The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Bioactive sol‐gel foams for tissue repair
Abstract
Bioactive glasses are known to have the ability to regenerate bone, but their use has been restricted mainly to powder, granules, or small monoliths. This work reports on the development of sol‐gel foams with potential applications as bone graft implants or as templates for the in vitro synthesis of bone tissue for transplantation. These bioactive foams exhibit a hierarchical structure with interconnected macropores (10–500 μm) and a mesoporous framework typical of gel–glasses (pores of 2–50 nm). The macroporous matrixes were produced through a novel route that comprises foaming of sol‐gel systems. Three glass systems were tested to verify the applicability of this manufacturing route, namely SiO 2, SiO 2‐CaO, and SiO 2‐CaO‐P 2 O 5. This new class of material combines large pores to support vascularization and 3‐D tissue growth with the ability that bioactive materials have to provide bone‐bonding and controlled release of ionic biologic stimuli to promote bone cell proliferation by gene activation. © 2001 Wiley Periodicals, Inc. J Biomed Mater Res 59: 340–348, 2002
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Cites
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Cited by
Bioceramics: Past, present and for the future
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Bone biomaterials and interactions with stem cells
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Sol–gel silica-based biomaterials and bone tissue regeneration
Arcos, D., & Vallet-Regí, M. (2010) · Acta Biomaterialia · doi:10.1016/j.actbio.2010.02.012 · Cited by 579
Confinement effects on freezing and melting
Christenson, H. K. (2001) · Journal of Physics: Condensed Matter · doi:10.1088/0953-8984/13/11/201 · Cited by 567
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Metadata
- Authors
- Sepulveda, P., Jones, J. R., & Hench, L. L.
- Venue
- Journal of Biomedical Materials Research
- Publisher
- Wiley
- Published
- 2001-11
- Volume
- 59
- Issue
- 2
- Pages
- 340-348
- ISSN
- 0021-9304 (ISSN-L)
- 1097-4636
- OpenAlex
- W2151846978
- Cited by
- 441
- References
- 19
- FWCI
- 12.63
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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