Killer toxin from several food-derived Debaryomyces hansenii strains effective against pathogenic Candida yeasts
Open accessAbstract
Candida yeasts are the dominant fungi in the healthy human microbiome, but are well-known for causing disease following a variety of perturbations. Evaluation of fungal populations from the healthy human gut revealed a significant negative correlation between the foodborne yeast, Debaryomyces hansenii, and Candida species. D. hansenii is reported to produce killer toxins (mycocins) effective against other yeast species. In order to better understand this phenomenon, a collection of 42 D. hansenii isolates was obtained from 22 cheeses and evaluated for killer activity against Candida albicans and Candida tropicalis over a range of temperatures and pH values. Twenty three strains demonstrated killer activity against both C. albicans and C. tropicalis, which was pH- and temperature-dependent, with no killer activity observed for any strain at pH6.5 or higher, or at ≥ 35 °C (physiological conditions in the human gastrointestinal tract). A cell-free mycocin preparation showed transient killer activity against C. albicans at 35 °C and a cheese sample containing a killer D. hansenii strain demonstrated sustained killer activity against both C. albicans and C. tropicalis. Together, these observations raise the possibility that D. hansenii could influence Candida populations in the gut.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The most prominent toxins produced by many biocontrol yeast strains are proteinaceous killer toxins.
“The most prominent toxins produced by many biocontrol yeast strains are proteinaceous killer toxins (Supplementary Table 1)”
From Biocontrol yeasts: mechanisms and applications (2019) · cites this paper as Banjara et al. 2016
Cites
Amplification and direct sequencing of fungal ribosomal RNA genes for phylogenetics
White, T. J., Bruns, T., Lee, S., & Taylor, J. (1990) · PCR Protocols · doi:10.1016/b978-0-12-372180-8.50042-1 · Cited by 36,648 · see citing works
PCR protocols — A guide to methods and applications
U.G. (1990) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(90)90252-7 · Cited by 11,750 · see citing works
Gardes, M., & Bruns, T. (1993) · Molecular Ecology · doi:10.1111/j.1365-294x.1993.tb00005.x · Cited by 10,249 · see citing works
Towards a unified paradigm for sequence‐based identification of fungi
Kõljalg, U., Nilsson, R. H., Abarenkov, K., Tedersoo, L., Taylor, A., Bahram, M., Bates, S., Bruns, T., Bengtsson-Palme, J., Callaghan, T., et al. (2013) · Molecular Ecology · doi:10.1111/mec.12481 · Cited by 3,289 · see citing works
Sardi, J. C. O., Scorzoni, L., Bernardi, T., Fusco-Almeida, A. M., & Mendes Giannini, M. J. S. (2013) · Journal of Medical Microbiology · doi:10.1099/jmm.0.045054-0 · Cited by 1,184 · see citing works
An integrated model of the recognition of Candida albicans by the innate immune system
Netea, M. G., Brown, G. D., Kullberg, B. J., & Gow, N. A. R. (2008) · Nature Reviews Microbiology · doi:10.1038/nrmicro1815 · Cited by 946 · see citing works
Calderone, R. (2012) · ASM Press eBooks · Cited by 912 · see citing works
Food fermentations: Microorganisms with technological beneficial use
Bourdichon, F., Casarégola, S., Farrokh, C., Frisvad, J. C., Gerds, M. L., Hammes, W. P., Harnett, J., Huys, G. R. B., Laulund, S., Ouwehand, A. C., et al. (2011) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2011.12.030 · Cited by 742 · see citing works
Debaryomyces hansenii — an extremophilic yeast with biotechnological potential
Breuer, U., & Harms, H. (2006) · Yeast · doi:10.1002/yea.1374 · Cited by 323 · see citing works
Rapid isolation of yeast genomic DNA: Bust n' Grab
Harju-Baker, S., Fedosyuk, H., & Peterson, K. R. (2004) · BMC Biotechnology · doi:10.1186/1472-6750-4-8 · Cited by 317 · see citing works
Studies on the Nature of the Killer Factor Produced by Saccharomyces cerevisiae
Woods, D., & Bevan, E. A. (1968) · Journal of General Microbiology · doi:10.1099/00221287-51-1-115 · Cited by 280 · see citing works
The viral killer system in yeast: from molecular biology to application
Schmitt, M., & Breinig, F. (2002) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2002.tb00614.x · Cited by 265 · see citing works
A comparison of the killer character in different yeasts and its classification
Young, T. W., & Yagiu, M. (1978) · Antonie van Leeuwenhoek · doi:10.1007/bf00400077 · Cited by 258 · see citing works
Cell Wall Receptor for Yeast Killer Toxin: Involvement of (1 → 6)-β- d -Glucan
Hutchins, K., & Bussey, H. (1983) · Journal of Bacteriology · doi:10.1128/jb.154.1.161-169.1983 · Cited by 178 · see citing works
Schulze, J., & Sonnenborn, U. (2009) · Deutsches Ärzteblatt international · doi:10.3238/arztebl.2009.0837 · Cited by 170 · see citing works
Fungi inhabiting the healthy human gastrointestinal tract: a diverse and dynamic community
Hallen‐Adams, H. E., Kachman, S. D., Kim, J., Legge, R. M., & Martínez, I. (2015) · Fungal ecology · doi:10.1016/j.funeco.2015.01.006 · Cited by 165 · see citing works
Self-citationYeasts as adjunct starters in matured Cheddar cheese
Ferreira, A. (2003) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(03)00252-6 · Cited by 163 · see citing works
Wood, H. A., & Lemke, P. A. (1980) · Mycologia · doi:10.2307/3759786 · Cited by 163 · see citing works
Phylogenetics of Saccharomycetales, the ascomycete yeasts
Suh, S., Blackwell, M., Kurtzman, C. P., & Lachance, M.-A. (2006) · Mycologia · doi:10.3852/mycologia.98.6.1006 · Cited by 156 · see citing works
Desnos‐Ollivier, M., Ragon, M., Robert, V., Raoux‐Barbot, D., Gantier, J.-C., & Dromer, F. (2008) · Journal of Clinical Microbiology · doi:10.1128/jcm.01451-08 · Cited by 154 · see citing works
Mechanisms underlying the halotolerant way of
Prista, C., Loureiro-Dias, M. C., Montiel, V., & Ramos, J. (2005) · FEMS Yeast Research · doi:10.1016/j.femsyr.2004.12.009 · Cited by 149 · see citing works
Diversity of Yeast and Mold Species from a Variety of Cheese Types
Banjara, N., Haute, M. J. S. V., & Hallen‐Adams, H. E. (2015) · Current Microbiology · doi:10.1007/s00284-015-0790-1 · Cited by 141 · see citing works
Self-citation(1→6)-β- d -Glucan as Cell Wall Receptor for Pichia membranifaciens Killer Toxin
Santos, A., Marquina, D., Leal, J. A., & Peinado, J. M. (2000) · Applied and Environmental Microbiology · doi:10.1128/aem.66.5.1809-1813.2000 · Cited by 118 · see citing works
Liu, H. (2002) · International Journal of Medical Microbiology · doi:10.1078/1438-4221-00215 · Cited by 111 · see citing works
Vasdinyei, R. (2003) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(03)00251-4 · Cited by 96 · see citing works
Walker, L. A., MacCallum, D. M., Bertram, G., Gow, N. A. R., Odds, F. C., & Brown, A. J. P. (2008) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2008.10.012 · Cited by 95 · see citing works
DETECTION OF BACTERIAL GELATINASES BY GELATIN-AGAR PLATE METHODS
Smith, H. L., & Goodner, K. (1958) · Journal of Bacteriology · doi:10.1128/jb.76.6.662-665.1958 · Cited by 93 · see citing works
Bajaj, B. K., Raina, S., & Singh, S. (2013) · Journal of Basic Microbiology · doi:10.1002/jobm.201200187 · Cited by 83 · see citing works
Yeasts associated with Sardinian ewe's dairy products
Cosentino, S., Fadda, M. E., Deplano, M., Mulargia, A. F., & Palmas, F. (2001) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(01)00572-4 · Cited by 80 · see citing works
Borelli, B. M., Ferreira, E. G., Lacerda, I. C. A., Franco, G. R., & Rosa, C. A. (2006) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-006-9151-3 · Cited by 76 · see citing works
Strain differentiation of pathogenic yeasts by the killer system
Morace, G., Archibusacci, C., Sestito, M., & Polonelli, L. (1984) · Mycopathologia · doi:10.1007/bf00436517 · Cited by 76 · see citing works
Anti-Candida activity of a novel killer toxin from the yeast Williopsis mrakii
Hodgson, V. J., Button, D., & Walker, G. M. (1995) · Microbiology · doi:10.1099/13500872-141-8-2003 · Cited by 73 · see citing works
Hernández, A., Martı́n, A., Córdoba, M. D. G., Benito, M. J., Aranda, E., & Nevado, F. P. (2007) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2007.11.044 · Cited by 70 · see citing works
Santos, A., Navascués, E., Bravo, E., & Marquina, D. (2010) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2010.12.005 · Cited by 70 · see citing works
Molecular structure of the cell wall receptor for killer toxin KT28 in Saccharomyces cerevisiae
Schmitt, M., & Radler, F. (1988) · Journal of Bacteriology · doi:10.1128/jb.170.5.2192-2196.1988 · Cited by 70 · see citing works
Nguyen, H.-V., Gaillardin, C. M., & Neuvéglise, C. (2009) · FEMS Yeast Research · doi:10.1111/j.1567-1364.2009.00510.x · Cited by 69 · see citing works
Isolation, Purification, and Characterization of a Killer Protein fromSchwanniomyces occidentalis
Chen, W.-B., Han, Y.-F., Jong, S. C., & Chang, S.-C. (2000) · Applied and Environmental Microbiology · doi:10.1128/aem.66.12.5348-5352.2000 · Cited by 68 · see citing works
Inhibition of spoilage yeasts in cheese by killer yeast Williopsis saturnus var. saturnus
Liu, S., & Tsao, M. (2009) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2009.03.009 · Cited by 62 · see citing works
Buzzini, P., & Martini, A. (2001) · Medical Mycology · doi:10.1080/mmy.39.6.479.482 · Cited by 56 · see citing works
The occurrence of killer characters in yeasts
Rosini, G. (1983) · Canadian Journal of Microbiology · doi:10.1139/m83-224 · Cited by 51 · see citing works
An Introduction to the Medically Important Candida Species
Moran, G. P., Coleman, D. C., & Sullivan, D. J. (2014) · ASM Press eBooks · doi:10.1128/9781555817176.ch2 · Cited by 50 · see citing works
Ion channel activity by Pichia membranifaciens killer toxin
Santos, A., & Marquina, D. (2003) · Yeast · doi:10.1002/yea.1069 · Cited by 43 · see citing works
Therapeutic activity of a killer peptide against experimental paracoccidioidomycosis
Travassos, L. R., Silva, L. S., Rodrigues, E. G., Conti, S., Salati, A., Magliani, W., & Polonelli, L. (2004) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkh430 · Cited by 43 · see citing works
(16)-beta-D-glucan as the cell wall binding site for Debaryomyces hansenii killer toxin
Santos, A., Marquina, D., Barroso, J. Á., & Peinado, J. M. (2002) · Letters in Applied Microbiology · doi:10.1046/j.1472-765x.2002.01053.x · Cited by 37 · see citing works
“Pecorino di Filiano” cheese as a selective habitat for the yeast species, Debaryomyces hansenii
Capece, A., & Romano, P. (2009) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2009.04.007 · Cited by 36 · see citing works
Production and characteristics of Debaryomyces hansenii killer toxin
Marquina, D., Barroso, J. Á., Santos, A., & Peinado, J. M. (2001) · Microbiological Research · doi:10.1078/0944-5013-00117 · Cited by 36 · see citing works
Characterization of the Saccharomyces cerevisae Y500-4L killer toxin
Soares, G. A. M., & Sato, H. H. (2000) · Brazilian Journal of Microbiology · doi:10.1590/s1517-83822000000400010 · Cited by 32 · see citing works
Middelbeek, E. J., Hermans, J. M. H., Stumm, C. K., & Muytjens, H. L. (1980) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.17.3.350 · Cited by 32 · see citing works
Vadkertiová, R., & Sláviková, E. (2007) · PubMed · Cited by 25 · see citing works
An Introduction to the Medically Important Candida Species
Moran, G., Coleman, D., & Sullivan, D. (2012) · Lenus, The Irish Health Repository (Dr Steevens Hospital Library) · Cited by 15 · see citing works
Vries, J. J. D., Collin, T., Bijleveld, C. M. A., Kleibeuker, J. H., & Vonk, R. J. (1988) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365528809090145 · Cited by 12 · see citing works
Immuno-assay techniques for detecting yeasts in foods
Middelhoven, W. J., & Notermans, S. H. W. (1993) · International Journal of Food Microbiology · doi:10.1016/0168-1605(93)90123-x · Cited by 10 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Biocontrol yeasts: mechanisms and applications
Freimoser, F. M., Rueda-Mejia, M. P., Tilocca, B., & Migheli, Q. (2019) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-019-2728-4 · Cited by 462 · see citing works
Forgotten fungi—the gut mycobiome in human health and disease
Huseyin, C. E., O’Toole, P. W., Cotter, P. D., & Scanlan, P. D. (2017) · FEMS Microbiology Reviews · doi:10.1093/femsre/fuw047 · Cited by 275 · see citing works
Zhang, X., Li, B., Zhang, Z., Chen, Y., & Tian, S. (2020) · Journal of Fungi · doi:10.3390/jof6030158 · Cited by 227 · see citing works
Microbial applications for sustainable space exploration beyond low Earth orbit
Koehle, A. P., Brumwell, S. L., Seto, E. P., Lynch, A. M., & Urbaniak, C. (2023) · npj Microgravity · doi:10.1038/s41526-023-00285-0 · Cited by 101 · see citing works
The halotolerant Debaryomyces hansenii , the Cinderella of non‐conventional yeasts
Prista, C., Michán, C., Miranda, I. M., & Ramos, J. (2016) · Yeast · doi:10.1002/yea.3177 · Cited by 84 · see citing works
Czarnecka, M., Żarowska, B., Połomska, X., Restuccia, C., & Cirvilleri, G. (2019) · Food Microbiology · doi:10.1016/j.fm.2019.04.004 · Cited by 83 · see citing works
The ecology of killer yeasts: Interference competition in natural habitats
Boynton, P. J. (2019) · Yeast · doi:10.1002/yea.3398 · Cited by 58 · see citing works
The potential use of Debaryomyces hansenii for the biological control of pathogenic fungi in food
Medina-Córdova, N., Rosales‐Mendoza, S., Hernández-Montiel, L. G., & Angulo, C. (2018) · Biological Control · doi:10.1016/j.biocontrol.2018.03.002 · Cited by 61 · see citing works
de Oliveira, T. C. G., Ramalhosa, E., Nunes, L., Pereira, J. A., Colla, E., & Pereira, E. L. (2017) · Innovative Food Science & Emerging Technologies · doi:10.1016/j.ifset.2017.06.003 · Cited by 58 · see citing works
Helmy, E. A. M., Soliman, S. A., Abdelghany, T. M., & Ganash, M. (2019) · Heliyon · doi:10.1016/j.heliyon.2019.e01649 · Cited by 57 · see citing works
Geronikou, A., Srimahaeak, T., Rantsiou, K., Triantafillidis, G., Larsen, N., & Jespersen, L. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.582778 · Cited by 57 · see citing works
Al-Qaysi, S. A. S., Al-Haideri, H., Thabit, Z. A., Al-Kubaisy, W. H. A. A.-R., & Ibrahim, J. A. A.-R. (2017) · International Journal of Microbiology · doi:10.1155/2017/2605382 · Cited by 49 · see citing works
Jeong, D. M., Yoo, S. J., Jeon, M., Chun, B. H., Han, D. M., Jeon, C. O., Eyun, S., Seo, Y., & Kang, H. A. (2022) · Food Microbiology · doi:10.1016/j.fm.2022.104011 · Cited by 51 · see citing works
The Effect of Disease and Season to Hepatopancreas and Intestinal Mycobiota of Litopenaeus vannamei
Li, J., Jiang, H., Li, L., Zhang, X., & Chen, J. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.00889 · Cited by 42 · see citing works
From Birth and Throughout Life: Fungal Microbiota in Nutrition and Metabolic Health
Fiers, W. D., Leonardi, I., & Iliev, I. D. (2020) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-013120-043659 · Cited by 41 · see citing works
Huang, C. S., Zhang, L., Johansen, P. G., Petersen, M. A., Arneborg, N., & Jespersen, L. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.662785 · Cited by 39 · see citing works
Effect of diet on the gut mycobiome and potential implications in inflammatory bowel disease
Buttar, J., Kon, E., Lee, A. H., Kaur, G., & Lunken, G. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2399360 · Cited by 38 · see citing works
GIMICA: host genetic and immune factors shaping human microbiota
Tang, J., Wu, X., Mou, M., Wang, C., Wang, L., Li, F., Guo, M., Yin, J., Xie, W., Wang, X., et al. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa851 · Cited by 37 · see citing works
Ezzouggari, R., Bahhou, J., Taoussi, M., Kallali, N. S., Aberkani, K., Barka, E. A., & Lahlali, R. (2024) · Agronomy · doi:10.3390/agronomy14020288 · Cited by 36 · see citing works
Use of wild yeasts as a biocontrol agent against toxigenic fungi and OTA production
de Souza, M. L., Passamani, F. R. F., Ávila, C. L. D. S., Batista, L. R., Schwan, R. F., & Silva, C. F. (2017) · Acta Scientiarum Agronomy · doi:10.4025/actasciagron.v39i3.32659 · Cited by 34 · see citing works
Çorbacı, C., & Uçar, F. B. (2018) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2018.07.121 · Cited by 33 · see citing works
Bo, B., Kim, S.-A., & Han, N. S. (2020) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2020.108508 · Cited by 30 · see citing works
Biocontrol of Pathogen Microorganisms in Ripened Foods of Animal Origin
Delgado, J., Álvarez, M., Cebrián, E., Martín, I., Roncero, E., & Rodrı́guez, M. (2023) · Microorganisms · doi:10.3390/microorganisms11061578 · Cited by 28 · see citing works
He, L., Long, C., Liu, Y., Guo, Y.-F., Xiao, N., & Tan, Z. (2017) · 3 Biotech · doi:10.1007/s13205-017-0953-9 · Cited by 27 · see citing works
Kodedová, M., & Sychrová, H. (2017) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2017.06.005 · Cited by 24 · see citing works
Lukša, J., Ravoitytė, B., Konovalovas, A., Aitmanaitė, L., Butenko, A., Yurchenko, V., Serva, S., & Servienė, E. (2017) · Toxins · doi:10.3390/toxins9080233 · Cited by 23 · see citing works
Navarrete, C., Frost, A. T., Ramos‐Moreno, L., Krum, M. R., & Martínez, J. L. (2020) · Yeast · doi:10.1002/yea.3544 · Cited by 23 · see citing works
He, Y.-S., Tang, Y., Peng, M., Xie, G., Li, W., & Tan, Z. (2019) · PLoS ONE · doi:10.1371/journal.pone.0225802 · Cited by 21 · see citing works
Wachowska, U., Sulyok, M., Wiwart, M., Suchowilska, E., Kandler, W., & Krska, R. (2022) · Food Control · doi:10.1016/j.foodcont.2022.109039 · Cited by 20 · see citing works
Reinold, J., Farahpour, F., Schoerding, A.-K., Fehring, C., Dolff, S., Konik, M., Korth, J., van Baal, L., Buer, J., Witzke, O., et al. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.848650 · Cited by 20 · see citing works
Álvarez, M., Núñez, F., Delgado, J., Andrade, M. J., & Rodrigues, P. (2022) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2022.109858 · Cited by 20 · see citing works
Bacterial and yeast microbial diversity of the ripened traditional middle east surk cheese
Esen, Y., & Çeti̇n, B. (2021) · International Dairy Journal · doi:10.1016/j.idairyj.2021.105004 · Cited by 19 · see citing works
Secondary Metabolites from Food-Derived Yeasts Inhibit Virulence of Candida albicans
Kunyeit, L., Kurrey, N. K., Anu‐Appaiah, K. A., & Rao, R. P. (2021) · mBio · doi:10.1128/mbio.01891-21 · Cited by 19 · see citing works
Yang, Y., Chen, G., Zhao, X., Cao, X., Wang, L., Mu, J., Qi, F., Liu, L., & Zhang, H. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms24010335 · Cited by 17 · see citing works
Production and Optimization of Killer Toxin in Debaryomyces hansenii Strains
Çorbacı, C., & Uçar, F. (2017) · Brazilian Archives of Biology and Technology · doi:10.1590/1678-4324-2017160339 · Cited by 17 · see citing works
Castillo, M. V., Tahmasbi, H., Pachapur, V. L., Brar, S. K., Vuckovic, D., Sitnikov, D., Arriaga, S., Blais, J., & Ramírez, A. A. (2021) · Journal of Chemical Technology & Biotechnology · doi:10.1002/jctb.6763 · Cited by 17 · see citing works
Shobana, B., Renugadevi, K., & Periakaruppan, P. (2025) · Microchemical Journal · doi:10.1016/j.microc.2025.113619 · Cited by 16 · see citing works
Wachowska, U., Stuper‐Szablewska, K., & Perkowski, J. (2020) · Polish Journal of Environmental Studies · doi:10.15244/pjoes/118427 · Cited by 17 · see citing works
Control of Mould Spoilage on Apples Using Yeasts as Biological Control Agents
Gomomo, Z., Fanadzo, M., Mewa-Ngongang, M., Hoff, J. W., van der Rijst, M., Okudoh, V. I., Kriel, J. H., & du Plessis, H. W. (2022) · Polish Journal of Food and Nutrition Sciences · doi:10.31883/pjfns/147913 · Cited by 16 · see citing works
de Ullivarri, M. F., Bulacios, G. A., Navarro, S. A., Lanza, L., Mendoza, L. M., & Chalón, M. C. (2020) · Medical Mycology · doi:10.1093/mmy/myaa011 · Cited by 14 · see citing works
The evolutionary ecology of fungal killer phenotypes
Travers-Cook, T. J., Jokela, J., & Buser, C. C. (2023) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2023.1108 · Cited by 12 · see citing works
Reyes‐Becerril, M., Angulo, C., Angulo, M., & Esteban, M. Á. (2021) · Aquaculture Research · doi:10.1111/are.15123 · Cited by 14 · see citing works
Morales-Menchén, A., Navarro, F., Guirao-Abad, J. P., Román, E., Prieto, D., Coman, I., Plá, J., & Alonso‐Monge, R. (2018) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2018.00135 · Cited by 13 · see citing works
Chacón‐Navarrete, H., Ruiz-Pérez, F., Ruiz-Castilla, F. J., & Ramos, J. (2022) · Journal of Fungi · doi:10.3390/jof8080873 · Cited by 12 · see citing works
Kuchen, B., Vázquez, F., Maturano, Y. P., Scaglia, G. J. E., Pera, L. M., & Vallejo, M. D. (2021) · OENO One · doi:10.20870/oeno-one.2021.55.2.4510 · Cited by 12 · see citing works
Wu, Y., Tang, Y., Xiao, N., Wang, C., & Tan, Z. (2020) · Medical Science Monitor · doi:10.12659/msm.920879 · Cited by 11 · see citing works
James, S. A., Parker, A., Purse, C., Telatin, A., Baker, D., Holmes, S., Durham, J., Funnell, S. G. P., & Carding, S. R. (2022) · Journal of Fungi · doi:10.3390/jof8101054 · Cited by 9 · see citing works
Dong, B., Wang, Y., Yao, Y., & Zhao, G. (2025) · Food Chemistry · doi:10.1016/j.foodchem.2025.146111 · Cited by 8 · see citing works
Kuchen, B., Paroldi, E. H., Azcona, M. S., Groff, M. C., Pera, L. M., & Vázquez, F. (2023) · OENO One · doi:10.20870/oeno-one.2023.57.1.7165 · Cited by 7 · see citing works
Biotherapeutic Potential of Probiotic Yeast Saccharomyces boulardii Against Candida albicans Biofilm
Bahuguna, N., Venugopal, D., & Rai, N. (2024) · Indian Journal of Microbiology · doi:10.1007/s12088-024-01350-2 · Cited by 7 · see citing works
Hargreaves, J., Brickle, P., & van West, P. (2018) · Fungal ecology · doi:10.1016/j.funeco.2018.08.005 · Cited by 7 · see citing works
Abu-Mejdad, N. M. J. A., Al-Saadoon, A. H., Al‐Badran, A. I., & Minati, M. H. (2020) · Bulletin of the National Research Centre/Bulletin of the National Research Center · doi:10.1186/s42269-020-00407-8 · Cited by 7 · see citing works
Commenges, A., Lessard, M.-H., Coucheney, F., Labrie, S., & Drider, D. (2023) · Food Bioscience · doi:10.1016/j.fbio.2023.103458 · Cited by 7 · see citing works
Unconventional Yeast in the Bakery Industry: A Review
Mititiuc, C., Dabija, A., & Avrămia, I. (2025) · Applied Sciences · doi:10.3390/app15179732 · Cited by 6 · see citing works
Killer yeast in winemaking: A comprehensive review
Dana, F. E., Hayar, S., & Alexandre, H. (2025) · Food Bioscience · doi:10.1016/j.fbio.2025.107631 · Cited by 7 · see citing works
Characterization of intestinal fungal community diversity in people living with HIV/AIDS (PLWHA)
Meng, P., Zhang, G., Ma, X., Ding, X., Song, X., Dang, S., Yang, R., & Xu, L. (2024) · AIDS Research and Therapy · doi:10.1186/s12981-023-00589-x · Cited by 6 · see citing works
Screening a 681-membered yeast collection for the secretion of proteins with antifungal activity
Valero, A. M., Tabatabaeifar, F., & Billerbeck, S. (2025) · New Biotechnology · doi:10.1016/j.nbt.2025.01.008 · Cited by 8 · see citing works
Neher, D. A., Andrews, T. D., Weicht, T. R., Hurd, A., & Barlow, J. (2022) · Dairy · doi:10.3390/dairy3030042 · Cited by 6 · see citing works
Ruiz-Castilla, F. J., Pérez-Fernández, A. L., Villamagua-Rojas, P. I., Chacón‐Navarrete, H., & Ramos, J. (2025) · Journal of Fungi · doi:10.3390/jof11090681 · Cited by 5 · see citing works
Pharmacological Innovations in Space: Challenges and Future Perspectives
Aksoyalp, Z. Ş., Temel, A., & Karpuz, M. (2024) · Pharmaceutical Research · doi:10.1007/s11095-024-03788-x · Cited by 6 · see citing works
Biocontrol activity of Debaryomyces hansenii against blue mold on apple and pear during cold storage
Arrarte, E., Garmendia, G., Wisniewski, M., & Vero, S. (2022) · Agrociencia Uruguay · doi:10.31285/agro.25.839 · Cited by 5 · see citing works
Czarnecka, M., Połomska, X., Restuccia, C., & Żarowska, B. (2022) · Toxins · doi:10.3390/toxins14030180 · Cited by 5 · see citing works
Bi, Y. C. T., Kouakou-Kouamé, C. A., N’guessan, F. K., Djè, M. K., & Montēt, D. (2021) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-020-02990-4 · Cited by 5 · see citing works
Urinary Fungal Microbiome and Associations With Overactive Bladder, Antibiotics and Therapy Response
Werneburg, G. T., Groß, M., Hettel, D. R., Lyon, M., McSweeney, S., Jeong, S. H., Knorr, J. M., Adler, A., Dang, T., Orji, P. U., et al. (2026) · Neurourology and Urodynamics · doi:10.1002/nau.70227 · Cited by 2 · see citing works
Gündoğdu, E., Tanrıverdi, E., & Yıldız, H. (2020) · Cited by 2 · see citing works
Optimized Selective Media Enhance the Isolation and Characterization of Gut-Derived Probiotic Yeasts
Mok, K., Popitool, K., Songla, A., Pongsuwanporn, T., Torrungruang, P., Nitisinprasert, S., Nakayama, J., & Nakphaichit, M. (2025) · Journal of Fungi · doi:10.3390/jof11120885 · Cited by 1 · see citing works
Branco, P., Maurício, E. M., Raposo, L. R., & Roma‐Rodrigues, C. (2026) · Antibiotics · doi:10.3390/antibiotics15070649 · Cited by 1 · see citing works
Killer Yeasts And Their Application
Błaszczyk, U. (2019) · Postępy Mikrobiologii - Advancements of Microbiology · doi:10.21307/pm-2019.58.4.455 · Cited by 1 · see citing works
Шагалова, В. А., Vustin, M. M., & Машенцева, Н. Г. (2023) · Хранение и переработка сельхозсырья · doi:10.36107/spfp.2023.440 · Cited by 1 · see citing works
The antifungal capacity of a 681-membered collection of environmental yeast isolatesPreprint
Valero, A. M., Tabatabaeifar, F., & Billerbeck, S. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.07.29.605670 · Cited by 1 · see citing works
Ramírez, C., & Rhaisa, A. (2016) · Lincoln (University of Nebraska)
Possibilities of using yeast in biological plant protection
Mazurkiewicz‐Zapałowicz, K., Ryplewska, R., Biedunkiewicz, A., Łopusiewicz, Ł., Gawińska-Urbanowicz, H., & Krzymińska, J. (2021) · Progress in Plant Protection · doi:10.14199/ppp-2021-035
Liu, M., Wang, H., Huang, J., Huai, Y., Yu, C., Fang, G., Zhang, M., Bo, R., Fan, K., & Li, J. (2025) · Digestion · doi:10.1159/000543337
Killer Yeast as a Novel Tool in Biotechnology: Advances in Targeted Antimicrobial Strategies
Öztürk, H. (2025) · International Journal of Agriculture Environment and Food Sciences · doi:10.31015/2025.si.11
Pengfei, M., Zhang, G., Ma, X., Ding, X., Song, X., Dang, S., Yang, R., & Xu, L. (2024) · Figshare · doi:10.6084/m9.figshare.25216793
Nikanova, D. A., Артемьева, О. А., Kolodina, E., & Dоvydenkova, M. V. (2025) · Problemy biologii produktivnyh životnyh · doi:10.25687/1996-6733.prodanimbiol.2025.4.41-50
Using yeast killer toxins as bioactive compounds for fermentation control and bioprotection of wine
Ramírez, M., Hernández, L. M., & Martínez, A. (2026) · Food Bioscience · doi:10.1016/j.fbio.2026.109332
Leng, M., Zeng, Z., Zhu, X., Guo, Y., Xu, H., Chen, W., Xiang, X., Huang, W., Huang, R., Zhao, M., et al. (2026) · Food Research International · doi:10.1016/j.foodres.2026.120020
The role of HIL1 in strain-level adhesion and immune recognition in Debaryomyces hansenii
Newhall, K. P., Bezerra, A. V. D. S., Goddard, J. M., McNeer, S. K., Mittal, A., Gutzmann, D. J., Swamy, S., Karuvannur, M., Espenschied, S. T., Zhou, J. Y., et al. (2026) · mBio · doi:10.1128/mbio.01107-26
- Authors
- Banjara, N., Nickerson, K. W., Suhr, M. J., & Hallen-Adams, H. E.
- Affiliations
- University of Nebraska–Lincoln (US)
- Venue
- International Journal of Food Microbiology
- Publisher
- Elsevier BV
- Published
- 2016-04
- Volume
- 222
- Pages
- 23-29
- ISSN
- 0168-1605 (ISSN-L)
- OpenAlex
- W2277500476
- Cited by
- 79
- References
- 52
- Citations by year
- 2026: 5 · 2025: 10 · 2024: 7 · 2023: 6 · 2022: 11 · 2021: 8 · 2020: 11 · 2019: 7 · 2018: 4 · 2017: 8 · 2016: 2
- FWCI
- 3.64
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- International Journal of Food Microbiology (acceptedVersion)
- PubMed (publishedVersion)
- Lincoln (University of Nebraska) (submittedVersion)
- Funders
- USDA National Institute of Food and Agriculture Hatch Project (NEB-31-136)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Yeasts and Rust Fungi Studies
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Keywords
- Debaryomyces hansenii, killer toxin, Candida albicans, Candida tropicalis, antifungal activity, cheese, human gut microbiome, pH and temperature dependence, yeast antagonism
- MeSH terms
- Antibiosis, Candida, Cheese, Saccharomycetales, Food Microbiology, Humans, Hydrogen-Ion Concentration, Mycotoxins, Temperature
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review