Cited by 83Yeasts and Rust Fungi StudiesMicrobial Natural Products and BiosynthesisAntimicrobial Peptides and Activities

Killer toxin from a novel killer yeast Pichia kudriavzevii RY55 with idiosyncratic antibacterial activity

Bajaj, Bijender Kumar, Raina, Sandeepu, Singh, Satbir·2013·Journal of Basic Microbiology

Abstract

The killer phenomenon of yeast may have technological implications in many areas like beverage fermentation, food technology, biological control in agriculture, and in medicine. In the present study the killer phenomenon in Pichia kudriavzevii (P. kudriavzevii RY55) is being reported for the first time. The P. kudriavzevii RY55 toxin exhibited excellent antibacterial activity against several pathogens of human health significance such as Escherichia coli, Enterococcus faecalis, Klebsiella sp., Staphylococcus aureus, Pseudomonas aeruginosa and Pseudomonas alcaligenes. Killer toxin was purified to homogeneity by using ammonium sulphate precipitation and ion exchange chromatography and characterized for few properties. P. kudriavzevii RY55 killer toxin may be of vast significance in the development of novel antimicrobial chemotherapeutic agents, new bio-based safer candidates for food preservation and biocontrol, and starter cultures for fermentation industries.

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Crossref · 10.1002/jobm.201200187

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  • The most prominent toxins produced by many biocontrol yeast strains are proteinaceous killer toxins.

    “The most prominent toxins produced by many biocontrol yeast strains are proteinaceous killer toxins (Supplementary Table 1)”

    From Biocontrol yeasts: mechanisms and applications (2019) · cites this paper as Bajaj et al. 2013

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Authors
Bajaj, B. K., Raina, S., & Singh, S.
Affiliations
University of Jammu (IN)
Corresponding author
Bajaj, Bijender Kumar
Venue
Journal of Basic Microbiology
Publisher
Wiley
Published
2012-09-07
Volume
53
Issue
8
Pages
645-656
ISSN
0233-111X (ISSN-L)
OpenAlex
W1897393515
Cited by
83
References
37
Citations by year
2026: 3 · 2025: 9 · 2024: 9 · 2023: 6 · 2022: 10 · 2021: 6 · 2020: 8 · 2019: 5 · 2018: 5 · 2017: 8 · 2016: 4 · 2015: 5 · 2014: 4 · 2013: 1
FWCI
1.28
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Basic Microbiology (publishedVersion)
  • PubMed (publishedVersion)
Funders
University Grants Commission
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Yeasts and Rust Fungi Studies
  • Health Sciences › Medicine › Pharmacology › Microbial Natural Products and Biosynthesis
  • Life Sciences › Immunology and Microbiology › Microbiology › Antimicrobial Peptides and Activities
Keywords
killer toxin, killer yeast, Candida krusei, antibacterial activity, toxin purification, Escherichia coli, Enterococcus faecalis, Staphylococcus aureus, Pseudomonas aeruginosa, Pseudomonas alcaligenes, food preservation, biological control, starter cultures, antimicrobial agents
MeSH terms
Anti-Bacterial Agents, Antifungal Agents, Chromatography, Ion Exchange, Electrophoresis, Polyacrylamide Gel, Escherichia coli, Fermentation, Hydrogen-Ion Concentration, Klebsiella, Microbial Sensitivity Tests, Mycotoxins, Pichia, Pseudomonas aeruginosa, Staphylococcus aureus, Enterococcus faecalis, Temperature, Time Factors, Pseudomonas alcaligenes

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