Periodontitis activates the NLRP3 inflammasome in serum and saliva

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Role of inflammasomes in the pathogenesis of periodontal disease and therapeutics

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Oral infection-inflammatory pathway, periodontitis, is a risk factor for endothelial dysfunction in patients with coronary artery disease

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ATP-dependent activation of an inflammasome in primary gingival epithelial cells infected byPorphyromonas gingivalis

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Acrolein induces NLRP3 inflammasome-mediated pyroptosis and suppresses migration via ROS-dependent autophagy in vascular endothelial cells

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Identification of the different salivary Interleukin-6 profiles in patients with periodontitis: A cross-sectional study

Isola, G., Giudice, A. L., Polizzi, A., Alibrandi, A., Murabito, P., & Indelicato, F. (2020) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2020.104997 · Cited by 99 · see citing works

Suppression of NLRP3 inflammasome by γ-tocotrienol ameliorates type 2 diabetes

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The relationship of diabetes, periodontitis and cardiovascular disease

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Independent impact of periodontitis and cardiovascular disease on elevated soluble urokinase‐type plasminogen activator receptor (suPAR) levels

Isola, G., Polizzi, A., Alibrandi, A., Williams, R. C., & Leonardi, R. M. (2020) · Journal of Periodontology · doi:10.1002/jper.20-0242 · Cited by 96 · see citing works

Salivary Levels of NLRP3 Inflammasome‐Related Proteins as Potential Biomarkers of Periodontal Clinical Status

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Analysis of galectin‐3 levels as a source of coronary heart disease risk during periodontitis

Isola, G., Polizzi, A., Alibrandi, A., Williams, R. C., & Giudice, A. L. (2021) · Journal of Periodontal Research · doi:10.1111/jre.12860 · Cited by 91 · see citing works

Down-regulation of NLRP3 inflammasome in gingival fibroblasts by subgingival biofilms: Involvement of Porphyromonas gingivalis

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Autophagy Inhibition Contributes to ROS-Producing NLRP3-Dependent Inflammasome Activation and Cytokine Secretion in High Glucose-Induced Macrophages

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Porphyromonas gingivalis Mediates Inflammasome Repression in Polymicrobial Cultures through a Novel Mechanism Involving Reduced Endocytosis

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Aggregatibacter actinomycetemcomitans targets NLRP3 and NLRP6 inflammasome expression in human mononuclear leukocytes

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CRP-Induced NLRP3 Inflammasome Activation Increases LDL Transcytosis Across Endothelial Cells

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Systemic inflammatory responses in patients with type 2 diabetes with chronic periodontitis

Mesia, R., Gholami, F., Huang, H., Clare-Salzler, M. J., Aukhil, I., Wallet, S. M., & Shaddox, L. M. (2016) · BMJ Open Diabetes Research & Care · doi:10.1136/bmjdrc-2016-000260 · Cited by 72 · see citing works

Association among serum and salivary A. actinomycetemcomitans specific immunoglobulin antibodies and periodontitis

Isola, G., Polizzi, A., Patini, R., Ferlito, S., Alibrandi, A., & Palazzo, G. (2020) · BMC Oral Health · doi:10.1186/s12903-020-01258-5 · Cited by 69 · see citing works

Upregulation of proteins of the NLRP3 inflammasome in patients with periodontitis and uncontrolled type 2 diabetes

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Periodontal Pathogens Invade Gingiva and Aortic Adventitia and Elicit Inflammasome Activation in αvβ6 Integrin-Deficient Mice

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Differential expression of inflammasome regulatory transcripts in periodontal disease

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Lacking socio‐economic status reduces subjective well‐being through perceptions of meta‐dehumanization

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Metformin ameliorates the NLPP3 inflammasome mediated pyroptosis by inhibiting the expression of NEK7 in diabetic periodontitis

Zhou, X., Wang, Q., Nie, L., Zhang, P., Zhao, P., Yuan, Q., Ji, N., Ding, Y., & Wang, Q. (2020) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2020.104763 · Cited by 58 · see citing works

NLRP3 Inflammasome Polymorphism and Macrovascular Complications in Type 2 Diabetes Patients

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A Dual Role for P2X7 Receptor during Porphyromonas gingivalis Infection

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Relationship between rheumatoid arthritis and periodontal disease in Korean adults: Data from the Sixth Korea National Health and Nutrition Examination Survey, 2013 to 2015

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NLRP3 Inflammasome Biomarker—Could Be the New Tool for Improved Cardiometabolic Syndrome Outcome

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The Inflammasome: Regulation of Nitric Oxide and Antimicrobial Host Defence

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Characterization of periodontitis in people with type 1 diabetes of 50 years or longer duration

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Endothelin, sex, and pregnancy: unique considerations for blood pressure control in females

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Periodontitis links to exacerbation of myocardial dysfunction in subjects with type 2 diabetes

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Initial periodontal treatment affects nucleotide-binding domain leucine-rich repeat-containing protein 3 inflammasome priming in peripheral blood mononuclear cells

Higuchi, K., Ziauddin, S. M., Yamashita, Y., Ozaki, Y., & Yoshimura, A. (2019) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2019.104625 · Cited by 15 · see citing works

An investigation of immunocompetence substances in normal gingival and periodontitis tissue.

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Immunostimulatory activity of low-molecular-weight hyaluronan on dendritic cells stimulated with Aggregatibacter actinomycetemcomitans or Porphyromonas gingivalis

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A Cross-Talk between Diet and the Oral Microbiome: Balance of Nutrition on Inflammation and Immune System’s Response during Periodontitis

Santonocito, S., Giudice, A., Polizzi, A., Troiano, G., Merlo, E. M., Sclafani, R., Grosso, G., & Isola, G. (2022) · Nutrients · doi:10.3390/nu14122426 · Cited by 144 · see citing works

The Role of the Oral Microbiota Related to Periodontal Diseases in Anxiety, Mood and Trauma- and Stress-Related Disorders

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Relationship between periodontitis and systemic diseases: A bibliometric and visual study

Isola, G., Polizzi, A., Serra, S., Boato, M., & Sculean, A. (2025) · Periodontology 2000 · doi:10.1111/prd.12621 · Cited by 91 · see citing works

Impact of periodontitis on gingival crevicular fluid miRNAs profiles associated with cardiovascular disease risk

Isola, G., Santonocito, S., Distefano, A., Polizzi, A., Vaccaro, M., Raciti, G., Alibrandi, A., & Volti, G. L. (2022) · Journal of Periodontal Research · doi:10.1111/jre.13078 · Cited by 74 · see citing works

Inhibition of METTL3 Alleviates NLRP3 Inflammasome Activation via Increasing Ubiquitination of NEK7

Zhou, X., Yang, X., Huang, S., Lin, G., Lei, K., Wang, Q., Lin, W., Li, H., Qi, X., Seriwatanachai, D., et al. (2024) · Advanced Science · doi:10.1002/advs.202308786 · Cited by 67 · see citing works

The Emerging Role of microRNA in Periodontitis: Pathophysiology, Clinical Potential and Future Molecular Perspectives

Santonocito, S., Polizzi, A., Palazzo, G., & Isola, G. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22115456 · Cited by 63 · see citing works

Antibiotic resistance in periodontitis patients: A systematic scoping review of randomized clinical trials

Ardila, C. M., Bedoya‐García, J., & Arrubla-Escobar, D. (2022) · Oral Diseases · doi:10.1111/odi.14288 · Cited by 63 · see citing works

Does high sugar intake really alter the oral microbiota?: A systematic review

Angarita‐Díaz, M. D. P., Fong, C., Bedoya‐Correa, C. M., & Arango, C. L. C. (2022) · Clinical and Experimental Dental Research · doi:10.1002/cre2.640 · Cited by 62 · see citing works

PAMPs and DAMPs as the Bridge Between Periodontitis and Atherosclerosis: The Potential Therapeutic Targets

Zhu, X., Huang, H., & Жао, Л. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.856118 · Cited by 60 · see citing works

The Role of Inflammasome NLPR3 in the Development and Therapy of Periodontitis

Zhao, Y., Quan, Y., Lei, T., Fan, L., Ge, X., & Hu, S. C. (2022) · International Journal of Medical Sciences · doi:10.7150/ijms.74575 · Cited by 59 · see citing works

Effect of quadrantwise versus full‐mouth subgingival instrumentation on clinical and microbiological parameters in periodontitis patients: A randomized clinical trial

Isola, G., Polizzi, A., Santonocito, S., Alibrandi, A., Pesce, P., & Kocher, T. (2024) · Journal of Periodontal Research · doi:10.1111/jre.13279 · Cited by 55 · see citing works

Periodontitis and coronavirus disease 2019

Tamimi, F., Altigani, S., & Sanz, M. (2022) · Periodontology 2000 · doi:10.1111/prd.12434 · Cited by 50 · see citing works

The association between dietary vitamin C intake and periodontitis: result from the NHANES (2009–2014)

Li, W., Song, J., & Chen, Z. (2022) · BMC Oral Health · doi:10.1186/s12903-022-02416-7 · Cited by 45 · see citing works

Impact of N‐terminal pro‐B‐type natriuretic peptide and related inflammatory biomarkers on periodontal treatment outcomes in patients with periodontitis: An explorative human randomized‐controlled clinical trial

Isola, G., Tartaglia, G. M., Santonocito, S., Polizzi, A., Williams, R. C., & Iorio‐Siciliano, V. (2023) · Journal of Periodontology · doi:10.1002/jper.23-0063 · Cited by 45 · see citing works

A20 inhibits periodontal bone resorption and NLRP3-mediated M1 macrophage polarization

Hou, L., Ye, Y., Gou, H., Tang, H., Zhou, Y., Xu, X., & Xu, Y. (2022) · Experimental Cell Research · doi:10.1016/j.yexcr.2022.113264 · Cited by 40 · see citing works

Inflammasomes and the IL-1 Family in Bone Homeostasis and Disease

Tseng, H., Samuel, S. G., Schroder, K., Lévesque, J.-P., & Alexander, K. A. (2022) · Current Osteoporosis Reports · doi:10.1007/s11914-022-00729-8 · Cited by 36 · see citing works

Effects of minimally invasive non‐surgical therapy on C‐reactive protein, lipoprotein‐associated phospholipase A 2 , and clinical outcomes in periodontitis patients: A 1‐year randomized, controlled clinical trial

Isola, G., Pesce, P., Polizzi, A., Giudice, A. L., Cicciù, M., & Scannapieco, F. A. (2024) · Journal of Periodontology · doi:10.1002/jper.23-0518 · Cited by 35 · see citing works

NLRP3 inflammasome activity and periodontal disease pathogenesis–A bidirectional relationship

Didilescu, A. C., Chinthamani, S., Scannapieco, F. A., & Sharma, A. (2024) · Oral Diseases · doi:10.1111/odi.15005 · Cited by 36 · see citing works

Elastin-Plasma Hybrid Hydrogels for Skin Tissue Engineering

Stojic, M., Ródenas‐Rochina, J., López-Donaire, M. L., de Torre, I. G., González‐Pérez, M., Rodríguez‐Cabello, J. C., Vojtová, L., Jorcano, J. L., & Velasco, D. (2021) · Polymers · doi:10.3390/polym13132114 · Cited by 34 · see citing works

Inflammation and immune response in the development of periodontal disease: a narrative review

López-Valverde, N., Quispe‐López, N., & Rueda, J. A. B. (2024) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2024.1493818 · Cited by 36 · see citing works

Identification of hub cuproptosis related genes and immune cell infiltration characteristics in periodontitis

Liu, S., Ge, J., Chu, Y., Cai, S., Gong, A., Wu, J., & Zhang, J. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1164667 · Cited by 32 · see citing works

The Role of Oxidative Stress in Periodontitis

Bullón, P., Giampieri, F., Bullón, B., & Battino, M. A. (2025) · Journal of Periodontal Research · doi:10.1111/jre.70016 · Cited by 32 · see citing works

Minimally Invasive Periodontology: A Treatment Philosophy and Suggested Approach

Ng, E., Tay, J. R. H., & Ong, M. M. A. (2021) · International Journal of Dentistry · doi:10.1155/2021/2810264 · Cited by 31 · see citing works

Accuracy of Artificial Intelligence Models in the Prediction of Periodontitis: A Systematic Review

Polizzi, A., Quinzi, V., Giudice, A. L., Marzo, G., Leonardi, R. M., & Isola, G. (2024) · JDR Clinical & Translational Research · doi:10.1177/23800844241232318 · Cited by 29 · see citing works

Association between chronic periodontitis and the risk of Alzheimer’s disease: combination of text mining and GEO dataset

Jiang, Z., Shi, Y., Zhao, W., Zhou, L., Zhang, B., Xie, Y., Zhang, Y., Tan, G., & Wang, Z. (2021) · BMC Oral Health · doi:10.1186/s12903-021-01827-2 · Cited by 30 · see citing works

One‐stage versus two‐stage technique using two splinted extra‐short implants: A multicentric split‐mouth study with a one‐year follow‐up

Menini, M., Pesce, P., Delucchi, F., Ambrogio, G., Canepa, C., Carossa, M., & Pera, F. (2022) · Clinical Implant Dentistry and Related Research · doi:10.1111/cid.13113 · Cited by 28 · see citing works

A Novel Modified-Curcumin Promotes Resolvin-Like Activity and Reduces Bone Loss in Diabetes-Induced Experimental Periodontitis

Deng, J., Golub, L. M., Lee, H., Raja, V., Johnson, F., Kucine, A. J., Lee, W., Xu, T., & Gu, Y. (2021) · Journal of Inflammation Research · doi:10.2147/jir.s330157 · Cited by 28 · see citing works

Relationship Between Periodontitis and Atrial Fibrosis in Atrial Fibrillation

Miyauchi, S., Nishi, H., Ouhara, K., Tokuyama, T., Okubo, Y., Okamura, S., Miyamoto, S., Oguri, N., Uotani, Y., Takasaki, T., et al. (2022) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2022.08.018 · Cited by 27 · see citing works

Reduction of oxidative stress blunts the NLRP3 inflammatory cascade in LPS stimulated human gingival fibroblasts and oral mucosal epithelial cells

Picciolo, G., Mannino, F., Irrera, N., Minutoli, L., Altavilla, D., Vaccaro, M., Oteri, G., Squadrito, F., & Pallio, G. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.112525 · Cited by 26 · see citing works

Impact of local drug delivery and natural agents as new target strategies against periodontitis: new challenges for personalized therapeutic approach

Viglianisi, G., Santonocito, S., Lupi, S. M., Amato, M., Spagnuolo, G., Pesce, P., & Isola, G. (2023) · Therapeutic Advances in Chronic Disease · doi:10.1177/20406223231191043 · Cited by 26 · see citing works

NLRP3 Inflammasome Expression in Gingival Crevicular Fluid of Patients with Periodontitis and Chronic Hepatitis C

Șurlin, P., Lazăr, L., Şincar, C. D., Gheorghe, D. N., Popescu, D. M., Boldeanu, M. V., Pitru, A. R., Florescu, C., & Rogoveanu, I. (2021) · Mediators of Inflammation · doi:10.1155/2021/6917919 · Cited by 22 · see citing works

Circulating MicroRNA Expression, Vitamin D, and Hypercortisolism as Predictors of Osteoporosis in Elderly Postmenopausal Women

Al‐Rawaf, H. A., Alghadir, A. H., & Gabr, S. A. (2021) · Disease Markers · doi:10.1155/2021/3719919 · Cited by 21 · see citing works

Low level of antibodies to the oral bacterium Tannerella forsythia predicts bladder cancers and Treponema denticola predicts colon and bladder cancers: A prospective cohort study

Håheim, L. L., Thelle, D. S., Rønningen, K. S., Olsen, I., & Schwarze, P. E. (2022) · PLoS ONE · doi:10.1371/journal.pone.0272148 · Cited by 20 · see citing works

Suppression of the NLRP3 Inflammasome through Activation of the Transient Receptor Potential Channel Melastatin 2 Promotes Osteogenesis in Tooth Extraction Sockets of Periodontitis

Li, Q., Wang, H., Liu, L., Weng, Y., Xu, S., Li, L., & Wang, Z. (2022) · American Journal Of Pathology · doi:10.1016/j.ajpath.2022.10.009 · Cited by 20 · see citing works

COVID‐19 Pandemic and Periodontal Practice: The Immunological, Clinical, and Economic Points of View

Darestani, M. N., Akbari, A. A., Yaghobee, S., Taheri, M., & Akbari, S. (2022) · BioMed Research International · doi:10.1155/2022/3918980 · Cited by 18 · see citing works

Autophagy attenuates osteoarthritis in mice by inhibiting chondrocyte pyroptosis and improving subchondral bone remodeling

Yan, J., Feng, G., Yang, Y., Ding, D., Ma, L., Zhao, X. S., Chen, X., Wang, H., Chen, Z., & Jin, Q. (2022) · Biomolecules and Biomedicine · doi:10.17305/bjbms.2022.7677 · Cited by 20 · see citing works

Periodontitis and COVID-19: Immunological Characteristics, Related Pathways, and Association

Qi, M., Sun, W., Wang, K., Li, W., Lin, J., Gong, J., & Wang, L. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24033012 · Cited by 21 · see citing works

Genetic Susceptibility to Periodontal Disease in Down Syndrome: A Case-Control Study

Fernández, M., de Coo, A., Quintela, I., García, E. V., Freitas, M. D., Posse, J. L., Dios, P. D., Blanco, J., Carracedo, Á., & Cruz, R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22126274 · Cited by 18 · see citing works

Periodontal effect of augmented corticotomy-assisted orthodontics versus conventional orthodontics in treatment of adult patients with bialveolar protrusion

Wang, B., Xi, W., Chen, H., Shao, J., Song, A., & Zhang, F. (2022) · BMC Oral Health · doi:10.1186/s12903-022-02107-3 · Cited by 17 · see citing works

Healing effects of monomer and dimer resveratrol in a mouse periodontitis model

Ikeda, E., Tanaka, D., Glogauer, M., Tenenbaum, H. C., & Ikeda, Y. (2022) · BMC Oral Health · doi:10.1186/s12903-022-02499-2 · Cited by 17 · see citing works

Growth differentiation factor-15 and circulating biomarkers as predictors of periodontal treatment effects in patients with periodontitis: a randomized-controlled clinical trial

Isola, G., Tartaglia, G. M., Santonocito, S., Chaurasia, A., Marya, A., & Giudice, A. L. (2023) · BMC Oral Health · doi:10.1186/s12903-023-03237-y · Cited by 17 · see citing works

The expression levels of MicroRNA-146a, RANKL and OPG after non-surgical periodontal treatment

Sattari, M., Taheri, R. A., Arefnezhad, R., & Motedayyen, H. (2021) · BMC Oral Health · doi:10.1186/s12903-021-01883-8 · Cited by 17 · see citing works

Association of salivary levels of DNA sensing inflammasomes AIM2, IFI16, and cytokine IL18 with periodontitis and diabetes

Arunachalam, L. T., Suresh, S., Lavu, V., Vedamanickam, S., Sathiyapriya, V., & Nathan, R. D. T. (2023) · Journal of Periodontology · doi:10.1002/jper.23-0184 · Cited by 16 · see citing works

Associations between Periodontitis, COVID-19, and Cardiometabolic Complications: Molecular Mechanisms and Clinical Evidence

Mainas, G., Nibali, L., Ide, M., Mahmeed, W. A., Al‐Rasadi, K., Al-Alawi, K., Banach, M., Banerjee, Y., Ceriello, A., Cesur, M., et al. (2022) · Metabolites · doi:10.3390/metabo13010040 · Cited by 16 · see citing works

Factors Associated with Periodontitis in Patients with and without HIV

Pereira, L. L., Amorim, D. V. S., Sampaio, W. B., Azevêdo, T. A. C., Cardoso, V. B. P., Lemos, F. B., da Silva, A. C. R. F., Machado, F. C., Lima, F., Neves, F. S., et al. (2023) · International Journal of Dentistry · doi:10.1155/2023/9929835 · Cited by 15 · see citing works

Effect of advanced periodontal self-care in patients with early-stage periodontal diseases on endothelial function: An open-label, randomized controlled trial

Okada, A., Murata, T., Matin, K., Ariyoshi, M., Otsuka, R., Yamashita, M., Suzuki, M., Wakiyama, R., Tateno, K., Suzuki, M., et al. (2021) · PLoS ONE · doi:10.1371/journal.pone.0257247 · Cited by 15 · see citing works

Oral Cavity is the Gateway to the Body: Role of Oral Health Professionals: A Narrative Review

Iyer, P. (2023) · Journal of the California Dental Association · doi:10.1080/19424396.2023.2193372 · Cited by 19 · see citing works

GroEL triggers NLRP3 inflammasome activation through <?A3B2 pi6?>the TLR/NF-κB p-p65 axis in human periodontal <?A3B2 pi6?>ligament stem cells

Zhang, L., Duan, M., Pu, X., Zheng, H., Ning, X., Tu, Y., Xu, C., Zhang, D., Liu, C., & Xie, J. (2024) · Acta Biochimica et Biophysica Sinica · doi:10.3724/abbs.2024050 · Cited by 14 · see citing works

Periodontal Treatment During the Blanking Period Improves the Outcome of Atrial Fibrillation Ablation

Miyauchi, S., Ouhara, K., Shintani, T., Tokuyama, T., Okubo, Y., Okamura, S., Miyamoto, S., Oguri, N., Uotani, Y., Takemura, T., et al. (2024) · Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease · doi:10.1161/jaha.123.033740 · Cited by 10 · see citing works

Short term effect of antimicrobial photodynamic therapy and probiotic L. salivarius WB21 on halitosis: A controlled and randomized clinical trial

Motta, P. D. B., Gonçalves, M. L. L., Gallo, J. M. A. S., Sobral, A. P. T., Motta, L. J., Mayer, M. P. A., Kawamoto, D., de Andrade, D. C., Santos, E. M., Fernandes, K. P. S., et al. (2024) · PLoS ONE · doi:10.1371/journal.pone.0297351 · Cited by 13 · see citing works

Pattern Recognition Receptors in Periodontal Disease: Molecular Mechanisms, Signaling Pathways, and Therapeutic Implications

Ferrara, E., & Mastrocola, F. (2024) · Journal of Molecular Pathology · doi:10.3390/jmp5040033 · Cited by 13 · see citing works

Clinical and Microbiological Efficacy of Adjunctive Systemic Quinolones to Mechanical Therapy in Periodontitis: A Systematic Review of the Literature

Ardila, C. M., & Bedoya‐García, J. (2022) · International Journal of Dentistry · doi:10.1155/2022/4334269 · Cited by 13 · see citing works

Circulating Galectin-3 and Aldosterone for Predicting Atrial Fibrillation Recurrence after Radiofrequency Catheter Ablation

Ruan, Z., Gao, R.-F., Wang, F., Chen, G., Zhu, J., Ren, Y., & Zhu, L. (2022) · Cardiovascular Therapeutics · doi:10.1155/2022/6993904 · Cited by 13 · see citing works

Significance of elevated serum and hepatic NOD-like receptor pyrin domain containing 3 (NLRP3) in hepatitis C virus-related liver disease

Aggan, H. E., Mahmoud, S., Deeb, N. E., Eleishi, I., & El-Shendidi, A. (2022) · Scientific Reports · doi:10.1038/s41598-022-22022-5 · Cited by 12 · see citing works

Biological alterations associated with the orthodontic treatment with conventional appliances and aligners: A systematic review of clinical and preclinical evidence

Gonçalves, A., Mathelié-Guinlet, Q., Ramires, F., Monteiro, F., Carvalho, Ó. S. N., Silva, F. S., Resende, A. D., & Pinho, T. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e32873 · Cited by 11 · see citing works

Diagnostic Accuracy of Salivary Biomarkers including Lactate Dehydrogenase and Hemoglobin A1c for Screening Chronic Periodontitis

Moghadam, S. A., Moghadam, F. S. A., & Alijani, E. (2022) · Disease Markers · doi:10.1155/2022/1119038 · Cited by 11 · see citing works

Orthodontic force and extracorporeal shock wave therapy: Assessment of orthodontic tooth movement and bone morphometry in a rat model

Hazan‐Molina, H., Gabet, Y., Aizenbud, I., Aizenbud, N., & Aizenbud, D. (2021) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2021.105327 · Cited by 11 · see citing works

Nigella sativa toothpaste promotes anti-inflammatory and anti-destructive effects in a rat model of periodontitis

Setiawatie, E. M., Gani, M. A., Rahayu, R. P., Ulfah, N., Kurnia, S., Augustina, E. F., & Sari, D. S. (2022) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2022.105396 · Cited by 11 · see citing works

The impact of gender and peripheral blood parameters on the characteristics of L-PRF membranes

Andrade, C. X., Amenabar, F. U., Inostroza, C., Díaz‐Calderón, P., Messina, D. R., Carrasco, N. P., & Quirynen, M. (2022) · Journal of Oral Biology and Craniofacial Research · doi:10.1016/j.jobcr.2022.08.020 · Cited by 10 · see citing works

Assessment of independent variables of periodontal disease among selected South Indian population

Anjum, S., & Rajasekar, A. (2022) · Journal of Advanced Pharmaceutical Technology amp Research · doi:10.4103/japtr.japtr_172_22 · Cited by 10 · see citing works

Dynamic Changes in Red Cell Distribution Width Can Predict Major Adverse Cardiovascular Events after PCI in Patients with Unstable Angina Pectoris: A Retrospective Cohort Study

Xiao, Q. F., Yan, D., Qin, J., Chen, W., Jiang, K., Zhao, J., Zhang, C., & Li, Y. (2022) · Disease Markers · doi:10.1155/2022/2735717 · Cited by 10 · see citing works

Effects of G-CSF on hPDLSC proliferation and osteogenic differentiation in the LPS-induced inflammatory microenvironment

Yu, H., Wang, P., Lu, H., Guan, J., Yao, F., Zhang, T., Wang, Q., & Wang, Z. (2023) · BMC Oral Health · doi:10.1186/s12903-023-03040-9 · Cited by 10 · see citing works

The relationship with and effect of oral microbiota on NLRP3 inflammatory pathway in type 2 diabetes mellitus

Wang, A., Sun, Y., Xu, M., Qin, Q., Zhu, W., & Xu, Y. (2023) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2023.105801 · Cited by 10 · see citing works

Impact of periodontitis on circulating cell-free DNA levels as a measure of cardiovascular disease

Isola, G., Polizzi, A., Mascitti, M., Santonocito, S., Ronsivalle, V., Cicciù, M., & Pesce, P. (2023) · Clinical Oral Investigations · doi:10.1007/s00784-023-05300-y · Cited by 10 · see citing works

Er:YAG laser suppresses pro-inflammatory cytokines expression and inflammasome in human periodontal ligament fibroblasts with Porphyromonas gingivalis-lipopolysaccharide stimulation

Ng, M. Y., Lin, T., Chen, S.-H., Liao, Y., Liu, C., & Yu, C. (2024) · Journal of Dental Sciences · doi:10.1016/j.jds.2023.12.011 · Cited by 9 · see citing works

Therapeutic Effect of a Novel M1 Macrophage-Targeted Nanodrug in Chronic Periodontitis Mice

Chen, Q., Zhao, Y., Xie, C., Wu, S., Ji, W., Xiao, X., & Zheng, X. (2024) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.3c00954 · Cited by 9 · see citing works

Systematic review and meta-analysis of the association of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio with periodontitis

Ghasemi, S., Mortezagholi, B., Movahed, E., Ghaedi, A., Bazrgar, A., Abdolalizadehil, S., & Khanzadeh, S. (2024) · European journal of medical research · doi:10.1186/s40001-024-02175-x · Cited by 9 · see citing works

Increased expression of advanced glycation endproducts in the gingival crevicular fluid compromises periodontal status in cigarette-smokers and waterpipe users

Ali, D. A., AlAhmari, F., Mikami, T., & Baskaradoss, J. K. (2022) · BMC Oral Health · doi:10.1186/s12903-022-02240-z · Cited by 9 · see citing works

Salivary Interleukin-6, Interleukin-1β, and C-Reactive Protein as a Diagnostic Tool for Plaque-Induced Gingivitis in Children

Salim, A., Angelova, S. T., Roussev, B. H., Sokrateva, T. D., Kiselova-Kaneva, Y. D., Peev, S., & Ivanova, D. G. (2023) · Applied Sciences · doi:10.3390/app13085046 · Cited by 8 · see citing works

Identification of Biomarkers Related to Immune Cell Infiltration with Gene Coexpression Network in Myocardial Infarction

Zhang, L., Wang, Q., & Xie, X. (2021) · Disease Markers · doi:10.1155/2021/2227067 · Cited by 8 · see citing works

Prevalence and Structure of Periodontal Disease and Oral Cavity Condition in Patients with Coronary Heart Disease (Prospective Cohort Study)

Gor, I., Nadeem, G., Bataev, H. M., & Dorofeev, A. E. (2021) · International Journal of General Medicine · doi:10.2147/ijgm.s330724 · Cited by 8 · see citing works

Identification of nine signature proteins involved in periodontitis by integrated analysis of TMT proteomics and transcriptomics

Liu, W., Qiu, W., Huang, Z.-D., Zhang, K., Wu, K., Deng, K., Chen, Y., Guo, R., Wu, B., Chen, T., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.963123 · Cited by 9 · see citing works

Salivary levels of NLRP3 protein are significantly raised in chronic periodontitis: A systematic review and meta-analysis of clinical studies

Abraham, D., Singh, A., & Goyal, A. (2023) · Journal of Indian Society of Periodontology · doi:10.4103/jisp.jisp_185_23 · Cited by 7 · see citing works

Short-term effect of ligature-induced periodontitis on cardiovascular variability and inflammatory response in spontaneously hypertensive rats

Ribeiro, A. B., da Silva, T. M., Santos-Júnior, N. N., Castania, J. A., Fazan, R., & Salgado, H. C. (2021) · BMC Oral Health · doi:10.1186/s12903-021-01885-6 · Cited by 8 · see citing works

Whole-transcriptome analysis of periodontal tissue and construction of immune-related competitive endogenous RNA network

Zhao, Q., Wen, J., Ouyang, X., Liu, J., Liu, W., Zhang, S., Lv, P., & Lou, X. (2022) · BMC Oral Health · doi:10.1186/s12903-022-02401-0 · Cited by 7 · see citing works

Synoviolin alleviates GSDMD‐mediated periodontitis by suppressing its stability

Pang, Y., Liu, L., Wu, S., Wang, J., & Liu, L. (2023) · Immunity Inflammation and Disease · doi:10.1002/iid3.880 · Cited by 7 · see citing works

Sirtuin6 and Lipoxin A4 levels are decreased in severe periodontitis

Çekici, A., Şahinkaya, S., Donmez, M. F., Türkmen, E., Balcı, N., & Toygar, H. U. (2023) · Clinical Oral Investigations · doi:10.1007/s00784-023-05330-6 · Cited by 7 · see citing works

Shared genetic architecture between periodontal disease and type 2 diabetes: a large scale genome-wide cross-trait analysis

Wu, K. C. H., Liu, L., Xu, A., Chan, Y. H., & Cheung, B. M. Y. (2024) · Endocrine · doi:10.1007/s12020-024-03766-8 · Cited by 7 · see citing works

Current Landscape of the Interrelationship Between Periodontitis, Type 2 Diabetes Mellitus, and COVID-19

Muñoz‐Carrillo, J. L., Gutiérrez-Coronado, O., Villalobos‐Gutiérrez, P. T., Valencia, M. S. V., Chávez-Ruvalcaba, F., Vázquez-Alcaraz, S. J., Rivera‐Lozada, O., & Barboza, J. J. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26188756 · Cited by 6 · see citing works

Pro-Inflammatory Markers in Serum and Saliva in Periodontitis and Hypertension

Bolyarova, T., Stefanov, L., Naseva, E., Stamatov, K., Dzhenkov, S., Stoimenov, B., Pancheva, R., Dochev, N., & Ishkitiev, N. (2025) · Medicina · doi:10.3390/medicina61061024 · Cited by 6 · see citing works

Detection of soluble urokinase type plasminogen activator receptors in children with gingivitis and normal subjects

El‐Patal, M. A., Khalil, M. A., Shipl, W. M., Barakat, I., Youssef, E. M. I., Attar, S. E., Fathi, A., & Abdallah, A. A. (2022) · BMC Oral Health · doi:10.1186/s12903-022-02478-7 · Cited by 6 · see citing works

Prevalence and correlates of periodontitis among Kenyan women planning to conceive

Oyaro, B., Lokken, E. M., Alumera, H., Hussein, S., Richardson, B. A., Mandaliya, K. N., Jaoko, W. G., Kinuthia, J., Dimba, E., Kemoli, A., et al. (2022) · BMC Oral Health · doi:10.1186/s12903-022-02243-w · Cited by 6 · see citing works

Effect of nonsurgical periodontal treatment on NLRP3, Nrf2, Caspase-1, interleukin-1B, interleukin-18 in gingival crevicular fluid of severe periodontitis

Tayman, M. A., & Kızılgün, M. (2025) · Clinical Oral Investigations · doi:10.1007/s00784-025-06574-0 · Cited by 5 · see citing works

Subgingival air polishing with trehalose powder during supportive periodontal therapy: use of a conical shaped tip during a randomized clinical trial

Kruse, A., Wölki, B. J., Woelber, J. P., Frisch, E., Vach, K., & Ratka‐Krüger, P. (2022) · BMC Oral Health · doi:10.1186/s12903-022-02109-1 · Cited by 5 · see citing works

TBXAS1 Gene Polymorphism Is Associated with the Risk of Ischemic Stroke of Metabolic Syndrome in a Chinese Han Population

Peng, J., Lu, F., Zhong, M., Zhao, Y., Wang, Z., & Zhang, W. (2022) · Disease Markers · doi:10.1155/2022/9717510 · Cited by 5 · see citing works

AR-A014418, a glycogen synthase kinase-3β inhibitor, mitigates lipopolysaccharide-induced inflammation in rat dental pulp stem cells via NLR family pyrin domain containing 3 inflammasome impairment

Xie, H., Lin, Y., & Fang, F. (2023) · Journal of Dental Sciences · doi:10.1016/j.jds.2023.03.010 · Cited by 5 · see citing works

The Role of Caspase-11 and Pyroptosis in the Regulation of Inflammation in Peri-Implantitis

Jiao, P., Li, Z., Li, B., & Jiao, X. (2023) · Journal of Inflammation Research · doi:10.2147/jir.s427523 · Cited by 5 · see citing works

The Anti-Inflammatory Effect of SDF-1 Derived Peptide on Porphyromonas gingivalis Infection via Regulation of NLRP3 and AIM2 Inflammasome

Kim, S. Y., Son, M. K., Park, J. H., Na, H. S., & Chung, J. (2024) · Pathogens · doi:10.3390/pathogens13060474 · Cited by 5 · see citing works

Short-Term Efficacy of Er:YAG Laser and Nd:YAG Laser Combined Therapy on Periodontitis

Gong, H., & Li, M. (2022) · Photobiomodulation Photomedicine and Laser Surgery · doi:10.1089/photob.2022.0045 · Cited by 5 · see citing works

Gingival Inflammation Modulates NLRP3 Inflammasome Signalling in Peripheral Blood Mononuclear Cells of PCOS Patients: A Case-Control Study

Márquez‐Arrico, C. F., Pelechá-Salvador, M., Fernández-Reyes, M., Donat, F. J. S., Perea‐Galera, L., Hermenejildo, J., Abad‐Jiménez, Z., Silvestre‐Rangil, J., Morillas, C., Víctor, V. M., et al. (2025) · Antioxidants · doi:10.3390/antiox14050507 · Cited by 4 · see citing works

The Role of Inflammasomes in Chronic Oral Inflammatory Disease and Oral Cancer: A Narrative Review

Al‐Natour, B., Rasheed, I. B., & Karim, I. A. E. (2025) · Dentistry Journal · doi:10.3390/dj13120609 · Cited by 4 · see citing works

Evaluation of inflammasomes as biomarker following non-surgical periodontal treatment

Kabacaoğlu, B., & Özener, H. Ö. (2024) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2024.105987 · Cited by 4 · see citing works

Photobiomodulation therapy facilitates transplantation of dental pulp stem cells for spinal cord injury

Zhang, X., Zhu, B., Tang, L., Yang, W., Su, L., Li, H., & Zhao, Y. (2025) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2025.104559 · Cited by 4 · see citing works

A Randomized Trial with Two Hypocaloric Diets with Different Lipid Profiles and Effects on Serum Omentin-1 Levels in Obese Subjects

de Luis, D. A., Izaola, O., Primo, D., & Aller, R. (2022) · Disease Markers · doi:10.1155/2022/6777283 · Cited by 4 · see citing works

Annual review of selected scientific literature: A report of the Committee on Scientific Investigation of the American Academy of Restorative Dentistry

Cagna, D. R., Donovan, T. E., McKee, J. R., Eichmiller, F. C., Metz, J. E., Marzola, R., Murphy, K. G., & Troeltzsch, M. (2023) · Journal of Prosthetic Dentistry · doi:10.1016/j.prosdent.2023.06.001 · Cited by 6 · see citing works

Tideglusib enhances ALP activity and upregulates RANKL expression in Osteoblast-macrophage Co-cultures within a 3D collagen scaffold

Toledano, R., Osorio, M. T., Osorio, R., Toledano, M., Jacho, D., & Yildirim-Ayan, E. D. (2024) · Journal of Dentistry · doi:10.1016/j.jdent.2024.105509 · Cited by 4 · see citing works

Periodontitis and neuropathic diseases: A literature review

Cabanillas, J., Risco, R., Munive-Degregori, A., Guerrero, M. E., Mauricio, F., & Mayta‐Tovalino, F. (2024) · Journal of International Society of Preventive and Community Dentistry · doi:10.4103/jispcd.jispcd_68_22 · Cited by 3 · see citing works

Synergistic effect of periodontitis and C-reactive protein levels on mortality: NHANES 2001–2004

Han, M., Lee, W., Ahn, S., Kang, M. H., Hwang, H. S., Kwon, S., Kim, Y., Lee, J., Kim, D. K., Kim, Y. S., et al. (2024) · PLoS ONE · doi:10.1371/journal.pone.0309476 · Cited by 3 · see citing works

Cultural and Personal Practices with Unusual Oral Findings: Three Case Reports and a Literature Review

Al-Turck, K., Aldosary, S., Alrabiah, R., Albusayes, R., & Alnamlah, S. (2021) · Clinical Cosmetic and Investigational Dentistry · doi:10.2147/ccide.s322302 · Cited by 3 · see citing works

Upregulation of proteins of the NLRP3 inflammasome in patients with periodontitis and uncontrolled type 2 diabetes

García‐Hernández, A. L., Muñoz‐Saavedra, Á. E., González‐Alva, P., Moreno‐Fierros, L., Hernández, E. L., Cifuentes‐Mendiola, S. E., & Rubio‐Infante, N. (2018) · Oral Diseases · doi:10.1111/odi.13003 · Cited by 68 · see citing works

Salivary Levels of NLRP3 Inflammasome‐Related Proteins as Potential Biomarkers of Periodontal Clinical Status

Isaza‐Guzmán, D. M., Piedrahita, V. M. M., Gutiérrez‐Henao, C., & Tobón‐Arroyave, S. I. (2017) · Journal of Periodontology · doi:10.1902/jop.2017.170244 · Cited by 91 · see citing works

Salivary Investigation of the Complex Relationship between NLRP3 Inflammasome, Leptin and Total Antioxidant Capacity in the Context of Periodontal Disease

Stănescu-Spînu, I.-I., Ilinca, R., Spînu, T. C., Miricescu, D., Dumitriu, A. S., Mocanu, B. F., Bădoiu, S. C., Coricovac, A. M., & Didilescu, A. C. (2025) · Romanian Journal of Military Medicine · doi:10.55453/rjmm.2025.128.6.7

Mechanism behind the Upregulation of Proteins Associated with the NLRP3 Inflammasome in Periodontitis and Their Role in the Immune Response in Diabetes—A Systematic Review

Ferrara, E., Converti, I., Scarola, R., Tartaglia, F. C., Gnoni, A., Isola, G., & Rapone, B. (2023) · Applied Sciences · doi:10.3390/app13148278 · Cited by 2 · see citing works

Salivary levels of NLRP3 protein are significantly raised in chronic periodontitis: A systematic review and meta-analysis of clinical studies

Abraham, D., Singh, A., & Goyal, A. (2023) · Journal of Indian Society of Periodontology · doi:10.4103/jisp.jisp_185_23 · Cited by 7 · see citing works