The DOI matches its Crossref record; 64 of the 64 references it cites were found in a registry or an index.
Flagella and bacterial pathogenicity
Abstract
As locomotive organelles, flagella allow bacteria to move toward favorable environments. A flagellum consists of three parts: the basal structure (rotary motor), the hook (universal joint), and the filament (helical propeller). For ages, flagella have been generally regarded as important virulence factors, mainly because of their motility property. However, flagella are getting recognized to play multiple roles with more functions besides motility and chemotaxis. Recent evidence has pinpointed that the bacterial flagella participate in many additional processes including adhesion, biofilm formation, virulence factor secretion, and modulation of the immune system of eukaryotic cells. This mini‐review summarizes data from recent studies that elucidated how flagella, as a virulence factor, contribute to bacterial pathogenicity.
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Cites
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
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Biofilm formation as microbial development
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Pseudomonas aeruginosa Displays Multiple Phenotypes during Development as a Biofilm
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“(iii) formation of microcolonies, and (iv) biofilm maturation [19, 20].”
BackgroundCytoplasmic flagellin activates caspase-1 and secretion of interleukin 1β via Ipaf
Miao, E. A., Alpuche-Aranda, C. M., Dors, M., Clark, A. E., Bader, M. W., Miller, S. I., & Aderem, A. (2006) · Nature Immunology · doi:10.1038/ni1344 · Cited by 1,127 · cited 1×
“factor (Ipaf), which are members of the NAIPCIITA, HETE, and TP-1 proteins (NACHT)-leucine-rich repeat-containing receptor (NLR) family [50, 51].”
BackgroundThe type III secretion injectisome
Cornelis, G. R. (2006) · Nature Reviews Microbiology · doi:10.1038/nrmicro1526 · Cited by 1,067
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How Bacteria Assemble Flagella
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Cited by
Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors
Jurado-Martín, I., Sainz-Mejías, M., & McClean, S. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22063128 · Cited by 698
The Role of the Bacterial Flagellum in Adhesion and Virulence
Haiko, J., & Westerlund-Wikström, B. (2013) · Biology · doi:10.3390/biology2041242 · Cited by 589
An evaluation of the accuracy and speed of metagenome analysis tools
Lindgreen, S., Adair, K. L., & Gardner, P. P. (2016) · Scientific Reports · doi:10.1038/srep19233 · Cited by 331
Converting carbon dioxide to butyrate with an engineered strain of Clostridium ljungdahlii
Ueki, T., Nevin, K. P., Woodard, T. L., & Lovley, D. R. (2014) · mBio · doi:10.1128/mbio.01636-14 · Cited by 175
Gu, H.-J., Sun, Q.-L., Luo, J.-C., Zhang, J., & Sun, L. (2019) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2019.00183 · Cited by 57
Metadata
- Authors
- Duan, Q., Zhou, M., Zhu, L., & Zhu, G.
- Venue
- Journal of Basic Microbiology
- Publisher
- Wiley
- Published
- 2012-02-23
- Volume
- 53
- Issue
- 1
- Pages
- 1-8
- ISSN
- 0233-111X (ISSN-L)
- 1521-4028
- OpenAlex
- W1573966200
- Cited by
- 488
- References
- 64
- FWCI
- 21.11
- Type
- journal article
- Language
- en
- Open access
- closed
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