Drug Targeting in Cancer Chemotherapy: A Clinical Perspective

The Pharmacological Basis of Therapeutics

(1976) · American Journal of Health-System Pharmacy · doi:10.1093/ajhp/33.4.373a · Cited by 9,216 · see citing works

The Pharmacological Basis for Therapeutics

JOHNS, M. E. (1981) · Archives of Otolaryngology - Head and Neck Surgery · doi:10.1001/archotol.1981.00790410063020 · Cited by 2,011 · see citing works

Lysosomotropic Agents

De Duve, C., De Barsy, T., Poole, B., Trouet, A., Tulkens, P., & Van Hoof, F. (1974) · Biochemical Pharmacology · doi:10.1016/0006-2952(74)90174-9 · Cited by 1,901 · see citing works

Biological Diversity in Metastatic Neoplasms: Origins and Implications

Fidler, I. J., & Hart, I. R. (1982) · Science · doi:10.1126/science.7112116 · Cited by 926 · see citing works

Hydroxyldaunomycin (adriamycin) combination chemotherapy in malignant lymphoma

McKelvey, E. M., Gottlieb, J. A., Wilson, H. E., Haut, A., Talley, R. W., Stephens, R. L., Lane, M., Gamble, J. F., Jones, S. E., Grozea, P. N., et al. (1976) · Cancer · doi:10.1002/1097-0142(197610)38:4 · Cited by 819 · see citing works

Liposomes as drug carriers

Fendler, J. H., & Romero, A. (1977) · Life Sciences · doi:10.1016/0024-3205(77)90481-7 · Cited by 656 · see citing works

Heterogeneity of tumor cells from a single mouse mammary tumor.

Dexter, D. L., Kowalski, H. M., Blazar, B. A., Fligiel, Z., Vogel, R., & Heppner, G. H. (1978) · PubMed · Cited by 579 · see citing works

Adjuvant Therapy of Cancer

Jones, S. E., & Salmon, S. E. (1990) · Medical Entomology and Zoology · Cited by 532 · see citing works

Serum-induced leakage of liposome contents

Allen, T. M., & Cleland, L. G. (1980) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(80)90118-2 · Cited by 472 · see citing works

Pharmacologic rationale for regional drug delivery.

Collins, J. M. (1984) · Journal of Clinical Oncology · doi:10.1200/jco.1984.2.5.498 · Cited by 466 · see citing works

DRUG-CARRIER POTENTIAL OF LIPOSOMES IN CANCER CHEMOTHERAPY

Gregoriadis, G., Swain, C. P., Wills, E. J., & Tavill, A. S. (1974) · The Lancet · doi:10.1016/s0140-6736(74)90682-5 · Cited by 400 · see citing works

YELLOW NAILS AND LYMPHOEDEMA.

Hiscock, C., & ISDALE, I. C. (1964) · PubMed · Cited by 370 · see citing works

Biological approaches to the controlled delivery of drugs: a critical review.

Poznansky, M. J., & Juliano, R. L. (1984) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06651-7 · Cited by 355 · see citing works

Pharmacologic Principles of Cancer Treatment.

(1983) · Annals of Internal Medicine · doi:10.7326/0003-4819-98-5-694_1 · Cited by 304 · see citing works

Heterogeneity in drug sensitivity among tumor cell subpopulations of a single mammary tumor.

Heppner, G. H., Dexter, D. L., DeNucci, T., et al. (1978) · PubMed · Cited by 278 · see citing works

The impact of pain on the patient with cancer

Cleeland, C. S. (1984) · Cancer · doi:10.1002/1097-0142(19841201)54:2+ · Cited by 266 · see citing works

Amoebiasis in Ceylon.

Gr, R. (1947) · PubMed · Cited by 255 · see citing works

Polymers in controlled drug delivery

Illum, L., & Davis, S. S. (1987) · Wright eBooks · Cited by 242 · see citing works

Antibody Targeting of Liposomes: Cell Specificity Obtained by Conjugation of F(ab′) 2 to Vesicle Surface

Heath, T. D., Fraley, R. T., & Papahdjopoulos, D. (1980) · Science · doi:10.1126/science.7423203 · Cited by 237 · see citing works

Topics in Pharmaceutical Sciences

Yalkowsky, S. H. (1983) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600720233 · Cited by 221 · see citing works

Toxicity of Polyalkylcyanoacrylate Nanoparticles II: Doxorubicin-Loaded Nanoparticles

Couvreur, P., Kante, B., Grislain, L., Roland, M., & Speiser, P. P. (1982) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600710717 · Cited by 217 · see citing works

Microspheres and drug therapy: Pharmaceutical, immunological and medical aspects

Borek, F. (1985) · Journal of Immunological Methods · doi:10.1016/0022-1759(85)90291-1 · Cited by 213 · see citing works

Minireview Magnetically controlled targeted micro-carrier systems

Gupta, P., & Hung, C. T. (1989) · Life Sciences · doi:10.1016/0024-3205(89)90593-6 · Cited by 209 · see citing works

Penicillin in surgery.

Fleming, A., & Walters, W. (1947) · PubMed · Cited by 188 · see citing works

A critical evaluation of the principles governing the advantages of intra-arterial infusions

Eckman, W. W., Patlak, C. S., & Fenstermacher, J. D. (1974) · Journal of Pharmacokinetics and Biopharmaceutics · doi:10.1007/bf01059765 · Cited by 183 · see citing works

Drug carriers in biology and medicine

Gregoriadis, G. C. (1979) · Academic Press eBooks · Cited by 180 · see citing works

Recombinant Interferon Enhances Monoclonal Antibody-Targeting of Carcinoma Lesions in Vivo

Greiner, J. W., Guadagni, F., Noguchi, P. D., et al. (1987) · Science · doi:10.1126/science.3580039 · Cited by 175 · see citing works

Site–Specific (Targeted) Drug Delivery in Cancer Therapy

Poste, G. H., & Kirsh, R. L. (1983) · Nature Biotechnology · doi:10.1038/nbt1283-869 · Cited by 167 · see citing works

Suppression of tumour growth in mice by a drug–antibody conjugate using a novel approach to linkage

ROWLAND, G. F., O'NEILL, G. J., & Davies, D. A. L. (1975) · Nature · doi:10.1038/255487a0 · Cited by 165 · see citing works

Liposomes in the therapy of infectious diseases and cancer

Borek, F. (1990) · Journal of Immunological Methods · doi:10.1016/0022-1759(90)90331-o · Cited by 165 · see citing works

Cell-specific drug transfer from liposomes bearing monoclonal antibodies

Leserman, L., Machy, P., & Barbet, J. (1981) · Nature · doi:10.1038/293226a0 · Cited by 154 · see citing works

Intraarterial infusion chemotherapy for hepatic carcinoma using a totally implantable infusion pump

Buchwald, H., Grage, T. B., Vassilopoulos, P. P., et al. (1980) · Cancer · doi:10.1002/1097-0142(19800301)45:5 · Cited by 154 · see citing works

Energy expenditure in malnourished gastrointestinal cancer patients

Dempsey, D. T., Feurer, I. D., Knox, L., Crosby, L. O., Buzby, G. P., & Mullen, J. L. (1984) · Cancer · doi:10.1002/1097-0142(19840315)53:6 · Cited by 149 · see citing works

pH-sensitive immunoliposomes as an efficient and target-specific carrier for antitumor drugs.

Connor, J., & Huang, L. (1986) · PubMed · Cited by 148 · see citing works

Optimization of Drug Delivery

Fleck, R. J. (1985) · American Journal of Health-System Pharmacy · doi:10.1093/ajhp/42.11.2596a · Cited by 145 · see citing works

Differences in drug sensitivity among tumor cells from parental tumors, selected variants, and spontaneous metastases.

Tsuruo, T., & Fidler, I. J. (1981) · PubMed · Cited by 142 · see citing works

Enzyme therapy in genetic diseases

Gregoriadis, G. C., & Dean, M. F. (1979) · Nature · doi:10.1038/278603a0 · Cited by 135 · see citing works

Pilot study of amphotericin B entrapped in sonicated liposomes in cancer patients with fungal infections

Sculier, J., Coune, A., Meunier, F., Brassinne, C., Laduron, C., Hollaert, C., Collette, N., Heymans, C., & Klastersky, J. A. (1988) · European Journal of Cancer and Clinical Oncology · doi:10.1016/s0277-5379(98)90033-5 · Cited by 134 · see citing works

Arterial chemoembolization with microencapsulated anticancer drug. An approach to selective cancer chemotherapy with sustained effects

Kato, T. (1981) · JAMA · doi:10.1001/jama.245.11.1123 · Cited by 129 · see citing works

Drug delivery and targeting

Florence, A. J., & Halbert, G. (1985) · Physics in Technology · doi:10.1088/0305-4624/16/4/303 · Cited by 126 · see citing works

Adjuvant systemic therapy for resectable breast cancer.

Bonadonna, G., & Valagussa, P. (1985) · Journal of Clinical Oncology · doi:10.1200/jco.1985.3.2.259 · Cited by 121 · see citing works

Heterogenous expression of cell-surface antigens in normal epithelia and their tumours, revealed by monoclonal antibodies

Edwards, P. A. (1985) · British Journal of Cancer · doi:10.1038/bjc.1985.24 · Cited by 118 · see citing works

Clinical pharmacology of 99mTc-labeled liposomes in patients with cancer.

Lopez‐Berestein, G., Kasi, L. P., Rosenblum, M. G., et al. (1984) · PubMed · Cited by 117 · see citing works

The effects of liposome size and surface charge on liposome-mediated delivery of methotrexate-γ-aspartate to cells in vitro

Heath, T. D., Lopez, N. G., & Papahadjopoulos, D. (1985) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(85)90217-2 · Cited by 115 · see citing works

Cellular heterogeneity in tumours

Woodruff, M. F. A. (1983) · British Journal of Cancer · doi:10.1038/bjc.1983.96 · Cited by 110 · see citing works

LIPOSOMALLY ENTRAPPED SECOND ANTIBODY IMPROVES TUMOUR IMAGING WITH RADIOLABELLED (FIRST) ANTITUMOUR ANTIBODY

Beǵent, R. H. J., Green, A. J., Bagshawe, K. D., et al. (1982) · The Lancet · doi:10.1016/s0140-6736(82)90923-0 · Cited by 109 · see citing works

Modified in vivo behavior of liposomes containing synthetic glycolipids

WU, M., Robbins, J. M., Bugianesi, R. M., et al. (1981) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(81)90342-1 · Cited by 108 · see citing works

Drug streaming during intra-arterial chemotherapy

Blacklock, J. B., Wright, D. C., Dedrick, R. L., et al. (1986) · Journal of neurosurgery · doi:10.3171/jns.1986.64.2.0284 · Cited by 103 · see citing works

Opsonic Properties of Human Serum Alpha-2 HS Glycoprotein

van Oss, C. J., Gillman, C. F., Bronson, P. M., et al. (1974) · Immunological Communications · doi:10.3109/08820137409061113 · Cited by 101 · see citing works

Targeting of colloidal particles to the bone marrow

Illum, L., & Davis, S. S. (1987) · Life Sciences · doi:10.1016/0024-3205(87)90120-2 · Cited by 101 · see citing works

Increased lung uptake of liposomes coated with polysaccharides

TAKADA, M., YUZURIHA, T., Katayama, K., et al. (1984) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(84)90167-3 · Cited by 97 · see citing works

The Influence of Liposomal Encapsulation on Sodium Cromoglycate Pharmacokinetics in Man

Taylor, K. M. G., Taylor, G., Kellaway, I. W., et al. (1989) · Pharmaceutical Research · doi:10.1023/a:1015917918130 · Cited by 94 · see citing works

Radiotherapy Combined With Curative Surgery

Romsdahl, M. M. (1978) · Archives of Surgery · doi:10.1001/archsurg.1978.01370160104017 · Cited by 94 · see citing works

Clinical prospects for liposomes

Yatvin, M. B., & Lelkes, P. I. (1982) · Medical Physics · doi:10.1118/1.595079 · Cited by 93 · see citing works

Receptor-Mediated Targeting of Drugs

Gregoriadis, G., Poste, G. H., Senior, J. H., & Trouet, A. (1984) · Springer eBooks · doi:10.1007/978-1-4684-4862-7 · Cited by 92 · see citing works

Novel Approaches to Cancer Chemotherapy

(1984) · Elsevier eBooks · doi:10.1016/c2013-0-11563-2 · Cited by 92 · see citing works

Microspheres and drug therapy : pharmaceutical, immunological, and medical aspects

Davis, S. S. (1984) · Medical Entomology and Zoology · Cited by 92 · see citing works

Localization of radioiodine conjugated to the monoclonal antibody HMFG2 in human ovarian carcinoma: assessment of intravenous and intraperitoneal routes of administration.

Ward, B. G., Mather, S. J., Hawkins, L. R., et al. (1987) · PubMed · Cited by 87 · see citing works

Controlled Blocking of Hepatic Artery Flow with Enzymatically Degradable Microspheres Combined with Oncolytic Drugs

Aronsen, K. F., Hellekant, C., Holmberg, J., et al. (2008) · European Surgical Research · doi:10.1159/000128056 · Cited by 85 · see citing works

Hepatosplenic fungal infection: CT and pathologic evaluation after treatment with liposomal amphotericin B.

Shirkhoda, A., Lopez‐Berestein, G., Holbert, J. M., et al. (1986) · Radiology · doi:10.1148/radiology.159.2.3961167 · Cited by 85 · see citing works

Computed tomography in definitive radiotherapy of prostatic carcinoma, part 2: definition of target volume

Pilepich, M. V., Prasad, S. C., & Perez, C. A. (1982) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/0360-3016(82)90519-3 · Cited by 82 · see citing works

Evaluation of nanoparticles as drug-delivery systems. III: materials, stability, toxicity, possibilities of targeting, and use.

Kreuter, J. (1983) · PubMed · Cited by 82 · see citing works

Tissue distribution and tumour localization of 99m-technetium-labelled liposomes in cancer patients

Richardson, V. J., Ryman, B. E., Jewkes, R. F., et al. (1979) · British Journal of Cancer · doi:10.1038/bjc.1979.138 · Cited by 78 · see citing works

Hypoxia-mediated druGS FOR RADIATION AND CHEMOTHERAPY

ADAMS, G. E. (1981) · Cancer · doi:10.1002/1097-0142(19810801)48:3 · Cited by 77 · see citing works

Improved regional selectivity of hepatic arterial mitomycin by starch microspheres

Gyves, J. W., Ensminger, W. D., vanHarken, D., et al. (1983) · Clinical Pharmacology & Therapeutics · doi:10.1038/clpt.1983.163 · Cited by 73 · see citing works

Albumin Microspheres I: Physico-Chemical Characteristics

Gupta, P., & Hung, C. T. (1989) · Journal of Microencapsulation · doi:10.3109/02652048909031165 · Cited by 72 · see citing works

Microangiopathic hemolytic anemia observed after treatment of epidermoid carcinoma with mitomycin C and 5-fluorouracil

Gulati, S. C., Sordillo, P. P., Kempin, S. J., REICH, L. M., Magill, G. B., Scheiner, E., & Clarkson, B. D. (1980) · Cancer · doi:10.1002/1097-0142(19800501)45:9 · Cited by 72 · see citing works

Pharmacokinetic and pharmacodynamic basis for the treatment of metastatic breast cancer with high-dose medroxyprogesterone acetate

Blossey, H. C., Wander, H.-E., Köbberling, J., & Nagel, G. A. (1984) · Cancer · doi:10.1002/1097-0142(19840915)54:1+ · Cited by 71 · see citing works

Antitumor effect of actinomycin D entrapped in liposomes bearing subunits of tumor-specific monoclonal immunoglobulin M antibody.

Hashimoto, Y., Sugawara, M., Masuko, T., et al. (1983) · PubMed · Cited by 70 · see citing works

LIPOSOMES IN ARTHRITIS: A NEW APPROACH

Silva, M. D., Thomas, D. P. P., Hazleman, B. L., et al. (1979) · The Lancet · doi:10.1016/s0140-6736(79)91951-2 · Cited by 70 · see citing works

Constant infusion schedule for adriamycin: a phase I-II clinical trial of a 30-day schedule by ambulatory pump delivery system.

Lokich, J. J., Bothe, A., Zipoli, T. E., et al. (1983) · Journal of Clinical Oncology · doi:10.1200/jco.1983.1.1.24 · Cited by 70 · see citing works

Transcatheter Arterial Chemoembolization of Renal Cell Carcinoma with Microencapsulated Mitomycin C

Kato, T., Nemoto, R., Mori, H., et al. (1981) · The Journal of Urology · doi:10.1016/s0022-5347(17)54880-6 · Cited by 64 · see citing works

Albumin Microspheres II: Applications in Drug Delivery

Gupta, P., & Hung, C. T. (1989) · Journal of Microencapsulation · doi:10.3109/02652048909031166 · Cited by 62 · see citing works

Attachment of antibiotics to nanoparticles: preparation, drug-release and antimicrobial activity in vitro

Henry-Michelland, S., Alonso, M. J., Andremont, A., MAINCEN, P., Sauzieres, J., & Couvreur, P. (1987) · International Journal of Pharmaceutics · doi:10.1016/0378-5173(87)90080-9 · Cited by 62 · see citing works

Stability of doxorubicin-liposomes on storage: as an aqueous dispersion, frozen or freeze-dried

VANBOMMEL, E., & Crommelin, D. J. A. (1984) · International Journal of Pharmaceutics · doi:10.1016/0378-5173(84)90030-9 · Cited by 61 · see citing works

Liposomes in the therapy of infectious diseases and cancer

(1988) · Journal of Cellular Biochemistry · doi:10.1002/jcb.240380607 · Cited by 61 · see citing works

Radionuclide-labelled liposomes—A new lymph node imaging agent

Osborne, M. P., Richardson, V. J., Jeyasing, K., et al. (1979) · International Journal of Nuclear Medicine and Biology · doi:10.1016/0047-0740(79)90001-9 · Cited by 56 · see citing works

Stage III endometrial carcinoma. A review of 90 cases

Mackillop, W. J., & Pringle, J. F. (1985) · Cancer · doi:10.1002/1097-0142(19851115)56:10 · Cited by 56 · see citing works

Acute side effects and late complications after radiotherapy of localized carcinoma of the prostate

Dewit, L. G. H., Ang, K. K., & van der Schueren, E. (1983) · Cancer Treatment Reviews · doi:10.1016/0305-7372(83)90006-3 · Cited by 53 · see citing works

Organ-Selective Action of an Antitumor Drug: Pharmacologic Studies of Liposome-Encapsulated β-Cytosine Arabinoside Administered via the Respiratory System of the Rat2

McCullough, H., & Juliano, R. L. (1979) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/63.3.727 · Cited by 53 · see citing works

Phase I study of hepatic arterial degradable starch microspheres and mitomycin.

Ensminger, W. D., Gyves, J. W., Stetson, P. L., et al. (1985) · PubMed · Cited by 52 · see citing works

Clinical trials in cancer chemotherapy

Carter, S. K. (1977) · Cancer · doi:10.1002/1097-0142(197707)40:1+ · Cited by 49 · see citing works

Reticulo-endothelial activity in humans with cancer

Magarey, C. J., & Baum, M. S. (1970) · British journal of surgery · doi:10.1002/bjs.1800571013 · Cited by 49 · see citing works

Monoclonal Antibody Imaging of Human Melanoma

Lotze, M. T., Carrasquillo, J. A., Weinstein, J. N., et al. (1986) · Annals of Surgery · doi:10.1097/00000658-198609000-00002 · Cited by 47 · see citing works

Antibody‐mediated targeting of liposomes to red cells in vivo

Singhal, A. K., & Gupta, C. M. (1986) · FEBS Letters · doi:10.1016/0014-5793(86)80632-9 · Cited by 47 · see citing works

Increased lymphatic delivery of bleomycin by microsphere in oil emulsion and its effect on lymph node metastasis

Matsuru, H., Muranishi, S., Sezaki, H., et al. (1979) · International Journal of Pharmaceutics · doi:10.1016/0378-5173(79)90031-0 · Cited by 43 · see citing works

Cell proliferation in fibrocystic disease and postmenopausal breast ducts measured by thymidine labeling

Meyer, J. S., & Connor, R. E. (1982) · Cancer · doi:10.1002/1097-0142(19820815)50:4 · Cited by 41 · see citing works

Role of intramuscular administration of water-in-oil emulsions as a method for increasing the delivery of anticancer to regional lymphatics

Hashida, M., Egawa, M., Muranishi, S., et al. (1977) · Journal of Pharmacokinetics and Biopharmaceutics · doi:10.1007/bf01065397 · Cited by 41 · see citing works

Liposomal Amphotericin B in the Treatment of Fungal Infections

Lopez‐Berestein, G. (1986) · Annals of Internal Medicine · doi:10.7326/0003-4819-105-1-130 · Cited by 40 · see citing works

A comparison of iodine and indium labelled anti CEA intact antibody, F(ab)2 and Fab fragments by imaging tumour xenografts

Andrew, S. M., Perkins, A. C., Pimm, M. V., et al. (1988) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/bf02574776 · Cited by 39 · see citing works

Temporary intestinal hypoxia induced by degradable microspheres

Arfors, K. ‐., Forsberg, J. O., Larsson, B., et al. (1976) · Nature · doi:10.1038/262500a0 · Cited by 39 · see citing works

The acute toxicities of chemotherapy

Spiegel, R. J. (1981) · Cancer Treatment Reviews · doi:10.1016/s0305-7372(81)80017-5 · Cited by 39 · see citing works

Tumor uptake of 67Ga-carrying liposomes

Ogihara, I., Kojima, S., & Jay, M. (1986) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/bf00261406 · Cited by 38 · see citing works

Specific in vitro and in vivo drug localisation to tumour cells using a hybrid-hybrid monoclonal antibody recognising both carcinoembryonic antigen (CEA) and vinca alkaloids

Corvalan, J. R. F., Smith, W., Gore, V., et al. (1987) · Cancer Immunology Immunotherapy · doi:10.1007/bf00205590 · Cited by 37 · see citing works

Clinical pharmacokinetics of doxorubicin in hepatoma patients after a single intravenous injection of free or nanoparticle-bound anthracycline

Rolland, A. P. (1989) · International Journal of Pharmaceutics · doi:10.1016/0378-5173(89)90330-x · Cited by 36 · see citing works

Arterial chemoembolization with cisplatin microcapsules

Okamoto, Y., Konno, A., Togawa, K., et al. (1986) · British Journal of Cancer · doi:10.1038/bjc.1986.61 · Cited by 35 · see citing works

An application of water-in-oil and gelatin-microsphere-in-oil emulsions to specific delivery of anticancer agent into stomach lymphatics

Hashida, M., Takahashi, Y., Muranishi, S., et al. (1977) · Journal of Pharmacokinetics and Biopharmaceutics · doi:10.1007/bf01065398 · Cited by 34 · see citing works

Immunoliposomes: Preparation, properties, and applications

Sullivan, S. M., Connor, J., & Huang, L. (1986) · Medicinal Research Reviews · doi:10.1002/med.2610060203 · Cited by 34 · see citing works

Increased therapeutic effect of vinca alkaloids targeted to tumour by a hybrid-hybrid monoclonal antibody

Corvalan, J. R. F., Smith, W., Gore, V., et al. (1987) · Cancer Immunology Immunotherapy · doi:10.1007/bf00205591 · Cited by 33 · see citing works

Controlled Drug Delivery

(2019) · CRC Press eBooks · doi:10.1201/9780429262234 · Cited by 33 · see citing works

Pharmacokinetics of Intra-Arterial Chemotherapy

Stephens, F. O. (1983) · Recent results in cancer research/Recent Results in Cancer Research · doi:10.1007/978-3-642-82025-0_1 · Cited by 31 · see citing works

Receptor mediated targeting of drugs

(1986) · General Pharmacology The Vascular System · doi:10.1016/0306-3623(86)90239-9 · Cited by 31 · see citing works

Ultrastructural Disposition of Adriamycin-Associated Magnetic Albumin Microspheres in Rats

Gupta, P., Hung, C., & Rao, N. S. (1989) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600780406 · Cited by 30 · see citing works

Drug-targeting by monoclonal antibodies

Embleton, M. (1987) · British Journal of Cancer · doi:10.1038/bjc.1987.44 · Cited by 28 · see citing works

Regional cerebral blood flow in various types of brain tumor

Kuroda, K., Olsen, T. S., & Lassen, N. A. (1982) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.1982.tb04513.x · Cited by 28 · see citing works

The Effect of Cytotoxic Drugs on Neutrophil Phagocytosis in Vitro and in Patients with Acute Myelogenous Leukaemia

Davies, J. E., Whittaker, J. A., & Khurshid, M. (1976) · British Journal of Haematology · doi:10.1111/j.1365-2141.1976.tb01871.x · Cited by 28 · see citing works

Passive and active vectoring with microparticles: Localisation and drug release

Tomlinson, E. (1985) · Journal of Controlled Release · doi:10.1016/0168-3659(85)90060-4 · Cited by 26 · see citing works

A potential application for the intracerebral injection of drugs entrapped within liposomes in the treatment of human cerebral gliomas.

McKeran, R. O., Firth, G., Oliver, S., Uttley, D., & O'Laoire, S. (1985) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.48.12.1213 · Cited by 26 · see citing works

Targeting of drugs with molecules, cells and liposomes

Gregoriadis, G. C. (1983) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(83)90413-3 · Cited by 23 · see citing works

MICROENCAPSULATED MITOMYCIN-C THERAPY IN RENAL-CELL CARCINOMA

Kato, T., Nemoto, R., Mori, H., et al. (1979) · The Lancet · doi:10.1016/s0140-6736(79)91540-x · Cited by 21 · see citing works

Immunoconjugates: Applications in Targeted Drug Delivery for Cancer Therapy

Ram, B. P., & Tyle, P. (1987) · Pharmaceutical Research · doi:10.1023/a:1016443725167 · Cited by 20 · see citing works

New Methodology for Liposome Targeting to Specific Cellsa

Papahadjopoulos, D., Heath, T. D., Bragman, K., et al. (1985) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1985.tb18412.x · Cited by 20 · see citing works

Chemoembolization: Transcatheter Management of Neoplasms

Chuang, V. P. (1981) · JAMA · doi:10.1001/jama.1981.03310360043023 · Cited by 20 · see citing works

Clinical anticancer pharmacology: Some pharmacokinetic considerations

Levin, V. A. (1986) · Cancer Treatment Reviews · doi:10.1016/0305-7372(86)90014-9 · Cited by 19 · see citing works

Radiotherapy and adjuvant combination chemotherapy (6-aminonicotinamide and 6-mercaptopurine).

Martin, D. S., Kligerman, M. M., & Fugmann, R. A. (1958) · PubMed · Cited by 18 · see citing works

Cancer Chemotherapy: Alternative Routes of Drug Administration. A Review

Keizer, H. J., & Pinedo, H. M. (1985) · Cancer Drug Delivery · doi:10.1089/cdd.1985.2.147 · Cited by 18 · see citing works

Formulation and Characterization of Magnetic Polyglutaraldehyde Nanoparticles as Carriers for Poly-l-Lysine-Methotrexate

Hung, C. T., McLeod, A. D., & Gupta, P. (1990) · Drug Development and Industrial Pharmacy · doi:10.3109/03639049009114899 · Cited by 18 · see citing works

Surgical chemotherapy against lymph node metastases: an experimental study.

Tanigawa, N., Satomura, K., Hikasa, Y., et al. (1980) · PubMed · Cited by 18 · see citing works

Albumin microspheres. V. Evaluation of parameters controlling the efficacy of magnetic microspheres in the targeted delivery of adriamycin in rats

Gupta, P., & Cheung-Tak, H. (1990) · International Journal of Pharmaceutics · doi:10.1016/0378-5173(90)90064-b · Cited by 17 · see citing works

Pharmacologic Studies of Intra-Hepatic Artery Chemotherapy with Degradable Starch Microspheres

PFEIFLE, C. E., Howell, S. B., Ashburn, W. L., et al. (1986) · Cancer Drug Delivery · doi:10.1089/cdd.1986.3.1 · Cited by 17 · see citing works

Antitumor effect of adriamycin entrapped in liposomes conjugated with monoclonal antibody against tumor-associated antigen of bovine leukemia cells.

Onuma, M., Odawara, T., Watarai, S., et al. (1986) · PubMed · Cited by 16 · see citing works

Reduction in doxorubicin toxicity following liposomal delivery

Sells, R. A., Gilmore, I. T., Owen, R. R., et al. (1987) · Cancer Treatment Reviews · doi:10.1016/0305-7372(87)90034-x · Cited by 16 · see citing works

99mc-labelled liposomes preparation of radiopharmaceutical and its distribution in a hepatoma patient

Richardson, V. J., Ryman, B. E., Jewkes, R. F., et al. (1978) · International Journal of Nuclear Medicine and Biology · doi:10.1016/0047-0740(78)90041-4 · Cited by 15 · see citing works

Pharmacokinetics of Amphotericin B in Patients Receiving Repeated Intravenous High Doses of Amphotericin B Entrapped into Sonicated Liposomes

Sculier, J., Delcroix, C., Brassinne, C., et al. (1989) · Journal of Liposome Research · doi:10.3109/08982108909035988 · Cited by 14 · see citing works

Drug Delivery Systems—2. Site‐Specific Drug Delivery Utilizing Monoclonal Antibodies

Ranade, V. (1989) · The Journal of Clinical Pharmacology · doi:10.1002/j.1552-4604.1989.tb03247.x · Cited by 14 · see citing works

Mastectomy as an Adjunct to Combination Chemotherapy

Morris, D. M. (1978) · Archives of Surgery · doi:10.1001/archsurg.1978.01370150054009 · Cited by 13 · see citing works

Biodistribution of methotrexate-monoclonal antibody conjugates and complexes: experimental and clinical studies

Pimm, M. V., Clegg, J. A., Caten, J. E., et al. (1987) · Cancer Treatment Reviews · doi:10.1016/0305-7372(87)90039-9 · Cited by 13 · see citing works

Secular and age distribution of scrotal cancer in connecticut and a review of United States literature

Roush, G. C., Schymura, M. J., & Flannery, J. (1984) · Cancer · doi:10.1002/1097-0142(19840801)54:3 · Cited by 12 · see citing works

Cancer Chemotherapy

Carter, S. K. (1980) · Drugs · doi:10.2165/00003495-198020050-00003 · Cited by 11 · see citing works

Methods of drug delivery

Ihler, G. M. (1986) · Pergamon Press eBooks · Cited by 10 · see citing works

Biological response modifiers and cancer therapy

Chiao, J.-W. (1988) · Medical Entomology and Zoology · Cited by 10 · see citing works

The treatment of gastric cancer with combined surgical resection and chemotherapy

Franz, J. L., & Cruz, A. B. (1977) · Journal of Surgical Oncology · doi:10.1002/jso.2930090206 · Cited by 10 · see citing works

Prophylactic cranial irradiation for small-cell lung cancer: Long-term results

Johnson, J. R., Morgan, D. A. L., & Holland, I. M. (1989) · Clinical Oncology · doi:10.1016/s0936-6555(89)80007-x · Cited by 10 · see citing works

Evaluation of therapeutic arterial embolization in renal cell carcinoma using microencapsulated mitomycin C

Nemoto, R., Kato, T., Iwata, K., et al. (1981) · Urology · doi:10.1016/0090-4295(81)90253-3 · Cited by 10 · see citing works

Tissue distribution of sialoglycopeptide-bearing liposomes in rats.

Saito, K., Ando, J., Yoshida, M., et al. (1988) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.36.4187 · Cited by 9 · see citing works

Will 1988 Be ‘The Year of the Liposome’?

Klausner, A. (1988) · Nature Biotechnology · doi:10.1038/nbt0188-20 · Cited by 9 · see citing works

Distribution in man of 111In-labelled liposomes containing a water-insoluble antimitotic agent.

Frühling, J. G., Coune, A., Ghanem, G. E., et al. (1984) · PubMed · Cited by 8 · see citing works

The effect of combination chemotherapy on the reticuloendothelial system in man

Domellöf, L., Athlin, L., & BERGHEM, L. E. R. (1978) · Cancer Letters · doi:10.1016/s0304-3835(78)80003-2 · Cited by 7 · see citing works

Phase I Study, with Pharmacokinetic Analysis, of Intravenous Administration of 6-Aminochrysene Entrapped into Sonicated Liposomes in Patients with Advanced Cancer

Soulier, J.-P., Brassine, C., Laduron, C., et al. (1989) · Journal of Liposome Research · doi:10.3109/08982108909035990 · Cited by 7 · see citing works

Liposomes as aids to tumour detection

BARRATT, G. M., Ryman, B. E., Chester, K. A., et al. (1984) · Biochemical Society Transactions · doi:10.1042/bst0120348 · Cited by 6 · see citing works

Pilot Study of Intra-Arterial Floxuridine, Mitomycin and Doxorubicin in Combination with Degradable Starch Microspheres to Treat Primary and Metastatic Tumors of the Liver

PFEIFLE, C. E., Howell, S. B., & Bookstein, J. J. (1985) · Cancer Drug Delivery · doi:10.1089/cdd.1985.2.305 · Cited by 6 · see citing works

Minimal residual neoplastic disease—concept, pathogenesis, and supplementary therapeutic possibilities

Prindull, G. (1986) · Cancer Treatment Reviews · doi:10.1016/0305-7372(86)90004-6 · Cited by 5 · see citing works

Application of Regression Analysis in the Evaluation of Tumor Response following the Administration of Adriamycin either as a Solution or Via Albumin Microspheres to the Rat

Gupta, P., Hung, C. T., & Lam, F. C. (1990) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600790719 · Cited by 5 · see citing works

Failure to demonstrate tumour-specific leucocyte migration inhibition in vitro by cryostat sections of breast cancer tissue.

Petrini, B., Bergstrand, A., Wasserman, J., et al. (1977) · PubMed · Cited by 5 · see citing works

Pharmacokinetic evaluation of local drug delivery: the intratesticular and intrarenal administration of acenocoumarol in the rat

Daemen, M. J. A. P., Vervoort-Peters, H. T. M., & Thijssen, H. H. W. (1988) · Journal of Pharmacy and Pharmacology · doi:10.1111/j.2042-7158.1988.tb05245.x · Cited by 4 · see citing works

Smart nanoparticles for cancer therapy

Sun, L., Liu, H., Ye, Y., Lei, Y., Islam, R., Tan, S., Tong, R., Miao, Y.-B., & Cai, L. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01642-x · Cited by 1,073 · see citing works

Smart nanocarrier-based drug delivery systems for cancer therapy and toxicity studies: A review

Hossen, S., Hossain, M. K., Basher, M. K., Mia, M. N. H., Rahman, M. T., & Uddin, M. J. (2019) · Journal of Advanced Research · doi:10.1016/j.jare.2018.06.005 · Cited by 998 · see citing works

Review on overview of colon targeting drug dilivery system

Mahajan, K., Thakur, N., Thakur, K., et al. (2021) · Journal of Emerging Technologies and Innovative Research

Review On Targeted Drug Delivery System And Its Carriers As Drug Targeted To A Specific Organ

-, M. G. M., -, P. P. S., -, K. S. B., et al. (2023) · International Journal For Multidisciplinary Research · doi:10.36948/ijfmr.2023.v05i02.1973

Research and Application of Oral Colon Targeted Drug Delivery System

Bi, Y. S., Zhang, X. X., Cao, X., et al. (2014) · Advanced materials research · doi:10.4028/www.scientific.net/amr.1053.456 · Cited by 4 · see citing works

Analysis on the current status of targeted drug delivery to tumors

Kwon, I. K., Lee, S. C., Han, B., & Park, K. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.07.010 · Cited by 404 · see citing works

Colon Targeted Drug Delivery Systems -An Overview

Kumar, P., & Mishra, B. (2008) · Current Drug Delivery · doi:10.2174/156720108784911712 · Cited by 70 · see citing works