022. Results: After evaluating RTS, S/AS01 for its safety, effectiveness, and feasibility, the European Medicines Agency (EMA) issued a favorable conclusion. It was suggested that the RTS, S malaria vaccine be used extensively by the World Health Organization on October 6, 2021. The successful pilot program testing the malaria vaccine in Ghana, Kenya, and Malawi served as the basis for this proposal. Conclusion: Several challenges need to be addressed to ensure the success of vaccination programs. From the acceptability perspective, issues such as inadequate community engagement, concerns about side effects, and issues with the delivery and quality of healthcare services can affect the acceptance of the vaccine. From the feasibility standpoint, factors such as lack of transportation or long distances to healthcare facilities and the perception of completion of the vaccination calendar can affect the feasibility of the vaccine. Lastly, the availability of the vaccine is also a major concern as it may not be readily available to meet the demands.
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In the citing paper
“Currently, RTS, S/AS01 (RTS, S) is the only malaria vaccine specifically recommended for use in pregnant women.”
From Current update on malaria in pregnancy: a systematic review (2025) · cites this paper as [218]
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In the citing paper
“There are no other vaccines available at this time for the prevention of malaria in pregnancy, apart from RTS, S, which is used in malaria-endemic regions, particularly during the second or third trimester of pregnancy [218, 219].”
From Current update on malaria in pregnancy: a systematic review (2025) · cites this paper as [218]
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Citations
Cites
Historical Origins of the Health Belief Model
Rosenstock, I. M. (1974) · Health Education Monographs · doi:10.1177/109019817400200403 · Cited by 6,116
Construct Validation of the Health Belief Model
Cummings, K. M., Jette, A. M., & Rosenstock, I. M. (1978) · Health Education Monographs · doi:10.1177/109019817800600406 · Cited by 975
RTS,S/AS01 vaccine (Mosquirix™): an overview
Laurens, M. B. (2020) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2019.1669415 · Cited by 491
Return On Investment From Childhood Immunization In Low- And Middle-Income Countries, 2011–20
Ozawa, S., Clark, S., Portnoy, A., Grewal, S., Brenzel, L., & Walker, D. G. (2016) · Health Affairs · doi:10.1377/hlthaff.2015.1086 · Cited by 371
Ethical Goals of Community Consultation in Research
Dickert, N., & Sugarman, J. (2005) · American Journal of Public Health · doi:10.2105/ajph.2004.058933 · Cited by 300
The Future of the RTS,S/AS01 Malaria Vaccine: An Alternative Development Plan
Gosling, R. D., & von Seidlein, L. (2016) · PLoS Medicine · doi:10.1371/journal.pmed.1001994 · Cited by 116
Assessing the Level and Determinants of COVID-19 Vaccine Confidence in Kenya
Orangi, S., Pinchoff, J., Mwanga, D. M., Abuya, T., Hamaluba, M., Warimwe, G. M., Austrian, K., & Barasa, E. (2021) · Vaccines · doi:10.3390/vaccines9080936 · Cited by 109
Mendoza, Y. G., Garric, E., Leach, A. J., Lievens, M., Ofori‐Anyinam, O., Pirçon, J., Stegmann, J., Vandoolaeghe, P., Otieno, L., Otieno, W., et al. (2019) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2019.1586040 · Cited by 103
RTS,S Malaria Vaccine and Increased Mortality in Girls
Klein, S. L., Shann, F. A., Moss, W. J., Benn, C. S., & Aaby, P. (2016) · mBio · doi:10.1128/mbio.00514-16 · Cited by 99
Cited by
Current update on malaria in pregnancy: a systematic review
Minwuyelet, A., Yewhalaw, D., Siferih, M., & Atenafu, G. (2025) · Tropical Diseases, Travel Medicine and Vaccines · doi:10.1186/s40794-025-00248-1 · Cited by 49
Metadata
- Authors
- Mumtaz, H., Nadeem, A., Bilal, W., Ansar, F., Saleem, S., Khan, Q. A., Tango, T., Farkouh, C., Belay, N. F., Verma, R., Farkouh, M., & Saqib, M.
- Affiliations
- Health Services Academy (PK)
- Dow University of Health Sciences (PK)
- King Abdullah Teaching Hospital Mansehra Pakistan
- Mayo Hospital (PK)
- DHQ and Teaching Hospital KDA Kohat Kohat Pakistan
- Faculty of Medicine Universitas Jakarta Indonesia
- Rush University Medical Center (US)
- Michigan State University (US)
- St. George's University (GD)
- Ponce Health Sciences University, St. Louis (US)
- Khyber Medical College (PK)
- Corresponding author
- Verma, Ravina
- ORCID
- Venue
- Immunity, Inflammation and Disease
- Publisher
- Wiley
- Published
- 2023-06
- Volume
- 11
- Issue
- 6
- Pages
- e899-e899
- ISSN
- 2050-4527 (ISSN-L)
- PMC
- PMC10266133
- OpenAlex
- W4380682435
- Cited by
- 42
- References
- 38
- Citations by year
- 2026: 5 · 2025: 17 · 2024: 16 · 2023: 4
- FWCI
- 2.07
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Immunity Inflammation and Disease (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Malaria Research and Control
- Social Sciences › Health › Vaccine Coverage and Hesitancy
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Travel-related health issues
- Keywords
- RTS,S/AS01 malaria vaccine, malaria vaccine, vaccine acceptance, vaccine availability, vaccine feasibility, vaccine safety and efficacy, community participation, vaccine side effects, health care access
- MeSH terms
- Child, Feasibility Studies, Ghana, Humans, Kenya, Malaria Vaccines, Drug-Related Side Effects and Adverse Reactions
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Cite CoChat for the checks on this page, and the paper for its own findings.
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- CoChat. (2026). Citation check: Acceptance, availability, and feasibility of RTS, S/AS01 malaria vaccine: A review. https://app.cochat.ai/papers/10.1002/iid3.899
- The paper
- Mumtaz, H., Nadeem, A., Bilal, W., Ansar, F., Saleem, S., Khan, Q. A., Tango, T., Farkouh, C., Belay, N. F., Verma, R., Farkouh, M., & Saqib, M. (2023). Acceptance, availability, and feasibility of RTS, S/AS01 malaria vaccine: A review. Immunity, Inflammation and Disease. https://doi.org/10.1002/iid3.899
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.