Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods
Open accessAbstract
Estimates of the worldwide incidence and mortality from 36 cancers and for all cancers combined for the year 2018 are now available in the GLOBOCAN 2018 database, compiled and disseminated by the International Agency for Research on Cancer (IARC). This paper reviews the sources and methods used in compiling the cancer statistics in 185 countries. The validity of the national estimates depends upon the representativeness of the source information, and to take into account possible sources of bias, uncertainty intervals are now provided for the estimated sex‐ and site‐specific all‐ages number of new cancer cases and cancer deaths. We briefly describe the key results globally and by world region. There were an estimated 18.1 million (95% UI: 17.5–18.7 million) new cases of cancer (17 million excluding non‐melanoma skin cancer) and 9.6 million (95% UI: 9.3–9.8 million) deaths from cancer (9.5 million excluding non‐melanoma skin cancer) worldwide in 2018.
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Country-specific cervical cancer incidence data are based on GLOBOCAN estimates, which, where possible, are derived from extrapolation of recent trends in incidence obtained from national or subnational population-based cancer registries.
“Finally, our country-specific cervical cancer incidence data are based on GLOBOCAN estimates,42, 53 which, where possible, are derived from extrapolation of recent trends in incidence obtained from national or subnational population-based cancer registries.”
From Impact of HPV vaccination and cervical screening on cervical cancer elimination: a comparative modelling analysis in 78 low-income and lower-middle-income countries (2020) · cites this paper as [53]
The ‘Estimates of cancer incidence by country’ section says GLOBOCAN predicted 2018 rates from recent national incidence data for 45 countries. It also used subnational registry data, but describes using recent rates as proxies or modelling incidence from mortality—not extrapolating recent subnational incidence trends. The source therefore supports the general description but not that specific account of the subnational method. (LLM, conf=0.85)
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Bray, F., Ferlay, J., Soerjomataram, I., Siegel, R. L., Torre, L. A., & Jemal, A. (2018) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21492 · Cited by 84,109 · see citing works
Self-citationCancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012
Ferlay, J., Soerjomataram, I., Dikshit, R., Eser, S., Mathers, C., Rebelo, M., Parkin, D. M., Forman, D., & Bray, F. (2015) · International Journal of Cancer · doi:10.1002/ijc.29210 · Cited by 28,766 · see citing works
Self-citationEstimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
Ferlay, J., Shin, H.-R., Bray, F., Forman, D., Mathers, C., & Parkin, D. M. (2010) · International Journal of Cancer · doi:10.1002/ijc.25516 · Cited by 22,207 · see citing works
Self-citationVos, T., Abajobir, A. A., Abate, K. H., Abbafati, C., Abbas, K. M., Abd-Allah, F., Abdulkader, R. S., Abdulle, A. M., Abebo, T. A., Abera, S. F., et al. (2017) · The Lancet · doi:10.1016/s0140-6736(17)32154-2 · Cited by 13,220 · see citing works
Cancer Incidence in Five Continents
(1966) · doi:10.1007/978-3-642-85849-9 · Cited by 5,936 · see citing works
Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012
Ferlay, J., Steliarova‐Foucher, E., Lortet‐Tieulent, J., Rosso, S., Coebergh, J. W. W., Comber, H., Forman, D., & Bray, F. (2013) · European Journal of Cancer · doi:10.1016/j.ejca.2012.12.027 · Cited by 5,243 · see citing works
Self-citationGlobal burden of cancers attributable to infections in 2012: a synthetic analysis
Plummer, M., de Martel, C., Vignat, J., Ferlay, J., Bray, F., & Franceschi, S. (2016) · The Lancet Global Health · doi:10.1016/s2214-109x(16)30143-7 · Cited by 1,634 · see citing works
Self-citationUnited Nations Population Division
Wheldon, M. C., Raftery, A. E., Clark, S. J., & Gerland, P. (2009) · Springer eBooks · doi:10.1007/978-0-387-78665-0_6852 · Cited by 982 · see citing works
Cancer mortality for selected sites in 24 countries
栗原, 登., & 瀬木, 三. (1960) · Medical Entomology and Zoology · Cited by 880 · see citing works
Guidelines for accurate and transparent health estimates reporting: the GATHER statement
Stevens, G. A., Alkema, L., Black, R. E., Boerma, J. T., Collins, G. S., Ezzati, M., Grove, J. T., Hogan, D. R., Hogan, M. C., Horton, R., et al. (2016) · PLOS Medicine · doi:10.1371/journal.pmed.1002056 · Cited by 424 · see citing works
Self-citationIncidence and prevalence of non‐melanoma skin cancer in A ustralia: A systematic review
Perera, E., Gnaneswaran, N., Staines, C., Win, A. K., & Sinclair, R. D. (2015) · Australasian Journal of Dermatology · doi:10.1111/ajd.12282 · Cited by 210 · see citing works
Estimation of the global burden of mesothelioma deaths from incomplete national mortality data
Chimed‐Ochir, O., Takahashi, K., Sorahan, T., Driscoll, T., Fitzmaurice, C., Yoko-o, M., Sawanyawisuth, K., Furuya, S., Tanaka, F., Horie, S., et al. (2017) · Occupational and Environmental Medicine · doi:10.1136/oemed-2017-104298 · Cited by 160 · see citing works
An assessment of GLOBOCAN methods for deriving national estimates of cancer incidence
Antoni, S., Soerjomataram, I., Møller, B., Bray, F., & Ferlay, J. (2016) · Bulletin of the World Health Organization · doi:10.2471/blt.15.164384 · Cited by 115 · see citing works
Self-citationPiñeros, M., Znaor, A., Mery, L., & Bray, F. (2017) · Epidemiologic Reviews · doi:10.1093/epirev/mxx003 · Cited by 111 · see citing works
Self-citation(2017) · The SHAFR Guide Online · doi:10.1163/2468-1733_shafr_sim010030021 · Cited by 77 · see citing works
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- Dyba T, Hakulinen T. Comparison of different approaches to incidence prediction based on sim- ple interpolation techniques. Stat Med 2000;19: 1741-52. 1952 GLOBOCAN 2018 sources and methods Int. J. Cancer: 144, 1941-1953 (2019) © 2018 UICC Cancer Epidemiology 10970215, 2019, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/ijc.31937 by Readcube (Labtiva Inc.), Wiley Online Library on [14/08/2023]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License · DOI
Cited by
Sorted by citations
Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A., & Bray, F. (2021) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21660 · Cited by 108,699 · see citing works
Self-citationBray, F., Laversanne, M., Sung, H., Ferlay, J., Siegel, R. L., Soerjomataram, I., & Jemal, A. (2024) · CA: a cancer journal for clinicians · doi:10.3322/caac.21834 · Cited by 27,064 · see citing works
Self-citationCancer statistics for the year 2020: An overview
Ferlay, J., Colombet, M., Soerjomataram, I., Parkin, D. M., Piñeros, M., Znaor, A., & Bray, F. (2021) · International Journal of Cancer · doi:10.1002/ijc.33588 · Cited by 5,963 · see citing works
Self-citationHead and neck squamous cell carcinoma
Johnson, D. E., Burtness, B. A., Leemans, C. R., Lui, V. W. Y., Bauman, J. E., & Grandis, J. R. (2020) · Nature Reviews Disease Primers · doi:10.1038/s41572-020-00224-3 · Cited by 4,292 · see citing works
Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis
Arbyn, M., Weiderpass, E., Bruni, L., de Sanjosé, S., Saraiya, M., Ferlay, J., & Bray, F. (2019) · The Lancet Global Health · doi:10.1016/s2214-109x(19)30482-6 · Cited by 4,241 · see citing works
Self-citationCurrent and future burden of breast cancer: Global statistics for 2020 and 2040
Arnold, M., Morgan, E., Rumgay, H., Mafra, A., Singh, D., Laversanne, M., Vignat, J., Gralow, J. R., Cardoso, F., Siesling, S., et al. (2022) · The Breast · doi:10.1016/j.breast.2022.08.010 · Cited by 3,411 · see citing works
Self-citationGlobal burden of colorectal cancer in 2020 and 2040: incidence and mortality estimates from GLOBOCAN
Morgan, E., Arnold, M., Gini, A., Lorenzoni, V, Cabasag, C. J., Laversanne, M., Vignat, J., Ferlay, J., Murphy, N., & Bray, F. (2023) · Gut · doi:10.1136/gutjnl-2022-327736 · Cited by 2,429 · see citing works
Self-citationGlobal burden of cancer attributable to infections in 2018: a worldwide incidence analysis
de Martel, C., Georges, D., Bray, F., Ferlay, J., & Clifford, G. M. (2020) · The Lancet Global Health · doi:10.1016/s2214-109x(19)30488-7 · Cited by 2,475 · see citing works
Self-citationCancer incidence and mortality in China, 2016
Zheng, R., Sun, K., Han, B., Li, L., Chen, R., Wang, S., Li, L., Zeng, H., He, J., Wei, W., et al. (2022) · Journal of the National Cancer Center · doi:10.1016/j.jncc.2022.02.002 · Cited by 1,515 · see citing works
Global Burden of Cutaneous Melanoma in 2020 and Projections to 2040
Arnold, M., Singh, D., Laversanne, M., Vignat, J., Vaccarella, S., Meheus, F., Cust, A. E., de Vries, E., Whiteman, D. C., & Bray, F. (2022) · JAMA Dermatology · doi:10.1001/jamadermatol.2022.0160 · Cited by 1,535 · see citing works
Self-citationAdvances in immunotherapy for hepatocellular carcinoma
Sangro, B., Sarobe, P., Hervás-Stubbs, S., & Melero, I. (2021) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-021-00438-0 · Cited by 1,306 · see citing works
Pancreatic cancer epidemiology: understanding the role of lifestyle and inherited risk factors
Klein, A. P. (2021) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-021-00457-x · Cited by 1,258 · see citing works
Morgan, E., Soerjomataram, I., Rumgay, H., Coleman, H. G., Thrift, A. P., Vignat, J., Laversanne, M., Ferlay, J., & Arnold, M. (2022) · Gastroenterology · doi:10.1053/j.gastro.2022.05.054 · Cited by 1,242 · see citing works
Self-citationRebello, R. J., Oing, C., Knudsen, K. E., Loeb, S., Johnson, D. C., Reiter, R. E., Gillessen, S., van der Kwast, T., & Bristow, R. G. (2021) · Nature Reviews Disease Primers · doi:10.1038/s41572-020-00243-0 · Cited by 1,157 · see citing works
The global burden of urinary bladder cancer: an update
Richters, A., Aben, K. K. H., & Kiemeney, L. A. L. M. (2019) · World Journal of Urology · doi:10.1007/s00345-019-02984-4 · Cited by 972 · see citing works
Brisson, M., Kim, J. J., Canfell, K., Drolet, M., Gingras, G., Burger, E. A., Martin, D., Simms, K. T., Bénard, É., Boily, M.-C., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30068-4 · Cited by 943 · see citing works
Self-citationMiranda‐Filho, A., Laversanne, M., Ferlay, J., Colombet, M., Piñeros, M., Znaor, A., Parkin, D. M., Soerjomataram, I., & Bray, F. (2024) · International Journal of Cancer · doi:10.1002/ijc.35278 · Cited by 993 · see citing works
Self-citationCancer incidence estimates for 2022 & projection for 2025
Sathishkumar, K., Chaturvedi, M., Das, P., Stephen, S., & Mathur, P. (2022) · The Indian Journal of Medical Research · doi:10.4103/ijmr.ijmr_1821_22 · Cited by 866 · see citing works
Morgan, E., Arnold, M., Camargo, M. C., Gini, A., Kunzmann, A. T., Matsuda, T., Meheus, F., Verhoeven, R. H. A., Vignat, J., Laversanne, M., et al. (2022) · EClinicalMedicine · doi:10.1016/j.eclinm.2022.101404 · Cited by 806 · see citing works
Self-citationGenetic and molecular epidemiology of adult diffuse glioma
Molinaro, A. M., Taylor, J. W., Wiencke, J. K., & Wrensch, M. (2019) · Nature Reviews Neurology · doi:10.1038/s41582-019-0220-2 · Cited by 708 · see citing works
The anti-cancer effect of quercetin: molecular implications in cancer metabolism
Reyes-Farias, M., & Carrasco-Pozo, C. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20133177 · Cited by 689 · see citing works
“6 million deaths caused by cancer disease [1].”
BackgroundPizzato, M., Li, M., Vignat, J., Laversanne, M., Singh, D., Vecchia, C. L., & Vaccarella, S. (2022) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(22)00035-3 · Cited by 724 · see citing works
Makker, V., MacKay, H. J., Ray-Coquard, I. L., Levine, D. A., Westin, S. N., Aoki, D., & Oaknin, A. (2021) · Nature Reviews Disease Primers · doi:10.1038/s41572-021-00324-8 · Cited by 705 · see citing works
Endometrial cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up
Oaknin, A., Bosse, T., Creutzberg, C. L., Giornelli, G. H., Harter, P., Joly, F., Lorusso, D., Marth, C., Makker, V., Mirza, M. R., et al. (2022) · Annals of Oncology · doi:10.1016/j.annonc.2022.05.009 · Cited by 680 · see citing works
Dyba, T. A., Randi, G., Bray, F., Martos, C., Giusti, F., Nicholson, N. C., Gavin, A., Flego, M., Neamţiu, L., Dimitrova, N., et al. (2021) · European Journal of Cancer · doi:10.1016/j.ejca.2021.07.039 · Cited by 645 · see citing works
Self-citationCA125 and Ovarian Cancer: A Comprehensive Review
Charkhchi, P., Cybulski, C., Gronwald, J., Wong, F. O., Narod, S. A., & Akbari, M. R. (2020) · Cancers · doi:10.3390/cancers12123730 · Cited by 607 · see citing works
Global burden of oesophageal and gastric cancer by histology and subsite in 2018
Arnold, M., Ferlay, J., Henegouwen, M. I. V. B., & Soerjomataram, I. (2020) · Gut · doi:10.1136/gutjnl-2020-321600 · Cited by 607 · see citing works
Self-citationAnjum, S., Hashim, M., Malik, S. A., Khan, M., Lorenzo, J. M., Abbasi, B. H., & Hano, C. (2021) · Cancers · doi:10.3390/cancers13184570 · Cited by 597 · see citing works
Paclitaxel’s Mechanistic and Clinical Effects on Breast Cancer
Samaan, T. M. A., Samec, M., Líšková, A., Kubatka, P., & Büsselberg, D. (2019) · Biomolecules · doi:10.3390/biom9120789 · Cited by 580 · see citing works
Cervical cancer in low and middle‑income countries (Review)
Hull, R., Mbele, M., Makhafola, T. J., Hicks, C., Wang, S., Reis, R. M., Mehrotra, R., Mkhize‐Kwitshana, Z. L., Kibiki, G. S., Bates, D. O., et al. (2020) · Oncology Letters · doi:10.3892/ol.2020.11754 · Cited by 570 · see citing works
Worldwide Burden of, Risk Factors for, and Trends in Pancreatic Cancer
Huang, J., Lok, V., Ngai, C. H., Zhang, L., Yuan, J., Lao, X. Q., Ng, K. K., Chong, C. C. N., Zheng, Z., & Wong, M. C. S. (2020) · Gastroenterology · doi:10.1053/j.gastro.2020.10.007 · Cited by 539 · see citing works
Lipid-Based Nanoparticles: Application and Recent Advances in Cancer Treatment
García-Pinel, B., Porras-Alcalá, C., Ortega-Rodríguez, A., Sarabia, F., Prados, J. C., Melguizo, C., & López‐Romero, J. M. (2019) · Nanomaterials · doi:10.3390/nano9040638 · Cited by 530 · see citing works
Chen, S., Zhu, G., Yang, Y., Wang, F., Xiao, Y., Zhang, N., Bian, X., Zhu, Y., Yu, Y., Liu, F., et al. (2021) · Nature Cell Biology · doi:10.1038/s41556-020-00613-6 · Cited by 504 · see citing works
Epidemiology of stomach cancer
Ilić, M., & Ilić, I. (2022) · World Journal of Gastroenterology · doi:10.3748/wjg.v28.i12.1187 · Cited by 513 · see citing works
Detection and characterization of lung cancer using cell-free DNA fragmentomes
Mathios, D., Johansen, J. S., Cristiano, S., Medina, J. E., Phallen, J. A., Larsen, K. R., Bruhm, D. C., Niknafs, N., Ferreira, L., Adleff, V., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-24994-w · Cited by 476 · see citing works
Applications and Limitations of Dendrimers in Biomedicine
Chiş, A. A., Dobrea, C. M., Morgovan, C., Arseniu, A. M., Rus, L. L., Butucă, A., Juncan, A. M., Totan, M., Vonica-Țincu, A. L., Cormoș, G., et al. (2020) · Molecules · doi:10.3390/molecules25173982 · Cited by 469 · see citing works
Recent Advances in Hyperthermia Therapy‐Based Synergistic Immunotherapy
Chang, M., Hou, Z., Wang, M., Li, C., & Lin, J. (2020) · Advanced Materials · doi:10.1002/adma.202004788 · Cited by 452 · see citing works
Recent advances in selective photothermal therapy of tumor
Zhao, L., Zhang, X., Wang, X., Guan, X., Zhang, W., & Ma, J. (2021) · Journal of Nanobiotechnology · doi:10.1186/s12951-021-01080-3 · Cited by 446 · see citing works
Global patterns and trends in cancers of the lip, tongue and mouth
Miranda‐Filho, A., & Bray, F. (2020) · Oral Oncology · doi:10.1016/j.oraloncology.2019.104551 · Cited by 458 · see citing works
Self-citationEstimativa de Incidência de Câncer no Brasil, 2023-2025
Santos, M. D. O., de Lima, F. C. D. S., Martins, L. F. L., Oliveira, J. F. P., de Almeida, L. M., & Cancela, M. D. C. (2023) · Revista Brasileira de Cancerologia · doi:10.32635/2176-9745.rbc.2023v69n1.3700 · Cited by 643 · see citing works
Priorities for cancer research in low- and middle-income countries: a global perspective
Pramesh, C. S., Badwe, R. A., Bhoo‐Pathy, N., Booth, C. M., Chinnaswamy, G., Dare, A. J., de Andrade, V. P., Hunter, D. J., Gopal, S., Gospodarowicz, M. K., et al. (2022) · Nature Medicine · doi:10.1038/s41591-022-01738-x · Cited by 438 · see citing works
Estimating the total incidence of global childhood cancer: a simulation-based analysis
Ward, Z. J., Yeh, J. M., Bhakta, N. H., Frazier, A. L., & Atun, R. A. (2019) · The Lancet Oncology · doi:10.1016/s1470-2045(18)30909-4 · Cited by 438 · see citing works
Moore, K. N., Bookman, M. A., Sehouli, J., Miller, A., Anderson, C. K., Scambia, G., Myers, T. K. N., Taşkıran, Ç., Robison, K. M., Maenpaa, J. U., et al. (2021) · Journal of Clinical Oncology · doi:10.1200/jco.21.00306 · Cited by 418 · see citing works
Cancer in sub-Saharan Africa: a Lancet Oncology Commission
Ngwa, W. F., Addai, B. W., Adewole, I. F., Ainsworth, V., Alaro, J., Alatise, O. I., Ali, Z. V., Anderson, B. O., Anorlu, R. I., Avery, S., et al. (2022) · The Lancet Oncology · doi:10.1016/s1470-2045(21)00720-8 · Cited by 441 · see citing works
Force, L. M., Abdollahpour, I., Advani, S. M., Agius, D., Ahmadian, E., Alahdab, F., Alam, S., Alebel, A., Alipour, V., Allen, C. A., et al. (2019) · The Lancet Oncology · doi:10.1016/s1470-2045(19)30339-0 · Cited by 403 · see citing works
Molecular Mechanisms of Colon Cancer Progression and Metastasis: Recent Insights and Advancements
Malki, A. M., Abu-El-Ruz, R., Gupta, I., Allouch, A., Vranić, S., & Moustafa, A. A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms22010130 · Cited by 409 · see citing works
An Overview of PARP Inhibitors for the Treatment of Breast Cancer
Cortesi, L., Rugo, H. S., & Jackisch, C. (2021) · Targeted Oncology · doi:10.1007/s11523-021-00796-4 · Cited by 396 · see citing works
Anticancer activities of TCM and their active components against tumor metastasis
Wang, K., Chen, Q., Shao, Y., Yin, S., Liu, C., Liu, Y., Wang, R., Wang, T., Qiu, Y., & Yu, H. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.111044 · Cited by 385 · see citing works
van Hoogstraten, L. M. C., Vrieling, A., van der Heijden, A. G., Kogevinas, M., Richters, A., & Kiemeney, L. A. L. M. (2023) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-023-00744-3 · Cited by 392 · see citing works
The multidisciplinary management of rectal cancer
Keller, D. S., Berho, M. E., Perez, R. O., Wexner, S. D., & Chand, M. (2020) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-020-0275-y · Cited by 369 · see citing works
Estimated global cancer incidence in the oldest adults in 2018 and projections to 2050
Pilleron, S., Soto‐Pérez‐de‐Celis, E., Vignat, J., Ferlay, J., Soerjomataram, I., Bray, F., & Sarfati, D. (2020) · International Journal of Cancer · doi:10.1002/ijc.33232 · Cited by 359 · see citing works
Self-citationAn updated systematic review and meta-analysis on adherence to mediterranean diet and risk of cancer
Morze, J., Danielewicz, A., Przybyłowicz, K. E., Zeng, H., HOFFMANN, G. E., & Schwingshackl, L. (2020) · European Journal of Nutrition · doi:10.1007/s00394-020-02346-6 · Cited by 363 · see citing works
Ebeling, P. R., Nguyen, H. H., Aleksova, J., Vincent, A. J., Wong, P., & Milat, F. (2021) · Endocrine Reviews · doi:10.1210/endrev/bnab028 · Cited by 354 · see citing works
Signaling pathways and therapeutic interventions in gastric cancer
Lei, Z., Teng, Q., Qin, T. L., Chen, W., Xie, Y., Wu, K., Zeng, Q., Zeng, L., Pan, Y., Chen, Z., et al. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-01190-w · Cited by 325 · see citing works
Rahaman, M. M., Li, C., Yao, Y., Kulwa, F., Wu, X., Li, X., & Wang, Q. (2021) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2021.104649 · Cited by 334 · see citing works
An overview of spirooxindole as a promising scaffold for novel drug discovery
Zhou, L., Qu, R., & Yang, G. (2020) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2020.1733526 · Cited by 323 · see citing works
Curcumin and colorectal cancer: An update and current perspective on this natural medicine
Weng, W., & Goel, A. (2020) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2020.02.011 · Cited by 318 · see citing works
Digital health for optimal supportive care in oncology: benefits, limits, and future perspectives
Aapro, M., Bossi, P., Dasari, A. N., Fallowfield, L. J., Gascón, P., Geller, M. A., Jordan, K., Kim, J. W., Martin, K., & Porzig, S. (2020) · Supportive Care in Cancer · doi:10.1007/s00520-020-05539-1 · Cited by 318 · see citing works
Lipid alterations in chronic liver disease and liver cancer
Paul, B., Lewińska, M., & Andersen, J. B. (2022) · JHEP Reports · doi:10.1016/j.jhepr.2022.100479 · Cited by 311 · see citing works
Improving head and neck cancer therapies by immunomodulation of the tumour microenvironment
Ruffin, A., Li, H., Vujanović, L., Zandberg, D., Ferris, R., & Bruno, T. (2022) · Nature Reviews. Cancer · doi:10.1038/s41568-022-00531-9 · Cited by 293 · see citing works
Cancer Stem Cells and Radioresistance: DNA Repair and Beyond
Schulz, A., Meyer, F. B., Dubrovska, A., & Borgmann, K. (2019) · Cancers · doi:10.3390/cancers11060862 · Cited by 306 · see citing works
Huang, S., Yang, J., Shen, N., Xu, Q., & Zhao, Q. (2023) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2023.01.006 · Cited by 275 · see citing works
ctDNA as a cancer biomarker: A broad overview
Pessoa, L. S., Heringer, M., & Ferrer, V. P. (2020) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2020.103109 · Cited by 303 · see citing works
Vaidya, J. S., Bulsara, M. K., Baum, M., Wenz, F. K., Massarut, S., Pigorsch, S. U., Alvarado, M. D., Douek, M., Saunders, C. M., Flyger, H. L., et al. (2020) · BMJ · doi:10.1136/bmj.m2836 · Cited by 291 · see citing works
Burden of Pancreatic Cancer: From Epidemiology to Practice
Khalaf, N., El-Serag, H. B., Abrams, H. R., & Thrift, A. P. (2021) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2020.02.054 · Cited by 308 · see citing works
The Roles of MicroRNA in Lung Cancer
Wu, K., Tsai, Y., Lien, C., Kuo, P., & Hung, J. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20071611 · Cited by 287 · see citing works
Bray, F., Parkin, D. M., Gnangnon, F. H. R., Tshisimogo, G., Peko, J. F., Adoubi, I., Assefa, M., Bojang, L., Awuah, B., Koulibaly, M., et al. (2022) · The Lancet Oncology · doi:10.1016/s1470-2045(22)00270-4 · Cited by 304 · see citing works
Self-citationWang, S., Zheng, R., Li, J., Zeng, H., Li, L., Chen, R., Sun, K., Han, B., Bray, F., Wei, W., et al. (2024) · The Lancet. Gastroenterology & hepatology · doi:10.1016/s2468-1253(23)00366-7 · Cited by 304 · see citing works
Self-citationRecent Patterns and Trends in Global Prostate Cancer Incidence and Mortality: An Update
Schafer, E. J., Laversanne, M., Sung, H., Soerjomataram, I., Briganti, A., Dahut, W. L., Bray, F., & Jemal, A. (2024) · European Urology · doi:10.1016/j.eururo.2024.11.013 · Cited by 283 · see citing works
Self-citationLiquid biopsies: Potential and challenges
Heidrich, I., Ačkar, L., Mohammadi, P. M., & Pantel, K. (2020) · International Journal of Cancer · doi:10.1002/ijc.33217 · Cited by 284 · see citing works
Multifunctional phototheranostic nanomedicine for cancer imaging and treatment
Gao, D., Guo, X., Zhang, X., Chen, S., Wang, Y., Chen, T., Huang, G. J., Gao, Y. F., Tian, Z., & Yang, Z. (2019) · Materials Today Bio · doi:10.1016/j.mtbio.2019.100035 · Cited by 274 · see citing works
Trends in cervical cancer incidence in sub-Saharan Africa
Jedy-Agba, E. E., Joko-Fru, W. Y., Liu, B., Buziba, N. G., Borok, M. Z., Korir, A., Masamba, L. P. L., Manraj, S. S., Finesse, A., Wabinga, H., et al. (2020) · British Journal of Cancer · doi:10.1038/s41416-020-0831-9 · Cited by 271 · see citing works
Self-citationDietary fat, bile acid metabolism and colorectal cancer
Ocvirk, S., & O’Keefe, S. J. (2020) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2020.10.003 · Cited by 263 · see citing works
Gut bacteria identified in colorectal cancer patients promote tumourigenesis via butyrate secretion
Okumura, S., Konishi, Y., Narukawa, M., Sugiura, Y., Yoshimoto, S., Arai, Y., Sato, S., Yoshida, Y., Tsuji, S., Uemura, K., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-25965-x · Cited by 264 · see citing works
Strickler, J. H., Cercek, A., Siena, S., André, T., Ng, K., Van Cutsem, E., Wu, C., Paulson, A. S., Hubbard, J. M., Coveler, A. L., et al. (2023) · The Lancet Oncology · doi:10.1016/s1470-2045(23)00150-x · Cited by 259 · see citing works
Targeted therapy for head and neck cancer: signaling pathways and clinical studies
Li, Q., Tie, Y., Alu, A., Ma, X., & Shi, H. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-01297-0 · Cited by 269 · see citing works
Artificial Intelligence in Dermatology Image Analysis: Current Developments and Future Trends
Li, Z., Koban, K. C., Schenck, T. L., Giunta, R. E., Li, Q., & Sun, Y. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11226826 · Cited by 279 · see citing works
Biomarkers in Colorectal Cancer: Current Research and Future Prospects
Ogunwobi, O. O., Mahmood, F., & Akingboye, A. A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21155311 · Cited by 251 · see citing works
Role of nano-selenium in health and environment
Kumar, A., & Prasad, K. S. (2020) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2020.11.004 · Cited by 250 · see citing works
Thomas, A., Necchi, A., Muneer, A., Tobias‐Machado, M., Tran, A. T. H., Rompuy, A. V., Spiess, P. E., & Albersen, M. (2021) · Nature Reviews Disease Primers · doi:10.1038/s41572-021-00246-5 · Cited by 261 · see citing works
Loret, N., Denys, H. G., Tummers, P., & Berx, G. (2019) · Cancers · doi:10.3390/cancers11060838 · Cited by 241 · see citing works
Healthy Lifestyle and Cancer Risk: Modifiable Risk Factors to Prevent Cancer
Marino, P., Mininni, M., Deiana, G., Marino, G., Divella, R., Bochicchio, I., Giuliano, A., Lapadula, S., Lettini, A. R., & Sanseverino, F. (2024) · Nutrients · doi:10.3390/nu16060800 · Cited by 279 · see citing works
Overview of skin cancer types and prevalence rates across continents
Roky, A. H., Islam, M. M., Ahasan, A. M. F., Mostaq, M. S., Mahmud, M. Z., Amin, M. N., & Mahmud, M. A. (2025) · Cancer Pathogenesis and Therapy · doi:10.1016/j.cpt.2024.08.002 · Cited by 239 · see citing works
Sharma, R., Aashima, A., Nanda, M., Fronterrè, C., Sewagudde, P., Ssentongo, A. E., Yenney, K., Arhin, N. D., Oh, J. S., Amponsah‐Manu, F., et al. (2022) · Frontiers in Public Health · doi:10.3389/fpubh.2022.839835 · Cited by 244 · see citing works
The Influence of Lung Microbiota on Lung Carcinogenesis, Immunity, and Immunotherapy
Ramírez-Labrada, A., Isla, D., Artal, A., Arias, M. A., Rezusta, A., Pardo, J., & Gálvez, E. M. (2020) · Trends in cancer · doi:10.1016/j.trecan.2019.12.007 · Cited by 234 · see citing works
Addressing the worldwide hepatocellular carcinoma: epidemiology, prevention and management
Samant, H. V., Amiri, H. S., & Zibari, G. B. (2021) · Journal of Gastrointestinal Oncology · doi:10.21037/jgo.2020.02.08 · Cited by 234 · see citing works
Gilles, H., Garbutt, T., & Landrum, J. (2022) · Critical Care Nursing Clinics of North America · doi:10.1016/j.cnc.2022.04.004 · Cited by 226 · see citing works
Demirtaş, C. Ö., D’Alessio, A., Rimassa, L., Sharma, R., & Pinato, D. J. (2021) · JHEP Reports · doi:10.1016/j.jhepr.2021.100347 · Cited by 230 · see citing works
Current status of immune checkpoint inhibitors for gastric cancer
Kono, K., Nakajima, S., & Mimura, K. (2020) · Gastric Cancer · doi:10.1007/s10120-020-01090-4 · Cited by 220 · see citing works
ACPred: A Computational Tool for the Prediction and Analysis of Anticancer Peptides
Schaduangrat, N., Nantasenamat, C., Prachayasittikul, V., & Shoombuatong, W. (2019) · Molecules · doi:10.3390/molecules24101973 · Cited by 220 · see citing works
Badwelan, M., Muaddi, H. A., Ahmed, A., Lee, K. T., & Tran, S. D. (2023) · Current Oncology · doi:10.3390/curroncol30040283 · Cited by 235 · see citing works
MoS2-based nanocomposites for cancer diagnosis and therapy
Wang, J.-L., Sui, L., Huang, J., Miao, L., Nie, Y., Wang, K., Yang, Z., Huang, Q., Gong, X., Nan, Y., et al. (2021) · Bioactive Materials · doi:10.1016/j.bioactmat.2021.04.021 · Cited by 215 · see citing works
Metabolic glycan labelling for cancer-targeted therapy
Wang, H., & Mooney, D. J. (2020) · Nature Chemistry · doi:10.1038/s41557-020-00587-w · Cited by 220 · see citing works
Zheng, X., Weigert, A., Reu, S., Günther, S., Mansouri, S., Bassaly, B., Gattenlöhner, S., Grimminger, F., Pullamsetti, S. S., Seeger, W., et al. (2020) · Cancer Research · doi:10.1158/0008-5472.can-20-0069 · Cited by 218 · see citing works
Microsatellite instability in Gastric Cancer: Between lights and shadows
Puliga, E., Corso, S., Pietrantonio, F., & Giordano, S. (2021) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2021.102175 · Cited by 215 · see citing works
Lee, P.-C., Wu, C.-J., Hung, Y.-W., Lee, C. J., Chi, C.-T., Lee, I.-C., Yu-Lun, K., Chou, S.-H., Luo, J.-C., Hou, M.-C., et al. (2022) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2022-004779 · Cited by 217 · see citing works
Teixeira, A. F., ten Dijke, P., & Zhu, H. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00605 · Cited by 210 · see citing works
Oliver, A. L. (2022) · Surgical Clinics of North America · doi:10.1016/j.suc.2021.12.001 · Cited by 215 · see citing works
Adaptive Mechanisms of Tumor Therapy Resistance Driven by Tumor Microenvironment
Wu, P., Gao, W. Q., Su, M., Nice, E. C., Zhang, W., Lin, J., & Xie, N. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.641469 · Cited by 212 · see citing works
Seretis, A., Cividini, S., Markozannes, G., Tseretopoulou, X., López, D. S., Ntzani, E., & Tsilidis, K. K. (2019) · Scientific Reports · doi:10.1038/s41598-019-45014-4 · Cited by 212 · see citing works
- Authors
- Ferlay, J., Colombet, M., Soerjomataram, I., Mathers, C., Parkin, D. M., Piñeros, M., Znaor, A., & Bray, F.
- Affiliations
- Centre international de recherche sur le cancer (FR)
- World Health Organization (CH)
- University of Oxford (GB)
- Corresponding author
- Ferlay, J.
- Venue
- International Journal of Cancer
- Publisher
- Wiley
- Published
- 2018-12-06
- Volume
- 144
- Issue
- 8
- Pages
- 1941-1953
- ISSN
- 0020-7136 (ISSN-L)
- 1097-0215
- OpenAlex
- W2895926103
- Cited by
- 7,553
- References
- 16
- Citations by year
- 2026: 251 · 2025: 513 · 2024: 812 · 2023: 978 · 2022: 1340 · 2021: 1805 · 2020: 1403 · 2019: 425 · 2018: 13 · 2016: 1 · 2015: 1 · 2014: 1 · 2012: 1
- FWCI
- 344.49
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- International Journal of Cancer (publishedVersion)
- PubMed (publishedVersion)
- Funders
- World Health Organization
- University of Leicester
- National Cancer Institute
- Topics
- Health Sciences › Medicine › Oncology › Global Cancer Incidence and Screening
- Health Sciences › Medicine › Oncology › Colorectal Cancer Screening and Detection
- Health Sciences › Medicine › Reproductive Medicine › Science, Research, and Medicine
- Keywords
- cancer incidence, cancer mortality, non-melanoma skin cancer, uncertainty intervals, source bias, world regions
- MeSH terms
- Global Burden of Disease, Adolescent, Adult, Aged, Aged, 80 and over, Cause of Death, Child, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Male, Middle Aged, Neoplasms, Risk Factors, Incidence, Survival Rate, Databases, Factual, Sex Distribution, Young Adult
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