Minocycline enhances MPTP toxicity to dopaminergic neurons

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Items 101–158 of 158

1. Novel SS-31 modified liposomes for improved protective efficacy of minocycline against drug-induced hearing loss
   Shanshan Hou, Yang Yang, Shuang Ying Zhou, Xiao Kuang, Yinxian Yang, Hailing Gao, Zhenjie Wang, Hongzhuo Liu · 2018 · Biomaterials Science
2. Glatiramer Acetate Reverses Motor Dysfunction and the Decrease in Tyrosine Hydroxylase Levels in a Mouse Model of Parkinson's Disease
   Madeline J. Churchill, Mark A. Cantu, Ella Anle Kasanga, Cindy Moore, Michael F. Salvatore, Charles K. Meshul · 2019 · Neuroscience
3. Minocycline protects SH‐SY5Y cells from 6‐hydroxydopamine by inhibiting both caspase‐dependent and ‐independent programmed cell death
   Bernardino Ossola, Tiina A. Lantto, Katja A. Puttonen, Raimo K. Tuominen, Atso Raasmaja, Pekka T. Männistö · 2011 · Journal of Neuroscience Research
4. Minocycline restores striatal tyrosine hydroxylase in GDNF heterozygous mice but not in methamphetamine-treated mice
   Heather A. Boger, Lawrence D. Middaugh, Ann‐Charlotte Granholm, Jacqueline F. McGinty · 2008 · Neurobiology of Disease
5. Neuropharmacological approach against MPTP (1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine)-induced mouse model of Parkinson’s disease
   Hironori Yokoyama, Hayato Kuroiwa, Jiro Kasahara, Tsutomu Araki · 2011 · Acta Neurobiologiae Experimentalis
6. Antibiotics acting as neuroprotectants via mechanisms independent of their anti-infective activities
   Matthew L. Stock, Kara J. Fiedler, Sreemoyee Acharya, Jennifer K. Lange, Gregory S.A. Mlynarczyk, Stephen J. Anderson, Garrett Reid Schmidt-McCormack, Sri Harsha Kanuri, Naveen Chandra Kondru, Matthew T. Brewer et al. · 2013 · Neuropharmacology
7. Minocycline 200 mg or 400 mg versus placebo for mild Alzheimer’s disease: the MADE Phase II, three-arm RCT
   Robert J. Howard, Olga Zubko, Richard G. Gray, Rosie Bradley, Emma Harper, Linda J. Kelly, Lynn Pank, John Tiernan O'Brien, Chris Fox, Naji Tabet et al. · 2020 · Efficacy and Mechanism Evaluation
8. A neuroprotective agent, T-817MA (1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl} azetidin-3-ol maleate), prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice
   Toshiyuki Kawasaki, Yukio Ago, Tatsuya Kitao, Tetsuaki Nashida, Akiko Takagi, Kazuhiro Takuma, Toshio Matsuda · 2008 · Neuropharmacology
9. In vivo studies on the protective role of minocycline against excitotoxicity caused by malonate or -methyl--aspartate
   Beatriz Goñi‐Allo, M RAMOS, Joaquı́n Jordán, Norberto Aguirre · 2004 · Experimental Neurology
10. Voltage-Gated Proton Channel Hv1 Regulates Neuroinflammation and Dopaminergic Neurodegeneration in Parkinson’s Disease Models
    Matthew P Neal, Eric E. Beier, Muhammad M. Hossain, Alexa M. Boyle, Jiaying Zheng, CK Kim, Isha Mhatre‐Winters, Long‐Jun Wu, Jason R. Richardson · 2023 · Antioxidants
11. An evidence update on the protective mechanism of tangeretin against neuroinflammation based on network pharmacology prediction and transcriptomic analysis
    Shuo Lv, Qiyang Chen, Zhenqing Li, Zhiqin Zhou · 2021 · European Journal of Pharmacology
12. The Role of Pathogens and Anti-Infective Agents in Parkinson’s Disease, from Etiology to Therapeutic Implications
    Si Shen, Chan Zhang, Yu-ming Xu, Chang-he Shi · 2021 · Journal of Parkinson s Disease
13. Gut microbiota and inflammation in Parkinson’s disease: Pathogenetic and therapeutic insights
    Tong Guo, Li Chen · 2022 · European Journal of Inflammation
14. CNS myeloid cells critically regulate heat hyperalgesia
    Stefanie Kälin, Kelly R. Miller, Roland E. Kälin, Marina Jendrach, Christian Witzel, Frank L. Heppner · 2018 · Journal of Clinical Investigation
15. Can FDA-Approved Immunomodulatory Drugs be Repurposed/Repositioned to Alleviate Chronic Pain?
    Kufreobong E. Inyang, Joseph K. Folger, Geoffroy O. Laumet · 2021 · Journal of Neuroimmune Pharmacology
16. Is minocycline useful for therapy of acute viral encephalitis?
    Alan C. Jackson · 2012 · Antiviral Research
17. [Minocycline for the treatment of amyotrophic lateral sclerosis: neuroprotector or neurotoxin? Reflections on another failure of translational medicine].
    Josep Gámez · 2008 · PubMed
18. A Drug Screening Reveals Minocycline Hydrochloride as a Therapeutic Option to Prevent Breast Cancer Cells Extravasation across the Blood–Brain Barrier
    Joana Godinho-Pereira, Margarida Dionísio Lopes, Ana Rita Garcia, Hugo M. Botelho, Rui Malhó, Inês Figueira, María Alexandra Brito · 2022 · Biomedicines
19. Minocycline cannot protect neurons against bilirubin-induced hyperexcitation in the ventral cochlear nucleus
    Chunyan Li, Haibo Shi, Haibo Ye, Ningying Song, Shankai Yin · 2012 · Experimental Neurology
20. Neuroprotective effects of tetracyclines on blunt head trauma: An experimental study on rats
    Özhan Merzuk Uçkun, Fatih Alagoz, Mehmet Seçer, Durmuş Oğuz Karakoyun, Ayhan Ocakcioglu, Ali Erdem Yıldırım, Fevzi Yılmaz, Mert Şahinoğlu, Denizhan Divanlıoğlu, Ali Dalgıç et al. · 2014 · Journal of Neurosciences in Rural Practice
21. The Two Different Effects of the Potential Neuroprotective Compound Minocycline on AMPA-Type Glutamate Receptors
    Lingjing Jin, Friedrich Schlesinger, Qiang Guan, Yunping Song, Zhiyu Nie · 2012 · Pharmacology
22. Human rabies therapy: lessons learned from experimental studies in mouse models.
    Alan C. Jackson, Courtney A. Scott, J Owen, Simon Chioma Weli, John P. Rossiter · 2008 · PubMed
23. Minocycline Ameliorates Neuronal Loss after Pilocarpine-Induced Status epilepticus
    Gabriel Maisonnave Arisi, Maira Licia Foresti, Andrés Montañez, Lee A. Shapiro · 2014
24. ¿Es la vieja minociclina un nuevo fármaco neuroprotector?
    Raquel M. Melero-Fernández de Mera, Eva García Martínez, Francisco-José Fernández-Gómez, Jesús Miguel Hernández-Guijo, Norberto Aguirre, María Francisca Galindo, Joaquín Jordán Bueso · 2008 · Revista de Neurología
25. 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Mammalian Models of Parkinson's Disease
    Jay S. Schneider, David W. Anderson, Emmanuel Decamp · 2008 · Elsevier eBooks
26. Neuroinflammation as a Potential Mechanism Underlying Parkinsons Disease
    Carolina Cebrián, David Sulzer · 2017 · Elsevier eBooks
27. Protective effects of minocycline, doxycycline and tetracycline on seizure and lethality in a mice cocaine toxicity model
    Tarık Bektas, Bülent Erdur, Atakan Yılmaz, Aykut Yüksel, Hasan Avci, Mert Özen, Aykut Uyanık · 2019 · The American Journal of Emergency Medicine
28. Minocycline Mitigation of Tremor Syndrome and Defect of Cognitive and Balance Induced by Harmaline
    Department of Physiology, Physiological Research Center, Iran University of Medical Sciences, Tehran, Iran., Maneshian, Marzieh, Nasirinezhad, Farinaz, Department of Physiology, Physiological Research Center, Iran University of Medical Sciences, Tehran, Iran., Mohammadi, Fatemeh, Intracellular Recording Lab, Neuroscience Research Center, Neuropharmacology Institute, Kerman University of Medical Sciences, Kerman, Iran., Behzadi, Mina, Intracellular Recording Lab, Neuroscience Research Center, Neuropharmacology Institute, Kerman University of Medical Sciences, Kerman, Iran., Asadi-Shekaari, Majid, Intracellular Recording Lab, Neuroscience Research Center, Neuropharmacology Institute, Kerman University of Medical Sciences, Kerman, Iran. et al. · 2021 · Basic and Clinical Neuroscience Journal
29. Striatal TH-immunopositive fibers recover after an intrastriatal injection of 6-hydroxydopamine in golden hamsters treated with prednisolone: Roles of tumor necrosis factor-α and inducible nitric oxide synthase in neurodegeneration
    Sebastián Rodríguez, Kazuyuki Uchida, Hiroyuki Nakayama · 2013 · Neuroscience Research
30. Caspases; Modulators of Apoptosis and Cytokine Maturation — Targets for Novel Therapies
    Melissa J. Knight, Christine J. Hawkins · 2006 · Springer eBooks
31. Anatomical location of injected microglia in different activation states and time course of injury determines survival of retinal ganglion cells after optic nerve crush
    Ahad M. Siddiqui, Thomas F. Sabljic, Alexander K. Ball · 2022 · International Journal of Neuroscience
32. Microglia alter autonomic nucleus neuronal activation after peripheral cytokine challenge
    Emily Castellanos, Luke Schwerdtfeger, Bret N. Smith, Stuart A. Tobet · 2026 · American Journal of Physiology-Cell Physiology
33. Pharmacologic Neuroprotection in Patients with Spinal Cord Injury and the Efficacy of Early Decompressive Surgery
    Kornelis A. Poelstra, Alexander Richard Vaccaro, Sonaly Rao, Alpesh A. Patel, Peter G. Whang, Mark F. Kurd, Gordon H. Stock · 2006 · Topics in Spinal Cord Injury Rehabilitation
34. The Effect of Minocycline on Allodynia Produced by Repeated Injection of Low pH Saline in Rats
    Hyun Kang, Young Cheol Woo, Chong Wha Baek, Jung‐Won Park, Yong Hun Jung, Jin Yun Kim, Gill Hoi Koo, Sun Gyoo Park · 2007 · Korean Journal of Anesthesiology
35. Gut and Parkinson’s disease
    Sujith Ovallath, Bahiya Sulthana · 2018 · Annals of Movement Disorders
36. Parkinson Disease Risk in Patients With Rosacea
    Thomas S. Wingo · 2016 · JAMA Neurology
37. Immunomodulatory Therapeutics
    David J. Graber, William F. Hickey · 2014 · Springer eBooks
38. Effect of Minocycline on Inflammatory Cell Reactions in Cerebral Contusion in Rats
    Atsushi Sawamoto, Morimichi Koshinaga, Hideki Oshima, Tomonori Harada, Isao Tsuboi, Shin Aizawa · 2011 · Journal of Nihon University Medical Association
39. Apoptosis in neurodegenerative diseases
    Jörg Bernhard Schulz · 2005 · Cambridge University Press eBooks
40. Inflammation in Parkinson’s Disease: Causes and Consequences
    Mathé Louise, André Toulouse, M. Yvonne · 2012 · InTech eBooks
41. Mechanisms of dopaminergic neurotoxin-induced blood-brain barrier disruption
    Niccole J. Larsen · 2007 · D-Scholarship@Pitt (University of Pittsburgh)
42. Systems Regulating and Inducing Dopaminergic Cell Death in Parkinson’s Disease: an Analysis of Signalling Associated with Parkinson's Disease Models
    Mount, Matthew P. · 2015 · uO Research (University of Ottawa)
43. ROLE OF MICROGLIA DURING MOTONEURON REGENERATION AND DEGENERATION: RELEVANCE FOR PATHOGENESIS AND TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS
    Sarah E. Fendrick · 2006
44. Die Rolle von Neuromelanin in der Pathogenese desidiopathischen Parkinson Syndroms
    Sebastian Geick · 2011 · Multimedialen Archiv und Publikationsserver der Christian-Albrechts-Universität zu Kiel (Christian-Albrechts-Universität zu Kiel)
45. CASPASES; MODULATORS OF APOPTOSIS AND CYTOKINE MATURATION - TARGETS FOR NOVEL THERAPIES Chapter IV
    Melissa J. Knight, Christine J. Hawkins · 2005
46. Minocycline in Cerebral Ischemia and Excitotoxicity
    Jari Koıstınaho, Milla Koistinaho · 2006 · Springer eBooks
47. Minocycline did not prevent the neurotoxic effects of amyloid β on intrinsic electrophysiological properties of hippocampal CA1 pyramidal neurons in a rat model of Alzheimer's disease
    Sharareh Daryani, Alireza Farzaei, Narges Hosseinmardi, Farideh Bahrami, Mahyar Janahmadi · 2016
48. Design of reprogrammed neuronal transplantation and nanobiomaterial-based microglial therapeutic technologies for management of Parkinson's disease
    Neal K. Bennett · 2016
49. A role for nanor in early zebrafish development and validation of a neurotoxic zebrafish model of Parkinson’s disease
    Aileen Cronin · 2018 · ARAN (University of Galway Research Repository) (Ollscoil na Gaillimhe – University of Galway)
50. Modulation of Parkinson's disease by the gut microbiota
    Ali Eshaghpour, Md. Imtaiyaz Hassan, Mohamed Sager, Yasser Ad-Dab’bagh, Mahmood Akhtar · 2018 · Ibnosina Journal of Medicine and Biomedical Sciences
51. The Immune Response in Parkinson's Disease
    Arman Lira · 2014 · uO Research (University of Ottawa)
52. Parkinson’s Disease
    John D. Loike, Vernice R. Jackson-Lewis, Serge Przedborski · 2016 · Springer eBooks
53. Minocycline treatment affects astrocyte – microglia – neuron interaction and functional compensation of motor deficits in rat model of combined fluorocitrate and 6-OHDA lesion and early Parkinson’s disease
    Katarzyna Z. Kuter, Agnieszka M. Chwastek, Martyna Paleczna, Justyna Kadłuczka, Barbara Kosmowska, Innesa Leonovich, Wiktoria Maciasz, Tomasz Lenda, Joanna Kula · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
54. Role of the prolyl isomerase Pin1 in the pathogenesis of Parkinson's disease and neuroprotection by novel targeted compounds in pre-clinical animal models of the disease
    Anamitra Ghosh · 2012 · Iowa State University Digital Repository (Iowa State University)
55. Repurposing of doxycycline as a novel therapeutic avenue for management of parkinson’s disease
    Naif H. Ali, Hayder Mutter Al-Kuraishy, Nawar R. Hussain, Ali Ismail Al-Gareeb, Ali K. Albuhadily, Tasnim S. Waheeb, Gaber El‐Saber Batiha · 2026 · Inflammopharmacology
56. Understanding the role of perivascular macrophages in Parkinson's disease pathophysiology
    Jaime R. Fuentealba · 2017 · theses.fr (ABES)
57. Minocycline-Mediated Inhibition of Microglial Activation in Neuroinflammation-Related Neuropsychiatric Disorders: Preclinical Promise and Clinical Limitations
    Sadayuki Hashioka · 2026 · International Journal of Molecular Sciences
58. The Effect of Different Microglial Activation States on the Survival of Retinal Ganglion Cells
    Ahad M. Siddiqui · 2013 · MacSphere (McMaster University)