The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Persistence of rhinovirus and enterovirus RNA after acute respiratory illness in children
Abstract
The persistence of rhinovirus and enterovirus RNAs was studied in the nasal secretions of children with acute expiratory wheezing (median age: 1.7 years). On admission, 84 samples from 161 (52%) children admitted to hospital were positive by reverse transcriptase‐polymerase chain reaction (RT‐PCR), which detects rhino‐ and enteroviruses simultaneously. Of the samples, 26 (16%) were positive for rhinovirus, 29 (18%) enterovirus and 29 (18%) nontypable rhino‐enterovirus. After 2 weeks, 16 of these 84 (19%) samples were still positive. Rhinovirus RNA remained positive in 13 of 26 (50%) cases, whereas enterovirus RNA remained positive only in 1 of 29 (3%) cases (P = 0.0001). Respiratory symptoms at 2 weeks or systemic glucocorticoid treatment during hospital stay were not related to the persistence of viral RNA. After 5 weeks, only one sample remained PCR‐positive. Thirteen of the 79 (16%) asymptomatic control children were PCR‐positive for respiratory picornavirus. Five of the 13 (38%) PCR‐positive children developed respiratory symptoms in the following week. The study shows that after the onset of symptomatic respiratory infection enterovirus RNA may take 2–3 weeks and rhinovirus RNA 5–6 weeks to disappear from nasal mucus. J. Med. Virol. 72:695–699, 2004. © 2004 Wiley‐Liss, Inc.
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Cites
Viruses and bacteria in the etiology of the common cold
Mäkelä, M. J., Puhakka, T., Ruuskanen, O., Leinonen, M., Saikku, P., Kimpimäki, M., Blomqvist, S., Hyypiä, T., & Arstila, P. (1998) · Journal of Clinical Microbiology · doi:10.1128/jcm.36.2.539-542.1998 · Cited by 768
Self-citationFrequency and natural history of rhinovirus infections in adults during autumn
Arruda, E., Pitkäranta, A., Witek, T. J., Doyle, C. A., & Hayden, F. G. (1997) · Journal of Clinical Microbiology · doi:10.1128/jcm.35.11.2864-2868.1997 · Cited by 346
Oral prednisone therapy in experimental rhinovirus infections
Gustafson, L. M., Proud, D., Hendley, J. O., Hayden, F. G., & Gwaltney, J. M. (1996) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(96)80077-7 · Cited by 122 · cited 2×
“Glucocorticoid treatment, which was received systemically by 49% and by inhalation by 7% of the children, has been shown to increase rhinovirus titres [Gustafson et al., 1996] and prolong the shedding of the virus from the nasopharynx of young adults [Puhakka et al., 1998].”
BackgroundThe common cold: effects of intranasal fluticasone propionate treatment
Puhakka, T., Mäkelä, M. J., Malmström, K., Uhari, M., Savolainen, J., Terho, E. O., Pulkkinen, M., & Ruuskanen, O. (1998) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(98)70301-x · Cited by 89 · cited 2×
“Glucocorticoid treatment, which was received systemically by 49% and by inhalation by 7% of the children, has been shown to increase rhinovirus titres [Gustafson et al., 1996] and prolong the shedding of the virus from the nasopharynx of young adults [Puhakka et al., 1998].”
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Cited by
Respiratory Viral Infections in Infants: Causes, Clinical Symptoms, Virology, and Immunology
Tregoning, J. S., & Schwarze, J. (2010) · Clinical Microbiology Reviews · doi:10.1128/cmr.00032-09 · Cited by 747
Human Bocavirus and Acute Wheezing in Children
Allander, T., Jartti, T., Gupta, S., Niesters, H. G. M., Lehtinen, P., usterback, R., Vuorinen, T., Waris, M., Bjerkner, A., Tiveljung-Lindell, A., et al. (2007) · Clinical Infectious Diseases · doi:10.1086/512196 · Cited by 555
Self-citationDevelopment of three multiplex RT-PCR assays for the detection of 12 respiratory RNA viruses
Bellau-Pujol, S., Vabret, A., Legrand, L., Dina, J., Gouarin, S., Petitjean-Lecherbonnier, J., Pozzetto, B., Ginevra, C., & Freymuth, F. (2005) · Journal of Virological Methods · doi:10.1016/j.jviromet.2005.01.020 · Cited by 317
Rhinovirus‐Associated Hospitalizations in Young Children
Miller, E. K., Lu, X., Erdman, D. D., Poehling, K. A., Zhu, Y., Griffin, M. R., Hartert, T. V., Anderson, L. J., Weinberg, G. A., Hall, C. B., et al. (2007) · The Journal of Infectious Diseases · doi:10.1086/511821 · Cited by 299
Translational Aspects of the Human Respiratory Virome
Mitchell, A. B., Oliver, B. G. G., & Glanville, A. R. (2016) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201606-1278ci · Cited by 59
Metadata
- Authors
- Jartti, T., Lehtinen, P., Vuorinen, T., Koskenvuo, M., & Ruuskanen, O.
- Venue
- Journal of Medical Virology
- Publisher
- Wiley
- Published
- 2004-02-13
- Volume
- 72
- Issue
- 4
- Pages
- 695-699
- ISSN
- 0146-6615 (ISSN-L)
- 1096-9071
- OpenAlex
- W1981656628
- Cited by
- 290
- References
- 4
- FWCI
- 10.35
- Type
- journal article
- Language
- en
- Open access
- closed
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- Jartti, T., Lehtinen, P., Vuorinen, T., Koskenvuo, M., & Ruuskanen, O. (2004). Persistence of rhinovirus and enterovirus RNA after acute respiratory illness in children. Journal of Medical Virology. https://doi.org/10.1002/jmv.20027
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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