The international incidence of childhood cancer
Abstract
The International Agency for Research on Cancer has coordinated a worldwide study of the incidence of cancer in childhood. Contributors from over 50 countries have provided data. This paper presents a summary of some of the major results. The incidence rates and relative frequencies of childhood cancers are described according to I2 diagnostic groups, defined mainly in terms of tumour morphology. Variations in the risk of those tumours between different countries and different ethnic groups provide important information on the relative importance of environmental and genetic factors in their aetiology.
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Higher osteosarcoma incidence has been reported in South America and Africa than in Europe.
“However, a higher incidence has been reported in South America (7-7.6 per million young males in Colombia and Ecuador) and in Africa (Sudan and Uganda, relative frequency in childhood 5.3% and 6.4%, respectively) than in Europe (frequency ~2-3%) 10,11 .”
From Osteosarcoma (2022) · cites this paper as [11]
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- Authors
- Parkin, D. M., Stiller, C. A., Draper, G. J., & Bieber, C. A.
- Affiliations
- Centre international de recherche sur le cancer (FR)
- Corresponding author
- Parkin, D. M.
- ORCID
- Stiller, C. A.
- Venue
- International Journal of Cancer
- Publisher
- Wiley
- Published
- 1988-10-15
- Volume
- 42
- Issue
- 4
- Pages
- 511-520
- ISSN
- 0020-7136 (ISSN-L)
- 1097-0215
- OpenAlex
- W2006691249
- Cited by
- 1,022
- References
- 20
- Citations by year
- 2026: 6 · 2025: 10 · 2024: 16 · 2023: 21 · 2022: 33 · 2021: 18 · 2020: 30 · 2019: 27 · 2018: 22 · 2017: 28 · 2016: 36 · 2015: 33 · 2014: 38 · 2013: 42 · 2012: 34
- FWCI
- 9.28
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Cancer (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Oncology › Global Cancer Incidence and Screening
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Acute Lymphoblastic Leukemia research
- Health Sciences › Medicine › Oncology › Cancer Risks and Factors
- Keywords
- childhood cancer, cancer incidence, cross-national comparison, tumor morphology, diagnostic groups, ethnic differences, environmental risk factors, genetic risk factors, etiology
- MeSH terms
- Africa, Americas, Asia, Child, Europe, Humans, Neoplasms, Pacific Islands
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