The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
SPARC and tumor growth: Where the seed meets the soil?
Abstract
Matricellular proteins mediate interactions between cells and their extracellular environment. This functional protein family includes several structurally unrelated members, such as SPARC, thrombospondin 1, tenascin C, and osteopontin, as well as some homologs of these proteins, such as thrombospondin 2 and tensascin X. SPARC, a prototypic matricellular protein, and its homolog hevin, have deadhesive effects on cultured cells and have been characterized as antiproliferative factors in some cellular contexts. Both proteins are produced at high levels in many types of cancers, especially by cells associated with tumor stroma and vasculature. In this Prospect article we summarize evidence for SPARC and hevin in the regulation of tumor cell growth, differentiation, and metastasis, and we propose that matricellular proteins such as these perform critical functions in desmoplastic responses of tumors that culminate in their dissemination and eventual colonization of other sites. © 2004 Wiley‐Liss, Inc.
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Cites
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The pathogenesis of cancer metastasis: the ‘seed and soil’ hypothesis revisited
Fidler, I. J. (2003) · Nature Reviews Cancer · doi:10.1038/nrc1098 · Cited by 4,686
Obesity-induced inflammatory changes in adipose tissue
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Peripheral Blood Fibrocytes: Differentiation Pathway and Migration to Wound Sites
Abe, R., Donnelly, S. C., Peng, T., Bucala, R., & Metz, C. N. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.12.7556 · Cited by 967 · cited 1×
“The former is a mesenchymal cell that can be cultured from peripheral blood and demonstrates monocytic and fibroblastic characteristics [Abe et al., 2001].”
BackgroundCancer cells compress intratumour vessels
Padera, T. P., Stoll, B. R., Tooredman, J. B., Capen, D., Tomaso, E. D., & Jain, R. K. (2004) · Nature · doi:10.1038/427695a · Cited by 857
Abnormalities of Basement Membrane on Blood Vessels and Endothelial Sprouts in Tumors
Baluk, P., Morikawa, S., Haskell, A., Mancuso, M., & McDonald, D. M. (2003) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)63540-7 · Cited by 528
Fibulins: a versatile family of extracellular matrix proteins
Timpl, R., Sasaki, T., Kostka, G., & Chu, M.-L. (2003) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1130 · Cited by 494
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Gene expression profiling of the tumor microenvironment during breast cancer progression
Ma, X.-J., Dahiya, S., Richardson, E., Erlander, M., & Sgroi, D. C. (2009) · Breast Cancer Research · doi:10.1186/bcr2222 · Cited by 629
Arnold, S. A., Rivera, L. B., Miller, A. F., Carbon, J. G., Dineen, S. P., Xie, Y., Castrillon, D. H., Sage, E. H., Puolakkainen, P., Bradshaw, A. D., et al. (2010) · Disease Models & Mechanisms · doi:10.1242/dmm.003228 · Cited by 118
Self-citationSPARC-null Mice Exhibit Lower Intraocular Pressures
Haddadin, R. I., Oh, D.-J., Kang, M. H., Filippopoulos, T., Gupta, M., Hart, L., Sage, E. H., & Rhee, D. J. (2009) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.08-2489 · Cited by 71
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Metadata
- Authors
- Framson, P. E., & Sage, E. H.
- Venue
- Journal of Cellular Biochemistry
- Publisher
- Wiley
- Published
- 2004-05-25
- Volume
- 92
- Issue
- 4
- Pages
- 679-690
- ISSN
- 0730-2312 (ISSN-L)
- 1097-4644
- OpenAlex
- W2088766801
- Cited by
- 249
- References
- 7
- FWCI
- 11.59
- Type
- journal article
- Language
- en
- Open access
- closed
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