Apolipoprotein E isoforms and lipoprotein metabolism

Phillips, Michael C.·2014·IUBMB Life

Cited by (328)

Items 101–200 of 328

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  2. A novel amphipathic cell-penetrating peptide based on the N-terminal glycosaminoglycan binding region of human apolipoprotein E
    Takashi Ohgita, Yuki Takechi‐Haraya, Ryo Nadai, Mana Kotani, Yuki Tamura, Nishikiori Karin, Kazuchika Nishitsuji, Kenji Uchimura, Koki Hasegawa, Kumiko Sakai‐Kato et al. · 2018 · Biochimica et Biophysica Acta (BBA) - Biomembranes
  3. Lipid-lowering response in subjects with the p.(Leu167del) mutation in the APOE gene
    Ana M. Bea, Itziar Lamíquiz-Moneo, Victoria Marco-Benedí, Rocío Mateo‐Gállego, Sofía Pérez‐Calahorra, Estíbaliz Jarauta, César Martı́n, Ana Cenarro, Fernando Civeira · 2019 · Atherosclerosis
  4. APOE Genotype Modifies the Plasma Oxylipin Response to Omega-3 Polyunsaturated Fatty Acid Supplementation in Healthy Individuals
    Rasha N.M. Saleh, Annette L. West, Annika Irmgard Ostermann, Nils Helge Schebb, Philip C. Calder, Anne Marie Minihane · 2021 · Frontiers in Nutrition
  5. Bioactive Compound Screen for Pharmacological Enhancers of Apolipoprotein E in Primary Human Astrocytes
    Gina M. Finan, Ronald B. Realubit, Sungkwon Chung, Dieter Lütjohann, Nan Wang, John R. Cirrito, Charles Karan, Taewan Kim · 2016 · Cell chemical biology
  6. Relationship Between the ApoE Gene Polymorphism and Type 2 Diabetes Mellitus Complications
    C. Gao, Xiaolin Fu, Qinying Chu, Jian-Hua Li, Gang-Ming Shu · 2021 · Genetic Testing and Molecular Biomarkers
  7. Total Cholesterol and APOE -Related Risk for Alzheimer’s Disease in the Alzheimer’s Disease Neuroimaging Initiative
    Michelle M. Dunk, Ira Frahmand Driscoll, Alzheimer’s Disease Neuroimaging Initiative · 2021 · Journal of Alzheimer s Disease
  8. Genetic Variants at the APOE Locus Predict Cardiometabolic Traits and Metabolic Syndrome: A Taiwan Biobank Study
    Kuan-Hung Yeh, Hsiang‐Lin Wan, Ming‐Sheng Teng, Hsin‐Hua Chou, Lung‐An Hsu, Yu‐Lin Ko · 2022 · Genes
  9. Therapeutic approaches of nutraceuticals in the prevention of Alzheimer's disease
    Surya Nath Pandey, Gurfateh Singh, Bhupesh Chander Semwal, Gaurav Gupta, Khalid Saad Alharbi, Waleed Hassan Almalki, Mohammed Albratty, Asim Najmi, Abdulkarim M. Meraya · 2022 · Journal of Food Biochemistry
  10. How Research on Human Progeroid and Antigeroid Syndromes Can Contribute to the Longevity Dividend Initiative
    Fuki Marie Hisama, Junko Oshima, George M. Martin · 2016 · Cold Spring Harbor Perspectives in Medicine
  11. Apolipoprotein E in Alzheimer’s Disease: Focus on Synaptic Function and Therapeutic Strategy
    Longjie Qu, Shuai Xu, Zhen Lan, Shuang Fang, Yun Xu, Xiaolei Zhu · 2024 · Molecular Neurobiology
  12. The effects of genetic polymorphisms of APOE on circulating lipid levels in middle-aged and elderly chinese Fujian Han population: toward age- and sex-personalized management
    Xiaofeng Liu, Qingwen Lin, Kengna Fan, Minjie Tang, Weiqing Zhang, Bin Yang, Qishui Ou · 2021 · Lipids in Health and Disease
  13. Syncytiotrophoblast‐derived extracellular vesicles carry apolipoprotein‐E and affect lipid synthesis of liver cells in vitro
    Chiara Tersigni, Muhammad Furqan Bari, Shijei Cai, Wei Zhang, Neva Kandžija, Alice Buchan, Fabrizio Miranda, Nicoletta Di Simone, Christopher W.G. Redman, Claire C. Bastie et al. · 2021 · Journal of Cellular and Molecular Medicine
  14. Molecular modeling of apoE in complexes with Alzheimer’s amyloid-β fibrils from human brain suggests a structural basis for apolipoprotein co-deposition with amyloids
    Emily Lewkowicz, Mari N. Nakamura, Michael J. Rynkiewicz, Olga Gursky · 2023 · Cellular and Molecular Life Sciences
  15. Apolipoprotein E E3/E4 genotype is associated with an increased risk of type 2 diabetes mellitus complicated with coronary artery disease
    Wenhao Chen, Bin Li, Hao Wang, Guoliang Wei, Kehui Chen, Weihong Wang, Shen Wang, Yuanliang Liu · 2024 · BMC Cardiovascular Disorders
  16. Multiple Roles of Apolipoprotein E4 in Oxidative Lipid Metabolism and Ferroptosis During the Pathogenesis of Alzheimer’s Disease
    Parisa Faraji, Hartmut Kühn, Shahin Ahmadian · 2024 · Journal of Molecular Neuroscience
  17. Association between APOE polymorphisms and lipid profile in Mexican Amerindian population
    José Jaime Martínez‐Magaña, Alma Delia Genis Mendoza, Carlos Alfonso Tovilla‐Zárate, Thelma Beatriz González‐Castro, Isela Esther Juárez‐Rojop, Yazmín Hernández‐Díaz, Angélica Graciela Martínez-Hernández, Humberto Garcia‐Ortíz, Lorena Orozco, María Lilia López‐Narváez et al. · 2019 · Molecular Genetics & Genomic Medicine
  18. Apolipoprotein E2 modulates cell cycle function to promote proliferation in pancreatic cancer cells via regulation of the c-Myc–p21Waf1 signalling pathway
    Shaoxia Du, Hui Wang, Jun Cai, Runling Ren, Wen‐Wen Zhang, Wei Wei, Xiaohong Shen · 2020 · Biochemistry and Cell Biology
  19. Effect of Aluminum-Maltolate on the Content of Aβ Protein and the Expression of ApoER2, VLDLRs, and LRP1 in PC12-ApoE4 Cells
    Ting Zhang, Shan Wang, Q. L. Niu · 2019 · Neurotoxicity Research
  20. Impact of New Drugs for Therapeutic Intervention in Alzheimer’s Disease
    Jordi Olloquequi, Miren Ettcheto, Amanda C. Cano, Elena Sánchez‐López, Marina Carrasco, Triana Espinosa-Jiménez, Carlos Beas‐Zárate, Graciela Gudiño‐Cabrera, Mónica E. Ureña‐Guerrero, Ester Verdaguer et al. · 2022 · Frontiers in Bioscience-Landmark
  21. Interactive effects of C-reactive protein levels on the association between APOE variants and triglyceride levels in a Taiwanese population
    Semon Wu, Lung‐An Hsu, Ming‐Sheng Teng, Jeng-Feng Lin, Hsin‐Hua Chou, Ming‐Cheng Lee, WU Yi-ming, Cheng-Wen Su, Yu‐Lin Ko · 2016 · Lipids in Health and Disease
  22. Cell-free, high-density lipoprotein–specific phospholipid efflux assay predicts incident cardiovascular disease
    Masaki Sato, Edward B. Neufeld, Martin Peter Playford, Lei Yu, Alexander V. Sorokin, Angel M. Aponte, Lita A. Freeman, Scott M. Gordon, Amit Kumar Dey, Kianoush Jeiran et al. · 2023 · Journal of Clinical Investigation
  23. Impact of Apolipoprotein E ε4 in Alzheimer’s Disease: A Meta-Analysis of Voxel-Based Morphometry Studies
    Madison Bailey, Zlatomira G. Ilchovska, Akram A. Hosseini, JeYoung Jung · 2024 · Journal of Clinical Neurology
  24. Rare thrombophilic conditions
    Gian Luca Salvagno, Chiara Pavan, Giuseppe Lippi · 2018 · Annals of Translational Medicine
  25. Ameliorative Effects by Hexagonal Boron Nitride Nanoparticles against Beta Amyloid Induced Neurotoxicity
    Nursah Aydin, Hasan Türkez, Özlem Özdemir Tozlu, Mehmet Enes Arslan, Mehmet Yavuz, Erdal Sönmez, Özgür Fırat Özpolat, Ivana Cacciatore, Antonio Di Stefano, Adil Mardinoğlu · 2022 · Nanomaterials
  26. Searching the Linkage between High Fat Diet and Alzheimer′s Disease: A Debatable Proof Stand for Ketogenic Diet to Alleviate Symptoms of Alzheimer′s Patient with APOE ε4 Allele
    Md. Sahab Uddin, Anamul Haque · 2016 · Journal of Neurology & Neurophysiology
  27. Genetic factors of cervical spondylotic myelopathy-a systemic review
    Guohua Wang, Yong Bing Cao, Tianding Wu, Chunyue Duan, Jianhuang Wu, Jianzhong Hu, Hongbin Lü · 2017 · Journal of Clinical Neuroscience
  28. Levels of Angiotensin-Converting Enzyme and Apolipoproteins Are Associated with Alzheimer’s Disease and Cardiovascular Diseases
    Xu, Chun, Garcia, Debra, Lu, Yongke, Ozuna, Kaysie, Adjeroh, Donald A., Wang, Kesheng, on behalf of the Alzheimer’s Disease Neuroimaging Initiative · 2021 · Cells
  29. Somatic Mutations and Alzheimer’s Disease
    Jocelyn S. Downey, J. C. Lam, Victor Li, I. Gozes · 2022 · Journal of Alzheimer's Disease
  30. Genetics of ischemic stroke functional outcome
    Troy Carnwath, Stacie L Demel, Charles Joseph Prestigiacomo · 2024 · Journal of Neurology
  31. Eco-Aging: stem cells and microbes are controlled by aging antagonist FoxO
    Benedikt M. Mortzfeld, Thomas C. G. Bosch · 2017 · Current Opinion in Microbiology
  32. Host Defence Cryptides from Human Apolipoproteins: Applications in Medicinal Chemistry
    Rosa Gaglione, Elio Pizzo, Eugenio Notomista, César de la Fuente‐Núñez, Angela Arciello · 2020 · Current Topics in Medicinal Chemistry
  33. Apolipoprotein E gene polymorphism and renal function are associated with apolipoprotein E concentration in patients with chronic kidney disease
    Monika Czaplińska, Agnieszka Ćwiklińska, Monika Sakowicz‐Burkiewicz, Ewa Wieczorek, Agnieszka Kuchta, Robert G. Kowalski, Barbara Kortas‐Stempak, Alicja Maria Dębska-Ślizień, Maciej Jankowski, Ewa Król · 2019 · Lipids in Health and Disease
  34. The cross-talk between ApoE and Tau protein in Alzheimer’s disease
    Subashchandrabose Chinnathambi, Murugappan Kumarappan, Madhura Chandrashekar · 2024 · Advances in protein chemistry and structural biology
  35. Lipoprotein Lipase: Structure, Function, and Genetic Variation
    Shehan D. Perera, Jian Wang, Adam D. McIntyre, Robert Alexander Hegele · 2025 · Genes
  36. APOE Lipoprotein Particles: Pathophysiology, Therapy, and the Crosstalk in Alzheimer’s Disease and Cardiovascular Disease
    Чан Лю, Juan Liu, Yanyang Wang, Shang-Fu Xu, Li-Mei Yu · 2025 · Molecular Neurobiology
  37. Association between polymorphisms in the promoter region of the apolipoprotein E (APOE) gene and Alzheimer’s disease: a meta-analysis
    Xiao, Hanyan, Yifeng Gao, Lei Liu, Yan Li · 2017 · EXCLI journal
  38. Apolipoprotein E DNA methylation and posttraumatic stress disorder are associated with plasma ApoE level: A preliminary study
    David A. Nielsen, Catherine J. Spellicy, Mark J. Harding, David P. Graham · 2018 · Behavioural Brain Research
  39. APOE Genotype Differentially Modulates Plasma Lipids in Healthy Older Individuals, with Relevance to Brain Health
    Matthew Wai Kin Wong, Nady Braidy, John Crawford, Russell Pickford, Fei Song, Karen A. Mather, John Attia, Henry Brodaty, Perminder Singh Sachdev, Anne Poljak · 2019 · Journal of Alzheimer s Disease
  40. Dietary cadmium exposure causes elevation of blood ApoE with triglyceride level in mice
    Haitao Liu, Yanwei Wang, Zhen Ren, Xingqi Ji, Frank Peprah Addai, Xiu-Wen Zhang, Shuya Dai, Yang Zhou, Jie Gu, Haifeng Shi · 2020 · BioMetals
  41. Genetics of Triglyceride-Rich Lipoproteins Guide Identification of Pharmacotherapy for Cardiovascular Risk Reduction
    Aleesha Shaik, Robert S. Rosenson · 2021 · Cardiovascular Drugs and Therapy
  42. Effect of PCSK9 inhibition with evolocumab on lipoprotein subfractions in familial dysbetalipoproteinemia (type III hyperlipidemia)
    Elisa Waldmann, WU Li-ya, Kristina Busygina, Julia Altenhofer, Kerstin Henze, Alexander Folwaczny, Klaus Georg Parhofer · 2022 · PLoS ONE
  43. Impact of Apolipoprotein E Variants: A Review of Naturally Occurring Variants and Clinical Features
    Matsunaga, Akira, Saito, Takao · 2025 · Journal of Atherosclerosis and Thrombosis
  44. Association of APOE genotype with lipid profiles and type 2 diabetes mellitus in a Korean population
    Jung Yeon Seo, Byeong Ju Youn, Hyun Sub Cheong, Hyoung Doo Shin · 2021 · Genes & Genomics
  45. Development of a Melting Curve-Based Allele-Specific PCR of Apolipoprotein E (APOE) Genotyping Method for Genomic DNA, Guthrie Blood Spot, and Whole Blood
    Chia‐Hsiang Chen · 2016 · PLoS ONE
  46. Association between apolipoprotein E gene polymorphism and nonalcoholic fatty liver disease in Southern China: A case‐control study
    Sudong Liu, Ruiqiang Weng, Xiaodong Gu, Lihai Li, Zhixiong Zhong · 2021 · Journal of Clinical Laboratory Analysis
  47. Relationship between Apolipoprotein E Genotype and Lipoprotein Profile in Patients with Coronary Heart Disease
    Yahui Lin, Qiong Yang, Zhaohui Liu, Baoman Su, XU Fen, Yang Li, Jinsuo Kang, Zhou Zhou · 2022 · Molecules
  48. Simultaneous Mass Spectrometry-Based Apolipoprotein Profiling and Apolipoprotein E Phenotyping in Patients with ASCVD and Mild Cognitive Impairment
    Begcevic Brkovic, Ilijana, Zöhrer, Benedikt, Scholz, Markus, Reinicke, Madlen, Dittrich, Julia, Kamalsada, Surab, Baber, Ronny, Beutner, Frank, Teren, Andrej, Engel, Christoph et al. · 2022 · Nutrients
  49. Isoform- and cell-state-specific APOE homeostasis and function
    Lindner, Karina, Gavin, Anne-Claude · 2024 · Neural Regeneration Research
  50. Insights into the roles of Apolipoprotein E in adipocyte biology and obesity
    Chung‐Lin Jiang, Fu‐Jung Lin · 2024 · International Journal of Obesity
  51. A Diet Rich in Docosahexaenoic Acid Restores Liver Arachidonic Acid and Docosahexaenoic Acid Concentrations in Mice Homozygous for the Human Apolipoprotein E ε4 Allele
    Raphaël Chouinard‐Watkins, Anthony Pinçon, Jean-Denis Coulombe, Riley Spencer, Laurence Massenavette, Mélanie Plourde · 2016 · Journal of Nutrition
  52. TMT-based proteomics analysis reveals the efficacy of jiangzhuo formula in improving the lipid profiles of dyslipidemia rats
    Linlin Pan, Yuan Tian, Haiyang Sun, Yao Wang, Gui‐Rong Liu · 2020 · Journal of Ethnopharmacology
  53. An association of CSF apolipoprotein E glycosylation and amyloid-beta 42 in individuals who carry the APOE4 allele
    Cristiana Meuret, Yue-Ming Hu, Sabrina Smadi, Mikaila A Bantugan, Haotian Xian, Ashley E. Martinez, R. Krauss, Qiu-Lan Ma, D. Nedelkov, Hussein N. Yassine · 2023 · Alzheimer's Research & Therapy
  54. Apolipoprotein E levels and apolipoprotein E genotypes in incident cardiovascular disease risk in subjects of the Prevention of Renal and Vascular End-stage disease study
    James P. Corsetti, Ron T. Gansevoort, Stephan J. L. Bakker, Robin P. F. Dullaart · 2016 · Journal of clinical lipidology
  55. Apolipoprotein E ε4 allele is associated with vascular cognitive impairment no dementia in Chinese population
    Yue Han, Aihong Zhou, Fangyu Li, Qi Wang, Lingzhi Xu, Jianping Jia · 2019 · Journal of the Neurological Sciences
  56. A Synthetic Snake-Venom-Based Tripeptide Protects PC12 Cells from the Neurotoxicity of Acrolein by Improving Axonal Plasticity and Bioenergetics
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  57. Relevance of lipoproteins, membranes, and extracellular vesicles in understanding C-reactive protein biochemical structure and biological activities
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  58. Trans‐ethnic genomic informed risk assessment for Alzheimer's disease: An International Hundred K+ Cohorts Consortium study
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  59. Advances in Understanding and Managing Alzheimer's Disease: From Pathophysiology to Innovative Therapeutic Strategies
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  60. Mechanism of Lipid Binding of Human Apolipoprotein E3 by Hydrogen/Deuterium Exchange/Mass Spectrometry and Fluorescence Polarization
    Charina S. Fabilane, Patricia N. Nguyen, Roy V. Hernandez, Sasidhar N. Nirudodhi, Mai Duong, Claudia S. Maier, Vasanthy Narayanaswami · 2016 · Protein and Peptide Letters
  61. Influence of Partial External Biliary Diversion on the Lipid Profile in Children With Progressive Familial Intrahepatic Cholestasis
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  62. Cellular Uptake and Clearance of Oxidatively-modified Apolipoprotein E3 by Cerebral Cortex Endothelial Cells
    Siobanth Cruz, Vasanthy Narayanaswami · 2019 · International Journal of Molecular Sciences
  63. Analysis of early effects of human APOE isoforms on Alzheimer’s disease and type III hyperlipoproteinemia pathways using knock-in rat models with humanized APP and APOE
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  64. Apolipoprotein E2 inhibits mitochondrial apoptosis in pancreatic cancer cells through ERK1/2/CREB/BCL-2 signaling
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  65. Investigating Effects of Plasma Apolipoprotein E on Ischemic Heart Disease Using Mendelian Randomization Study
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  66. Lipoprotein Metabolism, Protein Aggregation, and Alzheimer’s Disease: A Literature Review
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  67. Association of Apolipoprotein E (APOE) Polymorphisms With Serological Lipid and Inflammatory Markers
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  68. Differentially expressed plasma proteins of β-thalassemia/hemoglobin E patients in response to curcuminoids/vitamin E antioxidant cocktails
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  69. A Combination of Single Nucleotide Polymorphisms is Associated with the Interindividual Variability of Cholesterol Bioavailability in Healthy Adult Males
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  70. Impact of APOE Alleles-by-Diet Interactions on Glycemic and Lipid Features– A Cross-Sectional Study of a Cohort of Type 2 Diabetes Patients from Western Mexico: Implications for Personalized Medicine
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  71. Suppression of CNS APOE4 Expression by miRNAs Delivered by the S2 AAVrh.10 Capsid-Modified AAV Vector
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  72. ApoE2-DARPin fusion proteins enable selective RNA transfer to CD8 T cells by lipid nanoparticles
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  74. Genetic Lipid Disorders Associated with Atherosclerotic Cardiovascular Disease
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  75. Features of Lipid Metabolism in Humanized ApoE Knockin Rat Models
    Yang Wu, Gem Johnson, Fujie Zhao, Yin Wu, Guojun Zhao, Andrew John Brown, Shaojin You, Ming‐Hui Zou, Ping Song · 2021 · International Journal of Molecular Sciences
  76. Polymorphisms of the apolipoprotein E gene affect response to atorvastatin therapy in acute ischemic stroke
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  77. Blood Pressure and Statin Effects on Cognition: a Review
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  78. Apolipoprotein E2 Promotes the Migration and Invasion of Pancreatic Cancer Cells via Activation of the ERK1/2 Signaling Pathway
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  79. Mouse and human microglial phenotypes in Alzheimer’s disease are controlled by amyloid plaque phagocytosis through Hif1α
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  80. Apolipoprotein E E3/E4 genotype is associated with an increased risk of coronary atherosclerosis in patients with hypertension
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  81. The impact of PPARγ and ApoE gene polymorphisms on susceptibility to diabetic kidney disease in type 2 diabetes mellitus: a meta-analysis
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  84. The Apolipoprotein E neutralizing antibody inhibits SARS‐CoV‐2 infection by blocking cellular entry of lipoviral particles
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  85. Association of apolipoprotein E genotype with outcome in hospitalized ischemic stroke patients
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  86. Lauric Acid Beneficially Modulates Apolipoprotein Secretion and Enhances Fatty Acid Oxidation via PPARα-dependent Pathways in Cultured Rat Hepatocytes
    Arunima Sakunthala, Thankappan Rajamohan · 2018 · Journal of Exploratory Research in Pharmacology
  87. Ordered opening of LDL receptor binding domain of human apolipoprotein E3 revealed by hydrogen/deuterium exchange mass spectrometry and fluorescence spectroscopy
    Liping Yang, Roy V. Hernandez, Tuyen Ngoc Tran, Sasidhar N. Nirudodhi, Wendy H.J. Beck, Claudia S. Maier, Vasanthy Narayanaswami · 2018 · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
  88. ApoE Isoforms Inhibit Amyloid Aggregation of Proinflammatory Protein S100A9
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  89. Quantitative and Kinetic Proteomics Reveal ApoE Isoform-dependent Proteostasis Adaptations in Mouse Brain
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  90. Increased cerebrospinal fluid and plasma apoE glycosylation is associated with reduced levels of Alzheimer’s disease biomarkers
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  93. Isoform‐specific modification of apolipoprotein E by 4‐hydroxynonenal : protective role of apolipoprotein E3 against oxidative species
    Muhammad I. Abeer, Abbas Abdulhasan, Zahraa Haguar, Vasanthy Narayanaswami · 2023 · FEBS Journal
  94. Role of the APOE polymorphism in carotid and lower limb revascularization: A prospective study from Southern Italy
    Sandra Mastroianno, Giuseppe Di Stolfo, Davide Seripa, Michele Antonio Pacilli, Giulia Paroni, Carlo Coli, Maria Urbano, Carmela d’Arienzo, Carolina Gravina, Domenico Rosario Potenza et al. · 2017 · PLoS ONE
  95. Identifying the Lipidomic Effects of a Rare Loss-of-Function Deletion in ANGPTL3
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  96. Human ApoE2 Endows Stronger Contractility in Rat Cardiomyocytes Enhancing Heart Function
    Yang Wu, Fujie Zhao, Venkata N. L. R. Sure, Abdulgafar Dare Ibrahim, Changjiang Yu, Sean Michael Carr, Ping Song · 2023 · Cells
  97. Apolipoprotein E E3/E4 genotype is associated with an increased risk of premature coronary artery disease
    Youqian Li, Wei Zhong, Changjing Huang, Junyin Peng, Hanlin Li · 2024 · BMC Cardiovascular Disorders
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  99. A proteomics perspective on 2 years of high-intensity training in horses: a pilot study
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